Synthesis and fungicidal activity of 2-benzoylaminobenzimidazole complex compounds with copper

2013 ◽  
Vol 86 (2) ◽  
pp. 285-288 ◽  
Author(s):  
G. E. Chikisheva ◽  
Yu. E. Sapozhnikov ◽  
R. Kh. Mudarisova ◽  
L. I. Buslaeva ◽  
Z. B. Galieva ◽  
...  
Keyword(s):  
Fungicidal Activity ◽  
Complex Compounds

scholarly journals MOLECULAR COMPLEXES OF MONOAMMONIUM SALT OF GLYCYRRHIZIC ACID WITH SOME UREA AND THEIR ANTIBIOTIC ACTIVITY

2021 ◽  
Vol 19 (3) ◽  
pp. 160-167
Author(s):  
Yu.T. Isaev ◽  
◽  
I.R. Askarov ◽  
S.A. Rustamov ◽  
D.U. Egamberdiev ◽  
...  
Keyword(s):  
Glycyrrhizic Acid ◽  
Fungicidal Activity ◽  
Pathogenic Fungus ◽  
Equilibrium Constants ◽  
Molecular Complexes ◽  
Complex Compounds ◽  
Antibiotic Activity ◽  
Polar Groups ◽  
Ir Spectroscopic ◽  
Complexation Process

This article reports on obtaining the inclusion compounds of the monoammonium-glycyrrhizin salts with urea, thiourea and methylolthiourea. The compounds were obtained by the liquid phase way, and their structures were characterized by the UV- and IR-Spectroscopic methods. Proceeding from the spectral data, it was concluded that the complexation occurs through the interaction of polar groups of the components. The composition of the complexes was studied using the method of isomolar series. Equilibrium constants and changes in Gibbs free energy of the complexation process were also calculated. The biological activity of complex compounds was studied on the example of fungicidal activity of one of the most common pathogenic fungus Fusarium. The obtained compounds can be used as as fungicides and stimulants in agriculture.

Aktivitas Antifungi Air Perasan Bawang Merah (Allium ascalonicum L.) Terhadap Candida albicans Secara In Vitro

2017 ◽  
Vol 9 (2) ◽  
pp. 71
Author(s):  
Nurhasanah Nurhasanah ◽  
Fauzia Andrini ◽  
Yulis Hamidy
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Allium Sativum ◽  
Fungicidal Activity ◽  
Positive Control ◽  
Negative Control ◽  
Randomized Design ◽  
Significant Difference ◽  
Completely Randomized Design

Shallot (Allium ascalonicum L.) has been known as traditional medicine. Shallot which has same genus with garlic(Allium sativum L.) contains allicin that is also found in garlic and has been suspected has fungicidal activity toCandida albicans. It is supported by several researches. Therefore, shallot is suspected has antifungal activity too.The aim of this research was to know antifungal activity of shallot’s water extortion againsts Candida albicans invitro. This was a laboratory experimental research which used completely randomized design, with diffusion method.Shallot’s water extortion was devided into three concentrations, there were 50%, 100% and 200%. Ketoconazole 2%was positive control and aquadest was negative control. The result of this research based on analysis of varians(Anova), there was significant difference between several treatments and was confirmed with Duncan New MultipleRange Test (DNMRT) p<0,05, there was significant difference between 100% shallot’s water extortion with othertreatments, but there was no significant difference between 50% shallot’s water extortion with 200% shallot’s. Theconclusion was shallot’s water extortion had antifungal activity againsts Candida albicans with the best concentration100%, but it was lower than ketoconazole 2%.

STUDY ON NEW COMPLEX COMPOUNDS OF Ti(IV) AND Zr(IV) IN AQUEOUS SOLUTIONS: SYNTHESIS, STABILITY AND APPLICATION IN CLEANER TECHNOLOGIES OF NATURAL LEATHER

2008 ◽  
Vol 7 (3) ◽  
pp. 241-248 ◽  
Author(s):  
Doina Sibiescu ◽  
Ioan Rosca ◽  
Daniel Sutiman ◽  
Marian Crudu ◽  
Adrian Cailean ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Complex Compounds ◽  
Cleaner Technologies

INDICATORS OF THE RAT CARDIORESPIRATORY SYSTEM UNDER THE ACTION OF ACETYLSALICYLIC ACID AND ITS COMPLEX COMPOUNDS WITH METALS

2020 ◽  
Vol 6(72) (2) ◽  
pp. 267-280
Author(s):  
E. N. Chuyan ◽  
I. S. Mironyuk ◽  
M. Yu. Ravaeva ◽  
I. V. Cheretaev ◽  
T. V. Grishina
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Acetylsalicylic Acid ◽  
Biological Effect ◽  
Complex Compounds ◽  
Cardiorespiratory System ◽  
Animal Physiology ◽  
Scientific Equipment ◽  
Pharmaceutical Activity ◽  
Reported Study

The paper researches the effect of cobalt (АСCo2+) and zinc (АСZn2+), nickel (Ni2+) and manganese (Mn2+) acetylsalicylates in doses of 5 and 10 mg/kg on the characteristics of the rats’ cardiorespiratory system. The study was carried out on the basis of the Center for collective use of scientific equipment «Experimental Physiology and Biophysics» of the Department of Human and Animal Physiology and Biophysics of the V. I. Vernadsky Crimean Federal University. The research of the biological effect of the acetylsalicylic acid, АСCo2+, АСZn2+ , АСNi2+, АСMn2+was carried out during their intraperitoneal injection into rats in doses of 5 mg/kg and 10 mg/kg. Simultaneously the following characteristics of all the groups’ animals were registered: heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP) and diastolic blood pressure (DBP). The pulse pressure (PP) was calculated on the basis of the SBP and DBP indices difference. BP, HR and RR of the rats were registered with the help of the system NIBP200A («BiopacSystems, Inc.», USA). The results of the current research allowed to determine that the coordinating compounds of the acetylsalicylic acid with such metals as Co, Zn, Ni2+, Mn2+ not only have more pronounced biological effect in comparison with the acetylsalicylic acid, but demonstrate new properties; the most effect on the cardiorespiratory system was achieved by АСZn2+. Thus, the results of the current research allow us to claim that the salts of the acetylsalicylates, having the metal-complexing in its molecules’ composition, have more pronounced and qualitatively new properties in comparison with the acetylsalicylic acid precursor’s properties; this makes the further search for biological and pharmaceutical activity of these coordinating compounds more perspective, as well as it makes the technology of complexingan inexpensive and highly efficient approach to the creation of new medicines. The reported study was funded by RFBR, project number 20-33-70142

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