scholarly journals AB0104 ARE POLLUTANTS A NEW RISK FACTOR FOR OSTEOARTHRITIS? RESULTS FROM A SYSTEMATIC LITERATURE REVIEW

Author(s):  
Camille Deprouw ◽  
Alice Courties ◽  
Jean-Baptiste Fini ◽  
Marie-Stéphanie Clerget-Froidevaux ◽  
Barbara Demeneix ◽  
...  
2021 ◽  
pp. annrheumdis-2021-221575
Author(s):  
Féline P B Kroon ◽  
Aurélie Najm ◽  
Alessia Alunno ◽  
Jan W Schoones ◽  
Robert B M Landewé ◽  
...  

ObjectivesPerform a systematic literature review (SLR) on risk and prognosis of SARS-CoV-2 infection and vaccination against SARS-CoV-2 in patients with rheumatic and musculoskeletal diseases (RMDs).MethodsLiterature was searched up to 31 May 2021, including (randomised) controlled trials and observational studies with patients with RMD. Pending quality assessment, data extraction was performed and risk of bias (RoB) was assessed. Quality assessment required provision of (1) an appropriate COVID-19 case definition, and (2a) a base incidence (for incidence data) or (2b) a comparator, >10 cases with the outcome and risk estimates minimally adjusted for age, sex and comorbidities (for risk factor data).ResultsOf 5165 records, 208 were included, of which 90 passed quality assessment and data were extracted for incidence (n=42), risk factor (n=42) or vaccination (n=14). Most studies had unclear/high RoB. Generally, patients with RMDs do not face more risk of contracting SARS-CoV-2 (n=26 studies) or worse prognosis of COVID-19 (n=14) than individuals without RMDs. No consistent differences in risk of developing (severe) COVID-19 were found between different RMDs (n=19). Disease activity is associated with worse COVID-19 prognosis (n=2), possibly explaining the increased risk seen for glucocorticoid use (n=13). Rituximab is associated with worse COVID-19 prognosis (n=7) and possibly Janus kinase inhibitors (n=3). Vaccination is generally immunogenic, though antibody responses are lower than in controls. Vaccine immunogenicity is negatively associated with older age, rituximab and mycophenolate.ConclusionThis SLR informed the July 2021 update of the European Alliance of Associations for Rheumatology recommendations for the management of RMDs in the context of SARS-CoV-2.


2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Ivan Švagelj ◽  
Mirta Vučko ◽  
Mato Hrskanović ◽  
Dražen Švagelj

Angiodysplasia is a common type of lesion characterized by malformed submucosal and mucosal blood vessels. Angiodysplasia of the gallbladder is extremely rare, usually an incidental finding, with only two cases reported. Laparoscopic cholecystectomy is a curative treatment for angiodysplasia of the gallbladder. Our report describes a case of angiodysplasia of the gallbladder in a patient who underwent elective laparoscopic cholecystectomy for biliary colic because of gallstones, and a systematic literature review. We surmise that angiodysplasia of the gallbladder could be a risk factor for gallstones in younger female patients.


Author(s):  
Kuntala Boruah ◽  
Manash Kapil Pathak

Child care is one of the most responsible and rewarding jobs of all, but due to several other obligations of parents it is becoming increasingly stressful to ensure their wellbeing and safety throughout the day. Recently adoption of IoT in different folds of child care has been welcomed with open arms. Some of the most addressed areas of applications in child care involve monitoring infants, tracking a school going child, tracking nutrition intake, constant supervision of their health, providing an interactive play mate to the child in the form of toys equipped with Internet of Toys (IoToys) technology etc. Despite all the glorious advantages, there is a tremendous risk factor involved as children are the most vulnerable section of society. In this paper a systematic literature review is conducted and an attempt is made to critically analyse the dual effect of IoT in complementing the traditional process of child care. However IoT healthcare applications for children have not been explored in this paper as a substantial amount of survey literature already exists. The contribution of this paper is to provide an overall insight to the potential researchers about the issues that needed immediate attention and also intended to benefit the decision making of IoT consumers.


2012 ◽  
Vol 7 (1) ◽  
pp. 76 ◽  
Author(s):  
Mark Walterfang ◽  
Yin-Hsiu Chien ◽  
Jackie Imrie ◽  
Derren Rushton ◽  
Danielle Schubiger ◽  
...  

2015 ◽  
Vol 30 (6) ◽  
pp. 756-764 ◽  
Author(s):  
V. Fernandes ◽  
F.L. Osório

AbstractBackgroundPrevious studies indicate a possible association between early emotional trauma (EET) and the development of anxiety disorders (ADs) in adult life. However, no previous studies have compiled the findings of such studies and analyzed their statistical significance. Therefore, the objective of this study was to conduct a systematic literature review and meta-analysis to determine possible associations between EET and three ADs (panic, generalized anxiety, and social anxiety disorders).MethodsA systematic search was conducted in PubMed, PsycInfo, and Scielo with no publication date limitations. A total of 2127 studies were found, 32 studies of which were selected for the systematic review and 13 studies of which were selected for the meta-analysis.ResultsHigh prevalence rates of different EETs were observed among the individuals with ADs (median: 18%–45%). The results of the meta-analysis indicated that individuals with EETs were 1.9- to 3.6-fold more likely to develop ADs compared with a control group of healthy individuals. Emotional traumas were the main risk factor for social anxiety disorder. However, no specific associations were found for the other ADs.ConclusionsEET is a risk factor for ADs, underscoring the importance of preventive measures to combat the development of these disorders. Moreover, the identification of EETs among patients with ADs is essential for implementing remedial measures to minimize the impact and damage arising from this association by decreasing the risk and severity of symptoms and to improve the response rate to treatment of ADs.


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