scholarly journals Paediatric autoimmune neutropaenia

2020 ◽  
Vol 13 (1) ◽  
pp. e229979
Author(s):  
Joshua Michaels ◽  
Anshoo Dhelaria

Neutropaenia is defined as an absolute neutrophil count (ANC) of less than 1500 cells/µL and is often divided into mild (ANC: 1000 to 1500 cells/µL), moderate (ANC: 500 to 1000 cells/µL) and severe (ANC: >500 cells/µL) neutropaenia. Autoimmune neutropaenia is arguably one of the most clinically relevant forms of neutropaenia and is defined by an ANC of <500 cells/µL alongside the confirmed presence of anti-neutrophil antibodies. It is a rare subset of neutropaenia boasting an incidence of just 1 in 100 000 infants and is thought to be caused as a result of a ‘surveillance escape event’ of the immune system. This case report identifies key issues in the diagnosis and monitoring of paediatric patients with recurrent neutropaenia and reviews current literature relating to its management in hospital and community settings.

Author(s):  
Hemant Thakur ◽  
Shirish Vaidya

Abstract Objective: The objective of this study was to describe the antenatal ultrasound appearances of congenital high airway obstruction syndrome (CHAOS), which typically manifests as large echogenic lungs acquiring whole of the thorax and dilatation of the trachea distal to the obstruction and causing intrinsic laryngeal/tracheal obstruction. Case report: A 30-year-old pregnant female with 24 weeks gestation come for routine absolute neutrophil count (ANC) scan. Ultrasonography (USG) was performed, and large echogenic lungs occupying whole of the thoracic cavity compressing the heart in between and causing inversion of the bilateral domes of the diaphragm were found. There was dilatation of the tracheal distal to the lesion and polyhydramnios. Conclusion: The described USG finding of CHAOS may be useful in deciding when to include this entity in the differential diagnosis of enlarged echogenic lungs.


2019 ◽  
Vol 3 (6) ◽  
pp. 466-473
Author(s):  
Jessica L. Cao ◽  
Andrew W. Browne ◽  
Thomas Clifford ◽  
Sumit Sharma ◽  
Vivek Patel

Purpose: Silicone oil (SO) is often used as an intraocular tamponade in repairs of retinal detachments. It may be associated with complications such as cataract, glaucoma, keratopathy, subretinal migration of oil, fibrous epiretinal and sub retinal proliferations, and oil emulsification. The purpose of this report is to describe a rare phenomenon of intraocular silicone oil migration into the cerebral ventricles, which may later be mistaken for intraventricular hemorrhages on neuroimaging. Methods: Case report with literature review. Results: A patient with a history of retinal detachment repair with intraocular SO presented with headaches. Neuroimaging revealed SO migration to the cerebral ventricles. The patient was treated conservatively with symptom management and headaches resolved. Conclusions: We present a case of intraocular SO migration to the cerebral ventricles and review the current literature. We also propose two mechanisms for this phenomenon.


1999 ◽  
Vol 133 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Theresa B. Haddy ◽  
Sohail R. Rana ◽  
Oswaldo Castro

Author(s):  
Christina Georgeades ◽  
Rakel Zarb ◽  
Zoe Lake ◽  
Jacob Wood ◽  
Brian Lewis

2021 ◽  
pp. 153857442110462
Author(s):  
Ahmed A. Sorour ◽  
Levester Kirksey ◽  
Sarah Keller ◽  
Michael S. O’Connor ◽  
Sean P. Lyden

Catastrophic antiphospholipid syndrome (CAPS) is a rare life threatening presentation of antiphospholipid syndrome. Surgery has been proposed as one of the triggering factors for this life threatening entity. There are no detailed published reports in the current literature describing CAPS as a complication after surgery. We report a case of a 21 year old that developed CAPS postoperatively and discuss the multidisciplinary approach for diagnosis and management.


2014 ◽  
Vol 8 ◽  
pp. CMC.S10990 ◽  
Author(s):  
Muhammad Akhtar ◽  
Tariq Bhat ◽  
Mohmad Tantray ◽  
Chris Lafferty ◽  
Saiful Faisal ◽  
...  

As the number of patients having implantable cardioverter defibrillator (ICD) devices is increasing, it is important for the physicians and patients to be aware of situations and conditions that can result in interference with normal functioning of these devices. There are multiple cases of malfunction of ICDs reported in literature and it may be of great significance to have an overview of these incidents for appropriate recognition and future prevention. Here we are reviewing the available literature as well as reporting an interesting case of electromagnetic interference (EMI) resulting from leak of current in pool water causing firing of ICD.


1999 ◽  
Vol 21 (4) ◽  
pp. 341
Author(s):  
D. M. Parham ◽  
P. North ◽  
C. Quiggins ◽  
R. Ready ◽  
C. Stine ◽  
...  

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