Bilateral mammary hibernoma mimicking breast carcinoma: a diagnostic challenge

2021 ◽  
Vol 14 (3) ◽  
pp. e240552
Author(s):  
Royson Dsouza ◽  
Anish Jacob Cherian ◽  
Radha Ananthakrishnan ◽  
Nandakumar Menon
Keyword(s):  
Postmenopausal Woman ◽  
Clinical Presentation ◽  
Surgical Excision ◽  
Age Group ◽  
Common Condition ◽  
Diagnostic Challenge ◽  
The Core ◽  
Complete Surgical Excision ◽  
History Of ◽  
Breast Lumps

We describe a 68-year-old postmenopausal woman who presented with a history of rapidly enlarging lumps in both breasts. Though the breast lumps appeared suspicious on ultrasonography, the core biopsy was reported to be benign. In view of the clinical and radiological suspicion of malignancy, she underwent a diagnostic excision of both the lumps, the histopathology was consistent with mammary hibernoma. To the best of the authors’ knowledge, this is the first report of a bilateral mammary hibernoma in an elderly postmenopausal woman. Given the clinical presentation, it is important to differentiate mammary hibernoma from carcinoma breast, which is a more common condition in this age group. However, preoperative diagnosis is challenging in view of the lack of definitive radiological and histological features. Although benign, hibernoma may have a propensity for local recurrence and, therefore, complete surgical excision remains the mainstay of treatment.

INTRAOSSEOUS ANGIOLIPOMA OF THE CRANIUM

Neurosurgery ◽  
2009 ◽  
Vol 64 (1) ◽  
pp. E189-E190 ◽  
Author(s):  
Kenny Yu ◽  
James Van Dellen ◽  
Philip Idaewor ◽  
Federico Roncaroli
Keyword(s):  
Clinical Presentation ◽  
Subcutaneous Tissue ◽  
Rare Condition ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Complete Surgical Excision ◽  
History Of ◽  
Titanium Cranioplasty ◽  
Intraosseous Lesion ◽  
Slow Growing

Abstract OBJECTIVE We describe an intraosseous angiolipoma of the cranium and discuss the outcome. Angiolipomas are benign tumors that consist of mature adipose tissue and abnormal vessels. They occur predominantly in the subcutaneous tissue of the trunk and upper limbs. Only 4 examples of intraosseous angiolipomas have been reported in the literature, all of which involved the mandible and ribs. CLINICAL PRESENTATION A 39-year-old man presented with a right parietal swelling. The patient initially refused surgery; thus it was possible to follow this case for 11 years, allowing us to evaluate the natural history of this rare condition. INTERVENTION Complete surgical excision of the intraosseous lesion was achieved with a titanium cranioplasty performed at intervals. Fifteen months after surgery, no recurrence was seen. CONCLUSION This is the first known report of intraosseous angiolipoma of the cranium. Angiolipomas are rare, benign, slow-growing tumors with an excellent prognosis. On preoperative neuroimaging, they may mimic intraosseous angiomas, lipomas, or intraosseous meningiomas. Total resection is curative.

scholarly journals Pleomorphic adenoma of dorsum of the nose: a rare occurrence

2020 ◽  
Vol 6 (10) ◽  
pp. 1919
Author(s):  
Rajiv Kumar Jain ◽  
Chultim D. Bhutia ◽  
Deepak Kumar Gupta ◽  
Ashvanee Kumar Chaudhary ◽  
Gagan Rangari ◽  
...  
Keyword(s):  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Histological Evaluation ◽  
Prior History ◽  
Salivary Gland Tumours ◽  
Complete Surgical Excision ◽  
Complete Surgical Resection ◽  
Long Term Follow Up ◽  
History Of ◽  
Benign Salivary Gland Tumours

<p class="abstract">Pleomorphic adenoma are common benign salivary gland tumours, which are found in majority in major salivary glands such as parotids and submandibular glands. However, Pleomorphic adenoma to originate from dorsum of the nose is a rare entity. In rare cases, it can be found in unusual sites such as upper aero digestive tracts, palate and lacrimal glands. Complete surgical resection is the treatment of choice. Though, the evolution to malignancy and recurrence is not usually encountered, still a long-term follow-up is recommended. Here, we report a 53 year old female , complained of swelling in the left side of dorsum of nose for 10 years with a feeling of heaviness over the left side of face and difficulty in vision on the side of swelling due to the enlarged size of the swelling which gave a feeling of vision disruption , also had a prior history of  incision and drainage 4 years ,done elsewhere. On clinical examination, nodular mass was palpated on left side dorsum of nose which was freely mobile, and Skin over the swelling had blackish pigmentation. Anterior rhinoscopy revealed no abnormalities. Complete surgical excision via a lateral rhinotomy incision was performed. Cytological and histological evaluation revealed the presence of pleomorphic adenoma. We observed a decent cosmetic outcome with no evidence of recurrence.</p>

Traumatic ulcers with a hidden cause: A case report

Dental Update ◽  
2021 ◽  
Vol 48 (2) ◽  
pp. 141-143
Author(s):  
Pavneet Chana ◽  
Daniela Ion
Keyword(s):  
Case Report ◽  
Oral Mucosa ◽  
Secondary Care ◽  
Clinical Relevance ◽  
Clinical Presentation ◽  
Common Condition ◽  
Oral Ulceration ◽  
History Of

Oral ulceration is a common condition that can affect the oral mucosa, and patients often present in both primary and secondary care. There are a number of causes of oral ulceration, ranging from trauma to malignancy. The cause of the oral ulceration can be difficult to establish, especially when the history and investigations do not support an obvious cause. We report a case of a 19-year-old male who presented with a 2-month history of worsening oral ulceration. Despite further questioning and investigations, the cause of the oral ulceration remained elusive. CPD/Clinical Relevance: To understand the clinical presentation and causes of oral ulceration.

Conjunctival Stromal Tumor: Report of 2 New Cases and Review of the Literature

2020 ◽  
pp. 106689692094578
Author(s):  
Jonathan Lam ◽  
Andrea Ang ◽  
Tersia Vermeulen ◽  
Nima Mesbah Ardakani
Keyword(s):  
Surgical Excision ◽  
Stromal Tumor ◽  
Biological Behavior ◽  
Bulbar Conjunctiva ◽  
Age Group ◽  
Normal Pattern ◽  
Complete Surgical Excision ◽  
Tender Mass ◽  
Collagenous Stroma ◽  
Slow Growing

Conjunctival stromal tumor (COST) is an emerging entity with only a limited number of cases reported in the literature. In this report, we describe 2 additional cases, review the accumulative clinical and histopathological features and expand on the immunophenotypic property of this entity. COST appears to have a sporadic presentation, affecting both sexes and patients of variable ethnicity and age group and predominantly occurring on the bulbar conjunctiva as a slow-growing asymptomatic or slightly tender mass-like lesion. Histopathologically, COST is characterized by singly dispersed spindle to round cells, often with some degree of degenerative nuclear atypia, within a myxomatous to collagenous stroma. Lesional cells are characteristically positive for CD34 and vimentin, negative for S100, SOX10 and STAT6 and show a normal pattern of staining with RB1 by immunohistochemistry. The reported cases to date have shown an indolent biological behavior, reliably treated by a complete surgical excision.

A clinico-aetiological and ultrasonographic study of Peyronie's disease

Sexual Health ◽  
2006 ◽  
Vol 3 (2) ◽  
pp. 113 ◽  
Author(s):  
Bhushan Kumar ◽  
Tarun Narang ◽  
Somesh Gupta ◽  
Madhu Gulati
Keyword(s):  
Clinical Presentation ◽  
Clinical Symptoms ◽  
Tunica Albuginea ◽  
Connective Tissue Disorder ◽  
Peyronie’S Disease ◽  
Penile Curvature ◽  
Age Group ◽  
History Of ◽  
Peyronie's Disease ◽  
Symptoms And Signs

Background: Peyronie’s disease is a localised connective tissue disorder that involves the tunica albuginea of the penis. Although long recognised as an important clinical entity of the male genitalia, the aetiology of this disease has remained poorly understood. Methods: The epidemiology and clinical presentation of Peyronie’s disease during a 10-year period was evaluated. Results: Forty-two men with Peyronie’s disease from Chandigarh, India were reviewed retrospectively. The prevalence of Peyronie’s patients was 1.97/1000 patients. Their ages ranged from 23 to 70 years. Most of them presented during the early phase of the disease. The most common presenting complaint was penile curvature in 34 (80.95%) followed by pain on erection in 28 (66.66%). History of penile trauma was revealed by four (9.52%) patients. Among the risk factors, hypercholesterolemia (60%), hypertension (33.3%) and asymptomatic hyperuricemia (28.34%) were the most common. Twenty-two patients with Peyronie’s disease were studied by ultrasonography. Ultrasonogram was more accurate than clinical assessment in delineating the extent of lesions. In one-third of the patients, sonography demonstrated the plaques to be more extensive than had been detected by clinical examination. Conclusions: The clinical symptoms and signs in our study were, in general, similar to those found in the previous studies. Higher incidence of hypertension and diabetes in patients with Peyronie’s disease may also be to an extent due to patients being in an older age group.

scholarly journals Diagnosis and management of a case of retroperitoneal eosinophilic sclerosing fibroplasia in a cat

2019 ◽  
Vol 5 (2) ◽  
pp. 205511691986717
Author(s):  
Maureen E Thieme ◽  
Anastasia M Olsen ◽  
Andrew D Woolcock ◽  
Margaret A Miller ◽  
Micha C Simons
Keyword(s):  
Abdominal Mass ◽  
Clinical Signs ◽  
Surgical Excision ◽  
Clinical Findings ◽  
Peripheral Eosinophilia ◽  
Aerobic Culture ◽  
Complete Surgical Excision ◽  
History Of ◽  
Amoxicillin Clavulanic Acid ◽  
The Masses

Case summary A 4-year-old neutered male cat was presented with a 2-month history of intermittent constipation that progressed to obstipation. Primary clinical findings included a large, multi lobulated mass in the caudodorsal abdomen, peripheral eosinophilia and hyperglobulinemia. Abdominal imaging revealed a multilobulated, cavitated mass in the sublumbar region. Exploratory celiotomy revealed multiple firm masses in the sublumbar retroperitoneal space causing ventral displacement and compression of the descending colon with extension of the masses into the pelvic canal. Histopathology was consistent with feline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF). Aerobic culture was positive for Staphylococcus aureus. The cat was treated with prednisolone (2 mg/kg PO q24h), lactulose (0.5 g/kg PO q8h), amoxicillin/clavulanic acid (62.5 mg/cat PO q12h for 1 month) and fenbendazole (50 mg/kg PO q24h for 5 days). Six months postoperatively, the cat had no recurrence of clinical signs. Repeat evaluation and imaging at day 732 postoperatively revealed marked improvement of the abdominal mass, resolution of peripheral eosinophilia and no clinical signs with continued prednisolone therapy (0.5 mg/kg PO q24h). Relevance and novel information This is a report of a primary extramural FGESF lesion, and the first description of characteristics of FGESF on CT. Previous evidence suggests that the most favorable outcomes require immunosuppressive therapy and complete surgical excision; however, this case demonstrates a favorable outcome with medical management alone.

scholarly journals Morel-Lavallée lesion in a ‘non-traumatic’ thigh: a diagnostic challenge!

2019 ◽  
Vol 18 (1) ◽  
pp. 145-148
Author(s):  
Devesh Sanjeev Ballal ◽  
Balaji Jayasankar ◽  
Gabriel Rodrigues ◽  
Ranjini Kudva
Keyword(s):  
Soft Tissue ◽  
Medical Science ◽  
Surgical Excision ◽  
Diagnostic Challenge ◽  
Soft Tissue Neoplasm ◽  
Diagnostic Dilemma ◽  
Degloving Injury ◽  
Closed Degloving Injury ◽  
History Of ◽  
Closed Degloving

Background: Morel-Lavallée Lesion (MLL) or Morel-Lavallée Seroma (MLS) is a posttraumatic seroma that occurs following a closed degloving injury. It is very important for trauma surgeons to be aware of this relatively rarely reported entity as early diagnosis increases the likelihood of successful management. Case report: We present a patient, wherein the patient had no history of trivial trauma and presented with a gradually growing swelling of left thigh, that was clinically and radiologically diagnosed as a soft tissue neoplasm, successfully managed by surgical excision and were reported to be a MLS. The clinical diagnostic dilemma was solved by the histopathologist! Conclusion: A differential diagnosis of MLL should be kept in mind in patients presenting with soft tissue swellings. Bangladesh Journal of Medical Science Vol.18(1) 2019 p.145-148

scholarly journals Extraosseous Intra-Articular Osteochondroma

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Pragash Mohanen ◽  
Kumaresan Palania Pillai ◽  
Kanagasabai Rangasamy
Keyword(s):  
Surgical Excision ◽  
Left Knee ◽  
Bone Lesions ◽  
Excision Biopsy ◽  
Anatomic Site ◽  
Anterior Portion ◽  
Tissue Mass ◽  
Complete Surgical Excision ◽  
Biological Potential ◽  
History Of

Background. Conventional osteochondromas are common bone lesions developing in the metaphyseal region of growing skeleton. Marginal excision is the treatment of choice for such tumours. Extraosseous cartilaginous tumours are rare and their biological potential is poorly characterized.Case Presentation. A-52-year old woman presented with 3-year history of fullness and dull pain and inability to flex her left knee, sit cross-legged, or squat. Clinical and imaging studies revealed a nodular mineralised mass in the anterior portion of the knee displacing the patellar tendon laterally. Excision biopsy confirmed the diagnosis of extraosseous osteochondroma-like soft tissue mass. There is no recurrence at two-year followup.Conclusion. An integrated clinicopathological diagnosis helps to clarify the nature of extraosseous cartilaginous tumour that can arise at an unusual anatomic site. Complete surgical excision is the treatment of choice.

scholarly journals Giant Endometrial Polyp in a Postmenopausal Woman without Hormone/Drug Use and Vaginal Bleeding

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Betül Ünal ◽  
Selen Doğan ◽  
Fatma Şeyda Karaveli ◽  
Tayup Şimşek ◽  
Gülgün Erdoğan ◽  
...  
Keyword(s):  
Postmenopausal Woman ◽  
Drug Use ◽  
Vaginal Bleeding ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Uterine Cavity ◽  
Endometrial Polyp ◽  
Lower Back ◽  
History Of

The objective of this study is to determine and discuss the causes of a giant endometrial polyp in a postmenopausal woman without hormone/drug use and to submit interesting clinical presentation. Here we report a seventy-year-old female patient who was admitted to our hospital with lower back pain. There were no other complaints from her. Physical examination was normal. For further examination, computed tomography was performed and a heterogeneous mass, with a diameter of 10×9 centimeters, was detected in the uterine cavity. Hysterectomy because of suspected endometrial cancer was performed. Histopathological examination showed us a giant endometrial polyp with edematous and focal fibrotic stroma, large thick walled blood vessels between normal sized and cystically dilated endometrial glands. To the best of our knowledge, this is the first report of a giant endometrial polyp which is unrelated to use of drugs such as tamoxifen and raloxifene; however, based on the history of the patient it may be associated with long-term consumption of thyme, which is a kind of phytoestrogen.

scholarly journals Colossal Malignant Nonteratoid Medulloepithelioma of the Eye with Unusual Metastases: The Natural History

2010 ◽  
Vol 1 (1) ◽  
pp. 39-42 ◽  
Author(s):  
Qureshi Sajid
Keyword(s):  
Natural History ◽  
Regional Lymph Node ◽  
Postoperative Radiotherapy ◽  
Distant Metastases ◽  
Surgical Excision ◽  
Facial Soft Tissue ◽  
Cervical Lymph Nodes ◽  
Complete Surgical Excision ◽  
Aggressive Surgical Approach ◽  
History Of

Abstract Background Medulloepithelioma is rare intraocular tumor seen predominantly in children, and arising mainly from undifferentiated nonpigmented epithelium of the ciliary body. Methods We present a typical neglected case of malignant nonteratoid medulloepithelioma of the eye with extensive metastases to the facial soft tissue parotid and cervical lymph nodes. Results An aggressive surgical approach with orbital exenteration and comprehensive disease clearance with total parotidectomy and neck dissection augmented by postoperative radiotherapy was utilized after initial unsuccessful chemotherapy. Conclusions The present case highlights the natural history of untreated medulloepithelioma of the eye. Colossal growth at the primary site with extensive regional lymph node metastases develops without distant metastases. Complete surgical excision supplemented with postoperative radiotherapy should be considered even in the setting of advanced locoregional disease.

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