scholarly journals Progression of myopia in children and teenagers: a nationwide longitudinal study

2021 ◽  
pp. bjophthalmol-2020-318256
Author(s):  
Dorian Tricard ◽  
Simon Marillet ◽  
Pierre Ingrand ◽  
Mark A Bullimore ◽  
Rupert R A Bourne ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Longitudinal Study ◽  
Prospective Study ◽  
Large Scale ◽  
Age Groups ◽  
Spherical Equivalent ◽  
Large Prospective Study ◽  
Myopia Progression ◽  
Gender And Age ◽  
A Prospective Study

BackgroundData on myopia prevalence and progression in European children are sparse. The aim of this work was to evaluate the progression of myopia in children and teenagers in a large prospective study.MethodsA prospective study involving a nationwide cohort. Myopia was defined as a spherical equivalent (SE) of ≤ –0.50 diopters (D). Data on refractive error, gender and age were collected in 696 optical centres in France between 2013 and 2019, including 136 333 children (4–17 years old) in the analysis.Progression of myopia was assessed between the first visit and the last visit over up to 6.5 years.ResultsMean age was 11.3±3.8 years (55.0% of female). The proportion of children progressing more than –0.50 D per year was higher in age groups 7–9 years and 10–12 years and in children with SE ≤ –4.00 D at first visit, representing 33.1%, 29.4% and 30.0% of these groups, respectively. In multivariate analysis, progression during the first 11–24 months was higher in the 7–9 and 10–12 age groups (–0.43 D and –0.42 D, respectively), for higher SE at baseline (at least –0.33 D for SE ≤ –1 D) and for girls (–0.35 D).ConclusionThis is the first French epidemiological study to investigate myopia progression in a large-scale cohort of children. Sex, age groups and myopia severity are associated with differing rates of progression.

scholarly journals Study of correlation of ultrasonography with surgical evaluation of adnexal masses: a prospective study

2018 ◽  
Vol 7 (10) ◽  
pp. 4218
Author(s):  
Urmila Tripathi ◽  
Geetanjali Munda
Keyword(s):  
Prospective Study ◽  
Clinical Symptoms ◽  
Histopathological Examination ◽  
Abdominal Mass ◽  
Age Groups ◽  
Serous Cystadenoma ◽  
Ovarian Tumors ◽  
Adnexal Masses ◽  
Malignant Changes ◽  
A Prospective Study

Background: Adnexal masses are one of the most common pathologies among women of all age groups. Ovarian tumors, alone, represent two thirds of these cases. Malignant ovarian tumors are the fourth most common cause of death in women. Accurate diagnosis is required foremost for proper treatment and management of the patients.Methods: A prospective study done on 100 patients with adnexal masses presenting to Department of Obstetrics and Gynecology at Kamla Raja Hospital, G.R.M.C, Gwalior from February 2015 to August 2016. Firstly, the cases were studied by ultrasonography then intraoperatively and simultaneous sampling for HPE done. The study included women with clinical symptoms of pain abdomen/ discomfort, bleeding per vaginum, abdominal mass was subjected to ultrasonography, diagnosed with adnexal mass. 100 indicated patients were taken for surgery and intraoperative tissue and fluid samples were taken and sent for HPE.Results: No discordance found regarding laterality of adnexal masses between ultrasonographical findings and surgical findings. 69% cases were devoid of any septation/locules/nodules. Most common pathology found to be ectopic pregnancy. Most common benign ovarian mass encountered was serous cystadenoma (31.1%) and malignant mass was serous adenocarcinoma (12.7%). Apart from 13 malignant adnexal masses, 2 adnexal masses had malignant changes found on histopathological examination. 11 cases were found to be of advanced stage on surgical findings, which then confirmed by HPE.Conclusions: There is positive correlation between ultrasonographical and surgerical evaluation of adnexal masses. Correlation of the lesion’s location and appearance at imaging with the surgical findings will aid in the detection of potential pathology reporting errors.

scholarly journals Patient satisfaction and objective outcome assessment following mid-urethral sling procedures in women with stress urinary incontinence: A prospective study

2019 ◽  
Author(s):  
Zinat Ghanbari ◽  
Seyedeh Belin Tavakoly Sany ◽  
Maryam Hajhashemi ◽  
Nahid Radnia ◽  
Arezoo Orooji ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Urinary Incontinence ◽  
Patient Satisfaction ◽  
Stress Urinary Incontinence ◽  
Prospective Study ◽  
A Prospective Study ◽  
Cure Rates ◽  
Effective Procedures ◽  
Objective Cure

Abstract Background Mid-urethral sling (MUS) operations are currently a recognized as the most popular and effective procedures for the surgical treatment of stress urinary incontinence (SUI) among women population. However, data reporting a long-term outcome is still equivocal, and thus, the data available are limited. This study aims to examine the efficacy of MUS operations after implantation for the treatment of women SUI during 3-years follow up. Method A prospective study was conducted in referral centers in the Tehran University of Medical Science, Emam Khomeini Hospital, Iran. 105 patients with urodynamically proven pure SUI or mix incontinence treated by MUS surgeries (TOT-TVT) were included. Patients with history of prior anti-incontinence surgery and abdominal radical pelvic surgery were excluded. Data regarding objective cure rates, subjective outcomes (Urogenital Distress Inventory Questionnaire–Short Form, Surgical Satisfaction Questionnaire) were collected during follow-up. We analyzed the preoperative parameters by univariate and multivariate analysis was conducted to investigate outcomes. Results One hundred five women had MUS implantation. At 4-years follow-up, 101 women (95%) were available for the assessment. We find evidence of significant improvement in urinary symptoms, objective cure rates and patient satisfaction after operation. At 3-years follow up, 80 of 101 women (82.17%) indicated themselves cured. Similarly, at 3-years evaluation, 83 of 101 women (82.17%) were satisfied or very satisfied, not showing visible urine leakage; and a state that did not need interval surgery. The multivariate analysis of the preoperative parameters revealed that age, VD, absences of urgency symptoms were the parameters related independently to the surgical success and patient’s satisfaction and Qmax was well associated with postoperative voiding dysfunction (PVD). Conclusion The 4-years findings of this study suggest that MUS surgeries are an effective procedures for the treatment of SUI.

scholarly journals Swearing in informal spoken English: 1990s–2010s

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Robbie Love
Keyword(s):  
Large Scale ◽  
Economic Status ◽  
Age Groups ◽  
British English ◽  
Spoken English ◽  
Gender And Age ◽  
The Social ◽  
Social Distribution ◽  
British National Corpus ◽  
National Corpus

Abstract This paper investigates changes in swearing usage in informal speech using large-scale corpus data, comparing the occurrence and social distribution of swear words in two corpora of informal spoken British English: the demographically-sampled part of the Spoken British National Corpus 1994 (BNC1994) and the Spoken British National Corpus 2014 (BNC2014); the compilation of the latter has facilitated large-scale, diachronic analyses of authentic spoken data on a scale which has, until now, not been possible. A form and frequency analysis of a set of 16 ‘pure’ swear word lemma forms is presented. The findings reveal that swearing occurrence is significantly lower in the Spoken BNC2014 but still within a comparable range to previous studies. Furthermore, FUCK is found to overtake BLOODY as the most popular swear word lemma. Finally, the social distribution of swearing across gender and age groups generally supports the findings of previous research: males still swear more than females, and swearing still peaks in the twenties and declines thereafter. However, the distribution of swearing according to socio-economic status is found to be more complex than expected in the 2010s and requires further investigation. This paper also reflects on some of the methodological challenges associated with making comparisons between the two corpora.

scholarly journals A prospective study of intestinal obstruction in paediatric age group

2017 ◽  
Vol 4 (6) ◽  
pp. 1979
Author(s):  
Amul Bhedi ◽  
Miten Prajapati ◽  
Arnab Sarkar
Keyword(s):  
Intestinal Obstruction ◽  
Prospective Study ◽  
Hypertrophic Pyloric Stenosis ◽  
Age Groups ◽  
Total Mortality ◽  
Infants And Children ◽  
Age Group ◽  
Female Ratio ◽  
Paediatric Age ◽  
A Prospective Study

Background: Intestinal obstruction can occur at any age in the paediatric population1-4. Bowel obstruction in children differs from that in adults in terms of etiology, presentation and even the management. The aim of the study was to find out various etiologies, clinical features, outcome and mortality of paediatric age groups with intestinal obstruction and their relation to age and sex distribution.Methods: This is a prospective study of 50 cases of paediatric age group with signs and symptoms of intestinal obstruction which were admitted in Sir Sayajirao Gaekwad Hospital, Vadodara, India during period of December 2004 to November 2006. Surgical intervention was carried out where indicated otherwise patients were managed conservatively. Data was analysed in SPSS version 10 statistical software for percentage and frequencies.Results: Total 50 patients were included in the study. Among these 30 were males and 20 were females with M: F ratio of 3:2. Majority of them were 25 neonates of age group of 1-7 days (50%), followed by 7 infants of 1 months- 1 years (14%) and 18 children aged 1 years-12 years (36%).  Out of 50 patients, 41 (82%) patients had congenital causes in which 21(42%) patients had imperforate anus followed by Hirschprung’s disease in 8(16%), Meckel’s diverticulum in 6(12%), jejunal atresia in 4(8%), hypertrophic pyloric stenosis in 2 patients (4%) and 9(18%) patients had acquired causes in which intussusception was in 5(10%) patients, abdominal tuberculosis in 2(4%) and gangrenous appendix in 2(4%) patients. Total mortality was 6 out of 25 neonates and there were no mortality in infants and children groups.Conclusions: Majority of patients were neonates than infants and children with slight male preponderance with male: female ratio of 3:2. Congenital causes of intestinal obstruction were more common (82%) than the acquired causes (18%). Postoperative septicaemia was more common and overall mortality was exclusively in neonates.

scholarly journals Intraocular pressure and circumpapillary retinal nerve fibre layer thickness in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA): distributions and associations

2020 ◽  
pp. bjophthalmol-2020-316499
Author(s):  
Paul McCann ◽  
Ruth Hogg ◽  
David M Wright ◽  
Usha Chakravarthy ◽  
Tunde Peto ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Intraocular Pressure ◽  
Longitudinal Study ◽  
Northern Ireland ◽  
Refractive Error ◽  
Retinal Nerve Fibre Layer ◽  
Spherical Equivalent ◽  
The Mean ◽  
Male Sex ◽  
Nerve Fibre Layer

AimsTo describe the distributions of and associations with intraocular pressure (IOP) and circumpapillary retinal nerve fibre layer (cRNFL) thickness in a population-based study.MethodsNorthern Ireland Cohort for the Longitudinal Study of Ageing participants underwent a computer-assisted personal interview, a self-completion questionnaire and a health assessment (HA). At the HA, participants underwent IOP measurement using Ocular Response Analyser and spectral-domain optical coherence tomography with Heidelberg Spectralis. Participants also underwent a range of anthropometric, ophthalmic, cardiovascular, cognition and blood tests. Participants who attended the HA and had a vertical cup-to-disc ratio (VCDR) measurement in at least one eye were eligible for the study. Participants without any IOP or cRNFL measurements were excluded from the respective analyses.ResultsThere were 3221 participants eligible for this study (5753 eyes included in the IOP analysis and 5461 eyes included in the cRNFL analysis). The mean (SD) Goldmann correlated IOP (IOPg) was 15.39 mm Hg (3.55 mm Hg). The mean (SD) average global cRNFL thickness was 94.39 µm (11.18 µm). Increased IOPg was associated with increased age, male sex, hypertension, refractive error (myopic decrease in spherical equivalent) and increased corneal resistance factor, while beta-blocker drug use was associated with lower IOPg in the fully adjusted multivariate analysis. Thinner average global cRNFL was associated with Alzheimer’s disease in the age-adjusted and sex-adjusted model. In the fully adjusted multivariate analysis, increased age, male sex, left eyes, hypertension, increased VCDR, refractive error (myopic decrease in spherical equivalent) and increased IOPg were associated with thinner average global cRNFL, while Parkinson’s disease and current (vs never) smoking status were associated with thicker average global cRNFL.ConclusionsIncreased IOP and reduced cRNFL were associated with increased age, myopic refractive error, male sex and hypertension. Alzheimer’s disease was associated with thinner average global cRNFL, while Parkinson’s disease was associated with thicker average global cRNFL.

scholarly journals Accuracy of weight estimation methods in adults, adolescents and children: a prospective study

2020 ◽  
pp. emermed-2020-209581
Author(s):  
Giles N Cattermole ◽  
Appolinaire Manirafasha
Keyword(s):  
Prospective Study ◽  
Age Groups ◽  
Primary Outcome Measure ◽  
Estimation Methods ◽  
Weight Estimation ◽  
Actual Weight ◽  
Arm Circumference ◽  
Outpatient Departments ◽  
Length Data ◽  
A Prospective Study

IntroductionWeight estimation of both adult and paediatric patients is often necessary in emergency or low-resource settings when it is not possible to weigh the patient. There are many methods for paediatric weight estimation, but no standard methods for adults. PAWPER and Mercy tapes are used in children, but have not been assessed in adults. The primary aim of this study was to assess weight estimation methods in patients of all ages.MethodsPatients were prospectively recruited from emergency and outpatient departments in Kigali, Rwanda. Participants (or guardians) were asked to estimate weight. Investigators collected weight, height, mid-arm circumference (MAC) and humeral-length data. In all participants, estimates of weight were calculated from height and MAC (PAWPER methods), MAC and humeral length (Mercy method). In children, Broselow measurements and age-based formulae were also used. The primary outcome measure was the proportion of estimates within 20% of actual weight (p20).ResultsWe recruited 947 participants: 307 children, 309 adolescents and 331 adults. For p20, the best methods were: in children, guardian estimate (90.2%) and PAWPER XL-MAC (89.3%); in adolescents, PAWPER XL-MAC (91.3%) and guardian estimate (90.9%); in adults, participant estimate (98.5%) and PAWPER XL-MAC (83.7%). In all age groups, there was a trend of decreasing weight estimation with increasing actual weight.ConclusionThis prospective study of weight estimation methods across all age groups is the first adult study of PAWPER and Mercy methods. In children, age-based rules performed poorly. In patients of all ages, the PAWPER XL-MAC and guardian/participant estimates of weight were the most reliable and we would recommend their use in this setting.

scholarly journals Gender, Age and Subjective Well-Being: Towards Personalized Persuasive Health Interventions

Information ◽  
2019 ◽  
Vol 10 (10) ◽  
pp. 301
Author(s):  
Aisha Muhammad Abdullahi ◽  
Rita Orji ◽  
Abdullahi Abubakar Kawu
Keyword(s):  
Structural Equation ◽  
Large Scale ◽  
Satisfaction With Life ◽  
Age Groups ◽  
Well Being ◽  
Design Guidelines ◽  
Health Interventions ◽  
Subjective Well Being ◽  
Gender And Age ◽  
Cognitive Dimensions

(1) Background: Subjective well-being (SWB) is an individual’s judgment about their overall well-being. Research has shown that high subjective well-being contributes to overall health. SWB consists of both Affective and Cognitive dimensions. Existing studies on SWB are limited in two major ways: first, they focused mainly on the Affective dimension. Second, most existing studies are focused on individuals from the Western and Asian nations; (2) Methods: To resolve these weaknesses and contribute to research on personalizing persuasive health interventions to promote SWB, we conducted a large-scale study of 732 participants from Nigeria to investigate what factors affect their SWB using both the Affective and Cognitive dimensions and how distinct SWB components relates to different gender and age group. We employed the Structural Equation Model (SEM) and Confirmatory Factor Analysis (CFA) to develop models showing how gender and age relate to the distinct components of SWB; (3) Results: Our study reveals significant differences between gender and age groups. Males are more associated with social well-being and satisfaction with life components while females are more associated with emotional well-being. As regards age, younger adults (under 24) are more associated with social well-being and happiness while older adults (over 65) are more associated with psychological well-being, emotional well-being, and satisfaction with life. (4) Conclusions: The results could inform designers of the appropriate SWB components to target when personalizing persuasive health interventions to promote overall well-being for people belonging to various gender and age groups. We offer design guidelines for tailoring persuasive intervention to increase SWB based on an individual’s age and gender group. Finally, we map SWB components to possible persuasive technology design strategies that can be employed to implement them in persuasive interventions design.

Sign in / Sign up

Export Citation Format

Share Document