scholarly journals Lockdown and non-COVID-19 deaths: cause-specific mortality during the first wave of the 2020 pandemic in Norway: a population-based register study

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e050525
Author(s):  
Guttorm Raknes ◽  
Marianne Sørlie Strøm ◽  
Gerhard Sulo ◽  
Simon Øverland ◽  
Mathieu Roelants ◽  
...  

ObjectiveTo explore the potential impact of the first wave of COVID-19 pandemic on all cause and cause-specific mortality in Norway.DesignPopulation-based register study.SettingThe Norwegian cause of Death Registry and the National Population Register of Norway.ParticipantsAll recorded deaths in Norway from March to May from 2010 to 2020.Main outcome measuresRate (per 100 000) of all-cause mortality and causes of death in the European Shortlist for Causes of Death from March to May 2020. The rates were age standardised and adjusted to a 100% register coverage and compared with a 95% prediction interval (PI) from linear regression based on corresponding rates for 2010–2019.Results113 710 deaths were included, of which 10 226 were from 2020. We did not observe any deviation from predicted total mortality. There were fewer than predicted deaths from chronic lower respiratory diseases excluding asthma (11.4, 95% PI 11.8 to 15.2) and from other non-ischaemic, non-rheumatic heart diseases (13.9, 95% PI 14.5 to 20.2). The death rates were higher than predicted for Alzheimer’s disease (7.3, 95% PI 5.5 to 7.3) and diabetes mellitus (4.1, 95% PI 2.1 to 3.4).ConclusionsThere was no significant difference in the frequency of the major causes of death in the first wave of the 2020 COVID-19 pandemic in Norway compared with corresponding periods 2010–2019. There was an increase in diabetes mellitus and Alzheimer’s deaths. Reduced mortality due to some heart and lung conditions may be linked to infection control measures.

2021 ◽  
Author(s):  
Guttorm Raknes ◽  
Marianne Sørlie Strøm ◽  
Gerhard Sulo ◽  
Simon Øverland ◽  
Mathieu Roelants ◽  
...  

ABSTRACTObjectiveTo explore the potential impact of the first wave of COVID-19 pandemic on all cause and cause-specific mortality in Norway.DesignPopulation based register study.SettingThe Norwegian cause of Death Registry and the National Population Register of Norway.ParticipantsAll recorded deaths in Norway during March to May from 2010 to 2020.Main outcome measuresRate (per 100 000) of all-cause mortality and causes of death in the EU Shortlist for Causes of Death March to May 2020. The rates were age-standardised and adjusted to a 100% register coverage and compared with a 95% prediction interval (PI) based on corresponding rates for 2010-2019.Results113 710 deaths were included, of which 10 226 from 2020. We did not observe any deviation from predicted total mortality. There were fewer than predicted deaths from chronic lower respiratory diseases excluding asthma (11.4, 95% PI 11.8 to 15.2) and from other non-ischemic, non-rheumatic heart diseases (13.9, 95% PI 14.5 to 20.2). The death rates were higher than predicted for Alzheimer’s disease (7.3, 95% PI 5.5 to 7.3) and diabetes mellitus (4.1, 95% PI 2.1 to 3.4).ConclusionsThere was no significant difference in the frequency of the major causes of death in the first wave of the 2020 COVID-19 pandemic in Norway. An increase in diabetes mellitus deaths and reduced mortality due to some heart and lung conditions may be linked to infection control measures.


BMJ Open ◽  
2013 ◽  
Vol 3 (4) ◽  
pp. e002395 ◽  
Author(s):  
Maarit Venermo ◽  
Kristiina Manderbacka ◽  
Tuija Ikonen ◽  
Ilmo Keskimäki ◽  
Klas Winell ◽  
...  

2019 ◽  
Vol 43 (3) ◽  
pp. 319 ◽  
Author(s):  
Sen Li ◽  
Jiaxin Wang ◽  
Biao Zhang ◽  
Xinyi Li ◽  
Yuan Liu

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e19056-e19056
Author(s):  
Nicole H. Dalal ◽  
Graca Dores ◽  
Rochelle E. Curtis ◽  
Martha S. Linet ◽  
Lindsay M. Morton

e19056 Background: LPL and WM are rare, indolent mature B-cell lymphomas. While recent studies reveal improving survival after LPL/WM, cause-specific mortality has not been comprehensively studied. Methods: We identified 6659 adults with first primary LPL (n = 2866) or WM (n = 3793) within 17 US population-based cancer registries from 2000 to 2015. Patients were followed for vital status (mean follow-up = 5.07 years), and causes of death were determined from death certificates. Standardized mortality ratios (SMRs) estimated relative risk of death compared to the general population. We estimated cumulative mortality and absolute excess risk (AER) per 10,000 person-years. Results: We observed 2826 deaths overall, of which 43%, 13%, and 42% were due to lymphoma, cancers excluding lymphoma, and non-malignant causes, respectively. There was a 20% higher risk of death due to non-malignant causes compared to the general population (n = 1194, SMR = 1.2, 95% confidence interval [CI] = 1.1 to 1.2). The most common non-malignant causes included infectious (n = 162, SMR = 1.8, 95% CI = 1.5 to 2.1, AER = 21.0), respiratory (n = 131, SMR = 1.2, 95% CI = 1.0 to 1.5, AER = 7.4), and digestive (n = 76, SMR = 1.9, 95% CI = 1.5 to 2.4, AER = 10.7) diseases. Cause-specific mortality varied by time since and age at LPL/WM diagnosis. Risks were highest in the first year after LPL/WM for non-malignant causes (SMR = 1.4, AER = 34.3), particularly infections (SMR = 2.4, AER = 34.4) and non-neoplastic hematologic diseases (SMR = 17.3, AER = 20.7). In contrast, risk of death due to cancers excluding lymphoma increased with time since diagnosis (SMR< 1y = 1.2, SMR≥5y = 1.7; AER< 1y = 15.1, AER≥5y = 60.0). Analyses by age, focused on AERs, showed generally similar risks across age groups (cancers excluding lymphoma: AER< 65= 26, AER65-75= 28, AER≥75= 31; non-malignant causes: AER< 65= 52, AER65-75= 66, AER≥75= 23). Cumulative mortality from non-malignant causes (23.7%) exceeded that from lymphoma (22.9%) beginning 9 years after LPL/WM diagnosis. Conclusions: Using population data, we identified areas to improve survivorship care of LPL/WM patients, particularly for non-malignant causes of death.


2021 ◽  
Vol 9 (5) ◽  
pp. 1027-1031
Author(s):  
Priyanka V. Dekate

Madhumeha (Diabetes) is attracting the world as a non-infectious pandemic/epidemic. The prevalence of Diabetes is on the rise, more alarmingly in the developing country. Ranked 7th among leading causes of death. This multiplying incidence of CVS & heart diseases. Now days Ayurveda is of wise important to get swasthya, to prevent heart diseases & stroke from DM. The objectives of study are to evolve standard Ayurvedic drug & preventive measures for Madhumeha. This study is based on review of Ayurvedic Samhitas & previous research work. DM is the 6th leading cause of death in the world. Therefore, attempt should be made to balance the Dehamanas prakruti & normal state of physiological energy to prevent Diabetes Mellitus. Dinacharya (Daily regimen), Ashtavidha aahara vidhi Aayatana & herbo mineral drugs with Yogasana help to prevent diabetes & its related complication. Keyword: Madhumeha, stroke, Heart diseases.


2015 ◽  
Vol 61 (6) ◽  
pp. 17-22 ◽  
Author(s):  
Nailya Sayfullaevna Asfandiyarova ◽  
Aleksey Aleksandrovich Nizov ◽  
Tat'yana Davydovna Zdol'nik ◽  
Irina Viktorovna Shatrova ◽  
Aleksey Anatol'evich Budylin

Aim.To study the overall mortality, mortality from cardiovascular diseases and cancer (CVD, C) in patients with diabetes mellitus (DM) in Sasovo District of Ryazan Region during 2003—2013 years.Material and Methods.We studied the diabetes overall mortality, CVD and cancer mortality dynamics in Sasovo District of Ryazan region during 2003—2013 years. In 2003, the population of the district was 52 100 people, in 2013 — 45 316. In 2003 years, it was registered 550 patients with diabetes, in 2013 years — 736.The coefficients of overall mortality, mortality from diseases were calculated according to standard formulas per 1000 population.Results.It was revealed the reduction of total and cardiovascular mortality in the population (p<0,001) during period of observation. There is a trend towards reduction in total mortality and mortality from CVD in diabetic patients (p>0,05), but it is in 2—3,4 times higher than among the population The main causes of death in diabetic patients are CVD (67.8%) and cancer (10.9%), the dynamics of these figures were not observed.Conclusions.CVD and cancer are the leading cause of death in diabetes. Absence of changes in the level of CVD mortality, suggests the need for preventive measures for influence on this risk factor.


BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e049122
Author(s):  
Sofia Klingberg ◽  
Kirsten Mehlig ◽  
Rojina Dangol ◽  
Cecilia Björkelund ◽  
Berit Lilienthal Heitmann ◽  
...  

ObjectiveTo examine height changes in middle-aged northern European women in relation to overall and cardiovascular mortality.DesignPopulation-based cohort studies with longitudinally measured heights and register-based mortality.SettingSweden and Denmark.ParticipantsPopulation-based samples of 2406 Swedish and Danish women born on selected years in 1908–1952, recruited to baseline examinations at ages 30–60, and re-examined 10–13 years later.Main outcome measureTotal and cardiovascular disease (CVD) specific mortality during 17–19 years of follow-up after last height measure.ResultsFor each 1 cm height loss during 10–13 years, the HR (95% CI) for total mortality was 1.14 (1.05 to 1.23) in Swedish women and 1.21 (1.09 to 1.35) in Danish women, independent of key covariates. Low height and high leisure time physical activity at baseline were protective of height loss, independent of age. Considering total mortality, the HR for major height loss, defined as height loss greater than 2 cm, were 1.74 (1.32 to 2.29) in Swedish women and 1.80 (1.27 to 2.54) in Danish women. Pooled analyses indicated that height loss was monotonically associated with an increased mortality, confirming a significant effect above 2 cm height loss. For cause-specific mortality, major height loss was associated with a HR of 2.31 (1.09 to 4.87) for stroke mortality, 2.14 (1.47 to 3.12) for total CVD mortality and 1.71 (1.28 to 2.29) for mortality due to causes other than CVD.ConclusionHeight loss is a marker for excess mortality in northern European women. Specifically the hazard of CVD mortality is increased in women with height loss during middle age, and the results suggest that the strongest cause-specific endpoint may be stroke mortality. The present findings suggest attention to height loss in early and mid-adulthood to identify women at high risk of CVD, and that regular physical activity may prevent early onset height loss.


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