Solitary plasmacytoma of the index finger

2014 ◽  
Vol 67 (9) ◽  
pp. 828-831
Author(s):  
Yahya Daneshbod ◽  
Pooria Ali Nowshadi ◽  
Shahrzad Negahban ◽  
Azita Aledavood ◽  
Mani Ramzi ◽  
...  

IntroductionSolitary osseous plasmacytoma rarely involves the distal extremities. We report a case and provide a brief review of the relevant literature.Case presentationWe report a 64-year-old man who presented with swelling, mild pain and a deformed right index finger. The workup led to the diagnosis of solitary osseous plasmacytoma and the patient eventually required amputation of his finger. With clinical follow-up, the disease spread to regional lymph nodes and subsequently the patient developed systemic involvement and received chemotherapy.ConclusionsSolitary osseous plasmacytoma should be considered in the differential diagnosis of distal extremity neoplasms.

FACE ◽  
2021 ◽  
pp. 273250162110536
Author(s):  
Joshua Harrison ◽  
Samantha Marley ◽  
Shawhin Shahriari ◽  
Christian Bowers ◽  
Anil Shetty

We report a rare case of an extramedullary plasmacytoma (EMP) in the frontal sinus with an indolent clinical presentation. Although a history of trauma was absent, the initial diagnosis was a mucocele, based on the radiological findings. Upon surgical excision, the patient was found to have an EMP. EMP, a form of solitary plasmacytoma, has a significantly high rate of conversion to multiple myeloma. This mandates long-term follow-up, even after successful radiotherapy and/or resection. While radiation therapy is generally considered a first line treatment for EMP, surgical intervention may provide optimal treatment in complicated cases. This case presentation highlights the prognosis of patients diagnosed with EMP.


2020 ◽  
Vol 6 (2) ◽  
pp. 83-88
Author(s):  
Vivek Agrawal ◽  
◽  
Kunal M.Ch Dholakia ◽  

ackground and Importance: Plasma Cell Dyscrasias (PCD) are a heterogeneous group of diseases having a spectrum from multiple myeloma to solitary plasmacytoma, a rare subtype, which constitutes 2 to 5% of all PCD. It typically involves axial bones but the involvement of skull bone is very rare. Case Presentation: We are reporting a case of inion bony lesion with venous sinus infiltration in a 55-year-old male patient, presented with pain, imbalance in walking, and swelling in the occipital region. Brain MRI suggested an extra-axial lesion with skull involvement and venous sinus infiltration. The tumor was infiltrating into the sinus with patent torcular venous confluence. Tumor decompression followed by radiosurgery of residual lesion was considered in pre-operative surgical planning. It was diagnosed as a case of myeloma cell disease on histopathology. Postoperative myeloma work-up confirmed the absence of any systemic involvement. The patient was given a course of radiotherapy. Conclusion: One-year follow-up with repeated MRI and myeloma investigations in the 3rd month, 6th months, and 1 year did not show any finding suggestive of progression to multiple myeloma. The follow-up of brain MRI showed a complete resolution of the residual tumor.


2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Shouwen Su ◽  
Yunxiang Lu ◽  
Yuxian Chen ◽  
Zhiyong Li

Abstract Background Cyamella,the sesamoid bones of the popliteus muscle, are rare in humans. Snapping knee is an uncommon problem which can be difficult to diagnose. Case presentation In this case, we report a 24-year-old male with snapping knee caused by symptomatic cyamella in the popliteus tendon. A large cyamella was identified upon surgery and was removed. Postoperatively, the patient had immediate relief of preoperative symptoms, and there were no signs of recurrence after 1 years of follow-up. Conclusions Although not previously suggested, symptomatic cyamella in the popliteus tendon should be considered as part of the differential diagnosis of the snapping knee.


2013 ◽  
Vol 103 (2) ◽  
pp. 141-144 ◽  
Author(s):  
Mert Keskinbora ◽  
Özkan Köse ◽  
Yildirim Karslioglu ◽  
Bahtiyar Demiralp ◽  
Mustafa Basbozkurt

Benign fibrous histiocytoma is a rare benign primary skeletal tumor that occurs frequently in the long bones and the pelvis. The calcaneus is an unusual location for benign fibrous histiocytoma. We did not identify any case of benign fibrous histiocytoma involving the calcaneus in the relevant literature. We describe a 22-year-old male patient with benign fibrous histiocytoma involving the calcaneus treated with curettage and bone grafting. At the final follow-up visit, 1 year after surgery, the patient was free of pain and walking unaided. We discuss the differential diagnosis of cystic lesions of the calcaneus. (J Am Podiatr Med Assoc 103(2): 141–144, 2013)


2017 ◽  
Vol 5 ◽  
pp. 2050313X1774099
Author(s):  
Selam Yekta Sendul ◽  
Cemile Ucgul Atilgan ◽  
Fevziye Kabukcuoglu ◽  
Semra Tiryaki Demir ◽  
Dilek Guven

Purpose: To present a young female patient with left anterior orbital leiomyoma that originates from the supraorbital neurovascular bundle. Case presentation: A 41-year-old female patient was admitted to our clinic with a complaint of swelling of the left upper eyelid. Based on the ophthalmological and imaging assessments, the excisional biopsy with the preliminary diagnosis of dermoid cyst was planned. The histopathological and immunohistochemical examinations of excised sample revealed surprisingly that the tumour was a leiomyoma. No recurrence was detected in the patient’s follow-up. Conclusion: Although it is rare, orbital leiomyoma should be considered in the differential diagnosis of patients with orbital tumour.


2021 ◽  
pp. 1-7
Author(s):  
Ajit Mishra ◽  
Mohammed Nadeem ◽  
Andiperumal Raj Prabhuraj ◽  
Paramita Paul ◽  
Dhananjaya Bhat

<b><i>Introduction:</i></b> Split cord malformations (SCMs) are developmental anomalies that are associated with a number of congenital defects. However, a combination of SCM I with a neuroenteric cyst (NEC) is extremely rare, and only 11 cases have been described in the literature. To the best of authors’ knowledge, the combination of the above two with dermoid cyst and thickened filum terminale has never been reported in the literature. <b><i>Case Presentation:</i></b> We present a case of the above combination in a 2-year-old child who underwent microsurgical excision of all 4 pathologies and complete recovery. <b><i>Conclusion:</i></b> NEC and dermoid should be considered in the differential diagnosis when imaging reveals cystic pathology along with SCM. Expeditious surgical repair resulted in an outstanding functional outcome at 1-year follow-up.


Author(s):  
Dayane Mendonça dos Santos ◽  
Claudia Rebecca Costa Cavalcante Silva ◽  
Ney Morgado Vieira Filho ◽  
Luiz Felipe Lins de Sousa Santos ◽  
Valtuir Barbosa Felix

Introdução: O plasmocitoma solitário pertence a um conjunto de desordens de células plasmáticas. É representado por uma massa lítica que pode ser encontrada nos ossos, sendo classificado como plasmocitoma solitário ósseo. O seu diagnóstico precoce é fundamental de modo a prevenir a progressão da doença para mieloma múltiplo. Relato de caso: Paciente do sexo feminino, de raça branca, com 81 anos, diagnosticada com plasmocitoma solitário ósseo em mandíbula à direita e tratada com radioterapia de 45Gy. Resultados: Dois anos após a conclusão do tratamento, a paciente continua em acompanhamento odontológico e hematológico, não demonstrando a evidência de transformação para mieloma múltiplo. Conclusão: Devido as características clínicas inespecíficas do plasmocitoma solitário ósseo, a correta utilização dos recursos atuais disponíveis para investigação da lesão possibilita um diagnóstico diferencial, assim como um acurado tratamento e uma proservação contínua da doença.Palavras Chave: Plasmócitos, Mandíbula, Mieloma múltiploABSTRACTIntroduction: Solitary plasmacytoma belongs to a set of plasma cell disorders. It is represented by a lytic mass that can be found in the bones, being classified as solitary bone plasmacytoma. Its precocious diagnosis is essential in order to prevent the progression of the disease for multiple myeloma. Case report: Female patient, Caucasian, 81 years old, diagnosed with solitary bone plasmacytoma in the right mandible and treated with 45Gy radiotherapy. Results: Two years after completion of treatment, the patient continues in dental and hematological follow-up, showing no evidence of transformation for multiple myeloma. Conclusion: Due the not specific clinical characteristics of solitary bone plasmacytoma, the correct use of available resources for investigation of injuries enables for a differential diagnosis, as well as an accurate treatment and a continuous disease preservation.Keywords: Plasma cells, Mandible, Multiple myeloma


2016 ◽  
Vol 11 (2) ◽  
pp. 200-203
Author(s):  
A. ZAMFIR-CHIRU-ANTON ◽  
◽  
A.E. STANCIU ◽  
D.C. GHEORGHE ◽  
◽  
...  

Osteomyelitis of the mandible is an uncommon disease, sometimes with severe invalidating symptoms. Some cases can present as tumors of the jaw and are possibly seen in ENT practice. Objective. To present the differential diagnosis of mandibular swellings of inflammatory origin. Material, method. Case presentation of a 9y child admitted and biopsied in the ENT department. Results. Histologic examination showed focal areas of osteolytic lesions along with moderate inflammatory cellular infiltration, all within newly formed bone. Under NSAI drugs, the symptoms were alleviated, the patient remaining under close follow-up. Conclusion. Osteomyelitis of the mandible is not always of infectious origin. The clinical examination, the imagistics and biopsy are key elements to correct diagnosis. Therapy is still under evaluation for noninfectious osteomyelitis.


2022 ◽  
pp. 014556132110725
Author(s):  
Rui Lu ◽  
Xiong Chen ◽  
Shucheng Yin ◽  
Zhiyong Li

Lipomas of the palatine tonsil are rare benign neoplasms in clinical practice. We present a case of palatine tonsillar fibroangiolipoma in a 50-year-old Chinese male with a history of multiple lipomas on the back and extremities. It was diagnosed based on histological examination and integrated analysis. Good wound healing and no evidence of recurrence were noted within 6 months follow-up after tonsillectomy. This article also puts a spotlight on the differential diagnosis of benign tonsillar tumors and reviewed recent relevant literature.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Tian-shi Ma ◽  
Ling Zhou ◽  
Quan Zhou ◽  
Xiang-lei He ◽  
Ming Zhao

Abstract Background Soft tissue perineurioma of the kidney is rare, with only a few reported cases. We report two additional cases with histologic, immunohistochemical and genetic analyses. Case presentation Both tumors were from adults (1 female aged 49 years and 1 male aged 42 years) and grossly had maximum diameters of 6.5 and 10 cm, respectively. The tumors were overall well circumscribed but unencapsulated, with focally entrapped benign native renal tubules in one case; both tumors seemed to arise in the capsular areas. The tumors had histologic and immunohistochemical profiles consistent with soft tissue perineurioma. Fluorescence in situ hybridization analyses demonstrated that the tumors were negative for amplification of MDM2 and rearrangements of ESWR1, FUS, and KMT2A. Targeted next-generation sequencing revealed a low tumor mutation burden and likely pathogenic mutations (CYP2B6 and FLT1 mutations for 1 each). Follow-up data were available for both patients; neither had tumor recurrence or metastasis. Conclusions In conclusion, renal perineurioma is rare, usually arises in the capsular areas, and is cured by resection. Low-grade dedifferentiated liposarcoma and low-grade fibromyxoid sarcoma as well as other spindle cell lesions should be considered in the differential diagnosis.


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