Delayed infection, family size and malignant lymphomas

51Cr-bleomycin was used for the scintigraphic detection of tumours and the assessment of the spread of the disease in 20 patients with various malignances: 7 with Hodgkins Lymphoma, 5 with other malignant lymphomas, 4 cases of cervix carcinoma and 4 other tumours. The scintigraphy was performed using a Toshiba GC 401 gamma camera coupled to an MDSI computer Trinary. Active foci were scored using a semiquantitative scale of 0 to 5. Results of these studies were compared with those of tests similarly carried out with 57Co-bleomycin (in 9 of the cases) and 67Ga-citrate (11 cases); they demonstrated that the properties of 51Cr-bleomycin for scintigraphic detection of neoplastic foci are similar to those of 57Co-bleomycin.

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Siblings and Illness

Vanderbilt Undergraduate Research Journal ◽

10.15695/vurj.v7i0.2924 ◽

2011 ◽

Vol 7 ◽

Author(s):

Leah Sawyer Vanderwerp

Keyword(s):

Depressive Symptoms ◽

Birth Order ◽

Family Size ◽

Multivariate Analyses ◽

Social Role ◽

Chronically Ill ◽

Demographic Variables ◽

Future Research ◽

Mother And Child ◽

Using Data

Using data from the National Longitudinal Survey of Youth-Mother and Child samples, I investigated the relationships among child and adolescent depressive symptoms, having a chronically ill sibling, and other child and familial demographic variables. From research on social support and social role transitions, with the Stress Process as a theoretical model, I hypothesized that children with chronically ill siblings experience more depressive symptoms. Specifically, I looked at age, gender, birth order and family size as potentially reducing the effect size of having a chronically ill sibling. Findings showed that having a chronically ill sibling is associated with demonstrating more depressive symptoms both in the bivariate and multivariate analyses. Although age, gender, birth order and family size do not interact significantly with having a chronically ill sibling in predicting depressive symptoms, they do present interesting findings about childhood depressive symptoms in general. Thus, the results of this study suggest specific and meaningful paths for future research.

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Identification of T and B Cell Type in Malignant Lymphomas by Acid α-Naphthyl Acetate Esterase (ANAE) Staining

Nishi Nihon Hifuka ◽

10.2336/nishinihonhifu.42.434 ◽

1980 ◽

Vol 42 (3) ◽

pp. 434-442

Author(s):

Kazuo SASAOKA ◽

Hidekazu SHINODA ◽

Sadao ANAN

Keyword(s):

B Cell ◽

Cell Type ◽

Malignant Lymphomas ◽

Acetate Esterase ◽

Naphthyl Acetate

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Evaluation of Antifungal Activity of CalvatiaCraniiformis and IverMectin as Novel Alternative Therapies for Aspergillus Niger Associated Acute Otitis Media with Special Refer to SocioDemographic Factors Among Rural Children of Diyala Province-Iraq

International Journal of Pharmaceutical and Clinical Research ◽

10.25258/ijpcr.v9i08.9583 ◽

2017 ◽

Vol 9 (08) ◽

Cited By ~ 1

Author(s):

Ghassan H. Jameel ◽

Ali Ibrahim Ali Al-Ezzy

Keyword(s):

Antifungal Activity ◽

Aspergillus Niger ◽

Otitis Media ◽

Family Size ◽

Acute Otitis Media ◽

Sociodemographic Factors ◽

P Value ◽

Rural Children ◽

Alcohol Extract ◽

Family Economy

Objectives are to determine antifungal activity of Ivermectin and Calvatiacraniiformis as a novel alternative therapy for aspergillus niger associated acute otitis media (AOM) among rural children of Diyala province; correlation of sociodemographic factors with frequency of infection. Ear swabs taken from 58 infected children and cultured onSabouraud dextrose agar for 7-14 days .Macroscopic and microscopic criteria used for diagnosis of A.niger .High isolation rate for A.niger (27.59%) among children of (4-6) years with significant difference between age groups ( p value 0.039); genders ( p value 0.004);house status(p value=0.018);family size (p value =0.00006334) and month of infection (p value=0.000). A.niger infection negatively correlated with patients age (p value =0.039), family economy and house status (p value =0.000),family size (p value =0.000). Alcohol extract of C.craniiformis (100mg, 200mg, 400mg, 500mg, 600mg, 800mg and 1000 mg) and ivermectin (0.5%,1 % and 2%) restricted the growth of A. niger after 3 days .Significance difference reported between all concentrations except 100 mg and 200 mg ; 600 mg and 800 mg. Significance difference in inhibitory activity between concentration 1% and 2%,0.5% and 2% of Ivermectin respectively. Conclusions: A.niger infections positively correlated with family size and inversely with age and family economy. The growth of A nigersignificantly restricted by alcohol extract of C.craniiformis and Ivermectin in concentration dependent manner. The powerful concentration was 1000mg, for C.craniiformis and 2% for Ivermectin. Thus, C.craniiformis and Ivermectin consider a novel antifungal agents that can be used in clinical practice for treatment of A.niger associated otitis media that represents a clinical problem in children and need serious attention from clinicians.

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PREDICTIVE SIGNIFICANCE OF HIGH SERUM FERRITIN LEVELS IN THE DEBUT OF MALIGNANT LYMPHOMA

"Medical & pharmaceutical journal "Pulse" ◽

10.26787/nydha-2686-6838-2020-22-12-74-81 ◽

2020 ◽

pp. 74-81

Author(s):

Babaeva T.N. ◽

Seregina O.B. ◽

Pospelova T.I.

Keyword(s):

Serum Ferritin ◽

Serum Ferritin Level ◽

Ferritin Level ◽

Prognostic Significance ◽

Average Concentration ◽

High Serum ◽

Control Group ◽

Malignant Neoplasms ◽

Significant Prognostic Factor ◽

Malignant Lymphomas

At present, the serum ferritin level is not included in the list of prognostic factors; however, it is known that its increased serum level in patients with malignant neoplasms relates with the tumor burden, the degree of disease activity and correlates with a worse prognosis in patients with hematologic malignancies.The normalization of serum ferritin level during remission period confirms the involving of hyperferritinemia in mechanisms of tumor progression and may testify for clinical importance of measurement of serum ferritin level in patients, including those with malignant lymphomas. Objective:The aim of this study was to assess of the prognostic significance of high ferritin levels at the onset of the disease in patients with malignant lymphomas. Materials and methods:98 patients with malignant lymphomaswere enrolled in this study, including 72 patients (73.5%) with non-Hodgkins lymphomas (NHL) and 26 patients (26.5%) with Hodgkin’s lymphoma (HL). The increased serum ferritin level (more than 350 ng/ml) was found in 53 (54.2%) patients with malignant lymphomas at the onset of disease and its average concentration was 587,62±131,6 ng/ml (8.3 times higher values of control group, p<0.001).Also the positive statistical correlationsbetween increased ferritin level and increased level of LDH (r=0.47, p<0.001, n=98) and C-reactive protein (r=0.41, p<0.001, n=98) as well as the presence of B-symptomswere found. The median OS was significantly shorter in the group of patients with increased ferritin level (more than 350 ng/ml) at the onset of disease in comparison with group of patients with normal ferritin level, where the median OS was not reach during the observation period. Patients with increased ferritin level before starting chemotherapy also showed worse results of overall survival and increased mortality risk (OR 8.122; 95% CI, 1.764-37.396;р<0.05) compare with a group of patients with ferritin level ˂350 hg/ml at the onset of disease. Conclusion:These results make it possible to include lymphomas’s patients with increased ferritin level at the onset of disease in the group with poor prognosis and lower OS, while the increased ferritin level in patients without previous blood transfusions should be considered as a significant prognostic factor.

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Family Size and Public Opinion

Soviet Review ◽

10.2753/rss1061-14281304380 ◽

1972 ◽

Vol 13 (4) ◽

pp. 380-398

Author(s):

V. A. Belova

Keyword(s):

Public Opinion ◽

Family Size

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