Femoral artery block: the relationship between visceral and ischemic pain

2021 ◽  
pp. rapm-2021-102622
Author(s):  
Andre Boezaart ◽  
Cameron Smith ◽  
Yury Zasimovich ◽  
Miguel A Reina
1987 ◽  
Author(s):  
R A Harper ◽  
I F Lane ◽  
C M Backhouse ◽  
C N McCollum ◽  
A C Meek

Platelet and fibrin accumulation in arterial grafts may cause pseudo-intimal hyperplasia and graft occlusion. The relationship between the rate of post-operative platelet accumulation and subsequent pseudo-intimal hyperplasia has been studied in prosthetic grafts implanted in greyhounds.The femoral artery in 30 greyhounds was replaced by a 6cm length of 6mm PTFE. Autologous 111In-platelet deposition over the graft was measured by probe and ratemeter for 7 days and radioactivity compared to the contralateral thigh. The daily increase in this ratio graft over reference was calculated as the Thrombogenicity Index (TI). Grafts were removed at 8 weeks and sectioned at 5, 30 and 55mm for measurement of pseudo-intimal thickening by grid microscopy.The animals subsequently developing occlusion or pseudo-intimal harrowing of greater than 50% of the lumen had a markedly greater TI of 0.22±0.027 compared to 0.03±0.019 in the 23 grafts maintaining wide patency (p<0.05). TI was highest in the 4 grafts which occluded at 0.3110.09 compared to 0.04±0.02 in the 26 that remained patent (p<0.01). There was a highly significant correlation (r=0.69) between post-operative TI and subsequent pseudo-intimal hyperplasia (p<0.001).Platelet deposition in the early post-operative period appears to promote the development of progressive pseudo-intimal thickening and ultimate occlusion


Nephron ◽  
2018 ◽  
Vol 139 (2) ◽  
pp. 159-169 ◽  
Author(s):  
Nariman Nezami ◽  
Kamyar Ghabili ◽  
Behrooz Shokouhi-Gogani ◽  
Mohammad Mirchi ◽  
Morteza Ghojazadeh ◽  
...  

1990 ◽  
Vol 259 (6) ◽  
pp. R1156-R1163 ◽  
Author(s):  
W. Maixner ◽  
R. H. Gracely ◽  
J. R. Zuniga ◽  
C. B. Humphrey ◽  
G. R. Bloodworth

The relationship between cardiovascular responses and pain produced by the submaximal-effort tourniquet procedure was evaluated in healthy humans. Graded increases in ischemic pain were associated with graded elevations in arterial blood pressure, forearm vascular resistance, and venous tone. Many of the vascular responses to muscle ischemia were typical of the cardiovascular components of the defense reaction and correlated with both the sensory and affective aspects of ischemic pain. The cardiovascular responses to arm ischemia were distinguishable from those produced by rhythmic hand exercise used to produce ischemia. Dynamic hand exercise produced a transient increase in arterial blood pressure, heart rate, and measures of hand discomfort. These responses were enhanced when dynamic hand exercise was conducted under ischemic conditions. The tightly coupled and coordinated cardiovascular responses elicited by ischemic pain represent integrated adaptive responses to painful stimulation.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Beatrice Cavallo Marincola ◽  
Alessandro Napoli ◽  
Michele Anzidei ◽  
Eugenio Marotta ◽  
Fabrizio Boni ◽  
...  

Persistent sciatic artery is a very uncommon embryologic vascular variant, with a prevalence of 0.05% based on angiographic studies. Two different types of this anomaly can occur, complete or incomplete, on the basis of the relationship between sciatic artery and femoral artery. Although many of these patients are asymptomatic, it may represent a threat to the viability of the lower extremity because of atherosclerotic degeneration resulting in aneurysmal dilatation, occlusive thrombosis, or embolic phenomena with distal complication. We present a case of a 64-year-old man with combined, complete and incomplete, type of persistent sciatic artery causing ischemic ulcer of the first toe.


2003 ◽  
Vol 35 (2) ◽  
pp. 214-219 ◽  
Author(s):  
ARNO SCHMIDT-TRUCKS??SS ◽  
ANDREAS SCHMID ◽  
BERND D??RR ◽  
MARTIN HUONKER

2019 ◽  
Vol 12 (3) ◽  
pp. 158-161
Author(s):  
Andrew Sergeevich Moshkin

Aim. Clarify common variant of the relationship of the initial parts of the femoral artery and vein among outpatients Orel. Methods. In the observation, 138 patients were examined on an outpatient basis using a Samsung Medison R7 ultrasound scanner using a 7-12 MHz linear transducer when examining the arteries and veins of the lower limbs [4]. 81 women and 57 men, aged 21 to 91 years (mean age 57.3 ± 9.9 years) were examined. Results. As a result of the observation, 6 main types of mutual relations of the initial sections of the femoral vein were distinguished on the basis of a possible cover of the anterior wall of the vein of the femoral artery among the 138 outpatients. The results are grouped by type of vascular arrangement, patients' sex, and visualization of structures. The most common option was the close non-intersecting location of the vascular trunks, and the rarest - a partial cover of the surface of the femoral vein by 1/3 and 3/4 of the femoral artery trunk. Conclusion. Knowledge of the characteristics of the relationship of large arterial and venous highways at “key points” allows us to develop the most optimal techniques for minimally invasive surgical interventions, reducing the likelihood of complications.        


2020 ◽  
Vol 40 (7) ◽  
Author(s):  
Yaobo Yang ◽  
Fangfang Ge ◽  
Jing Shen ◽  
Jianbo Song ◽  
Jiapei Xie ◽  
...  

Abstract The present study aimed to investigate the relationship between an increase in the pre- and post-operative neutrophil–lymphocyte ratio (NLR) and superficial femoral artery in-stent restenosis (ISR) rate. We recruited 199 patients that underwent superficial femoral artery stenting for lower extremity arteriosclerosis obliterans at our hospital from March 2015 to July 2018. Patients were divided into two groups according to the occurrence of ISR within 1 year (group 1, ISR and group 2, Non-ISR). The after NLR (NLRafter) and NLR change ratio (NLRratio) (P&lt;0.001) were significantly higher in group 1. A NLRafter &gt; 4.3 was associated with an odds ratio of 1.946 (95% CI [1.51–2.50]; P&lt;0.001) for the presence of ISR. A NLRratio &gt; 37.5% was associated with an odds ratio of 3.6 (95% CI [2.03–6.36]; P&lt;0.001) for occurrence of ISR. A NLRafter level &gt; 4.3 had 75% sensitivity and 76% specificity for the prediction of ISR, as identified by the ROC curve. A NLRratio level &gt; 37.5% predicted ISR with 77% sensitivity and 60% specificity. Multivariate logistic regression analysis demonstrated that NLRratio was the strongest independent predictor of ISR (P&lt;0.001). In conclusions, NLRratio could be used as a prognostic marker in superficial femoral artery stents.


2016 ◽  
Vol 23 (6) ◽  
pp. 896-902 ◽  
Author(s):  
Norihiro Kobayashi ◽  
Keisuke Hirano ◽  
Masahiro Yamawaki ◽  
Motoharu Araki ◽  
Tsuyoshi Sakai ◽  
...  

Purpose: To evaluate the clinical efficacy of poststenting fractional flow reserve (FFR) in terms of predicting restenosis in superficial femoral artery (SFA) disease. Methods: This prospective, single-center, nonrandomized study enrolled 48 patients (mean age 76±9 years; 38 men) with 51 SFA lesions from July 2013 to June 2014. Mean FFR (distal mean pressure/proximal mean pressure) and systolic FFR (distal systolic pressure/proximal systolic pressure) were calculated, and the relationship between these FFR values and restenosis at 12 months was investigated using receiver operating characteristic (ROC) curve analysis. Results: Poststenting FFR was significantly lower in the restenosis group (poststenting mean FFR 0.85±0.07 vs 0.93±0.05, p=0.001; poststenting systolic FFR 0.76±0.14 vs 0.87±0.08, p=0.015). The area under the ROC curve for restenosis in poststenting mean FFR was higher, but not statistically significant, than that in poststenting systolic FFR (0.84 vs 0.74, p=0.08). The best poststenting mean FFR cutoff value for predicting restenosis was 0.92 (sensitivity 0.64, specificity 0.91). The 4.5% restenosis rate at 12 months in the high (>0.92) poststenting mean FFR group was significantly lower (35.7%, p=0.008) than in the low (≤0.92) poststenting mean FFR group. Conclusion: Poststenting mean FFR is useful for predicting restenosis in SFA disease.


1986 ◽  
Vol 64 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Duane H. Foley

The relationship between length and the responses of helical strips of rabbit femoral and coronary arteries to vasoactive agents was investigated by conducting concentration–response determinations at the length for maximum active force (Lmax) and a shorter length. The mean effective dose (ED50) values for norepinephrine (NE) were smaller when femoral artery strips were set at Lmax, in comparison to the values at the shorter length. Maximal relaxation of femoral artery strips by adenosine was greater when the strips were set at Lmax. However, adenosine ED50 values were smaller at Lmax only in groups of strips in which responses at Lmax were obtained prior to those at the shorter length. Experiments with coronary artery strips did not demonstrate consistent relationships between strip length and ED50 values for acetylcholine (ACh) or adenosine. The results of experiments with artery strips from normotensive and those from one-kidney, one-clip hypertensive rabbits were similar. Thus, the femoral artery data indicate that helical artery strip preparations may exhibit length-dependent sensitivity to a vasodilator agent as well as vasoconstrictor agents under certain experimental conditions. However, the coronary artery data suggest that length may not affect sensitivity of isolated artery preparations from all vascular beds in the same manner.


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