Association of insulin sensitivity and muscle strength in overweight and obese sedentary postmenopausal women

2007 ◽  
Vol 32 (2) ◽  
pp. 297-301 ◽  
Author(s):  
Antony D. Karelis ◽  
Benoit Tousignant ◽  
Julie Nantel ◽  
Majorique Proteau-Labelle ◽  
Florin M. Malita ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Muscle Strength ◽  
Postmenopausal Women ◽  
Body Mass ◽  
Lower Body ◽  
Strength Index ◽  
Cross Sectional ◽  
Entire Cohort ◽  
Body Muscle ◽  
Muscle Attenuation

The objective of this study was to examine the relationship between insulin sensitivity and lower body muscle strength in overweight and obese sedentary postmenopausal women. The design of the study was cross-sectional. The study population consisted of 82 non-diabetic overweight and obese sedentary postmenopausal women (age: 58.2 ± 5.1 y; body mass index (BMI): 32.4 ± 4.6 kg·m–2). Subjects were classified by dividing the entire cohort into quartiles based on relative insulin sensitivity expressed per kilograms of lean body mass (LBM) (Q1, < 10.3, vs. Q2, 10.3–12.4, vs. Q3, 12.5–14.0, vs. Q4, >14.0 mg·min–1·kg LBM–1). We measured insulin sensitivity (using the hyperinsulinemic–euglycemic clamp technique), body composition (using dual-energy X-ray absorptiometry), visceral fat and muscle attenuation (using computed tomography), and a lower-body muscle strength index expressed as weight lifted in kilograms per kilogram of LBM (kg·kg LBM–1) (using weight-training equipment). A positive and significant relationship was observed between insulin sensitivity and the muscle strength index (r = 0.37; p < 0.001). Moreover, a moderate but significant correlation was observed between the muscle strength index and muscle attenuation (r = 0.22; p < 0.05). Finally, the muscle strength index was significantly higher in the Q4 group compared with the Q2 and Q1 groups, respectively (3.78 ± 1.13 vs. 2.99 ± 0.77 and 2.93 ± 0.91 kg·kg LBM–1; p < 0.05). Insulin sensitivity is positively associated with lower-body muscle strength in overweight and obese sedentary postmenopausal women.

Relationship between insulin sensitivity and the triglyceride–HDL-C ratio in overweight and obese postmenopausal women: a MONET study

2007 ◽  
Vol 32 (6) ◽  
pp. 1089-1096 ◽  
Author(s):  
Antony D. Karelis ◽  
Stephanie M. Pasternyk ◽  
Lyne Messier ◽  
David H. St-Pierre ◽  
Jean-Marc Lavoie ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Insulin Sensitivity ◽  
Muscle Strength ◽  
Postmenopausal Women ◽  
Body Mass ◽  
Visceral Fat ◽  
Peak Oxygen Consumption ◽  
Glucose Disposal ◽  
C Reactive Protein ◽  
Reactive Protein

The objective of this cross-sectional study was to examine the relationship between the triglyceride–HDL-cholesterol ratio (TG:HDL-C) and insulin sensitivity in overweight and obese sedentary postmenopausal women. The study population consisted of 131 non-diabetic overweight and obese sedentary postmenopausal women (age; 57.7 ± 5.0 y; body mass index (BMI), 32.2 ± 4.3 kg/m2). Subjects were characterized by dividing the entire cohort into tertiles based on the TG:HDL-C (T1 < 0.86 vs. T2= 0.86 to 1.35 vs. T3 > 1.35, respectively). We measured (i) insulin sensitivity (using the hyperinsulinenic–euglycemic clamp and homeostasis model assessment (HOMA)), (ii) body composition (using dual-energy X-ray absorptiometry), (iii) visceral fat (using computed tomography), (iv) plasma lipids, C-reactive protein, 2 h glucose concentration during an oral glucose tolerance test (2 h glucose), as well as fasting glucose and insulin, (v) peak oxygen consumption, and (vi) lower-body muscle strength (using weight training equipment). Significant correlations were observed between the TG:HDL-C and the hyperinsulinemic–euglycemic clamp (r = –0.45; p < 0.0001), as well as with HOMA (r = 0.42; p < 0.0001). Moreover, the TG:HDL-C significantly correlated with lean body mass, visceral fat, 2 h glucose, C-reactive protein, and muscle strength. Stepwise regression analysis showed that the TG:HDL-C explained 16.4% of the variation in glucose disposal in our cohort, which accounted for the greatest source of unique variance. Other independent predictors of glucose disposal were 2 h glucose (10.1%), C-reactive protein (CRP; 7.6%), and peak oxygen consumption (5.8%), collectively (including the TG:HDL-C) explaining 39.9% of the unique variance. In addition, the TG:HDL-C was the second predictor for HOMA, accounting for 11.7% of the variation. High levels of insulin sensitivity were associated with low levels of the TG:HDL-C. In addition, the TG:HDL-C was a predictor for glucose disposal rates and HOMA values in our cohort of overweight and obese postmenopausal women.

scholarly journals Effects of training volume on lower-body muscle strength in untrained young men: a contralateral control study

2018 ◽  
Vol 24 (3) ◽  
Author(s):  
Marcio A. Rinaldo ◽  
Jeferson L. Jacinto ◽  
Francis L. Pacagnelli ◽  
Leonardo Shigaki ◽  
Alex S. Ribeiro ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Young Men ◽  
Training Volume ◽  
Lower Body ◽  
Body Muscle ◽  
Control Study

scholarly journals Physical fitness and nutritional anthropometric status of children from disadvantaged communities in the Nelson Mandela Bay region

2020 ◽  
Vol 32 (1) ◽  
pp. 1-8
Author(s):  
Danielle Smith ◽  
Larissa Adams ◽  
Rosa Du Randt ◽  
Jan Degen ◽  
Stefanie Gall ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Composition ◽  
Physical Fitness ◽  
Body Mass ◽  
Muscular Strength ◽  
Background Information ◽  
Lower Body ◽  
Cross Sectional ◽  
Disadvantaged Communities ◽  
Nelson Mandela

Background: Information about the relationships between physical fitness, body composition and nutrition has increased in recent years; however, little is known about physical fitness and the coexistence of under-/overnutrition among children living in disadvantaged areas. Objectives: To determine the physical fitness status and its association with body composition, growth and selected socio- demographics in primary schoolchildren from disadvantaged communities in the Nelson Mandela Bay region. Methods: Nine hundred and sixty-five children (49% girls, M=9.5 years) participated in this cross-sectional study. Height and weight were measured to establish body mass index, and height-for-age z-scores. Physical fitness was assessed using tests from the Eurofit Physical Fitness test battery (flexibility, upper/lower body muscular strength and cardiorespiratory fitness). Between- group differences and cross-sectional associations were examined with univariate (Chi2-tests, analyses of variance) and multivariate methods (mixed linear/logistic regression). Results: Most children had normal weight (76.7%), while 4.5% were underweight and 18.7% were overweight/obese. Underweight children and children with stunted growth (11.5%) had lower average upper body strength (p<0.001). Overweight/obese children had lower scores in weight-bearing activities (p<0.001). Children with higher socio-economic status were more likely to be overweight and obese (p<0.001). In the multivariate analyses, sex, age, body mass index, and stunting were associated with children’s physical fitness. Conclusion: Fitness assessments seem to be a relevant measure of the current health status of children in disadvantaged settings. Compared to international norms, the children in this study had relatively low scores for both upper- and lower body muscular strength. Therefore, effective school-based intervention programmes should be developed to improve children’s physical fitness in disadvantaged schools.

Snacking may improve dietary fiber density and is associated with a lower body mass index in postmenopausal women

Nutrition ◽  
2021 ◽  
Vol 83 ◽  
pp. 111063
Author(s):  
Aleksandra Skoczek-Rubińska ◽  
Agata Muzsik-Kazimierska ◽  
Agata Chmurzynska ◽  
Prof. Jarosław Walkowiak ◽  
Joanna Bajerska
Keyword(s):  
Body Mass Index ◽  
Postmenopausal Women ◽  
Dietary Fiber ◽  
Body Mass ◽  
Lower Body ◽  
Fiber Density ◽  
Lower Body Mass Index

scholarly journals Prevalence of reduced respiratory muscle strength in institutionalized elderly people

2009 ◽  
Vol 127 (2) ◽  
pp. 78-83 ◽  
Author(s):  
Rodrigo Polaquini Simões ◽  
Viviane Castello ◽  
Marco Antonio Auad ◽  
Jadiane Dionísio ◽  
Marisa Mazzonetto
Keyword(s):  
Body Mass Index ◽  
Muscle Strength ◽  
Body Mass ◽  
Respiratory Muscle ◽  
Elderly Women ◽  
Respiratory Muscle Strength ◽  
Cross Sectional ◽  
Institutionalized Elderly ◽  
Anthropometric Characteristics ◽  
Predicted Values

CONTEXT AND OBJECTIVES: Respiratory muscle strength is relevant to the clinical situation of elderly patients, particularly those presenting with respiratory or cardiac diseases. The objectives of this study were to evaluate the respiratory muscle strength of institutionalized elderly women, compare this with predicted values for the Brazilian population and calculate the correlation with age and anthropometric characteristics. DESIGN AND SETTING: Cross-sectional study at the Department of Physiotherapy of Universidade Camilo Castelo Branco. METHODS: The participants were 56 institutionalized elderly women (74.87 ± 10.55 years of age), evaluated in eight institutions in three cities in the central region of the State of São Paulo, between January 2005 and March 2006. They were separated into three subgroups according to age: 60-69 years (n = 20), 70-79 (n = 18) and 80-89 years (n = 18). Maximal respiratory pressures were obtained using a manovacuometer. The values obtained were compared between subgroups and with predicted values. Correlation analysis was used to evaluate age, weight, height and body mass index in relation to maximal respiratory pressures. The significance level was P < 0.05. RESULTS: No significant differences in maximal respiratory pressures were seen between the three subgroups. The maximal respiratory pressures were significantly lower in the three subgroups, compared with predicted values. Negative correlations between maximal respiratory pressures and age and positive correlations in relation to weight, height and body mass index were found. CONCLUSIONS: Respiratory muscle strength was markedly reduced in institutionalized 60 to 89-year-old women and the values demonstrated correlations with age and anthropometric characteristics.

scholarly journals Increased 2-hydroxylation of estrogen is associated with lower body fat and increased lean body mass in postmenopausal women

Maturitas ◽  
2012 ◽  
Vol 72 (1) ◽  
pp. 66-71 ◽  
Author(s):  
Nicola Napoli ◽  
Swapna Vattikuti ◽  
Jayasree Yarramaneni ◽  
Tusar K. Giri ◽  
Srenath Nekkalapu ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Lean Body Mass ◽  
Body Mass ◽  
Body Fat ◽  
Lower Body

A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

10.1038/3099 ◽  
1998 ◽  
Vol 20 (3) ◽  
pp. 284-287 ◽  
Author(s):  
Samir S. Deeb ◽  
Lluis Fajas ◽  
Masami Nemoto ◽  
Jussi Pihlajamäki ◽  
Leena Mykkänen ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Insulin Sensitivity ◽  
Body Mass ◽  
Receptor Activity ◽  
Lower Body ◽  
Lower Body Mass Index

scholarly journals Reduced Appendicular Lean Body Mass, Muscle Strength, and Size of Type II Muscle Fibers in Patients with Spondyloarthritis versus Healthy Controls: A Cross-Sectional Study

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Kristine Røren Nordén ◽  
Hanne Dagfinrud ◽  
Amund Løvstad ◽  
Truls Raastad
Keyword(s):  
Body Composition ◽  
Muscle Strength ◽  
Lean Body Mass ◽  
Body Mass ◽  
Muscle Fibers ◽  
Type I ◽  
Healthy Controls ◽  
Type Ii ◽  
Mineral Density ◽  
Cross Sectional

Introduction. The purpose of this study was to investigate body composition, muscle function, and muscle morphology in patients with spondyloarthritis (SpA).Methods. Ten male SpA patients (mean ± SD age39±4.1years) were compared with ten healthy controls matched for sex, age, body mass index, and self-reported level of physical exercise. Body composition was measured by dual energy X-ray absorptiometry. Musculus quadriceps femoris (QF) strength was assessed by maximal isometric contractions prior to test of muscular endurance. Magnetic resonance imaging of QF was used to measure muscle size and calculate specific muscle strength. Percutaneous needle biopsy samples were taken fromm. vastus lateralis.Results. SpA patients presented with significantly lower appendicular lean body mass (LBM) (p=0.02), but there was no difference in bone mineral density, fat mass, or total LBM. Absolute QF strength was significantly lower in SpA patients (p=0.03) with a parallel trend for specific strength (p=0.08). Biopsy samples from the SpA patients revealed significantly smaller cross-sectional area (CSA) of type II muscle fibers (p=0.04), but no difference in CSA type I fibers.Conclusions. Results indicate that the presence of SpA disease is associated with reduced appendicular LBM, muscle strength, and type II fiber CSA.

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