Creating Solid Part Models Using Basic Commands I

2021 ◽  
pp. 63-100
Keyword(s):  
2021 ◽  
Vol 9 ◽  
pp. 2050313X2199920
Author(s):  
Kotaro Inoue ◽  
Kentaro Kai ◽  
Shimpei Sato ◽  
Haruto Nishida ◽  
Koji Hirakawa ◽  
...  

A 65-year-old, gravida 3, para 2 Japanese woman was referred to our hospital for symptomatic thickening of the endometrial lining. Endocervical and endometrial cytology revealed an adenocarcinoma. The endometrial biopsy specimen was mixed, with a glandular part diagnosed as endometrioid carcinoma and a solid part diagnosed as high-grade mixed large and small cell neuroendocrine carcinoma (L/SCNEC). She underwent extra-fascial hysterectomy with bilateral salpingo-oophorectomy, complete pelvic and para-aortic lymphadenectomy, and omentectomy (FIGO IIIB, pT3b pN0 M0). She currently has no deleterious germline mutation, but high tumor mutation burden and high microsatellite instability (MSI) were identified. She underwent six cycles of platinum-based frontline chemotherapy and achieved complete remission. Immune checkpoint blockade therapy is a promising second-line therapy for MSI-high solid tumors. However, the MSI or mismatch repair (MMR) status of endometrial L/SCNEC remains unclear in the literature. Universal screening for MSI/MMR status is needed, particularly for a rare and aggressive disease.


Materials ◽  
2020 ◽  
Vol 13 (12) ◽  
pp. 2678 ◽  
Author(s):  
Wei Yu ◽  
Xu Liang ◽  
Frank Mi-Way Ni ◽  
Abimbola Grace Oyeyi ◽  
Susan Tighe

This study investigated the pore structure and its effects on mechanical properties of lightweight cellular concrete (LCC) in order to understand more and detailed characteristics of such structure. As part of investigation, environment scanning electron microscopes (ESEM) and industrial high-definition (HD) macro photography camera were separately used to capture and compare images of specimens. Physical properties of the pore structure, including pore area, size, perimeter, fit ellipse, and shape descriptors, were studied based on the image processing technology and software applications. Specimens with three different densities (400, 475, and 600 kg/m3) were prepared in the laboratory. Firstly, the effects of density on the characteristics of pore structure were investigated; furthermore, mechanical properties (compressive strength, modulus of elasticity and Poisson’s ratio, flexural strength and splitting tensile strength of LCC) were tested. The relationships among pore characteristics, density, and mechanical properties were analyzed. Based on the results obtained from the lab test—comparisons made between specimens with high-densities and those with low-densities—it was found significant variability in bubble size, thickness, and irregularity of pores. Furthermore, the increase of density is accompanied by better mechanical properties, and the main influencing factors are the thickness of the solid part and the shape of the bubble. The thicker of solid part and more regular pores of LCC has, the better mechanical properties are.


Author(s):  
Vedanth Srinivasan ◽  
Kil-min Moon ◽  
David Greif ◽  
DeMing Wang ◽  
Myung-hwan Kim

In this article, we describe a newly developed modeling procedure to simulate the immersion quench cooling process using the commercial code AVL-FIRE. The boiling phase change process, triggered by the dipping hot solid part into a subcooled liquid bath and the ensuing two-phase flow is handled using an Eulerian two-fluid method. Mass transfer effects are modeled based on different boiling modes such as film or nucleate boiling regime prevalent in the system. Separate computational domains constructed for the quenched solid part and the liquid (quenchant) domain are numerically coupled at the interface of the solid-liquid boundaries using the AVL-Code-Coupling-Interface (ACCI) feature. The advanced ACCI procedure allows the information pertaining to the phase change rates in the liquid domain to appear as cooling rates on the quenched solid boundaries. As a consequence, the code handles the multiphase flow dynamics in the liquid domain in conjunction with the temperature evolution in the solid region in a tightly coupled fashion. The methodology, implemented in the commercial code AVL-FIRE, is exercised in simulating the quenching of solid parts. In part I of the present research, phase change models are validated by simulating a work piece quenching process for which measurement data are available for various water temperature ranging from 20C to 80C. The computations provide a detailed description of the vapor and temperature fields in the liquid and solid domain at various time instants. In particular, the modifications arising in the liquid-vapor flow field in the near vicinity of the solid interface as a function of the boiling mode is well accommodated. The temperature history predicted by our model at different monitoring points, under different subcooling conditions, correlate very well with the experimental data wherever available. In part II, the model is further applied to real engine cylinder head quenching process and assessment is made for the cooling curves for various measuring points. Overall, the predictive capability of the new quenching model is well demonstrated.


Author(s):  
V.N. Goldyrev ◽  
◽  
V.A. Naumov ◽  
O.B. Naumova ◽  
◽  
...  

In the coming years, the mine of LLC "Rudnik Valunisty" developing the gold and silver Valunistoe and Gornoye deposits will exhaust economically justified reserves. One of the ways to extend the life of the mine and increase the profitability of production should be the extraction of man-made secondary mineral resources. The purpose of the study is to identify the main types of solid and hydromineral form of technogenic-mineral formations at the Valunistoe Deposit, as well as to estimate the possibility of their industrial development. The useful components content was determined and calculated. The results of theoretical modeling of physical and chemical parameters of hypergenic mineral formation of the solid part of technogenic-mineral formations are shown. Objects of formation of technological waters are given. The conditions of concentration of gold and other metals are considered.


Author(s):  
Marina S. Sudakova ◽  
Eugeniya B. Terentieva ◽  
Alexey Yu. Kalashnikov

he present article focuses on GPR tomography method potential aimed at the search of functional voids and estimation of their sizes in engineering structures. The size of voids is assumed to be greater than the wavelength for usable frequency. Two examples of the GPR tomographic survey are examined: 1) a square con-crete pillar with granite coating and a square void in the center, 2) cylindrical granite column with functional spherical void which has iron walls. The following issues are considered in the article: the method, the structure of the acquired data, the picking of wanted waves, the analysis of tomographic inversion result, compared with the result of commonly used single-fold antenna geometry GPR. As a result of the research performed it was demonstrated that GPR tomography represents a good solution for the problem of detection, delineation and characterization of voids inside engineering structures. The velocity of electromagnetic waves propagated within the solid part of the column (concrete and granite) was accurately measured. The measured velocity can be con-sidered to the basis for physical properties estimation, for example humidity, voids ratio etc. The acquired quan-titative results are characterized by high quality and are more reliable compared to the results of single-fold GPR survey.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Jun Yeun Cho ◽  
Cho Sun Leem ◽  
Youlim Kim ◽  
Eun Sun Kim ◽  
Sang Hoon Lee ◽  
...  

2021 ◽  
Author(s):  
Yuanfen Yang

AbstractRenal malakoplakia is a rare form of chronic inflammatory granulomatous disease in the kidney. It occurs in adult patients with immunocompromised status or debilitating disease. In the present study, we reported a case of a 50-year-old woman with no underlying disease. This report describes the CT and pathological features of renal malakoplakia in a 50-year-old woman. Plain CT scan showed a large soft tissue mass at the middle and upper pole of the left kidney. Enhanced CT scan showed delayed enhancement in the solid part of the mass. Our results might provide some useful information for the diagnosis of renal parenchymal malakoplakia.


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