Tongue Pattern Recognition to Detect Diabetes Mellitus and Non-Proliferative Diabetic Retinopathy

2016 ◽  
pp. 663-686
Author(s):  
Bob Zhang
Keyword(s):  
Diabetes Mellitus ◽  
Pattern Recognition ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy

scholarly journals Study of aerobic bacterial conjunctival flora in patients with diabetes mellitus

2013 ◽  
Vol 5 (1) ◽  
pp. 28-32 ◽  
Author(s):  
D Karimsab ◽  
SK Razak
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Bacterial Flora ◽  
Diabetic Patients ◽  
Coagulase Negative Staphylococci ◽  
Ocular Infections ◽  
Patients With Diabetes ◽  
Conjunctival Flora ◽  
Normal Bacterial Flora

Introduction: Normal bacterial flora may be altered by a variety of factors. Objective: To study the aerobic bacterial conjunctival flora in patients with diabetes mellitus and to find its clinical significance by comparing the results to the conjunctival flora of non-diabetic subjects. Materials and methods: A total of 75 diabetic patients were included as cases and 25 nondiabetics as controls to compare the results. Specimens for the study of conjunctival flora were taken by rubbing sterile cotton-tipped swabs to the inferior palbebral conjunctiva. The conjunctival culture report of the patients with diabetic mellitus was compared to that of nondiabetic subjects. Results: Positive conjunctival cultures were seen in a higher percentage of patients with diabetes (unilateral and bilateral positive conjunctival cultures 34.66 % and 58.66 % respectively) compared to that in non-diabetic controls (unilateral and bilateral positive conjunctival cultures 24 % and 16 % respectively). Diabetics showed a higher proportion of coagulase negative staphylococci (45.33 %), compared to the non-diabetic group (16 %). Among the diabetic patients, positive conjunctival cultures were detected more frequently in those with diabetic retinopathy compared to those without retinopathy. A higher proportions of bilateral positive conjunctival cultures were seen in cases with proliferative diabetic retinopathy (38.63 %) in comparison to patients with no retinopathy and different stages of non-proliferative diabetic retinopathy. Conclusion: The conjunctival floral pattern with increased bacteria in diabetics is a predominant cause of many diabetes-related ocular infections. The presence of diabetic retinopathy is an indicator for increased colonization of conjunctiva, and its severity correlates with the severity of diabetic retinopathy. Nepal J Ophthalmol 2013; 5(9):28-32 DOI: http://dx.doi.org/10.3126/nepjoph.v5i1.7818

scholarly journals Prevalence of Diabetic Retinopathy in Type 1 and Type 2 Diabetes Mellitus Patients in North-East Poland

Medicina ◽  
2020 ◽  
Vol 56 (4) ◽  
pp. 164
Author(s):  
Wojciech Matuszewski ◽  
Angelika Baranowska-Jurkun ◽  
Magdalena M. Stefanowicz-Rutkowska ◽  
Robert Modzelewski ◽  
Janusz Pieczyński ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Lifestyle Changes ◽  
North East ◽  
Experimental Group

Background and Objectives: The global epidemic of diabetes, especially type 2 (DM2), is related to lifestyle changes, obesity, and the process of population aging. Diabetic retinopathy (DR) is the most serious complication of the eye caused by diabetes. The aim of this research was to assess the prevalence of diabetic retinopathy in type 1 and type 2 diabetes mellitus patients in north-east Poland. Materials and Methods: The eye fundus was assessed on the basis of two-field 50 degrees color fundus photographs that showed the optic nerve and macula in the center after the pupil was dilated with 1% tropicamide. Results: The experimental group included 315 (26%) patients with type 1 diabetes mellitus (DM1) and 894 (74%) patients with DM2. DM1 patients were diagnosed with DR in 32.58% of cases, with non-proliferative diabetic retinopathy (NPDR) in 24.44% of cases, proliferative diabetic retinopathy (PDR) in 1.59% of cases, diabetic macular edema (DME) in 5.40% of cases, and PDR with DME in 0.95% of cases. DR was found in DM2 patients in 23.04% of cases, NPDR in 17.11% of cases, PDR in 1.01% of cases, DME in 4.81% of cases, and PDR with DME in 0.11% of cases. Conclusions: The presented study is the first Polish study on the prevalence of diabetic retinopathy presenting a large group of patients, and its results could be extrapolated to the whole country. Diabetic retinopathy was found in 25.48% of patients in the whole experimental group. The above results place Poland within the European average, indicating the quality of diabetic care offered in Poland, based on the number of observed complications.

Effects of diabetes duration and HgA1C level on corneal endothelial morphology

2020 ◽  
pp. 112067212091481
Author(s):  
Salih Çolak ◽  
Burcu Kazanci ◽  
Dilek Ozçelik Soba ◽  
Yasemin Ozdamar Erol ◽  
Pelin Yilmazbas
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Endothelial Cell ◽  
Standard Deviation ◽  
Proliferative Diabetic Retinopathy ◽  
Coefficient Of Variation ◽  
Corneal Thickness ◽  
Healthy Individuals ◽  
Significant Difference ◽  
Corneal Endothelial Cell Density

Objective: The aim of this study is to investigate the effects of the HbA1c level and the duration of diabetes mellitus on the corneal endothelium morphology and to compare between healthy individuals and diabetes mellitus patients with non-proliferative diabetic retinopathy and proliferative diabetic retinopathy. Material and methods: Ninety patients who applied to the Health Sciences University Ulucanlar Eye Training and Research Hospital between January 2016 and January 2017 were included in this prospective randomized study. In the study, 45 diabetes mellitus patients and 45 healthy individuals were evaluated. The diabetes patients were compared in terms of HbA1c level, diabetes mellitus duration, corneal endothelial cell density, coefficient of variation, standard deviation, and hexagonality with healthy control group. Results: A statistically significant difference was found in the endothelial cell densitometer, coefficient of variation, and standard deviation measurements between the diabetes mellitus patients and the control (healthy) group. But, there was no statistically significant difference between 6A (hexagonality) and central corneal thickness measurements. There was a negative correlation between HbA1c levels and diabetes mellitus times and endothelial cell densitometer values in the patients with diabetes mellitus diagnosis and standard deviation values in the positive direction. There was a statistically significant difference between diabetes mellitus patients with the diagnosis of non-proliferative diabetic retinopathy and proliferative diabetic retinopathy in the endothelial cell densitometer and standard deviation values. But there was not any statistically significant difference between coefficient of variation, 6A, and central corneal thickness values. Conclusion: The endothelial cell densitometer in diabetes mellitus patients with retinopathy is lower than that in healthy individuals. There is a negative correlation between retinopathy severity and corneal endothelial cell density. Diabetes affects negatively not only vascular tissues but also avascular cornea.

scholarly journals DIABETIC RETINOPATHY;

2017 ◽  
Vol 24 (02) ◽  
pp. 234-238
Author(s):  
Waseem Raja Memon ◽  
Bharat Lal ◽  
Abdul Aziz Sahto
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Hba1c Level ◽  
Detailed History

Objectives: The purpose behind this study was to frequency of diabeticretinopathy at level of hba1c greater than 6.5%. Material and Methods: 130 patients with type-IIdiabetes mellitus with duration of more than >5years with HbA1c level of >6.5% were selected.After taking detailed history regarding diabetes mellitus and diabetic retinopathy, Fundoscopicexamination of eye was done. All the information was noted in proforma and analyzed usingSPSS version 16.0. Results: Frequency of diabetic retinopathy was observed in 23.85%(31/130) and in those cases average HBA1C was 8.08±0.91 (%). Regarding severity, 74.2%were non-proliferative diabetic retinopathy and 25.8(8/31) was proliferative diabetic retinopathy.Conclusion: Our study showed a higher prevalence of diabetic retinopathy more commonly inthose patients who had HbA1C more than 8%.

scholarly journals CLINICAL STUDY OF RETINOPATHY IN PATIENTS WITH DIABETES MELLITUS TYPE 1 AND TYPE 2 AND ITS ASSOCIATION WITH RISK FACTORS

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr Kalpana Singh ◽  
Dr Dhiraj Balwir ◽  
Dr Jeetendra Singh ◽  
Dr Ruchita Raikar
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Multivariate Logistic Regression Analysis ◽  
P Value ◽  
Systemic Complications ◽  
Female Ratio ◽  
Number Of Patients ◽  
Patients With Diabetes

Aim: To study the relationship between severity of diabetic retinopathy (PDR or NPDR) and systemic complications of diabetes mellitus such as Neuropathy, Nephropathy or Cardiovascular manifestation as hypertension. Methods and Materials: This prospective observational study of 100 patients suffering from diabetic retinopathy. Such patients were recruited as a part of the study and further examined for any other systemic abnormality as neuropathy, nephropathy or hypertension. Statistical Analysis: Chi square test, univariate and multivariate logistic regression analysis was performed. P value < 0.05 was taken as significant. Results: Male: Female ratio of presence of diabetic retinopathy was 2.13: 1. The rate of proliferative diabetic retinopathy (PDR) was 1.47 % in persons who had diabetes for less than 5 years to 7.35 % in persons who had diabetes more than 15 years. In our study, it was seen that nephropathy was present in 35.71 % cases with PDR as compared to 8.93% of cases with Non proliferative diabetic retinopathy (NPDR). Conclusion: Our study showed that there is a significant correlation between severity of retinopathy and duration in type 2 Diabetes mellitus patients. Maximum number of patients with Diabetes mellitus having cardiovascular involvement, had hypertension (68%).In patients suffering from neuropathy as a complication of DM, maximum number of patients had diabetic foot (56%).It was seen that the severity of diabetic retinopathy had some association with presence of nephropathy. Also it can be postulated that patients with severe NPDR and PDR have high risk of developing nephropathy than patients suffering with mild and moderate NPDR. Hence it can be recommended that all patients of diabetes mellitus suffering from clinically significant neuropathy, nephropathy or hypertension as a complication of diabetes should always be screened for presence of retinopathy. Further studies with larger sample size are to be conducted to further look into this association. Keywords: Diabetic retinopathy, Diabetic nephropathy, diabetic neuropathy, complications

scholarly journals Perbedaan Kualitas Hidup Pada Pasien Retinopati Diabetik Non-Proliferatif Berat dan Retinopati Diabetik Proliferatif di Poliklinik Vitreoretina Instalasi Rawat Jalan Pusat Mata Nasional Rumah Sakit Mata Cicendo Bandung

2019 ◽  
Vol 13 (2) ◽  
pp. 87-99
Author(s):  
Melan Nurhayati ◽  
Irma Nur Amalia ◽  
Hafsa .
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Visual Impairment ◽  
Proliferative Diabetic Retinopathy ◽  
Chi Square ◽  
Eye Health ◽  
Regular Control ◽  
Chi Square Test

Diabetic retinopathy (RD) is a specific microvascular complication of Diabetes Mellitus (DM) that causes visual impairement. Visual impairment that occurs in DR patients can affect the quality of life related to eye health. The latest data about DR patients from National Eye Center (NEC) Cicendo Eye Hospital Bandung was 2035 patients with Severe Non-proliferative Diabetic Retinopathy (Severe NPDR) and Proliferative Diabetic Retinopathy (PDR) are the most happened. The purpose of this study was to determine quality of life differences in patients with severe NPDR and PDR at the Vitreoretina Polyclinic Outpatient Departement NEC Cicendo Eye Hospital Bandung. This Research is a quantitative non-experimental with a comparative descriptive design. The sample was divided into two groups, they are Severe NPDR and PDR group, with 30 respondents each. The instrument that used in this study is the National Eye Institute Visual Function Questionaire-25 (NEI VFQ-25). Data analized by Chi Square test. The results showed that no differences in qualityof life in patients with severe NPDR and PDR in the Vitreoretina Polyclinic Outpatient Departement NEC Cicendo Eye Hospital Bandung (p = 1,000). This study illustrates the importance of providing education and encouragement to the patients with Severe NPDR and PDR for regular control about their visual impairment and their diabetes, so the patients will spared from decressing in their quality of life.

scholarly journals Resistive index of central retinal artery is a bioimaging biomarker for severity of diabetic retinopathy

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Manila Khatri ◽  
Sandeep Saxena ◽  
Manoj Kumar ◽  
Apjit Kaur Chabbra ◽  
Shashi K. Bhasker ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Roc Curve ◽  
Tertiary Care ◽  
Resistive Index ◽  
Study Groups ◽  
Central Retinal Artery ◽  
Rnfl Thickness ◽  
Retinal Artery

Abstract Background The present study was undertaken to assess the resistive index (RI) of central retinal artery (CRA) as a bioimaging biomarker for the severity of diabetic retinopathy (DR), for the first time. Methods Eighty-one consecutive patients of type 2 diabetes mellitus between the ages of 40 and 70 years were included in a tertiary care center-based cross sectional study. Severity of retinopathy was assessed according to Early Treatment Diabetic Retinopathy Study (ETDRS) classification: diabetes mellitus with no retinopathy (No DR) (n = 26); non-proliferative diabetic retinopathy (NPDR) (n = 29); and proliferative diabetic retinopathy (PDR) (n = 26). Twenty-six healthy controls of similar age were also included. Resistive index of CRA was studied using color Doppler and gray scale sonography. Central subfield thickness (CST), cube average thickness (CAT), retinal photoreceptor ellipsoid zone (EZ) disruption, and retinal nerve fiber layer (RNFL) thickness were evaluated using spectral domain optical coherence tomography. Sensitivity and specificity were assessed by receiver operating characteristic (ROC) curve. Results Mean RI of CRA for the study groups revealed significant increase with severity of diabetic retinopathy (F = 10.24, P < 0.001). The ROC curve analysis showed diagnostic accuracy of RI of CRA (area under curve = 0.841–0.999; sensitivity = 76–100%, specificity = 95.45–100%, P < 0.001) in discriminating controls and patients. Univariate regression analysis revealed significant association between the study groups and RI of CRA (P < 0.001). RI of CRA correlated positively with CST (r = 0.37), CAT (r = 0.45), EZ disruption (r = 0.43) and negatively with RNFL thickness (r = − 0.35) (P < 0.001). Conclusions Resistive index of CRA is a reliable bioimaging biomarker for the severity of DR.

Proliferative diabetic retinopathy in unsuspected diabetes mellitus: a case report

2019 ◽  
Vol 79 (2) ◽  
pp. 67-69
Author(s):  
O. Zborovska ◽  
◽  
T. Pilkevich ◽  
N. Kuryltsiv ◽  
N. Samoluk ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Case Report ◽  
Proliferative Diabetic Retinopathy
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