scholarly journals The discovery of the gluon

2014 ◽  
Vol 29 (31) ◽  
pp. 1430072 ◽  
Author(s):  
John Ellis
Keyword(s):  
Experimental Evidence ◽  
The Other ◽  
Direct Experimental Evidence ◽  
Gluon Bremsstrahlung

Soon after the postulation of quarks, it was suggested that they interact via gluons, but direct experimental evidence was lacking for over a decade. In 1976, Mary Gaillard, Graham Ross and the author suggested searching for the gluon via 3-jet events due to gluon bremsstrahlung in e+ e- collisions. Following our suggestion, the gluon was discovered at DESY in 1979 by TASSO and the other experiments at the PETRA collider.

scholarly journals THE COEXISTENCE OF PROTOZOAN-LIKE PARASITES AND MENINGOENCEPHALITIS IN MICE

1924 ◽  
Vol 40 (1) ◽  
pp. 51-62 ◽  
Author(s):  
E. V. Cowdry ◽  
F. M. Nicholson
Keyword(s):  
Experimental Evidence ◽  
Small Proportion ◽  
Clinical Symptoms ◽  
The Other ◽  
Laboratory Mice ◽  
Direct Experimental Evidence

A small proportion of laboratory mice, which appear to be normal, are in reality suffering from an obscure disease characterized by the presence of marked meningoencephalitic lesions which are often accompanied by protozoan-like parasites. Both the lesions and the parasites closely resemble others previously reported in rabbits, which likewise fail to reveal themselves by pronounced clinical symptoms. In the absence of direct experimental evidence it is suggested either that one species of parasite is capable of producing the lesions in both animals, or else that we have to do with two kinds of parasites which are closely related and, in the stages thus far observed, are indistinguishable one from the other.

Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells

2007 ◽  
Vol 293 (1) ◽  
pp. E62-E69 ◽  
Author(s):  
John E. Dominy ◽  
Jesse Hwang ◽  
Martha H. Stipanuk
Keyword(s):  
Steady State ◽  
Experimental Evidence ◽  
Cysteine Dioxygenase ◽  
Wild Type ◽  
Hepatic Expression ◽  
Direct Experimental Evidence ◽  
Homeostatic Response ◽  
Catabolic Enzyme ◽  
In Cells

Cysteine levels are carefully regulated in mammals to balance metabolic needs against the potential for cytotoxicity. It has been postulated that one of the major regulators of intracellular cysteine levels in mammals is cysteine dioxygenase (CDO). Hepatic expression of this catabolic enzyme increases dramatically in response to increased cysteine availability and may therefore be part of a homeostatic response to shunt excess toxic cysteine to more benign metabolites such as sulfate or taurine. Direct experimental evidence, however, is lacking to support the hypothesis that CDO is capable of altering steady-state intracellular cysteine levels. In this study, we expressed either the wild-type (WT) or a catalytically inactivated mutant (H86A) isoform of CDO in HepG2/C3A cells (which do not express endogenous CDO protein) and cultured them in different concentrations of extracellular cysteine. WT CDO, but not H86A CDO, was capable of reducing intracellular cysteine levels in cells incubated in physiologically relevant concentrations of cysteine. WT CDO also decreased the glutathione pool and potentiated the toxicity of CdCl2. These results demonstrate that CDO is capable of altering intracellular cysteine levels as well as glutathione levels.

How “Native” Are Heritage Speakers?

2013 ◽  
Vol 10 (2) ◽  
pp. 153-177 ◽  
Author(s):  
Silvina Montrul
Keyword(s):  
Language Learning ◽  
Experimental Evidence ◽  
Native Speakers ◽  
Learning Experience ◽  
Age Of Acquisition ◽  
The Other ◽  
Gender Agreement ◽  
Heritage Speakers ◽  
High Incidence ◽  
Incomplete Acquisition

One of the chief characteristics of heritage speakers is that they range in proficiency from “overhearers” to “native” speakers. To date, the vast majority of linguistic and psycholinguistic studies have characterized the non-target-like linguistic abilities of heritage speakers as a product of incomplete acquisition and/or attrition due to reduced exposure and opportunities to use the language during childhood. This article focuses on the other side of the problem, emphasizing instead the high incidence of native-like abilities in adult heritage speakers. I illustrate this issue with recent experimental evidence from gender agreement in Spanish, a grammatical feature that is mastered at almost 100% accuracy in production by native speakers;yet it is one of the most difficult areas to master for non-native speakers, including near-natives.I discuss how age of acquisition and language-learning experience explain these effects.

Are mesoionic compounds aromatic?

1998 ◽  
Vol 76 (6) ◽  
pp. 869-872 ◽  
Author(s):  
Alfredo Mayall Simas ◽  
Joseph Miller ◽  
Petrônio Filgueiras de Athayade Filho
Keyword(s):  
Experimental Evidence ◽  
Key Words ◽  
Dipole Moments ◽  
The Other ◽  
Side Chain ◽  
Theoretical Studies ◽  
X Ray Diffraction ◽  
Ring Plane ◽  
X Ray ◽  
Single Bonds

We have evaluated the experimental evidence relevant to the structure and character of mesoionic compounds, accumulated for more than 100 years and including X-ray diffraction studies. We have also evaluated relevant theoretical studies. All these, including our own extensive work, lead us to conclude that mesoionic compounds are not aromatic. According to our recent definition “mesoionic compounds are planar five-membered heterocyclic betaines with at least one side chain whose α-atom is also in the ring plane and with dipole moments of the order of 5 D. Electrons are delocalized over two regions separated by what are essentially single bonds. One region, which includes the a-atom of the side chain is associated with the HOMO and negative π-charge whereas the other is associated with the LUMO and positive π-charge.” Key words: mesoionic compounds, betaines, aromaticity.

Large magnetostriction and direct experimental evidence for anisotropy compensation in Tb0.4−xNdxDy0.6(Fe0.8Co0.2)1.93 Laves compounds

2014 ◽  
Vol 137 ◽  
pp. 274-276 ◽  
Author(s):  
J.J. Liu ◽  
Z.B. Pan ◽  
X.Y. Liu ◽  
Z.R. Zhang ◽  
X.H. Song ◽  
...  
Keyword(s):  
Experimental Evidence ◽  
Direct Experimental Evidence

Some notes on the relationship of plant viruses with vector and non-vector insects

Parasitology ◽  
1941 ◽  
Vol 33 (1) ◽  
pp. 110-116 ◽  
Author(s):  
Kenneth M. Smith
Keyword(s):  
Sugar Beet ◽  
Experimental Evidence ◽  
Plant Viruses ◽  
Artificial Feeding ◽  
The Body ◽  
The Other ◽  
Insect Vector ◽  
Feeding Methods ◽  
Relationship Of ◽  
The Relationship

Extracts of caterpillars and other insects are shown to inhibit the infective power of tobacco mosaic and tobacco necrosis viruses. The inhibitor is not sedimented after spinning for 2½ hr. at 30,000 r.p.m. Experiments with non-vector insects such as caterpillars have shown that the virus of sugar-beet curly-top, of tobacco ringspot and other viruses, are destroyed within the body of the insect. On the other hand, tobacco mosaic virus passes through the body of the caterpillar unchanged though greatly reduced in concentration. By the use of the specific insect vector and artificial feeding methods it was possible to recover the virus of curly-top 24 hr. after it had been injected into the blood of the caterpillar but the viruses of tobacco mosaic and tobacco necrosis could not be so recovered. Experimental evidence is given to show that the virus of beet curly-top is present in the saliva of viruliferous insects.

On invisibility and experimental evidence

2014 ◽  
Vol 18 (1) ◽  
pp. 25-26 ◽  
Author(s):  
ALBERT COSTA ◽  
MIREIA HERNÁNDEZ ◽  
MARCO CALABRIA
Keyword(s):  
Executive Function ◽  
Experimental Evidence ◽  
Executive Control ◽  
The Other ◽  
Bilingual Group

At the outset of her article Valian (2014) advocates for the existence of an effect of bilingualism on executive control (EC). She is commended for being very clear about her position. She argues that: “There is a benefit of bilingualism for executive function, but that benefit competes with other benefits that both mono- and bilinguals have to varying degrees. Depending on the composition of each group in any given experiment, the other benefits may be more plentiful in the monolingual than bilingual group (or sufficiently plentiful in both groups), so that the benefits of bilingualism are invisible. This is the possibility that I favor.”

Sign in / Sign up

Export Citation Format

Share Document