Side-to-side elbow range of movement variability in an ulnar neurodynamic test sequence variant in asymptomatic people

Background: Range of motion (ROM) asymmetry between sides is one indicator of a positive neurodynamic test, but this has been less well studied for the ulnar nerve. Objective: The purpose of this study was to investigate side-to-side variation in elbow ROM during an ulnar neurodynamic test sequence, including contralateral cervical side flexion, in 40 asymptomatic subjects. Methods: A traditional goniometer was used to measure elbow flexion ROM at two end points, onset of resistance ([Formula: see text]1) and symptom onset ([Formula: see text]1). Two repeated measures of [Formula: see text]1 and [Formula: see text]1 were taken on each side. Results: Reliability for [Formula: see text]1 and [Formula: see text]1 was found to be good (ICC [Formula: see text], SEM [Formula: see text]) with no significant difference in mean ROM between sides. A significant relationship between sides was seen ([Formula: see text] values [Formula: see text]) and [Formula: see text] values [Formula: see text]; this indicates at least 23% of the variance observed in one limb was accounted for by range in the opposite limb. This relationship was slightly stronger for [Formula: see text]1 than [Formula: see text]1. Lower bound scores indicate that intra-individual ROM difference [Formula: see text] for [Formula: see text]1 and 22° for [Formula: see text]1 would exceed normal ROM asymmetry. Conclusion: These findings provide clinicians with background information of ROM asymmetry during the ulnar neurodynamic test.

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Sagittal plane kinematics of the foot during passive ankle dorsiflexion

Prosthetics and Orthotics International ◽

10.1177/0309364611420476 ◽

2011 ◽

Vol 35 (4) ◽

pp. 425-431 ◽

Cited By ~ 13

Author(s):

Alfred Gatt ◽

Nachiappan Chockalingam ◽

Thierry Larose Chevalier

Keyword(s):

Repeated Measures ◽

Sagittal Plane ◽

Movement Analysis ◽

Range Of Movement ◽

Repeated Measures Design ◽

Significant Difference ◽

Background Measurement ◽

Foot Posture ◽

Foot Model ◽

Analysis System

Background: Measurement of ankle joint dorsiflexion is an essential examination technique that needs to be performed prior to prescription of foot orthoses since the presence or absence of ankle equinus will affect the design of such devices. The purpose of this study was to investigate the effect of foot posture on sagittal plane kinematics of various foot segments during passive dorsiflexion. Study Design: Comparative repeated measures design. Objectives: To determine the effect of foot posture on inter segmental kinematics during passive dorsiflexion. Methods: An optoelectronic movement analysis system was employed to collect kinematic data. A validated marker set (Oxford Foot Model) was applied to 16 subjects (12 males, 4 females) with a mean age of 35.5 years (range 20–56 years), who provided informed consent. An upward force was applied to the forefoot until maximum resistance. Sagittal movement of the hindfoot and forefoot segments along with the whole foot movement were analyzed in the pronated, neutral and supinated foot postures. Results: While maximum foot dorsiflexion angle showed a significant difference between the three postures ( p=0.000) the actual recorded difference between the neutral and supinated postures was only 2.49°. For the hindfoot and forefoot segments, mean angle range of movement for the pronated foot posture was significantly higher than the other foot postures. The forefoot to hindfoot angle demonstrated a significant ( p=0.005) increase during dorsiflexion between the pronated and supinated postures. These results indicate that during passive dorsiflexion, the forefoot travels through a greater degree of movement than the hindfoot. Conclusions: While the maximum foot dorsiflexion angle differs significantly between the pronated and supinated foot postures, hindfoot movement also varies significantly between foot postures. Furthermore, the forefoot to tibia angle travels through a greater range than the hindfoot to tibia angle, in all three foot postures. The hindfoot to forefoot angle does not remain constant during passive dorsiflexion, but increases upon application of a dorsiflexing force, indicating that the forefoot movement cannot be eliminated completely by placing the foot in any particular posture.

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The effect of forearm position on elbow flexion strength in nursing, occupational, and physical therapy students

Work ◽

10.3233/wor-213486 ◽

2021 ◽

pp. 1-7

Author(s):

Dennis G. O’Connell ◽

Kimberly A. Cooper ◽

Shelby M. Richeson ◽

Mathilde B. Moeller ◽

Jason W. Stephens ◽

...

Keyword(s):

Repeated Measures ◽

Pairwise Comparison ◽

Elbow Flexion ◽

Physical Therapy Students ◽

Injury Rates ◽

Repeated Measures Anova ◽

Entry Level ◽

Significant Difference ◽

Occupational And Physical Therapy ◽

Rn Students

BACKGROUND: Novice nurses, occupational and physical therapist’s injury rates are alarming. OBJECTIVE: To test for differences in peak elbow flexion forces (PEFF) by profession using different forearm positions. METHODS: Entry-level RN, OT, and PT students performed 3-repetitions of standing PEFF in forearm supination, pronation, and neutral. A one-way repeated measures ANOVA determined the forearm position with the greatest PEFF. A one-way ANOVA assessed differences in PEFF between professions. The alpha level was set at p≤0.05 for all analyses. RESULTS: Thirty 30 RN, 25 OT, and 30 PT students (x = 23.27 + /–3.29 yrs.) were studied. A one-way repeated measures ANOVA revealed a significant difference in PEFF between positions (F(2,168) = 144.3, p < 0.0001). A significant (p < 0.0001) pairwise comparison revealed neutral produced the greatest (28.15 + /–12.64 kg) and pronation the least PEFF (17.27 + /–7.40). PEFF was significantly different between position by profession (supination: F(2,82) = 10.14, p < 0.0001; pronation: F(2,82) = 10.33, p < 0.0001; neutral: F(2,82) = 13.39, p < 0.0001). PTs were significantly stronger than OTs and RN students in all forearm positions (p < 0.01). CONCLUSIONS: Neutral PEFF was greatest and PT students demonstrated greater PEFF than OT and RN students.

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Investigating the Effect of Cognitive-behavioral Stress Management on Occupational Performance among Women with Breast Cancer

Current Women s Health Reviews ◽

10.2174/1573404816666191220095123 ◽

2020 ◽

Vol 16 (2) ◽

pp. 152-159

Author(s):

Arezoo Shayan ◽

Mansoureh Refaei ◽

Farkhondeh Jamshidi

Keyword(s):

Breast Cancer ◽

Stress Management ◽

Repeated Measures ◽

Intervention Group ◽

Performance Measure ◽

Cognitive Behavioral ◽

Occupational Performance ◽

Cognitive Behavioral Stress Management ◽

Behavioral Stress ◽

Significant Difference

Background: Treatment of breast cancer can be accompanied by long-term consequences affecting women’s participation in many tasks. Objective: This study aimed to assess the effect of cognitive behavioral stress management (CBSM) program on occupational performance of women with breast cancer. Methods: In this randomized clinical trial, conducted between Feb 3 and Oct 26, 2016, 104 women with breast cancer who had referred to Imam Khomeini clinic in Hamadan, and who fulfilled the inclusion criteria (20-60 years old, married, suffering from grade 1-3 breast cancer with a history of recent surgery) were enrolled. They were randomly divided into two groups of 52 using a permuted block size of four. The intervention group took part in four 60-minute sessions of CBSM over four weeks. The study data were collected using a demographic information form and the Canadian Occupational Performance Measure. The statistical analyst was masked to intervention allocation. The data were analyzed using descriptive statistics, paired t-test, and repeated measures ANOVA. Results: A significant difference was observed between the two groups regarding the mean scores of occupational performance (p=0.02) and satisfaction (p=0.005) after the intervention. Each variable was measured at three time points (before the intervention, immediately and 2 weeks after intervention). A significant difference was observed in the two groups’ mean scores of performance (p=0.026) and satisfaction (p=0.01), irrespective of the time of assessment. Conclusion: The CBSM program promoted the occupational performance immediately and two weeks after the intervention in women with breast cancer. This technique can be used as a complementary method alongside medical therapies in oncology centers.

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Rivaroxaban for the treatment of cerebral venous thrombosis

BMC Neurology ◽

10.1186/s12883-021-02091-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Sara Esmaeili ◽

Meysam Abolmaali ◽

Sobhan Aarabi ◽

Mohammad Reza Motamed ◽

Samira Chaibakhsh ◽

...

Keyword(s):

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Vitamin K Antagonists ◽

Oral Anticoagulants ◽

Bleeding Risk ◽

Term Treatment ◽

Background Information ◽

Minor Bleeding ◽

Long Term Treatment ◽

Significant Difference

Abstract Background New Oral Anticoagulants (NOACs) such as Rivaroxaban are introduced as alternatives to conventional vitamin-K antagonists in the long-term treatment of thrombotic events due to their lower bleeding risk. There is a lack of evidence on the effectiveness and safety of Rivaroxaban in Cerebral venous thrombosis (CVT). This study aims to assess the effectiveness and bleeding risk of Rivaroxaban in comparison with Warfarin for the treatment of CVT. Materials and methods 36 patients with diagnosis of CVT were included. Clinical and background information was assessed on admission and patients were followed for at least 12 months. Measured outcomes were modified Rankin Scale (mRS), evidence of recanalization on contrast-enhanced Brain MR venography (MRV) and major or minor bleeding. Patients were divided into two groups according to the type of oral anticoagulant (Rivaroxaban vs Warfarin). Groups were compared in terms of final outcomes and side effects. Result Overall, 13 (36.11%) patients received Warfarin and 23 (63.89%) received Rivaroxaban. Optimal mRS score (0–1) was attained in 9 of 10 (90%) of patients treated with Rivaroxaban and 19 of 22 (86.36%) of patients received Warfarin. MRV showed complete or partial recanalization in 12 of 14 (85.71%) patients treated with Rivaroxaban and all patients in the Warfarin group. There was no significant difference between the two groups in terms of major and minor hemorrhage. Conclusion Rivaroxaban holds promise for the treatment of CVT.

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Cytotoxicity assessment of different doses of ozonated water on dental pulp cells

BMC Oral Health ◽

10.1186/s12903-021-01392-8 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Ferdiye Küçük ◽

Sibel Yıldırım ◽

Serap Çetiner

Keyword(s):

Cell Viability ◽

Repeated Measures ◽

Dental Pulp ◽

Control Group ◽

Dental Pulp Cells ◽

Time Points ◽

Significant Difference ◽

Pulp Cells ◽

Time Point ◽

Ozonated Water

Abstract Background The purpose of this study was to assess the cytotoxicity of various concentrations of ozonated water (OW) on human primary dental pulp cells. Methods Human primary dental pulp cells were isolated from exfoliated primary canine teeth of an 11-year-old patient with good systemic and oral health. Afterwards, cells were divided into 6 experimental groups; four groups of OW in concentrations of 2 mg/L, 4 mg/L, 8 mg/L, and 16 mg/L, untreated control group, and cell culture without cells. Cytotoxicity was evaluated after exposure for 5-min exposure using Mosmann’s Tetrazolium Toxicity (MTT) assay at 0 h and 48 h time points. Data were analyzed using a repeated measures analysis of variance and Post-hoc tests were performed using Bonferroni correction for multiple comparisons. Results All experimental groups showed proliferation at 0 h time point. However, all groups also experienced a decrease in overtime at 48 h time point (p < 0.05). At both time points 2 mg/L OW showed the highest cell viability as well as proliferation. At 0 h time point, the increase in cell viability for all experimental groups was found statistically significant when compared to positive control group (p < 0.05). At 48 h time point, although 8 mg/L and 16 mg/L OW showed statistically significant reduction in compare to 0 h time point, 2 mg/L and 4 mg/L OW groups didn’t experience any statistically significant difference (p < 0.05). Conclusion Considering our findings, due to ozonated water's induced a higher proliferation rate of dental pulp cells, indicating their biocompatibility and a possible adjuvant on irrigating agent in regenerative endodontic procedures.

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Combining Microfractures, Autologous Bone Graft, and Autologous Matrix-Induced Chondrogenesis for the Treatment of Juvenile Osteochondral Talar Lesions

Foot & Ankle International ◽

10.1177/1071100716687367 ◽

2017 ◽

Vol 38 (5) ◽

pp. 485-495 ◽

Cited By ~ 17

Author(s):

Riccardo D’Ambrosi ◽

Camilla Maccario ◽

Chiara Ursino ◽

Nicola Serra ◽

Federico Giuseppe Usuelli

Keyword(s):

Bone Graft ◽

Repeated Measures ◽

Osteochondral Lesion ◽

Young Patients ◽

Case Series ◽

Autologous Bone Graft ◽

Lesion Size ◽

Level Of Evidence ◽

Significant Difference ◽

Autologous Bone

Background: The purpose of this study was to evaluate the clinical and radiologic outcomes of patients younger than 20 years, treated with the arthroscopic-talus autologous matrix-induced chondrogenesis (AT-AMIC) technique and autologous bone graft for osteochondral lesion of the talus (OLT). Methods: Eleven patients under 20 years (range 13.3-20.0) underwent the AT-AMIC procedure and autologous bone graft for OLTs. Patients were evaluated preoperatively (T0) and at 6 (T1), 12 (T2), and 24 (T3) months postoperatively, using the American Orthopaedic Foot & Ankle Society Ankle and Hindfoot (AOFAS) score, the visual analog scale and the SF-12 respectively in its Mental and Physical Component Scores. Radiologic assessment included computed tomographic (CT) scan, magnetic resonance imaging (MRI) and intraoperative measurement of the lesion. A multivariate statistical analysis was performed. Results: Mean lesion size measured during surgery was 1.1 cm3 ± 0.5 cm3. We found a significant difference in clinical and radiologic parameters with analysis of variance for repeated measures ( P < .001). All clinical scores significantly improved ( P < .05) from T0 to T3. Lesion area significantly reduced from 119.1 ± 29.1 mm2 preoperatively to 77.9 ± 15.8 mm2 ( P < .05) at final follow-up as assessed by CT, and from 132.2 ± 31.3 mm2 to 85.3 ± 14.5 mm2 ( P < .05) as assessed by MRI. Moreover, we noted an important correlation between intraoperative size of the lesion and body mass index (BMI) ( P = .011). Conclusions: The technique can be considered safe and effective with early good results in young patients. Moreover, we demonstrated a significant correlation between BMI and lesion size and a significant impact of OLTs on quality of life. Level of Evidence: Level IV, retrospective case series.

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“Going Backward”: Effects of age and fatigue on posterior-directed falls in Parkinson disease

Neurorehabilitation ◽

10.3233/nre-210040 ◽

2021 ◽

pp. 1-9

Author(s):

Evan V. Papa ◽

Rita M. Patterson ◽

Nicoleta Bugnariu

Keyword(s):

Postural Control ◽

Parkinson Disease ◽

Repeated Measures ◽

Center Of Pressure ◽

Angular Displacement ◽

Reaction Times ◽

Older Individuals ◽

Peak Knee ◽

Significant Difference ◽

Fatiguing Exercise

BACKGROUND: Nearly half of persons with Parkinson disease (PD) report fatigue as a factor in their fall history. However, it is unknown whether these self-reported falls are caused by a sensation of fatigue or performance fatigue. OBJECTIVE: We sought to investigate the influences of performance fatigue and age on postural control in persons with PD. METHODS: Individuals with PD (n = 14) underwent postural control assessments before (T0) and immediately after (T1) fatiguing exercise. Biomechanical data were gathered on participants completing a treadmill-induced, posterior-directed fall. Performance fatigue was produced using lower extremity resistance exercise on an isokinetic ergometer. Repeated measures ANCOVAs were used with age as a covariate to determine the effects of performance fatigue on biomechanical variables. RESULTS: After adjustment for age, there was a statistically significant difference in peak center of pressure (COP) latency during the support phase of recovery. Pairwise comparisons demonstrated a decrease in peak ankle displacement from T0 to T1. Age was also found to be significantly related to reaction time and peak knee displacement while participants were fatigued. CONCLUSIONS: The decreased peak COP latency, along with decreased ankle angular displacement, suggest that persons with PD adopt a stiffening strategy in response to backward directed falls. Postural stiffening is not uncommon in persons with PD and could be a risk factor for falls. Older individuals with PD demonstrate slower mobility scores and decreased reaction times in the setting of fatigue, suggesting a combined effect of the aging and fatigue processes.

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Acute Comparative Effect of Foam Rolling and Static Stretching on Range of Motion in Rowers

Sustainability ◽

10.3390/su13073631 ◽

2021 ◽

Vol 13 (7) ◽

pp. 3631

Author(s):

Alfonso Penichet-Tomas ◽

Basilio Pueo ◽

Marta Abad-Lopez ◽

Jose M. Jimenez-Olmedo

Keyword(s):

Range Of Motion ◽

Repeated Measures ◽

Static Stretching ◽

Foam Rolling ◽

Significant Difference ◽

Post Test ◽

Alternating Treatment Design ◽

Stroke Amplitude ◽

Treatment Design ◽

Over Time

Rowers’ anthropometric characteristics and flexibility are fundamental to increase stroke amplitude and optimize power transfer. The aim of the present study was to analyze the effect of foam rolling and static stretching on the range of motion over time. Eight university rowers (24.8 ± 3.4 yrs., height 182.3 ± 6.5 cm, body mass 79.3 ± 4.6 kg) participated in an alternating treatment design study with two-way repeated measures ANOVA. The sit and reach test was used to measure the range of motion. Both in the foam rolling and in the static stretching method, a pre-test (T0), a post-test (T1), and a post-15-min test (T2) were performed. A significant effect was observed on the range of motion over time (p < 0.001), but not for time x method interaction (p = 0.680). Significant differences were found between T0 and T1 with foam rolling and static stretching (p < 0.001, d = 0.4); p < 0.001, d = 0.6). The differences between T0 and T2 were also significant with both methods (p = 0.001, d = 0.4; p < 0.001, d = 0.4). However, no significant difference was observed between T1 and T2 (p = 1.000, d = 0.1; p = 0.089, d = 0.2). Foam roller and static stretching seem to be effective methods to improve the range of motion but there seems to be no differences between them.

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Dentate nucleus signal intensity changes on T1-weighted MRI after repeated administrations of linear and macrocyclic gadolinium-based contrast agents: a pediatric intraindividual case-control study

Acta Radiologica ◽

10.1177/02841851211018809 ◽

2021 ◽

pp. 028418512110188

Author(s):

Kerem Ozturk ◽

David Nascene

Keyword(s):

Repeated Measures ◽

Signal Intensity ◽

Dentate Nucleus ◽

Pearson Correlation ◽

Gadopentetate Dimeglumine ◽

Control Groups ◽

Significant Difference ◽

Intensity Changes ◽

Cerebellar Peduncle ◽

Pediatric Brain

Background An association between consecutive administrations of macrocyclic gadolinium-based contrast agent (mcGBCA) gadobutrol and linear (L)-GBCA gadopentetate dimeglumine and gadolinium retention in the pediatric brain remains incompletely understood. Purpose To compare signal intensity (SI) changes in the dentate nucleus (DN) on unenhanced T1-weighted imaging (T1WI) in children who obtained mcGBCA gadobutrol with those who had previously received L-GBCA gadopentetate dimeglumine. Material and Methods This retrospective study included 27 children who received L-GBCA gadopentetate dimeglumine followed by mcGBCA gadobutrol and two different control groups matched for age and sex for both periods, each involving 27 individuals with no GBCA administration from January 2010 to January 2020. DN-to-middle cerebellar peduncle (MCP) SI ratios on T1WI were determined. A repeated-measures ANOVA was performed to compare the T1WI SI ratio between children exposed to GBCA in each of the two periods and controls. Pearson correlation analysis was conducted to determine any correlation between SI ratios and confounding parameters. Results T1WI SI ratio was significantly higher in those who had only L-GBCA (1.005±0.087) or subsequent mcGBCA gadobutrol (1.002±0.104) than in control groups 1 (0.927±0.041; P<0.001) and 2 (0.930±0.041; P=0.002), respectively, but no significant difference of the T1WI SI ratio was noted between L-GBCA period and subsequent mcGBCA gadobutrol period ( P=0.917). T1WI SI ratios and the L-GBCA administration number revealed a modest but significant correlation (correlation coefficient=0.034; P=0.016). Conclusion Previous administration of gadopentetate dimeglumine is associated with increased T1WI SI in the DN, while subsequent administration of gadobutrol does not demonstrate any additional SI increase in the pediatric brain.

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The Effects of Receiver Placement on Probe Microphone, Performance, and Subjective Measures with Open Canal Hearing Instruments

Journal of the American Academy of Audiology ◽

10.3766/jaaa.21.4.4 ◽

2010 ◽

Vol 21 (04) ◽

pp. 249-266 ◽

Cited By ~ 7

Author(s):

Lynzee N. Alworth ◽

Patrick N. Plyler ◽

Monika Bertges Reber ◽

Patti M. Johnstone

Keyword(s):

Repeated Measures ◽

Hearing Aid ◽

Clinical Importance ◽

Ease Of Use ◽

Subjective Measures ◽

Repeated Measures Design ◽

Hearing Instruments ◽

Data Collection And Analysis ◽

Significant Difference ◽

Occlusion Effect

Background: Open canal hearing instruments differ in method of sound delivery to the ear canal, distance between the microphone and the receiver, and physical size of the devices. Moreover, RITA (receiver in the aid) and RITE (receiver in the ear) hearing instruments may also differ in terms of retention and comfort as well as ease of use and care for certain individuals. What remains unclear, however, is if any or all of the abovementioned factors contribute to hearing aid outcome. Purpose: To determine the effect of receiver location on performance and/or preference of listeners using open canal hearing instruments. Research Design: An experimental study in which subjects were exposed to a repeated measures design. Study Sample: Twenty-five adult listeners with mild sloping to moderately severe sensorineural hearing loss (mean age 67 yr). Data Collection and Analysis: Participants completed two six-week trial periods for each device type. Probe microphone, objective, and subjective measures (quiet, noise) were conducted unaided and aided at the end of each trial period. Results: Occlusion effect results were not significantly different between the RITA and RITE instruments; however, frequency range was extended in the RITE instruments, resulting in significantly greater maximum gain for the RITE instruments than the RITA instruments at 4000 and 6000 Hz. Objective performance in quiet or in noise was unaffected by receiver location. Subjective measures revealed significantly greater satisfaction ratings for the RITE than for the RITA instruments. Similarly, preference in quiet and overall preference were significantly greater for the RITE than for the RITA instruments. Conclusions: Although no occlusion differences were noted between instruments, the RITE did demonstrate a significant difference in reserve gain before feedback at 4000 and 6000 Hz. Objectively; no positive benefit was noted between unaided and aided conditions on speech recognition tests. These results suggest that such testing may not be sensitive enough to determine aided benefit with open canal instruments. However, the subjective measures (Abbreviated Profile of Hearing Aid Benefit [APHAB] and subjective ratings) did indicate aided benefit for both instruments when compared to unaided. This further suggests the clinical importance of subjective measures as a way to measure aided benefit of open-fit devices.

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