scholarly journals Prevalence and Risk Factors of Carpal Tunnel Syndrome in Japanese Aged 50 to 89 Years

2020 ◽  
Vol 25 (03) ◽  
pp. 320-327 ◽  
Author(s):  
Shun Hashimoto ◽  
Shota Ikegami ◽  
Hikaru Nishimura ◽  
Shigeharu Uchiyama ◽  
Jun Takahashi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Japanese Population ◽  
Clinical Symptoms ◽  
Population Based ◽  
Sensory Disturbance ◽  
Tunnel Syndrome ◽  
Positive Correlations

Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy worldwide, but there are few reports investigating its prevalence using subjects diagnosed by both clinical symptoms and nerve conduction studies (NCSs) in a population-based cohort. This study aimed to determine the epidemiology of CTS diagnosed by sensory disturbance findings and NCSs using a randomly sampled resident population. Methods: Subjects aged between 50 and 89 years were randomly sampled from the basic resident registry of a rural Japanese town. Subjects indicating a history of CTS surgery in a written questionnaire were classified as having past CTS. Subjects with both sensory disturbance of the median nerve area and delays in NCSs were diagnosed as having present CTS. Subjects with past or present CTS were judged as affected with CTS. We calculated the prevalence of CTS and investigated for possible risk factors. Results: Seventeen subjects (14 female and 3 male) were affected with CTS among 379 enrolled subjects. Adjusting these results to Japanese population values, the weighted prevalence of CTS was 4.7% (female: 7.2%, male: 1.8%) in the Japanese population aged 50 to 89 years. Statistically significant positive correlations were found between CTS and female, higher BMI, rheumatoid arthritis, and trigger digit. In females affected with CTS, third metacarpal length was significantly shorter than in those without CTS. Conclusions: This epidemiological study clarified the prevalence of CTS among Japanese seniors as 4.7%. Female, higher BMI, rheumatoid arthritis, trigger digit, and shorter third metacarpal length in females were risk factors for CTS.

The Most Important Risk Factors for Carpal Tunnel Syndrome

2021 ◽  
Author(s):  
Ali Asghar Sharifi
Keyword(s):  
Risk Factors ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Clinical Symptoms ◽  
Normal Subjects ◽  
Shape Index ◽  
Mean Values ◽  
Tunnel Syndrome ◽  
Independent Risk Factors ◽  
Hand Length

Background: The aim of this study was to determine the risk factors for carpal tunnel syndrome and its relationship with the severity of the disease. Methods: A total of 131 patients with clinical symptoms of CTS and 131 normal subjects were enrolled, of whom 121 were female both in the CTS cases and the controls. All cases were electro diagnostically confirmed and assigned to three severity groups. BMI, wrist ratio, shape index, digit index and hand length/height ratio were measured in all participants. Mean values for each item were compared between cases and controls and severity subgroups. A logistic regression analysis was performed to determine independent CTS risk factors. Results: The mean values of BMI, wrist ratio and shape index were significantly higher in all CTS patients and females compared to controls, whereas in males only BMI and wrist ratio were higher. The patients in the mild severity subgroup had a significantly lower age and wrist ratio. BMI, wrist ratio and shape index were found to be independent risk factors of CTS development in all patients and females. Conclusion: Our study showed BMI, wrist ratio and shape index as independent risk factors for CTS. These findings are important anatomically and clinically and these are the risk factors of anatomical malfunction of the wrist in CTS.

scholarly journals Risk factors for operated carpal tunnel syndrome: a multicenter population-based case-control study

2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Stefano Mattioli ◽  
Alberto Baldasseroni ◽  
Massimo Bovenzi ◽  
Stefania Curti ◽  
Robin MT Cooke ◽  
...  
Keyword(s):  
Risk Factors ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Tunnel Syndrome ◽  
Control Study

Carpal Tunnel Syndrome; Its Natural History

Hand Surgery ◽  
1997 ◽  
Vol 02 (02) ◽  
pp. 129-130 ◽  
Author(s):  
Toshiro Futami ◽  
Akimasa Kobayashi ◽  
Toyohiko Ukita ◽  
Tachio Endoh ◽  
Tadashi Fujita
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Natural History ◽  
Carpal Tunnel ◽  
Clinical Symptoms ◽  
Remission Rate ◽  
Nerve Conduction Studies ◽  
Tunnel Syndrome ◽  
Male Patients ◽  
Positive Correlations ◽  
End Results

Two hundred and fifty-seven carpal tunnel syndrome patients without specific treatments were followed up for more than 5 years. Several background factors of these patients, such as possible causes, ages, sex, and involved site were surveyed in order to determine whether these factors might affect the end-results or not. The overall results showed that approximately 1/3 of untreated CTS patients were completely free from any clinical symptoms within 6 months on average. Positive correlations were found in causes, ages and sex. Younger female patients in their pregnancy had the highest remission rate; however, active middle-aged male patients had the lowest remission rate. No correlation was found between the end-results and the electrophysiological nerve conduction studies, taken at their first visits.

scholarly journals Identification of Common Risk Factors Associated with Carpal Tunnel Syndrome

2013 ◽  
Vol 29 (2) ◽  
pp. 70-78
Author(s):  
MD Nahidul Islam ◽  
Mohammad Shah Jahirul Hoque Chowdhury ◽  
MD Tauhidul Islam Chowdhury ◽  
Ahmed Hossain Chowdhury ◽  
Mahmudul Islam ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Diabetes Mellitus ◽  
Risk Factors ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Factors Associated ◽  
Group I ◽  
Tunnel Syndrome ◽  
Common Risk Factors ◽  
Group Ii

Objective: To identify the common risk factors associated with carpal tunnel syndrome. Methodology:This case-control observational study was conducted in the department of neurology and medicine, DMCH from May 2010 to April 2011 for a duration of 1 year. The study included purposively selected 80 persons. Patients attending the outdoor and admitted in indoor of department of neurology and medicine, DMCH with a clinically suspected CTS and established by electrophysiological parameters selected as cases (group –I) . Healthy volunteers and subjects who were devoid of any features of CTS but having history with isolated injury to the lower limb nerve and isolated facial nerve palsy with normal electrophysiological parameters selected as control (group –II). Data were collected by interview of the patients, clinical examination and laboratory investigations using the research instrument. Result: The mean age was 42.7±9.8 years with range from 24 to 64 years and 41.1±9.1 years with range from 26 to 61 years in group-I and group-II respectively. The proportion of male and female patients was similar in both the study groups. Male Female ratio was 1: 7 in both groups. In this study it was observed that hypothyroidism was found 25.0% in group I and 5.0% in group II, which was significantly (p<0.05) higher in carpal tunnel syndrome patients. Diabetes mellitus was significantly higher in carpal tunnel syndrome patients, which was 22.5% in group I and 7.5% in group II. Rheumatoid arthritis was found 20.0% in group I and 5.0% in group II, which was significantly (p<0.05) higher in patients with carpal tunnel syndrome. Pregnancy was found 11.4% in group I and 2.9% in group II. CKD with hemodialysis was found 17.5% and 7.5% in group I and group II respectively. In pregnancy and CKD with hemodialysis difference was not statistically significant (p>0.05) among the two groups. Regarding obesity it was found in this present series that 42.5% and 17.5% patients were obese in group I and group II respectively. Obesity was significantly (p<0.05) higher in patients with carpal tunnel syndrome. In this study it was found in multivariate analysis that patients with hypothyroidism 1.28 times, DM 2.20 times, RA disease 3.84 times, obesity 5.9 times more likely to be associated with carpal tunnel syndrome but CKD with hemodialysis patients and pregnancy were not significantly associated in multivariate analysis. In this study it was also found that almost a half (47.5%) of the patients was housewives followed by garment workers (27.5%) and clerical workers (22.5%) in group I, which indicates that carpal tunnel syndrome was more common among housewives. Conclusion: A conclusion can be made from the above mentioned result that CTS is multifactorial. Obesity, diabetes mellitus, hypothyroidism and rheumatoid arthritis are commonly associated with carpal tunnel syndrome. Moreover female sex and age were also associated with CTS. This study also found that patients diagnosed as having work-related CTS have a high prevalence of concurrent medical conditions capable of causing CTS without respect to any particular occupation. Bangladesh Journal of Neuroscience 2013; Vol. 29 (2) : 70-78

scholarly journals Association between hormone replacement therapy and carpal tunnel syndrome: a nationwide population-based study

BMJ Open ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. e055139
Author(s):  
Hsien-Chin Tang ◽  
Ya-Yun Cheng ◽  
How-Ran Guo
Keyword(s):  
Rheumatoid Arthritis ◽  
Health Insurance ◽  
Hormone Replacement Therapy ◽  
Carpal Tunnel Syndrome ◽  
Replacement Therapy ◽  
Carpal Tunnel ◽  
Hormone Replacement ◽  
Age Groups ◽  
Population Based ◽  
Tunnel Syndrome

ObjectiveCarpal tunnel syndrome (CTS) is the most common compressive focal mononeuropathy, and the increased incidence in postmenopausal and pregnant women suggests its association with oestrogen. The objective of this study is to evaluate the relationship between hormone replacement therapy (HRT) and the occurrence of CTS.DesignPopulation-based case-control study.SettingNationwide health insurance programme operated by the government with a near 100% coverage rate.ParticipantsWe identified women ≥45 years old in the Health Insurance Research Database of Taiwan, which contains data on a representative sample of one million enrollees. After exclusion of those who were diagnosed with CTS before the prescription of HRT, a total of 118 309 participants were included and followed up for 15 years starting from 1 January 1996. Both HRT and occurrence of CTS were identified using the insurance claims.Main outcome measuresWe identified incident patients of CTS and evaluated the association between HRT and CTS by calculating the OR.ResultsOf the 4535 participants who developed CTS during the study period, 2334 (51.5%) were HRT recipients. In participants without CTS, the proportion of HRT recipients was 28.1%, yielding an OR of 2.72 with a 95% CI of 2.56 to 2.88. After adjustment for age, diabetes, rheumatoid arthritis, hypothyroidism, gout and obesity, the OR of CTS associated with HRT was 2.04 (95% CI 1.91 to 2.17). While HRT, diabetes, rheumatoid arthritis and gout had similar effects on CTS across all age groups, hypothyroidism and obesity had different effects on different groups.ConclusionThis study observed a positive association between HRT and CTS, independent of age, diabetes, rheumatoid arthritis, hypothyroidism, gout and obesity. While the ORs of CTS associated with HRT were similar across age groups, those associated with hypothyroidism and obesity were not, indicating effect modifications by age.

Clinical Update: Understanding Causation: An Example Using Carpal Tunnel Syndrome

2007 ◽  
Vol 12 (6) ◽  
pp. 5-8 ◽  
Author(s):  
J. Mark Melhorn
Keyword(s):  
Risk Factors ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Legal Responsibility ◽  
Medical Evidence ◽  
Anatomic Structure ◽  
Legal Professionals ◽  
Compensation Systems ◽  
Tunnel Syndrome ◽  
Four Levels

Abstract Medical evidence is drawn from observation, is multifactorial, and relies on the laws of probability rather than a single cause, but, in law, finding causation between a wrongful act and harm is essential to the attribution of legal responsibility. These different perspectives often result in dissatisfaction for litigants, uncertainty for judges, and friction between health care and legal professionals. Carpal tunnel syndrome (CTS) provides an example: Popular notions suggest that CTS results from occupational arm or hand use, but medical factors range from congenital or acquired anatomic structure, age, sex, and body mass index, and perhaps also involving hormonal disorders, diabetes, pregnancy, and others. The law separately considers two separate components of causation: cause in fact (a cause-and-effect relationship exists) and proximate or legal cause (two events are so closely related that liability can be attached to the first event). Workers’ compensation systems are a genuine, no-fault form of insurance, and evaluators should be aware of the relevant thresholds and legal definitions for the jurisdiction in which they provide an opinion. The AMA Guides to the Evaluation of Permanent Impairment contains a large number of specific references and outlines the methodology to evaluate CTS, including both occupational and nonoccupational risk factors and assigning one of four levels of evidence that supports the conclusion.

scholarly journals POS0584 ULTRASONOGRAPHY OF THE MEDIAN NERVE IN PATIENTS WITH RHEUMATOID ARTHRITIS UNDER SUSPICION OF CARPAL TUNNEL SYNDROME

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 525.1-525
Author(s):  
S. Tsiami ◽  
E. Ntasiou ◽  
C. Krogias ◽  
R. Gold ◽  
J. Braun ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Nerve Conduction Velocity ◽  
Sectional Area ◽  
Cross Sectional ◽  
Spearman's Rho ◽  
Spearman’S Rho ◽  
Tunnel Syndrome

Background:Carpal tunnel syndrome (CTS) is the most common nerve compression syndrome and a common extra-articular manifestation of rheumatoid arthritis (RA). Different causes of CTS are known, among them inflammatory and non-inflammatory pathologies. Electroneurography (ENG) of the median nerve, the method of choice to diagnose CTS, measures impairment of nerve conduction velocity without explaining its underlying cause. However, because the electrical stimulation is often not well tolerated, ENG results may come out inconclusive. Using greyscale ultrasonography (GS-US) provides anatomic information including a structural representation of the carpal tunnel.Objectives:To investigate the performance of nerve GS-US in the diagnosis of CTS in patients with RA.Methods:Consecutive patients with active RA under suspicion of CTS presenting to a large rheumatologic center were included. Both hands were examined by an experienced neurologist including ENG and a GS-US (ML linear probe with 6-15 Hz) of the median nerve. An established grading system for ENG (1), and an established system for GS-US based on cut-offs for the nerve cross sectional area (CSA) [mild: 0,11-0,13cm2, moderate: 0,14-0,15 cm2, severe: > 0,15 cm2 CTS (2)] were used. In addition, the Boston Carpal Tunnel Syndrome Questionnaire (BCTSQ) was used to assess CTS symptoms (3).Results:Both hands of 58 patients with active RA (n=116) and clinical suspicion of CTS (in 38 cases bilaterally) were included. After clinical examination, CTS was suspicious in 96 hands (82.8%), and 59 of all hands had a final diagnosis of CTS (50.9%). Of the latter, 43 hands (72.9%) had a positive ENG and 16 (27.1%) a positive GS-US finding only, while 30 hands (50.8%) were positive in both examinations.There was a good correlation of the cross-sectional area (CSA) as well as the CSA-ratio to the ENG findings: the larger the CSA, the more severe was the CTS as assessed by ENG (Spearman’s rho=0.554; p<0.001). The more severe the GS-US findings of CTS were, the more definite were the distal motor latency (Spearman’s rho=0.554; p<0.001) and sensible nerve conduction velocity of the median nerve (Spearman’s rho=-0.5411; p<0.001).In the 46 hands positive in GS-US, tenosynovial hypertrophy of the flexor tendons was detected in 19 hands (41.3%), 7 of which (36.8%) also showed an additional cystic mass. In these 19 patients, clinical complains were more severely present than in patients with non-inflammatory CTS, as assessed by the BCTSQ with a total score of 68.8±13.4 vs. 59.3±13.7, respectively (p=0.007).Conclusion:In patients with active RA and clinical complains of CTS, ultrasound examinations provide additional information about inflammation which is helpful for a diagnosis of CTS. Thus, ENG and nerve GS-US should be used complementary for a diagnostic workup of CTS in RA patients with a suspicion of CTS. Power-Doppler may further improve the diagnostic performance of GS-US.References:[1]Padua L et al. Acta Neurol Scand 1997; 96:211–217[2]El Miedany et al., Rheumatology (Oxford). 2004 Jul; 43(7):887-895[3]Levine DW et al. J Bone Joint Surg Am 1993; 75: 1585-1592Figure 1.BCTSQ scores in patients with diagnosis of CTS and absence or presence of RA-related tenosynovial hypertrophyDisclosure of Interests:None declared

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