scholarly journals Validation of a rapid, semiautomatic image analysis tool for measurement of gastric accommodation and emptying by magnetic resonance imaging

2015 ◽  
Vol 308 (8) ◽  
pp. G652-G663 ◽  
Author(s):  
Sreerup Banerjee ◽  
Sudeepa Dixit ◽  
Mark Fox ◽  
Anupam Pal

Magnetic resonance imaging (MRI) has advantages for the assessment of gastrointestinal structures and functions; however, processing MRI data is time consuming and this has limited uptake to a few specialist centers. This study introduces a semiautomatic image processing system for rapid analysis of gastrointestinal MRI. For assessment of simpler regions of interest (ROI) such as the stomach, the system generates virtual images along arbitrary planes that intersect the ROI edges in the original images. This generates seed points that are joined automatically to form contours on each adjacent two-dimensional image and reconstructed in three dimensions (3D). An alternative thresholding approach is available for rapid assessment of complex structures like the small intestine. For assessment of dynamic gastrointestinal function, such as gastric accommodation and emptying, the initial 3D reconstruction is used as reference to process adjacent image stacks automatically. This generates four-dimensional (4D) reconstructions of dynamic volume change over time. Compared with manual processing, this semiautomatic system reduced the user input required to analyze a MRI gastric emptying study (estimated 100 vs. 10,000 mouse clicks). This analysis was not subject to variation in volume measurements seen between three human observers. In conclusion, the image processing platform presented processed large volumes of MRI data, such as that produced by gastric accommodation and emptying studies, with minimal user input. 3D and 4D reconstructions of the stomach and, potentially, other gastrointestinal organs are produced faster and more accurately than manual methods. This system will facilitate the application of MRI in gastrointestinal research and clinical practice.

2009 ◽  
Vol 16 (1) ◽  
pp. 159-168 ◽  
Author(s):  
A. Posadas ◽  
R. Quiroz ◽  
A. Tannús ◽  
S. Crestana ◽  
C. M. Vaz

Abstract. The study of water movement in soils is of fundamental importance in hydrologic science. It is generally accepted that in most soils, water and solutes flow through unsaturated zones via preferential paths or fingers. This paper combines magnetic resonance imaging (MRI) with both fractal and multifractal theory to characterize preferential flow in three dimensions. A cubic double-layer column filled with fine and coarse textured sand was placed into a 500 gauss MRI system. Water infiltration through the column (0.15×0.15×0.15 m3) was recorded in steady state conditions. Twelve sections with a voxel volume of 0.1×0.1×10 mm3 each were obtained and characterized using fractal and multifractal theory. The MRI system provided a detailed description of the preferential flow under steady state conditions and was also useful in understanding the dynamics of the formation of the fingers. The f(α) multifractal spectrum was very sensitive to the variation encountered at each horizontally-oriented slice of the column and provided a suitable characterization of the dynamics of the process identifying four spatial domains. In conclusion, MRI and fractal and multifractal analysis were able to characterize and describe the preferential flow process in soils. Used together, the two methods provide a good alternative to study flow transport phenomena in soils and in porous media.


Physiology ◽  
1988 ◽  
Vol 3 (4) ◽  
pp. 148-154
Author(s):  
MW Vannier ◽  
CM Speidel ◽  
DL Rickman

The application of NASA multispectral image processing technology for analysis of magnetic resonance imaging scans has been studied. Software and hardware capability has been developed, and a statistical evaluation of multispectral analysis application to magnetic resonance imaging scans of the head has been performed.


2003 ◽  
Vol 3 (3) ◽  
pp. 123-129 ◽  
Author(s):  
G. P. Liney ◽  
A. Heathcote ◽  
A. Jenner ◽  
L. W. Turnbull ◽  
A. W. Beavis

This work describes the feasibility of using a polymer-based tissue equivalent gel for measuring radiation doses in situ. The gel is based on the MAGIC formulation thereby enabling it to be manufactured under normal atmospheric conditions. Its composition has been altered to achieve a similar sensitivity to the more widely used, but technically more difficult to produce, PAG gels. Irradiation of the gel material causes polymerisation of the molecular structure resulting in a shortening of transverse relaxation time (T2), which can be imaged using Magnetic Resonance Imaging (MRI). This work calibrates the radiation response in terms of transverse relaxation rate (R2) and uses this information to provide absolute dose verification in a separate gel, which has been previously irradiated to a known configuration. Results demonstrate that this technique is able to verify radiation doses to within a few percent of delivered intent in three dimensions and with high spatial resolution. This work may be followed by anyone with an interest in the quality assurance of advanced conformal radiotherapy delivery methods.


PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0159803 ◽  
Author(s):  
Matthias C. Roethke ◽  
Timur H. Kuru ◽  
Maya B. Mueller-Wolf ◽  
Erik Agterhuis ◽  
Christopher Edler ◽  
...  

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