Pulsatile and Steady Pressure-Flow Relations in the Vascular Bed of the Hind Leg of the Dog

1956 ◽  
Vol 185 (2) ◽  
pp. 351-354 ◽  
Author(s):  
James E. Randall ◽  
Ralph W. Stacy

Instantaneous pressure and flow in the femoral artery of the dog were recorded under steady and pulsatile pressure conditions. Static pressure-flow diagrams and dynamic pressure-flow diagrams over the pulse pressure range at different points in the cardiac cycle were constructed. A comparison was made of the flow corresponding to a) normal pulsatile conditions, and b) static pressures equal to the mean of the pulsatile pressures. The static pressure-flow diagrams were consistent with those described by other workers, and were essentially linear in the ranges studied. Changing from steady to pulsating pressures altered the flow from 40.4 ml/min. to 40.9 ml/min. This difference was less than the measurement accuracy of the flow, although statistical analysis indicated significance to 1%. The dynamic pressure-flow diagram appeared as a ‘loop,’ the shape of which indicated that in 12 of 13 animals, the system was mass controlled and the heart rate was higher than the resonant frequency. In the one exception, the phase angle was negligible and the system was apparently in resonance.

1965 ◽  
Vol 69 (650) ◽  
pp. 136-137 ◽  
Author(s):  
N. Rajaratnam

Of the Several Methods available for the measurement of boundary shear, the simplest is perhaps the Preston tube. It is a total head tube resting on the boundary for which the difference between the dynamic pressure on the tube and the static pressure on the boundary is correlated with the boundary shear. It was evolved by Preston in 1954 mainly from similarity considerations and the existence of the wall law. In 1955, Hsu obtained Preston's original calibration curve theoretically for the one-seventh power law. In this note, a theoretical calibration curve is developed for the logarithmic law which describes the velocity distribution for larger Reynolds Numbers.


1944 ◽  
Vol 48 (397) ◽  
pp. 12-23
Author(s):  
R. Schmidt

The speed of flight of an aircraft at high altitudes is still usually determined by the indirect method of measuring the dynamic pressure in flight. The acknowledged defects of this method—the effect of interference by near parts of the aircraft on the static pressure at the tapping point, the necessity of calibration of the pressure readings by tedious quadrilateral flights over measured ground distances or a suspended static head, the indeterminate effect of the Mach number at high speeds, inaccuracy of the ‘air temperature measurements owing to stagnation of the flow at the instrument, errors of the elastic pressure capsule owing to hysteresis and temperature variations, and the inaccuracy of the mean values obtained by averaging the measured dynamic pressures—have all contributed to raise a demand for a simpler and more accurate method of airspeed measurement.


2006 ◽  
Vol 129 (3) ◽  
pp. 368-375 ◽  
Author(s):  
Shigenori Takada ◽  
Norio Tagawa ◽  
Atsunobu Mori ◽  
Yoshiaki Mizoh ◽  
Masaru Nakakita

It is important to clarify the characteristics of flow-induced vibrations in hard disk drives in order to achieve an ultrahigh magnetic recording density. In particular, it is necessary to reduce the flow-induced disk vibrations referred to as disk flutter. This paper describes the correlation between the disk vibration amplitude and the pressure fluctuation between a pair of high-speed corotating disks. It also reveals the effects of the arm thickness and arm shape on the disk vibrations and the static pressure between the disks. The disk vibrations were measured using a laser Doppler vibrometer (LDV). The static pressure downstream of the arm between a pair of narrow disks was measured by a method in which a side-hole needle was used as a measurement probe. In addition, the direction of air flow along the trailing edge of the arm was measured using a hot-wire anemometer. The experimental results revealed that the arm inserted between the disks suppresses the disk vibrations. However, the shape and thickness of the arm did not quantitatively affect the disk vibrations. The root-mean-square (RMS) static pressure fluctuation downstream of the arm decreased remarkably, whereas the mean static pressure increased when the arm was inserted between the disks. Furthermore, the circumferential variations in both the RMS and mean static pressures reduced when the arm was inserted. Therefore, it is suggested that the disk vibrations are excited by an increase in the static pressure fluctuation, mean dynamic pressure, and circumferential variation in the static pressure between the disks. Consequently, the disk vibrations can be suppressed by inserting the arm or a spoiler.


2018 ◽  
Vol 1 (March 2018) ◽  
Author(s):  
S.A Okanlawon ◽  
O.O Odunjo ◽  
S.A Olaniyan

This study examined Residents’ evaluation of turning transport infrastructure (road) to spaces for holding social ceremonies in the indigenous residential zone of Ogbomoso, Oyo State, Nigeria. Upon stratifying the city into the three identifiable zones, the core, otherwise known as the indigenous residential zone was isolated for study. Of the twenty (20) political wards in the two local government areas of the town, fifteen (15) wards that were located in the indigenous zone constituted the study area. Respondents were selected along one out of every three (33.3%) of the Trunk — C (local) roads being the one mostly used for the purpose in the study area. The respondents were the residents, commercial motorists, commercial motorcyclists, and celebrants. Six hundred and forty-two (642) copies of questionnaire were administered and harvested on the spot. The Mean Analysis generated from the respondents’ rating of twelve perceived hazards listed in the questionnaire were then used to determine respondents’ most highly rated perceived consequences of the practice. These were noisy environment, Blockage of drainage by waste, and Endangering the life of the sick on the way to hospital; the most highly rated reasons why the practice came into being; and level of acceptability of the practice which was found to be very unacceptable in the study area. Policy makers should therefore focus their attention on strict enforcement of the law prohibiting the practice in order to ensure more cordial relationship among the citizenry, seeing citizens’ unacceptability of the practice in the study area.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1076.1-1077
Author(s):  
L. Moroni ◽  
L. Giudice ◽  
G. A. Ramirez ◽  
S. Sartorelli ◽  
A. Cariddi ◽  
...  

Background:Subglottic stenosis (SGS) is defined as airway narrowing below the vocal cords and is a common and potentially life-threatening manifestation of Granulomatosis with Polyangiitis (GPA), with an estimated prevalence of 16-23% (1). Balloon catheter dilation is effective in GPA-related SGS, but relapses are frequent. Little is known about the role of immunosuppression in this setting.Objectives:to analyse the clinical characteristics of a monocentric GPA cohort, describe phenotype differences among patients with and without SGS and investigate the role of surgical and medical treatments on relapse risk and general outcome.Methods:Biopsy-proven patients with SGS were identified by review of medical charts among a cohort of patients with GPA, classified according to the algorithm of the European Medicine Agency (2). The clinical characteristics of patients with SGS were retrospectively collected over a median follow-up time of 15.9 years and compared to those of patients without SGS.Results:Fourteen patients with SGS-GPA were identified, with a female to male ratio of 1:1 and a prevalence of 29.2% among the cohort. The mean ± SD age at GPA onset was 30.8 ± 14.4 years, with a mean time from GPA diagnosis to SGS onset of 4.7 ± 4.2 years. ANCA were positive in 78.6% (54.0% anti-PR3, 18.1% anti-MPO and 27.9% IFI only). The mean Birmingham Vasculitis Activity Score (BVAS) at onset was 10.0 ± 5.6. The main clinical manifestations associated with SGS were crusty rhinitis (100%), sinusitis (78%), pulmonary disease (72.7%), otitis/mastoiditis (50%), glomerulonephritis (42.9%), orbital pseudotumor (28.6%). Six patients (42.9%) received medical treatment only, other six (42.9%) had one to three balloon dilations and two (14.2%) underwent four or more procedures. Eight patients had no SGS relapse (maximum one dilation) and they all received immunosuppression with rituximab (RTX), cyclophosphamide (CYC) or azathioprine (AZA). All patients who received no immunosuppression, methotrexate (MTX) or mycophenolate (MMF) had at least one relapse. Patients treated with MTX or MMF had a mean relapse-free survival of 13.1 months, which was comparable to the one of patients not receiving medical treatment (40.2 months; p=NS) and shorter than the one of patients receiving CYC or RTX (153.2 months; p=0.032). CYC use also inversely correlated with the number of surgical procedures (r=-0.691, p=0.006). Compared to patients without SGS (31 consecutive patients with at least 4 years of follow-up), patients with SGS-GPA had an earlier disease onset (mean age 30.8 vs 50.4 years; p<0.001), but with lower BVAS (mean 10.0 vs 15.3; p=0.013) and showed a higher prevalence of crusty rhinitis (100% vs 67.7%; p=0.019). No difference was observed in damage accrual over time between the two groups.Conclusion:Subglottic stenosis is highly prevalent in patients with GPA and may define a milder disease subset occurring more frequently in younger patients. MTX and MMF might be insufficient to prevent SGS relapses requiring balloon dilation. Aggressive immunosuppression (CYC or RTX) might have a non-redundant role in this setting and reduce the risk of relapses.References:[1]Quinn KA, et al. Subglottic stenosis and endobronchial disease in granulomatosis with polyangiitis. Rheumatology 2019; 58 (12), 2203-2211.[2]Watts R, et al. Development and validation of a consensus methodology for the classification of the ANCA associated vasculitides and polyarteritis nodosa for epidemiological studies. Ann Rheum Dis 2007; 66: 222-7.Disclosure of Interests:Luca Moroni: None declared, Laura Giudice: None declared, Giuseppe Alvise Ramirez: None declared, Silvia Sartorelli: None declared, adriana cariddi: None declared, Angelo Carretta: None declared, Enrica Bozzolo: None declared, Lorenzo Dagna Grant/research support from: The Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR) received unresctricted research/educational grants from Abbvie, Bristol-Myers Squibb, Celgene, Janssen, Merk Sharp & Dohme, Mundipharma Pharmaceuticals, Novartis, Pfizer, Roche, Sanofi-Genzyme, and SOBI., Consultant of: Prof Lorenzo Dagna received consultation honoraria from Abbvie, Amgen, Biogen, Bristol-Myers Squibb, Celltrion, Novartis, Pfizer, Roche, Sanofi-Genzyme, and SOBI.


Author(s):  
Phan Thành Nam ◽  
Marcin Napiórkowski

AbstractWe consider the homogeneous Bose gas on a unit torus in the mean-field regime when the interaction strength is proportional to the inverse of the particle number. In the limit when the number of particles becomes large, we derive a two-term expansion of the one-body density matrix of the ground state. The proof is based on a cubic correction to Bogoliubov’s approximation of the ground state energy and the ground state.


2021 ◽  
Vol 163 (4) ◽  
pp. 1191-1198
Author(s):  
Andreas K. Demetriades ◽  
Marco Mancuso-Marcello ◽  
Asfand Baig Mirza ◽  
Joseph Frantzias ◽  
David A. Bell ◽  
...  

Abstract Introduction Isolated acute bilateral foot drop due to degenerative spine disease is an extremely rare neurosurgical presentation, whilst the literature is rich with accounts of chronic bilateral foot drop occurring as a sequela of systemic illnesses. We present, to our knowledge, the largest case series of acute bilateral foot drop, with trauma and relevant systemic illness excluded. Methods Data from three different centres had been collected at the time of historic treatment, and records were subsequently reviewed retrospectively, documenting the clinical presentation, radiological level of compression, timing of surgery, and degree of neurological recovery. Results Seven patients are presented. The mean age at presentation was 52.1 years (range 41–66). All patients but one were male. All had a painful radiculopathic presentation. Relevant discopathy was observed from L2/3 to L5/S1, the commonest level being L3/4. Five were treated within 24 h of presentation, and two within 48 h. Three had concomitant cauda equina syndrome; of these, the first two made a full motor recovery, one by 6 weeks follow-up and the second on the same-day post-op evaluation. Overall, five out of seven cases had full resolution of their ankle dorsiflexion pareses. One patient with 1/5 power has not improved. Another with 1/5 weakness improved to normal on the one side and to 3/5 on the other. Conclusion When bilateral foot drop occurs acutely, we encourage the consideration of degenerative spinal disease. Relevant discopathy was observed from L2/3 to L5/S1; aberrant innervation may be at play. Cauda equina syndrome is not necessarily associated with acute bilateral foot drop. The prognosis seems to be pretty good with respect to recovery of the foot drop, especially if partial at presentation and if treated within 48 h.


Energies ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1766 ◽  
Author(s):  
Alessandro Suardi ◽  
Sergio Saia ◽  
Walter Stefanoni ◽  
Carina Gunnarsson ◽  
Martin Sundberg ◽  
...  

The collection of residues from staple crop may contribute to meet EU regulations in renewable energy production without harming soil quality. At a global scale, chaff may have great potential to be used as a bioenergy source. However, chaff is not usually collected, and its loss can consist of up to one-fifth of the residual biomass harvestable. In the present work, a spreader able to manage the chaff (either spreading [SPR] on the soil aside to the straw swath or admixed [ADM] with the straw) at varying threshing conditions (with either 1 or 2 threshing rotors [1R and 2R, respectively] in the combine, which affects the mean length of the straw pieces). The fractions of the biomass available in field (grain, chaff, straw, and stubble) were measured, along with the performances of both grain harvesting and baling operations. Admixing chaff allowed for a slightly higher amount of straw fresh weight baled compared to SPR (+336 kg straw ha−1), but such result was not evident on a dry weight basis. At the one time, admixing chaff reduced the material capacity of the combine by 12.9%. Using 2R compared to 1R strongly reduced the length of the straw pieces, and increased the bale unit weight; however, it reduced the field efficiency of the grain harvesting operations by 11.9%. On average, the straw loss did not vary by the treatments applied and was 44% of the total residues available (computed excluding the stubble). In conclusion, admixing of chaff with straw is an option to increase the residues collected without compromising grain harvesting and straw baling efficiencies; in addition, it can reduce the energy needs for the bale logistics. According to the present data, improving the chaff collection can allow halving the loss of residues. However, further studies are needed to optimise both the chaff and the straw recoveries.


1998 ◽  
Vol 11 (1) ◽  
pp. 565-565
Author(s):  
G. Cayrel de Strobel ◽  
R. Cayrel ◽  
Y. Lebreton

After having studied in great detail the observational HR diagram (log Teff, Mbol) composed by 40 main sequence stars of the Hyades (Perryman et al.,1997, A&A., in press), we have tried to apply the same method to the observational main sequences of the three next nearest open clusters: Coma Berenices, the Pleiades, and Praesepe. This method consists in comparing the observational main sequence of the clusters with a grid of theoretical ZAMSs. The stars composing the observational main sequences had to have reliable absolute bolometric magnitudes, coming all from individual Hipparcos parallaxes, precise bolometric corrections, effective temperatures and metal abundances from high resolution detailed spectroscopic analyses. If we assume, following the work by Fernandez et al. (1996, A&A,311,127), that the mixing-lenth parameter is solar, the position of a theoretical ZAMS, in the (log Teff, Mbol) plane, computed with given input physics, only depends on two free parameters: the He content Y by mass, and the metallicity Z by mass. If effective temperature and metallicity of the constituting stars of the 4 clusters are previously known by means of detailed analyses, one can deduce their helium abundances by means of an appropriate grid of theoretical ZAMS’s. The comparison between the empirical (log Teff, Mbol) main sequence of the Hyades and the computed ZAMS corresponding to the observed metallicity Z of the Hyades (Z= 0.0240 ± 0.0085) gives a He abundance for the Hyades, Y= 0.26 ± 0.02. Our interpretation, concerning the observational position of the main sequence of the three nearest clusters after the Hyades, is still under way and appears to be greatly more difficult than for the Hyades. For the moment we can say that: ‒ The 15 dwarfs analysed in detailed in Coma have a solar metallicity: [Fe/H] = -0.05 ± 0.06. However, their observational main sequence fit better with the Hyades ZAMS. ‒ The mean metallicity of 13 Pleiades dwarfs analysed in detail is solar. A metal deficient and He normal ZAMS would fit better. But, a warning for absorption in the Pleiades has to be recalled. ‒ The upper main sequence of Praesepe, (the more distant cluster: 180 pc) composed by 11 stars, analysed in detail, is the one which has the best fit with the Hyades ZAMS. The deduced ‘turnoff age’ of the cluster is slightly higher than that of the Hyades: 0.8 Gyr instead of 0.63 Gyr.


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