Functional restitution of cardiac control in heart transplant patients

2002 ◽  
Vol 282 (3) ◽  
pp. R900-R908 ◽  
Author(s):  
Eran Toledo ◽  
Itzhak Pinhas ◽  
Dan Aravot ◽  
Yael Almog ◽  
Solange Akselrod
Keyword(s):  
High Frequency ◽  
Sinoatrial Node ◽  
Control Group ◽  
Control Mechanisms ◽  
Very High Frequency ◽  
Transplant Patients ◽  
Cardiac Control ◽  
Principal Finding ◽  
Noninvasive Characterization ◽  
The Time Domain

Cardiovascular control is fundamentally altered after heart transplantation (HT) because of surgical denervation of the heart. The main goal of this work was the noninvasive characterization of cardiac rate control mechanisms after HT and the understanding of their nature. We obtained 25 recordings from 13 male HT patients [age = 28–68 yr, time after transplant (TAT) = 0.5–62.5 mo]. The control group included 14 healthy men (age = 28–59 yr). Electrocardiogram, continuous blood pressure (BP), and respiration were recorded for 45 min in the supine position and then during active change of posture (CP) to standing. The signals were analyzed in the time domain [mean and variance of heart rate (HR) and rise time of HR in response to CP] and the frequency domain [low and high frequency (LF and HF)]. Our principal finding was the consistent pattern of evolution of the HR response to standing: from no response, via a slow response (>40 s, TAT > 6 wk), to a fast increase (<20 s, TAT > 24 mo). HR response correlated with TAT ( P < 0.001). LF correlated with HR response to CP ( P < 0.0001); HF and HR did not. An important finding was the presence of very-high-frequency peaks in the power spectrum of HR and BP fluctuations. Extensive arrhythmias tended to appear at the TAT that corresponds to the transition from slow to fast HR response to CP. Our results indicate a biphasic evolution in cardiac control mechanisms from lack of control to a first-order control loop followed by partial sympathetic reinnervation and, finally, the direct effect of the old sinoatrial node on the pacemaker cell of the new sinoatrial node. There was no indication of vagal reinnervation.

scholarly journals Exercise training of dogs with myxomatous valve disease

2017 ◽  
Vol 69 (2) ◽  
pp. 325-332 ◽  
Author(s):  
M.A. Valandro ◽  
J.P.E. Pascon ◽  
D.T.P. Pereira ◽  
M.L.A. Mistieri
Keyword(s):  
Heart Rate ◽  
Exercise Training ◽  
High Frequency ◽  
Training Group ◽  
Valve Disease ◽  
Moderate Intensity ◽  
Control Group ◽  
Maximum Heart Rate ◽  
The Time Domain ◽  
And Training

ABSTRACT The present study has the objective of evaluating the effects of exercise training, using moderate intensity walking (60 to 80% of maximum heart rate), from 30 to 50 minutes, three times a week, in alternate days, during eight weeks, on heart rate variability in dogs with myxomatous valve disease (MVD). For that, 20 dogs in stages B1 (1), B2 (14) and C2 (5) of MVD (ACVIM classification) were divided into untrained control group (CG, n=9) and training group (TG, n=11), and assessed at baseline (T0), after four (T1) and eight weeks (T2). Only one B1 and five B2 dogs completed the training program. In the time domain, the rMSSD was greater in TG in T1 (155,5+42,07) and T2 (199,8+83,54) than CG (T1:91,17+35,79 and T2:88,17+57,51). In the frequency domain, the variable High Frequency (HF) increased in TG in T1 (30950+25810) and T2 (40300+33870) when compared to the CG (T1:19090+23210 and T2:18810+22200) and within the group TG in T2 in relation to T0 (29340+20950). The proposed walking protocol is concluded to have increased the rMSSD and HF variables in TG, representing an increase of the parasympathetic tonus, justifying the indication of this therapy in B1 and B2 stages of MVD.

A new method of fluxgate signal extraction

2017 ◽  
Vol 2017 (45) ◽  
pp. 83-89
Author(s):  
A.A. Marusenkov ◽  
Keyword(s):  
High Frequency ◽  
Second Harmonic ◽  
Excitation Frequency ◽  
Low Noise ◽  
Measuring System ◽  
Signal Extraction ◽  
Fluxgate Magnetometer ◽  
New Approach ◽  
Average Value ◽  
The Time Domain

Using dedicated high-frequency measuring system the distribution of the Barkhausen jumps intensity along a reversal magnetization cycle was investigated for low noise fluxgate sensors of various core shapes. It is shown that Barkhausen (reversal magnetization) noise intensity is strongly inhomogeneous during an excitation cycle. In the traditional second harmonic fluxgate magnetometers the signals are extracted in the frequency domain, as a result, some average value of reversal magnetization noises is contributed to the output signals. In order to fit better the noise shape and minimize its transfer to the magnetometer output the new approach for demodulating signals of these sensors is proposed. The new demodulating method is based on information extraction in the time domain taking into account the statistical properties of cyclic reversal magnetization noises. This approach yields considerable reduction of the fluxgate magnetometer noise in comparison with demodulation of the signal filtered at the second harmonic of the excitation frequency.

Experimental Investigation of very High Frequency Slot Antenna on M-60A-1 Tank

1977 ◽  
Author(s):  
D. V. Campbell ◽  
William Kennebeck ◽  
A. Zanella ◽  
Paul Sexton
Keyword(s):  
Experimental Investigation ◽  
High Frequency ◽  
Slot Antenna ◽  
Very High Frequency ◽  
Very High

scholarly journals Benefit of a pharmacist-led intervention for medication management of renal transplant patients: a controlled before-and-after study

2021 ◽  
Vol 12 ◽  
pp. 204062232110052
Author(s):  
Jeremy Chambord ◽  
Lionel Couzi ◽  
Pierre Merville ◽  
Karine Moreau ◽  
Fabien Xuereb ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Immunosuppressive Therapy ◽  
Medication Management ◽  
Intervention Group ◽  
Knowledge Score ◽  
Control Group ◽  
Patient Knowledge ◽  
Transplant Patients ◽  
Before And After ◽  
High Level

Aims: To assess the effect of a pharmacist-led intervention, using Barrows cards method, during the first year after renal transplantation, on patient knowledge about their treatment, medication adherence and exposure to treatment in a French cohort. Methods: We conducted a before-and-after comparative study between two groups of patients: those who benefited from a complementary pharmacist-led intervention [intervention group (IG), n = 44] versus those who did not [control group (CG), n = 48]. The pharmacist-led intervention consisted of a behavioral and educational interview at the first visit (visit 1). The intervention was assessed 4 months later at the second visit (visit 2), using the following endpoints: treatment knowledge, medication adherence [proportion of days covered (PDC) by immunosuppressive therapy] and tacrolimus exposure. Results: At visit 2, IG patients achieved a significantly higher knowledge score than CG patients (83.3% versus 72.2%, p = 0.001). We did not find any differences in treatment exposure or medication adherence; however, the intervention tended to reduce the proportion of non-adherent patients with low knowledge scores. Using the PDC by immunosuppressive therapy, we identified 10 non-adherent patients (10.9%) at visit 1 and six at visit 2. Conclusions: Our intervention showed a positive effect on patient knowledge about their treatment. However, our results did not show any improvement in overall medication adherence, which was likely to be because of the initially high level of adherence in our study population. Nevertheless, the intervention appears to have improved adherence in non-adherent patients with low knowledge scores.

A collision feedback based multiple access control protocol for very high frequency data exchange system in E-navigation

2021 ◽  
pp. 1-16
Author(s):  
Xu Hu ◽  
Bin Lin ◽  
Ping Wang ◽  
Hongguang Lyu ◽  
Tie-Shan Li
Keyword(s):  
Access Control ◽  
High Frequency ◽  
Multiple Access ◽  
Data Exchange ◽  
High Frequency Data ◽  
Frequency Data ◽  
Exchange System ◽  
Very High Frequency ◽  
Time Division ◽  
Very High

Abstract The very high frequency data exchange system (VDES) is promising in promoting electronic navigation (E-navigation) and improving navigation safety. The multiple access control (MAC) protocol is crucial to the transmission performance of VDES. The self-organising time division multiple access (SOTDMA) protocol, as the only access mode given by current recommendations, leads to a high rate of transmission collisions in the traditional automatic identification system (AIS), especially with heavy traffic loads. This paper proposes a novel feedback based time division multiple access (FBTDMA) protocol to address the problems caused by SOTDMA, such that collision of transmissions can be avoided in information transmission among vessels. Simulation results demonstrate that the proposed FBTDMA outperforms the traditional SOTDMA in terms of channel utilisation and throughput, and significantly reduces the transmission collision rate. The study is expected to provide insights into VDES standardisation and E-navigation modernisation.

scholarly journals Measurement of Electrical Properties of Superconducting YBCO Thin Films in the VHF Range

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3360
Author(s):  
Yakir Dahan ◽  
Eldad Holdengreber ◽  
Elichai Glassner ◽  
Oz Sorkin ◽  
Shmuel E. Schacham ◽  
...  
Keyword(s):  
Thin Films ◽  
Theoretical Model ◽  
Quality Factor ◽  
High Frequency ◽  
Unit Length ◽  
Superconducting Thin Films ◽  
Electrical Parameters ◽  
Very High Frequency ◽  
Production Constraints ◽  
Very High

A new measurement technique of electrical parameters of superconducting thin films at the Very High Frequency (VHF) range is described, based on resonators with microstrip (MS) structures. The design of an optimal resonator was achieved, based on a thorough theoretical analysis, which is required for derivation of the exact configuration of the MS. A theoretical model is presented, from which an expression for the attenuation of a MS line can be derived. Accordingly, simulations were performed, and an optimal resonator for the VHF range was designed and implemented. Production constraints of YBa2Cu3O7 (YBCO) limited the diameter of the sapphire substrate to 3″. Therefore, a meander configuration was formed to fit the long λ/4 MS line on the wafer. By measuring the complex input reflection coefficients of a λ/4 resonator, we extracted the quality factor, which is mainly affected by the dielectric and conductor attenuations. The experimental results are well fitted by the theoretical model. The dielectric attenuation was calculated using the quasi-static analysis of the MS line. An identical copper resonator was produced and measured to compare the properties of the YBCO resonator in reference to the copper one. A quality factor of ~6·105 was calculated for the YBCO resonator, three orders of magnitude larger than that of the copper resonator. The attenuation per unit length of the YBCO layer was smaller by more than five orders of magnitude than that of the copper.

Da eine oder mehrere betroffen …

2020 ◽  
Vol 48 (1) ◽  
pp. 47-100
Author(s):  
Melitta Gillmann
Keyword(s):  
High Frequency ◽  
Formal Language ◽  
Subordinate Clause ◽  
Matrix Clause ◽  
Very High Frequency ◽  
Corpus Study ◽  
Causal Relations ◽  
Legal Texts ◽  
The Matrix ◽  
Very High

AbstractBased on a corpus study conducted using the GerManC corpus (1650–1800), the paper sketches the functional and sociosymbolic development of subordinate clause constructions introduced by the subjunctor da ‘since’ in different text genres. In the second half of the 17th and the first half of the 18th century, the da clauses were characterized by semantic vagueness: Besides temporal, spatial and causal relations, the subjunctor established conditional, concessive, and adversative links between clauses. The corpus study reveals that different genres are crucial to the readings of da clauses. Spatial and temporal usages, for example, occur more often in sermons than in other genres. The conditional reading, in contrast, strongly tends to occur in legal texts, where it displays very high frequency. This could be the reason why da clauses carry indexical meaning in contemporary German and are associated with formal language. Over the course of the 18th century, the causal usages increase in all genres. Surprisingly, these causal da clauses tend to be placed in front of the matrix clause despite the overall tendency of causal clauses to follow the matrix clause.

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