Liquid and protein dynamics using a new minimally invasive pleural catheter in rabbits

1992 ◽  
Vol 72 (3) ◽  
pp. 851-857 ◽  
Author(s):  
V. C. Broaddus ◽  
M. Araya
Keyword(s):  
Minimally Invasive ◽  
Flow Rate ◽  
Protein Concentration ◽  
Liquid Flow Rate ◽  
Specific Activity ◽  
Total Radioactivity ◽  
Pleural Space ◽  
Liquid Volume ◽  
Protein Marker ◽  
Pleural Catheter

To obtain continuous access to the pleural space without causing injury, we tested a new transdiaphragmatic pleural catheter for its ability 1) to drain the pleural space without injury and 2) to drain liquid at a rate equal to normal pleural liquid production. In 13 anesthetized rabbits, we opened the abdomen and dissected through the diaphragm to insert a flared-tip catheter into the ventral pleural space on one side and then turned the rabbit prone. In 10 of the rabbits (8 for 6 h, 2 for 24 h), we continuously collected draining pleural liquid, and in 3 rabbits (6 h), we did not open the catheter. We injected radiolabeled albumin intravenously as a protein marker. Terminally, we collected pleural liquid from both pleural spaces and lavaged for total radioactivity. In 14 awake control rabbits without catheters, we measured normal pleural liquid production by the rate of equilibration of radiolabeled albumin from plasma to pleural liquid. We found that, although the percentage of neutrophils was increased on the side with the catheter (54 vs. 1% in control rabbits), the pleural liquid volume, protein concentration, specific activity of albumin, and total radioactivity in the pleural space were the same on the side with the catheter as on the opposite side and in the control rabbits. The liquid flow rate through the catheter over 6 h was 53 +/- 23 microliters/h [0.017 +/- 0.008 (SD) ml.kg-1.h-1], which was not significantly different from the computed rate of normal pleural liquid production in the control rabbits, 49 +/- 14 microliters/h (0.016 +/- 0.004 ml.kg-1.h-1).(ABSTRACT TRUNCATED AT 250 WORDS)

Minimally invasive technique for insertion of ventriculopleural shunt catheters

2013 ◽  
Vol 12 (5) ◽  
pp. 501-504 ◽  
Author(s):  
Marlin Dustin Richardson ◽  
Michael H. Handler
Keyword(s):  
Minimally Invasive ◽  
Late Complications ◽  
Pleural Space ◽  
Invasive Technique ◽  
Distal Catheter ◽  
Cerebrospinal Fluid Diversion ◽  
Small Series ◽  
Space Technique ◽  
Invasive Method ◽  
Pleural Catheter

Object Cerebrospinal fluid diversion to the pleural space has employed various methods to insert the distal catheter into the pleural space. The authors report on a minimally invasive method of pleural catheter insertion that they have developed and have used safely in a small series of patients. Methods Pleural shunt catheters were inserted using a split trochar into the pleural space (technique described in further detail in the article). All cases over the previous 10 years in which this technique was employed were reviewed from the existing electronic medical records. Patient age at insertion, sex, reason for hydrocephalus, early and late complications, valve type, and follow-up were recorded. Results Fourteen shunt procedures performed in 10 patients were identified. Two small pneumothoraces were detected on routine postoperative imaging and required no intervention. There were 3 late mechanical complications, including migration of a catheter out of the pleural space, catheter fracture at the insertion point, and the need for a longer catheter due to the patient's growth. Conclusions The authors describe a safe, minimally invasive method for insertion of pleural shunt catheters along with a series of patients who have undergone placement of a pleural shunt catheter using this method without complication directly attributable to the use of this technique.

Protein egress and entry rates in pleural fluid and plasma in sheep

1984 ◽  
Vol 56 (2) ◽  
pp. 459-463 ◽  
Author(s):  
J. P. Wiener-Kronish ◽  
K. H. Albertine ◽  
V. Licko ◽  
N. C. Staub
Keyword(s):  
Pleural Fluid ◽  
Protein Concentration ◽  
Pleural Cavity ◽  
Specific Activity ◽  
Average Rate ◽  
Pleural Space ◽  
Thoracic Duct Lymph ◽  
Half Time ◽  
Duct Lymph ◽  
Protein Specific Activity

We determined a rate of protein egress from the pleural cavity into thoracic duct lymph in seven anesthetized sheep in whom we had made 10-ml/kg hydrothoraces containing 1% plasma protein labeled with 125I-albumin. The labeled protein left the pleural space at an average rate of 0.02 ml X kg-1 X h-1. In 25 unanesthetized sheep we injected labeled protein intravenously and collected pleural fluid and plasma at intervals up to 48 h. The radioactivity in the sheeps' plasma fell twice as rapidly as the rate observed in humans. The half time for equilibration between plasma and pleural fluid protein specific activity was approximately 6 h. In seven sheep we gave a continuous infusion of tracer protein. In six of these seven sheep we collected superficial cervical lymph. The protein concentration in the lymph was three times that of pleural fluid. The half time for protein specific activity equilibration between plasma and pleural fluid was 5 h and 3–4 h between plasma and superficial cervical lymph. The rate of protein turnover in the pleural space appears to be much slower than previously reported.

Influence of Seeding Conditions on Initial Biofilm Development during the Startup of Anaerobic Fluidized Bed Reactors

1989 ◽  
Vol 21 (4-5) ◽  
pp. 157-165 ◽  
Author(s):  
F. Ehlinger ◽  
J. M. Audic ◽  
G. M. Faup
Keyword(s):  
Fluidized Bed ◽  
Future Development ◽  
Protein Concentration ◽  
Specific Activity ◽  
Fluidized Bed Reactor ◽  
Fluidized Bed Reactors ◽  
Support Material ◽  
Biofilm Development ◽  
Initial Biofilm

The characterization of the biofilm of an anaerobic fluidized-bed reactor was completed under standard conditions. The distribution of the fixed protein concentration depended on the level in the reactor. The protein concentration reached 1520 µg.g−1 of support at the top of the reactor and only 1200 µg.g−1 at the bottom after 504 hours of operation but the specific activity of the biofilm was 33×10−4 µM acetate.h−1.mg−1 proteins at the bottom and only 26×10−4 µM.h−1.mg−1 at the top. The efficiency of a fluidized bed reactor and the composition of the biofilm changed with an increase of the pH from 7 to 8.5 during the seeding of the support material. Future development of the biofilm and the specific activity of the support were affected.

Absorption of oxygen into solutions of polymers

1986 ◽  
Vol 51 (10) ◽  
pp. 2127-2134 ◽  
Author(s):  
František Potůček ◽  
Jiří Stejskal
Keyword(s):  
Mass Transfer ◽  
Aqueous Solutions ◽  
Transfer Coefficient ◽  
Mass Transfer Coefficient ◽  
Flow Rate ◽  
Liquid Flow ◽  
Flow Curve ◽  
Liquid Flow Rate ◽  
Polymer Concentration ◽  
Newtonian Liquids

Absorption of oxygen into water and aqueous solutions of poly(acrylamides) was studied in an absorber with a wetted sphere. The effects of changes in the liquid flow rate and the polymer concentration on the liquid side mass transfer coefficient were examined. The results are expressed by correlations between dimensionless criteria modified for non-Newtonian liquids whose flow curve can be described by the Ostwald-de Waele model.

scholarly journals Effects of water salinity on the foam dynamics for EOR application

2021 ◽  
Author(s):  
Svetlana Rudyk ◽  
Sami Al-Khamisi ◽  
Yahya Al-Wahaibi
Keyword(s):  
Flow Rate ◽  
Liquid Flow ◽  
Apparent Viscosity ◽  
Liquid Flow Rate ◽  
Salinity Range ◽  
Porous System ◽  
Foam Formation ◽  
Total Flow ◽  
Total Flow Rate ◽  
Foam Flow

AbstractFactors limiting foam injection for EOR application are exceptionally low rock permeability and exceedingly high salinity of the formation water. In this regard, foam formation using internal olefin sulfonate is investigated over a wide salinity range (1, 5, 8, 10, and 12% NaCl) through 10 mD limestone. The relationships between pressure drop (dP), apparent viscosity, liquid flow rate, total flow rate, salinity, foam texture, and length of foam drops at the outlet used as an indicator of viscosity are studied. Foaming is observed up to 12% NaCl, compared to a maximum of 8% NaCl in similar core-flooding experiments with 50 mD limestone and 255 mD sandstone. Thus, the salinity limit of foam formation has increased significantly due to the low permeability, which can be explained by the fact that the narrow porous system acts like a membrane with smaller holes. Compared to the increasing dP reported for highly permeable rocks, dP linearly decreases in almost the entire range of gas fraction (fg) at 1–10% NaCl. As fg increases, dP at higher total flow rate is higher at all salinities, but the magnitude of dP controls the dependence of apparent viscosity on total flow rate. Low dP is measured at 1% and 10% NaCl, and high dP is measured at 5, 8, and 12% NaCl. In the case of low dP, the apparent viscosity is higher at higher total flow rate with increasing gas fraction, but similar at two total flow rates with increasing liquid flow rate. In the case of high dP, the apparent viscosity is higher at lower total flow rate, both with an increase in the gas fraction and with an increase in the liquid flow rate. A linear correlation is found between dP or apparent viscosity and liquid flow rate, which defines it as a governing factor of foam flow and can be considered when modeling foam flow.

Numerical Simulation of Gas-Liquid Two-Phase Flows on Wetted Walls

2010 ◽  
Author(s):  
Yoshiyuki Iso ◽  
Xi Chen
Keyword(s):  
Numerical Simulation ◽  
Flow Rate ◽  
Liquid Flow ◽  
Film Flow ◽  
Liquid Flow Rate ◽  
Flow Transition ◽  
Wall Surface ◽  
Two Phase ◽  
Wall Flows ◽  
Rivulet Flow

Gas-liquid two-phase flows on the wall like liquid film flows, which are the so-called wetted wall flows, are observed in many industrial processes such as absorption, desorption, distillation and others. For the optimum design of packed columns widely used in those kind of processes, the accurate predictions of the details on the wetted wall flow behavior in packing elements are important, especially in order to enhance the mass transfer between the gas and liquid and to prevent flooding and channeling of the liquid flow. The present study focused on the effects of the change of liquid flow rate and the wall surface texture treatments on the characteristics of wetted wall flows which have the drastic flow transition between the film flow and rivulet flow. In this paper, the three-dimensional gas-liquid two-phase flow simulation by using the volume of fluid (VOF) model is applied into wetted wall flows. Firstly, as one of new interesting findings in this paper, present results showed that the hysteresis of the flow transition between the film flow and rivulet flow arose against the increasing or decreasing stages of the liquid flow rate. It was supposed that this transition phenomenon depends on the history of flow pattern as the change of curvature of interphase surface which leads to the surface tension. Additionally, the applicability and accuracy of the present numerical simulation were validated by using the existing experimental and theoretical studies with smooth wall surface. Secondary, referring to the texture geometry used in an industrial packing element, the present simulations showed that surface texture treatments added on the wall can improve the prevention of liquid channeling and can increase the wetted area.

New approach to maintaining liquid flow rate stability in national primary standard

2021 ◽  
pp. 101930
Author(s):  
N.I. Mikheev ◽  
V.M. Molochnikov ◽  
D.V. Kratirov ◽  
O.A. Dushina ◽  
A.A. Paereliy ◽  
...  
Keyword(s):  
Flow Rate ◽  
Liquid Flow ◽  
Liquid Flow Rate ◽  
Primary Standard ◽  
New Approach ◽  
National Primary Standard

scholarly journals Experimental Verification of Real-Time Flow-Rate Estimations in a Tilting-Ladle-Type Automatic Pouring Machine

2021 ◽  
Vol 11 (15) ◽  
pp. 6701
Author(s):  
Yuta Sueki ◽  
Yoshiyuki Noda
Keyword(s):  
Real Time ◽  
Molten Metal ◽  
Flow Rate ◽  
Kalman Filters ◽  
Estimation Method ◽  
Estimation Methods ◽  
Liquid Volume ◽  
Model Parameters ◽  
Rate Estimation ◽  
Time Flow

This paper discusses a real-time flow-rate estimation method for a tilting-ladle-type automatic pouring machine used in the casting industry. In most pouring machines, molten metal is poured into a mold by tilting the ladle. Precise pouring is required to improve productivity and ensure a safe pouring process. To achieve precise pouring, it is important to control the flow rate of the liquid outflow from the ladle. However, due to the high temperature of molten metal, directly measuring the flow rate to devise flow-rate feedback control is difficult. To solve this problem, specific flow-rate estimation methods have been developed. In the previous study by present authors, a simplified flow-rate estimation method was proposed, in which Kalman filters were decentralized to motor systems and the pouring process for implementing into the industrial controller of an automatic pouring machine used a complicatedly shaped ladle. The effectiveness of this flow rate estimation was verified in the experiment with the ideal condition. In the present study, the appropriateness of the real-time flow-rate estimation by decentralization of Kalman filters is verified by comparing it with two other types of existing real-time flow-rate estimations, i.e., time derivatives of the weight of the outflow liquid measured by the load cell and the liquid volume in the ladle measured by a visible camera. We especially confirmed the estimation errors of the candidate real-time flow-rate estimations in the experiments with the uncertainty of the model parameters. These flow-rate estimation methods were applied to a laboratory-type automatic pouring machine to verify their performance.

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