scholarly journals Helicobacter pyloriand Its Genome: Lessons from the Treasure Map

1999 ◽  
Vol 13 (3) ◽  
pp. 218-223 ◽  
Author(s):  
Diane E Taylor
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Molecular Mimicry ◽  
Epithelial Tissue ◽  
Functional Studies ◽  
Type Iv ◽  
Genes Encoding ◽  
Conserved Genes ◽  
H Pylori

The availability of the complete genome sequence ofHelicobacter pylori26695 has opened new avenues for research in the molecular biology of this gastric pathogen. The present review gives a general overview ofH pyloriobtained from the complete genome sequence and compares this with data previously obtained from cloning and functional studies ofH pylori. The cagA pathogenicity island of 40 kilobases, which encodes a type IV secretion system, is discussed. The diversity ofH pylorigenomes is well known, yet new data indicate that some aspects of the genome, particularly outer membrane protein genes, are conserved. Genes encoding proteins involved in molecular mimicry between bacterium and gastric epithelial tissue, specifically those encoding Lewis X and Lewis Y antigens, are discussed. The large number of DNA restriction and modification genes and their role inH pyloriinfection are considered. Finally, gene transfer is discussed. The availability of the complete genome sequence ofH pylori26695 and the soon to be available sequence of J99 will speed up and assist in the analysis ofH pylorigenes and their encoded proteins. The genomes of both strains will be useful as references with which otherH pylorigenomes can be compared.

scholarly journals Complete Genome Sequence of Caulobacter crescentus Bacteriophage φCbK

2012 ◽  
Vol 86 (18) ◽  
pp. 10234-10235 ◽  
Author(s):  
Gaël Panis ◽  
Christophe Lambert ◽  
Patrick H. Viollier
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Caulobacter Crescentus ◽  
Content Type ◽  
Functional Studies ◽  
Bacterial Cell Cycle ◽  
Potential Interactions ◽  
Complete Genome Analysis ◽  
Insight Into

φCbK is a B3 morphotype bacteriophage of theSiphoviridaefamily that infectsCaulobacter crescentus, the preeminent model system for bacterial cell cycle studies. The last 4 decades of research with φCbK as a genetic and cytological tool to study the biology of the host warrant an investigation of the phage genome composition. Herein, we report the complete genome sequence of φCbK and highlight unusual features that emerged from its annotation. The complete genome analysis of the φCbK phage provides new insight into its characteristics and potential interactions with itsCaulobacter crescentushost, setting the stage for future functional studies with φCbK.

scholarly journals Complete Genome Sequence of the Polysaccharide-Degrading Rumen Bacterium Pseudobutyrivibrio xylanivorans MA3014

2020 ◽  
Author(s):  
Nikola Palevich ◽  
Paul H. Maclean ◽  
William J. Kelly ◽  
Sinead C. Leahy ◽  
Jasna Rakonjac ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Bacterial Species ◽  
Glycoside Hydrolases ◽  
Rumen Bacterium ◽  
Protein Coding ◽  
Plant Polysaccharides ◽  
Plant Matter ◽  
Genes Encoding

AbstractRuminants are essential for maintaining the global population and managing greenhouse gas emissions. In the rumen, bacterial species belonging to the genera rumen Butyrivibrio and Pseudobutyrivibrio constitute the core bacterial rumen microbiome and are important degraders of plant-derived complex polysaccharides. Pseudobutyrivibrio xylanivorans MA3014 was selected for genome sequencing in order to examine its ability to breakdown and utilize plant polysaccharides. The complete genome sequence of MA3014 is 3.58 Mb, consists of three replicons (a chromosome, chromid and plasmid), has an overall G+C content of 39.6% and encodes 3,265 putative protein-coding genes (PCGs). Comparative pan-genomics of all cultivated and currently available P. xylanivorans genomes has revealed highly open genomes and a strong correlation of orthologous genes within this species of rumen bacteria. MA3014 is metabolically versatile and capable of utilizing a range of simple mono-or oligosaccharides to complex plant polysaccharides such as pectins, mannans, starch and hemicelluloses for growth, with lactate, butyrate and formate as the principal fermentation end-products. The genes encoding these metabolic pathways have been identified and MA3014 is predicted to encode an extensive repertoire of Carbohydrate-Active enZYmes (CAZymes) with 80 Glycoside Hydrolases (GHs), 28 Carbohydrate Esterases (CEs) and 51 Glycosyl Transferases (GTs), that suggest its role as an initiator of primary solubilization of plant matter in the rumen.

scholarly journals The Complete Genome Sequence of Helicobacter pylori Strain G27

2008 ◽  
Vol 191 (1) ◽  
pp. 447-448 ◽  
Author(s):  
David A. Baltrus ◽  
Manuel R. Amieva ◽  
Antonello Covacci ◽  
Todd M. Lowe ◽  
D. Scott Merrell ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Genetic Variation ◽  
Gastric Carcinoma ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Gastric Diseases ◽  
Gram Negative ◽  
H Pylori

ABSTRACT Helicobacter pylori is a gram-negative pathogen that colonizes the stomachs of over half the world's population and causes a spectrum of gastric diseases including gastritis, ulcers, and gastric carcinoma. The H. pylori species exhibits unusually high levels of genetic variation between strains. Here we announce the complete genome sequence of H. pylori strain G27, which has been used extensively in H. pylori research.

scholarly journals Complete Genome Sequence and Annotation of Campylobacter jejuni YH003, Isolated from Retail Chicken

2020 ◽  
Vol 9 (4) ◽  
Author(s):  
Yiping He ◽  
Sue Reed ◽  
Terence P. Strobaugh
Keyword(s):  
Campylobacter Jejuni ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Type Vi Secretion System ◽  
Multidrug Efflux ◽  
Content Type ◽  
Resistance Factors ◽  
Genes Encoding ◽  
Multidrug Efflux System

The complete genome sequence of Campylobacter jejuni YH003, isolated from retail chicken, was determined using PacBio and Illumina technologies. The assembled genome is 1,743,985 bp (G+C content of 30.3%). Genome annotation revealed several genes encoding virulence and antibiotic resistance factors, including a type VI secretion system, cytolethal distending toxins, and a multidrug efflux system.

scholarly journals Complete Genome Sequence of Bacillus vallismortis NBIF-001, a Novel Strain from Shangri-La, China, That Has High Activity against Fusarium oxysporum

2017 ◽  
Vol 5 (48) ◽  
Author(s):  
Xiaoyan Liu ◽  
Yong Min ◽  
Daye Huang ◽  
Ronghua Zhou ◽  
Wei Fang ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Positive Bacterium ◽  
Protein Coding ◽  
Content Type ◽  
Number Of Genes ◽  
Genes Encoding ◽  
Bacillus Vallismortis ◽  
Rna Genes

ABSTRACT Bacillus vallismortis NBIF-001, a Gram-positive bacterium, was isolated from soil in Shangri-La, China. Here, we provide the complete genome sequence of this bacterium, which has a 3,929,787-bp-long genome, including 4,030 protein-coding genes and 195 RNA genes. This strain possesses a number of genes encoding virulence factors of pathogens.

scholarly journals Complete Genome Sequence of Actinomyces hongkongensis HKU8T Isolated from Human Blood

2017 ◽  
Vol 5 (14) ◽  
Author(s):  
Yan-xia Gao ◽  
Yu-yan Zhou ◽  
Ying Xie ◽  
Man Wang ◽  
Shu-juan Wang ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Human Blood ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Human Diseases ◽  
Circular Chromosome ◽  
Content Type ◽  
Genes Encoding

ABSTRACT Members of the genus Actinomyces are strongly associated with human diseases. We present here the complete genome sequence of Actinomyces hongkongensis HKU8T, which consists of one circular chromosome. The strain characteristically contains various genes encoding for enzymes involved in arylamidase utilization.

scholarly journals Complete Genome Sequence of Pseudoalteromonas piscicida Strain DE2-B, a Bacterium with Broad Inhibitory Activity toward Human and Fish Pathogens

2017 ◽  
Vol 5 (33) ◽  
Author(s):  
Gary P. Richards ◽  
David S. Needleman ◽  
Michael A. Watson
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Inhibitory Activity ◽  
Complete Genome ◽  
Antibacterial Properties ◽  
Halophilic Bacterium ◽  
Fish Pathogens ◽  
Content Type ◽  
Multiple Genes ◽  
Genes Encoding

ABSTRACT Pseudoalteromonas piscicida strain DE2-B is a halophilic bacterium which has broad inhibitory activity toward vibrios and other human and fish pathogens. We report the first closed genome sequence for this species, which consists of two chromosomes (4,128,210 and 1,188,838 bp). Annotation revealed multiple genes encoding proteases with potential antibacterial properties.

scholarly journals Complete Genome Sequence of Klebsiella pneumoniae Myophage Mulock

2019 ◽  
Vol 8 (46) ◽  
Author(s):  
Lorna Min ◽  
Lauren Lessor ◽  
Chandler O’Leary ◽  
Rachele Bonasera ◽  
Jason Gill ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Opportunistic Pathogen ◽  
Phage Lambda ◽  
Content Type ◽  
Hospital Acquired Infections ◽  
Genes Encoding ◽  
Hospital Acquired

Klebsiella pneumoniae is an opportunistic pathogen associated with hospital-acquired infections. This report describes the complete genome of the K. pneumoniae myophage Mulock, which appears to be a temperate myophage distantly related to other Klebsiella myophages in morphogenesis genes and is partially syntenic with the canonical Escherichia phage lambda in genes encoding lambda-like functions.

scholarly journals Complete Genome Sequence ofCaulobacter crescentusSiphophage Seuss

2015 ◽  
Vol 3 (5) ◽  
Author(s):  
Jordan M. Sloan ◽  
Jennifer L. Keene ◽  
Jesse L. Cahill ◽  
Eric S. Rasche ◽  
Gabriel F. Kuty Everett
Keyword(s):  
Life Cycle ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Caulobacter Crescentus ◽  
Hypothetical Proteins ◽  
Genes Encoding ◽  
Key Features

Caulobacter crescentusis a water-dwelling bacterium known to have a dimorphic life cycle. Here, we announce the complete genome of Seuss, aC. crescentusicosahedral siphophage, and describe key features. Seuss is unique among phages deposited in GenBank, with genes encoding novel hypothetical proteins composing 45% of its genome.

scholarly journals Complete Genome Sequence of Escherichia coli Phage vB_EcoM_Alf5

2017 ◽  
Vol 5 (20) ◽  
Author(s):  
Laurynas Alijošius ◽  
Eugenijus Šimoliūnas ◽  
Laura Kaliniene ◽  
Rolandas Meškys ◽  
Lidija Truncaitė
Keyword(s):  
Escherichia Coli ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Molecular Level ◽  
Content Type ◽  
E Coli ◽  
Functional Studies ◽  
K 12 ◽  
Escherichia Coli Phage

ABSTRACT Here, we announce the complete genome sequence of the Escherichia coli myophage vB_EcoM_Alf5 belonging to the genus Felixo1virus, whose members have not been comprehensively studied at the molecular level. Phage vB_EcoM_Alf5 infects E. coli K-12-derived laboratory strains and therefore is well suited for functional studies.

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