scholarly journals Diagnosis and Treatment of Neurocysticercosis

2009 ◽  
Vol 2009 ◽  
pp. 1-9 ◽  
Author(s):  
Christina M. Coyle ◽  
Herbert B. Tanowitz

Neurocysticercosis, the infection caused by the larval form of the tapewormTaenia solium, is the most common parasitic disease of the central nervous system and the most common cause of acquired epilepsy worldwide. This has primarily been a disease that remains endemic in low-socioeconomic countries, but because of increased migration neurocysticercosis is being diagnosed more frequently in high-income countries. During the past three decades improved diagnostics, imaging, and treatment have led to more accurate diagnosis and improved prognosis for patients. This article reviews the current literature on neurocysticercosis, including newer diagnostics and treatment developments.

1996 ◽  
Vol 54 (1) ◽  
pp. 94-97 ◽  
Author(s):  
Thiago D. Gonçalves-Coêlho ◽  
Matheus Diniz G. Coelho

Neurocysticercosis is the infection of the central nervous system by the larval form of Taenia solium , the Cysticercus cellulosae. We studied 4011 computerized tomographies performed in TomoHPI Radioimaging Service, Hospital Pedro I, Campina Grande PB, Northern Brazil, since its installation on August 1993 to July 1995. 41 patients were diagnosed as having Cysticercus cerebral infestation, corresponding to an incidence of 1.02%. No cases were related in Campina Grande PB during 1991 according to hospitalizations under prospective payment rates. After this radioimaging service installation, we observed 1.86 cases per month. We conclude that Campina Grande has to be included as an endemic area of neurocysticercosis, needing health service measures to cease the cycle Taenia-Cysticercus, the only way to get rid of such a serious problem.


2018 ◽  
Vol 5 (4) ◽  
pp. 1595
Author(s):  
Vinod Kumar ◽  
Mushir Reyaz ◽  
Shankar Kumar Gupta ◽  
Pawan Kumar

Cysticercosis is an infection with the larval form of the Taenia solium that commonly involves the central nervous system. Isolated muscular involvement is rare with only a handful of cases reported in the literature. We present a case of isolated cysticercosis of the extensor muscles of the forearm that presented a diagnostic challenge. High resolution ultrasound of the forearm helped in the diagnosis and the patient was managed successfully on anti-helminths and anti-inflammatory medications.


1981 ◽  
Vol 55 (3) ◽  
pp. 382-389 ◽  
Author(s):  
W. Eugene Stern

✓ Infestation of the central nervous system (CNS) by the larval form of Taenia solium can be etiological for one or more of several clinicopathological manifestations. Experience gained from treating 18 patients forms the basis for a classification of this disease and for observations upon therapy. Twenty-three surgical procedures in 15 of the 18 patients provide the foundation for comment on operative treatment in management. Whereas most procedures are palliative, eradication of the CNS disease may be achieved in cases of solitary intraventricular cysts. There has been no operative mortality.


2021 ◽  
Vol 14 (6) ◽  
pp. e242322
Author(s):  
Tusharindra Lal ◽  
Surendran Paramasivam ◽  
Badhrinath Jayapal ◽  
Riya Kataria

Cysticercosis is a tropical infection caused by the larval form of Taenia solium and is usually known to affect the central nervous system. We report a young man who presented with a swelling in the neck and was treated with surgical excision and antihelminthics.


2021 ◽  
Vol 9 (1) ◽  
pp. 286-291
Author(s):  
Diya Wilson ◽  
Khayati Moudgil

Neurocysticercosis (NCC) is a rare central nervous system infection that is preventable and is caused by the Taenia solium tapeworm larval stage. This disorder is the world’s most common cause of acquired epilepsy and a significant cause of neurological morbidity. This disease is pleomorphic due to several complex factors such as cysticerci characteristics, stages of development, and many more which leads to difficulties in inaccurate diagnosis and adequate stage-wise care. The introduction of cystidical medications, however, has led to a stronger prognosis of NCC-affected patients with an increase in the patient’s clinical course of the disease. After diagnosis most seizure patients do not experience epilepsy. Since Neurocysticercosis remains a neglected tropical disease, the management, and prevention of T. so ilium transmission and strategies for eradicating NCC from endemic areas should be highlighted and prioritized in global healthcare to minimize the significant burden on healthcare and the economy.


2010 ◽  
Vol 43 (6) ◽  
pp. 647-650 ◽  
Author(s):  
Reynaldo Mendes de Carvalho Junior ◽  
Dorcas Lamounier Costa ◽  
Savyo Carvalho Soares ◽  
Carlos Henrique Nery Costa

INTRODUCTION: Neurocysticercosis is an infection of the human central nervous system caused by the metacestode larvae of Taenia solium. Neurocysticercosis is the most common parasitic disease in developing countries. Epilepsy is the most common clinical manifestation. Difficulties in confirming the diagnosis motivated the evaluation of the enzyme-linked immunosorbent assay on cerebral spinal fluid (CSF). METHODS: Twenty-two patients with NCC and 44 control patients were studied. CSF was analyzed using a commercial ELISA kit developed for NCC. Sensitivity and specificity were measured and a multivariate logistic regression was performed. RESULTS: Sensitivity and specificity of ELISA were 31.8% and 100%, respectively, with accuracy of 77.3%. Only the size of the lesions proved to be important for performance of the test. CONCLUSIONS: The results showed that ELISA contributes to the diagnosis of neurocysticercosis if the result is negative or if the patient has a lesion of 2 cm or more.


2021 ◽  
Author(s):  
Patrick A. Lewis

Abstract Cellular control of vesicle biology and trafficking is critical for cell viability, with disruption of these pathways within the cells of the central nervous system resulting in neurodegeneration and disease. The past two decades have provided important insights into both the genetic and biological links between vesicle trafficking and neurodegeneration. In this essay, the pathways that have emerged as being critical for neuronal survival in the human brain will be discussed – illustrating the diversity of proteins and cellular events with three molecular case studies drawn from different neurological diseases.


Author(s):  
Agnès Fleury ◽  
Edda Sciutto

Neurocysticercosis is a parasitic disease that occurs when cysticerci are installed in the central nervous system. This paper describes the challenge that continues in the treatment of the most severe form of neurocysticercosis that occurs when the parasite is installed outside the parenchyma. The relevance of neuroinflammation control for patient survival and its implications on the effectiveness of the treatment are discussed.


2016 ◽  
Vol 55 (203) ◽  
pp. 29-32
Author(s):  
Mahesh Prakash ◽  
Pankaj Gupta ◽  
Ajay Gulati ◽  
Niranjan Khandelwal

Cysticercus, the larval form of Taenia Solium, a tapeworm, can infest various tissues in the human body. Though central nervous system involvement is the most dramatic form of infestation, several other uncommon sites of has been reported in the literature. One such involvement is that of the musculature. The most easily recalled manifestation of myocysticercus is that in the orbit where the patients present with painful proptosis. However, other less common muscular sites of involvement are documented in case reports. To the best of our knowledge, there are no documented cases of pyriformis muscle infestation with cysticercus. We came across two interesting cases, where imaging established the diagnosis of isolated pyriformis cysticercosis. Follow up after one month of anti-elminthic treatment imaging revealed disappearance of the lesions. Keywords: magnetic resonance imaging,myocysticercosis; pyriformis; ultrasound. | PubMed


2021 ◽  
Vol 20 (5) ◽  
pp. 500-508
Author(s):  
G. V. Pervushin

Despite the enormous incidence of malaria over the past 2 years, complications of this disease from the nervous system are relatively rare.


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