scholarly journals Neonatal Outcomes of Late-Preterm Birth Associated or Not with Intrauterine Growth Restriction

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Cristiane Ortigosa Rocha ◽  
Roberto Eduardo Bittar ◽  
Marcelo Zugaib
Keyword(s):  
Neonatal Intensive Care ◽  
Pulmonary Hemorrhage ◽  
Neonatal Morbidity ◽  
Late Preterm ◽  
Morbidity And Mortality ◽  
Control Group ◽  
Exact Test ◽  
Intrauterine Growth ◽  
Appropriate For Gestational Age ◽  
Singleton Pregnancies

Objective. To compare neonatal morbidity and mortality between late-preterm intrauterine growth-restricted (IUGR) and appropriate-for-gestational-age (AGA) infants of the comparable gestational ages (GAs).Methods. We retrospectively analyzed neonatal morbidity and mortality of 50 singleton pregnancies involving fetuses with IUGR delivered between 34 and 36 6/7 weeks of GA due to maternal and/or fetal indication. The control group consisted of 36 singleton pregnancies with spontaneous preterm delivery at the same GA, in which the infant was AGA. Categorical data were compared between IUGR and AGA pregnancies by analysis and Fisher's exact test. Ordinal measures were compared using the Kruskal-Wallis test.Results. The length of stay of newborns in the nursery, as well as the need for and duration of hospitalization in the neonatal intensive care unit, was longer in the group with IUGR. Transient tachypnea of the newborn or apnea rates did not differ significantly between the IUGR and AGA groups. IUGR infants were found to be at a higher risk of intraventricular hemorrhage. No respiratory distress syndrome, pulmonary hemorrhage or bronchopulmonary dysplasia was observed in either group. The frequency of sepsis, thrombocytopenia and hyperbilirubinemia was similar in the two groups. Hypoglycemia was more frequent in the IUGR group. No neonatal death was observed.Conclusion. Our study showed that late-preterm IUGR infants present a significantly higher risk of neonatal complications when compared to late-preterm AGA infants.

scholarly journals Neonatal Morbidity in Late Preterm Infants Associated with Intrauterine Growth Restriction

2019 ◽  
Vol 7 (21) ◽  
pp. 3592-3595
Author(s):  
Evelina Kreko ◽  
Ermira Kola ◽  
Festime Sadikaj ◽  
Blerta Dardha ◽  
Eduard Tushe
Keyword(s):  
Neonatal Intensive Care ◽  
Birth Asphyxia ◽  
Neonatal Morbidity ◽  
Maternity Hospital ◽  
Late Preterm ◽  
Control Group ◽  
Neonatal Deaths ◽  
Intrauterine Growth ◽  
Appropriate For Gestational Age ◽  
The Difference

AIM: This study aims to compare the neonatal morbidity of Intrauterine growth restricted (IUGR) Late Preterm (LP) babies, to those born Late Preterm but evaluated as Appropriate for Gestational Age (AGA). METHODS: The study is a 2-year prospective one that used data from the Neonatal Intensive Care Unit (NICU) charts of LP neonates born in our tertiary maternity hospital “Koço Gliozheni” in Tirana. Congenital anomalies and genetical syndromes are excluded. Neonatal morbidity of IUGR Late Preterm is compared to those born Late Preterm but evaluated as AGA. OR and CI, 95% is calculated. RESULTS: Out of 336 LP babies treated in NICU, 88 resulted with IUGR and 206 AGA used as a control group. We found significantly higher morbidity in the IUGR group for hypoglycemia, polycythemia, feeding intolerance, birth asphyxia and seizures, secondary sepsis have higher morbidity but the difference is not significant. No differences were found for hyperbilirubinemia in both groups. No neonatal deaths were observed in both groups. CONCLUSION: Our study showed that late preterm IUGR has a significantly higher risk for neonatal morbidity when compared to late preterm AGA babies.

scholarly journals Influence of a Breastfeeding Coaching Program on the Breastfeeding Rates and Neonatal Morbidity in Late Preterm Infants

2020 ◽  
Vol 26 (3) ◽  
pp. 376-384
Author(s):  
Gun Ja Jang
Keyword(s):  
Preterm Infants ◽  
Neonatal Intensive Care ◽  
Neonatal Morbidity ◽  
Late Preterm ◽  
University Hospital ◽  
Control Group ◽  
Late Preterm Infants ◽  
Breastfeeding Rate ◽  
Breastfeeding Rates ◽  
Experimental Group

Purpose: This study aimed to determine the influence of a breastfeeding coaching program (BCP) for mothers of late preterm infants (LPIs) on the breastfeeding rate and neonatal morbidity within 1 month after discharge.Methods: This was a non-randomized quasi-experimental study with a time series design. The participants were 40 LPIs and their mothers who were hospitalized in a neonatal intensive care unit at a university hospital. Nineteen LPIs were assigned to the control group, and 21 to the experimental group. The mothers of the LPIs in the experimental group received the BCP once on the discharge day and then once a week for 1 month. Neonatal morbidity was defined as an outpatient department or emergency room visit due to an LPI's health problem.Results: The breastfeeding rate in the experimental group was significantly higher than in the control group at the fourth week after discharge (<i>x</i><sup>2</sup>=7.17, <i>p</i>=.028). Five and two LPIs in the control group and the experimental group, respectively, visited a hospital due to neonatal jaundice. Neonatal morbidity was not significantly different between the two groups (<i>x</i><sup>2</sup>=1.95, <i>p</i>=.164).Conclusion: The BCP was useful for improving the breastfeeding rates of LPIs and may have potential to reduce neonatal morbidity.

scholarly journals Effects of tactile-kinesthetic stimulation on feeding and weight of moderate and late preterm neonates

2020 ◽  
Author(s):  
Emily Muthoni Nyaga ◽  
Nehad Sabry Basiouny ◽  
Fabian Omoding Esamai ◽  
Gamalat El-Sayed Mansy
Keyword(s):  
Weight Gain ◽  
Underlying Mechanism ◽  
Late Preterm ◽  
Preterm Neonates ◽  
Control Group ◽  
Moderate Pressure ◽  
Feeding Intolerance ◽  
Joint Movement ◽  
Chi Square ◽  
Exact Test

Abstract Background: Owing to immaturity of their body systems, preterm neonates are susceptible to feeding intolerance, slowed growth and long hospitalization periods among others. Tactile-kinesthetic stimulation, a moderate pressure of the skin and joint movement has been widely researched on among preterm neonates; the studies have predominately focused on weight gain and the potential underlying mechanism. This study focuses on effect of tactile-kinesthetic stimulation on amount of feeds, feeding intolerance and weight of moderate and late preterm neonates. Methods: A quasi-experimental study comprising 72 preterm neonates born at 28 to <37 weeks gestation age (GA) was conducted. Subjects were divided into two groups; control and tactile-kinesthetic stimulation (TKS). Neonates in the TKS group received massage for 15 minutes per session; 3 times a day for 10 days while control group had standard nursery care. Neonates’ amount of feeds and signs of feeding intolerance were assessed on days 3, 10, 17, and 23 of life while weight was measured on alternate days stating on day 3 up to day 23. Mann Whitney U test, Student t-test, Chi-square test, and Fisher’s exact test were used to determine whether there was any difference in feeding parameters and weight between TKS and control groups. Results: Although amount of feeds didn’t differ between the groups, TKS group neonates had fewer episodes of feeding intolerance compared to those in control group on the 10 th ( p = .03), 17 th ( p = .00), and 23 th ( p = .00) day of life. Moderate preterm neonates didn’t differ in weight gain however; late preterm neonates in TKS group had significantly more weight gain than the control. Conclusion: Tactile-kinesthetic stimulation reduces feeding intolerance and enhance weight gain in moderate preterm neonates. Key words: Preterm neonates, tactile-kinesthetic stimulation, feeding intolerance, and weight. Trial registration: ClinicalTrials.gov NCT04287322, registered on 27/02/2020. Retrospectively registered.

scholarly journals STUDY OF THE INCIDENCE AND EFFECT OF MECONIUM STAINED AMNIOTIC FLUID ON FETAL MORBIDITY AND MORTALITY OF NEONATES BORN

2021 ◽  
pp. 1-3
Author(s):  
Kajal Kunwar ◽  
Shanti HK Singh
Keyword(s):  
Amniotic Fluid ◽  
Neonatal Death ◽  
Neonatal Morbidity ◽  
Fetal Outcome ◽  
Morbidity And Mortality ◽  
Control Group ◽  
Care Hospital ◽  
Early Neonatal Death ◽  
Meconium Staining ◽  
Meconium Stained Amniotic Fluid

Aims and objectives: Meconium stained amniotic fluid was considered a sign of fetal distress and associated with poor fetal outcome, but others considered physiological phenomena to be meconium passage through the fetus and create environmental threats to the fetus before birth. Such magnitude of different opinions was the object behind taking up this study and the aim was to find out the incidence and effect of meconium in terms of morbidity and mortality. Material and Methods: The present study was undertaken to evaluate the significance of MSAF and its fetal outcome in parturients admitted to a tertiary care hospital between June 2012 to June 2014. Detection of MSAF during delivery and follow-up of mother and baby during hospital stay was done. A total number of 100 cases were studied in each group as a prospective study. Results: The total numbers of deliveries during the study period were 850 of which 100 cases had meconium staining of AF (11.6%). Thin meconium staining was seen in 37 cases (4.35%) and Thick meconium was seen in 63 cases (7.41%). The major neonatal complication was birth asphyxia in MSG (19%) which was more in thick MSG (14%). Neonatal morbidity was more in the newborn with the thick meconium group (36.5%) compared to the thin meconium-stained group (29.7%). Early neonatal mortality was 100% associated with thick MSG. Early neonatal death was 2 in thick MSG and it was due to MAS. Stillbirth was 100% associated with thick MSG and it was 4. Whereas stillbirth in the control group was 1. Perinatal mortality was 6% in MSG that was associated with thick MSG. In the control group, it was 1%. Consistency of meconium has a direct bearing on the fetal outcome. In the thick meconium-stained group, Neonatal morbidity was (in our study group) 23 out of 63 cases. Stillbirth was 4; early neonatal death was 2 out of 63 cases. Whereas in thin MSG neonatal morbidity was 11 out of 37 cases. No stillbirth or neonatal death occurred in thin MSG. Conclusion: Immediate airway management, need for suction, and intubation should be guided by the state of the newborn rather than the presence of meconium. Timely diagnosis and management of amniotic fluid stained with meconium can enhance the fetal outcome. The authors of the current study conclude that MSAF adversely affects the fetal outcome mainly by thick meconium.

A Case-Control Comparison of the Effectiveness of Betamethasone to Prevent Neonatal Morbidity and Mortality in Preterm Twin and Singleton Pregnancies

2008 ◽  
Vol 25 (07) ◽  
pp. 449-453 ◽  
Author(s):  
Leah Battista ◽  
Kim Winovitch ◽  
Pamela Rumney ◽  
Elysia Davis ◽  
Cristiane Hagemann ◽  
...  
Keyword(s):  
Neonatal Morbidity ◽  
Case Control ◽  
Morbidity And Mortality ◽  
Control Comparison ◽  
Singleton Pregnancies

Progesterone Gel and Placebo were Equally Effective in Preventing Preterm Birth Among Women with Preterm Labor

2021 ◽  
Author(s):  
Ylva Vladic Stjernholm ◽  
Tomislav Vladic ◽  
Giovanna Marchini
Keyword(s):  
Preterm Birth ◽  
Preterm Labor ◽  
Neonatal Intensive Care ◽  
Maintenance Treatment ◽  
Controlled Trial ◽  
Neonatal Morbidity ◽  
Control Group ◽  
Pathogen Invasion ◽  
Prolonged Pregnancy ◽  
Randomised Controlled

Abstract Introduction The aim of this trial was to evaluate the effect of maintenance treatment with vaginal progesterone gel compared to placebo in preventing preterm birth after the onset of preterm labor.Methods A randomised controlled trial in Sweden in 2009 − 18. Women with preterm labor were randomized to daily doses of progesterone gel 90 mg (n = 29) or placebo (n = 29) after standard treatment with intravenous tocolytics. Women with intravenous tocolytics alone served as controls.Results The latency to delivery was 58 ± 34 days with progesterone and 64 ± 51 days with placebo (p = 0.83), compared to 2 ± 2 days in the control group (progesterone and placebo vs control p < 0.001). The rate of preterm birth before 34 weeks was 34 % after progesterone and 38 % after placebo (p = 0.34) compared to 100 % in the control group (p < 0.001 respectively). The composite neonatal morbidity (p = 0.65) and neonatal intensive care unit admission (p = 0.12) were comparable between the progesterone and placebo groups, but lower in these groups compared neonates of women in the control group (p < 0.001 respectively). Conclusion Maintenance treatment with progesterone gel and placebo were equally effective in preventing preterm birth among women with preterm labor. Both progesterone and placebo prolonged pregnancy more effectively than intravenous tocolysis alone. We hypothesize, that the acidic gel base reinforced the biochemical barrier at the uterine cervix, which counteracted ascending pathogen invasion and subsequent inflammation and thereby delayed preterm birth. The present results suggest, that non-hormonal agents that reinforce the biochemical cervical barrier can be useful for the prevention of preterm birth in clinical practice.

Risk Factors for Neonatal Morbidity and Mortality Among “Healthy,” Late Preterm Newborns

2006 ◽  
Vol 30 (2) ◽  
pp. 54-60 ◽  
Author(s):  
Carrie K. Shapiro-Mendoza ◽  
Kay M. Tomashek ◽  
Milton Kotelchuck ◽  
Wanda Barfield ◽  
Judith Weiss ◽  
...  
Keyword(s):  
Risk Factors ◽  
Neonatal Morbidity ◽  
Late Preterm ◽  
Morbidity And Mortality ◽  
Preterm Newborns

Left ventricular dimensions, systolic functions, and mass in term neonates with symmetric and asymmetric intrauterine growth restriction

2013 ◽  
Vol 25 (2) ◽  
pp. 301-307 ◽  
Author(s):  
Bahar Cinar ◽  
Ahmet Sert ◽  
Zeynel Gokmen ◽  
Ebru Aypar ◽  
Eyup Aslan ◽  
...  
Keyword(s):  
Gestational Age ◽  
Intrauterine Growth Restriction ◽  
Posterior Wall ◽  
Left Ventricular ◽  
Growth Restriction ◽  
Control Group ◽  
Intrauterine Growth ◽  
Left Ventricular Dimensions ◽  
Appropriate For Gestational Age ◽  
Ventricular Dimensions

AbstractBackground:Previous studies have demonstrated structural changes in the heart and cardiac dysfunction in foetuses with intrauterine growth restriction. There are no available data that evaluated left ventricular dimensions and mass in neonates with symmetric and asymmetric intrauterine growth restriction. Therefore, we aimed to evaluate left ventricular dimensions, systolic functions, and mass in neonates with symmetric and asymmetric intrauterine growth restriction. We also assessed associated maternal risk factors, and compared results with healthy appropriate for gestational age neonates.Methods:In all, 62 asymmetric intrauterine growth restriction neonates, 39 symmetric intrauterine growth restriction neonates, and 50 healthy appropriate for gestational age neonates were evaluated by transthoracic echocardiography.Results:The asymmetric intrauterine growth restriction group had significantly lower left ventricular end-systolic and end-diastolic diameters and posterior wall diameter in systole and diastole than the control group. The symmetric intrauterine growth restriction group had significantly lower left ventricular end-diastolic diameter than the control group. All left ventricular dimensions were lower in the asymmetric intrauterine growth restriction neonates compared with symmetric intrauterine growth restriction neonates (p>0.05), but not statistically significant except left ventricular posterior wall diameter in diastole (3.08±0.83 mm versus 3.54 ±0.72 mm) (p<0.05). Both symmetric and asymmetric intrauterine growth restriction groups had significantly lower relative posterior wall thickness (0.54±0.19 versus 0.48±0.13 versus 0.8±0.12), left ventricular mass (9.8±4.3 g versus 8.9±3.4 g versus 22.2±5.7 g), and left ventricular mass index (63.6±29.1 g/m2versus 54.5±24.4 g/m2versus 109±28.8 g/m2) when compared with the control group.Conclusions:Our study has demonstrated that although neonates with both symmetric and asymmetric intrauterine growth restriction had lower left ventricular dimensions, relative posterior wall thickness, left ventricular mass, and mass index when compared with appropriate for gestational age neonates, left ventricular systolic functions were found to be preserved. In our study, low socio-economic level, short maternal stature, and low maternal weight were found to be risk factors to develop intrauterine growth restriction. To our knowledge, our study is the first to evaluate left ventricular dimensions, wall thicknesses, mass, and systolic functions in neonates with intrauterine growth restriction and compare results with respect to asymmetric or symmetric subgroups.

scholarly journals Clinical outcome of the late preterm infants

2017 ◽  
Vol 10 (3) ◽  
pp. 132
Author(s):  
Lutfun Nahar Begum ◽  
Farzana Ahmed ◽  
Kulsum Haq ◽  
Lima Lisa Mallick
Keyword(s):  
Clinical Outcome ◽  
Neonatal Intensive Care ◽  
Distress Syndrome ◽  
Neonatal Morbidity ◽  
Late Preterm ◽  
Tertiary Level ◽  
Short Term ◽  
Late Preterm Infants ◽  
Preterm Babies ◽  
Level Hospital

<p class="Abstract">The aim of this retrospective study was to evaluate the short-term clinical outcome of late preterm babies (34-36 week) in a tertiary level hospital from January 2013 to December 2014. A total of 3,749 babies were delivered during this period of which 513 were late preterm. Among the late preterm babies, 481 babies were delivered by cesarean section. Admission to the neonatal intensive care unit after birth was needed in case of 66 babies. Higher incidences of complication like jaundice (14.4%), sepsis (6.2%), respiratory distress syndrome (2.9%), transient tachypnea (2.3%) and others were found in comparison to control term babies. Ventilation was required in 11 cases. Late preterm mortality was 1.4%. In conclusion, late prematurity is associated with significant neonatal morbidity and mortality.</p>

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