scholarly journals Modeling the Dynamics of an Epidemic under Vaccination in Two Interacting Populations

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Ibrahim H. I. Ahmed ◽  
Peter J. Witbooi ◽  
Kailash Patidar

We present a model for an SIR epidemic in a population consisting of two components—locals and migrants. We identify three equilibrium points and we analyse the stability of the disease free equilibrium. Then we apply optimal control theory to find an optimal vaccination strategy for this 2-group population in a very simple form. Finally we support our analysis by numerical simulation using the fourth order Runge-Kutta method.

2021 ◽  
Vol 25 (7) ◽  
pp. 1107-1114
Author(s):  
E.I. Akinola ◽  
B.E. Awoyemi ◽  
I.A. Olopade ◽  
O.D. Falowo ◽  
T.O. Akinwumi

In this study, the diarrhoea model is developed based on basic mathematical modelling techniques leading to a system (five compartmental model) of ordinary differential equations (ODEs). Mathematical analysis of the model is then carried out on the uniqueness and existence of the model to know the region where the model is epidemiologically feasible. The equilibrium points of the model and the stability of the disease-free state were also derived by finding the reproduction number. We then progressed to running a global sensitivity analysis on the reproduction number with respect to all the parameters in it, and four (4) parameters were found sensitive. The work was concluded with numerical simulations on Maple 18 using Runge-Kutta method of order four (4) where the values of six (6) parameters present in the model were each varied successively while all other parameters were held constant so as to know the behaviour and effect of the varied parameter on how diarrhoea spreads in the population. The results from the sensitivity analysis and simulations were found to be in sync.


2021 ◽  
Author(s):  
James Kent

<p>GungHo is the mixed finite-element dynamical core under development by the Met Office. A key component of the dynamical core is the transport scheme, which advects density, temperature, moisture, and the winds, throughout the atmosphere. Transport in GungHo is performed by finite-volume methods, to ensure conservation of certain quantaties. There are a range of different finite-volume schemes being considered for transport, including the Runge-Kutta/method-of-lines and COSMIC/Lin-Rood schemes. Additional horizontal/vertical splitting approaches are also under consideration, to improve the stability aspects of the model. Here we discuss these transport options and present results from the GungHo framework, featuring both prescribed velocity advection tests and full dry dynamical core tests. </p>


2021 ◽  
Vol 50 (6) ◽  
pp. 1799-1814
Author(s):  
Norazak Senu ◽  
Nur Amirah Ahmad ◽  
Zarina Bibi Ibrahim ◽  
Mohamed Othman

A fourth-order two stage Phase-fitted and Amplification-fitted Diagonally Implicit Two Derivative Runge-Kutta method (PFAFDITDRK) for the numerical integration of first-order Initial Value Problems (IVPs) which exhibits periodic solutions are constructed. The Phase-Fitted and Amplification-Fitted property are discussed thoroughly in this paper. The stability of the method proposed are also given herewith. Runge-Kutta (RK) methods of the similar property are chosen in the literature for the purpose of comparison by carrying out numerical experiments to justify the accuracy and the effectiveness of the derived method.


Author(s):  
Abhishek Kumar ◽  
Nilam

Abstract In this article, we propose and analyze a time-delayed susceptible–infected–recovered (SIR) mathematical model with nonlinear incidence rate and nonlinear treatment rate for the control of infectious diseases and epidemics. The incidence rate of infection is considered as Crowley–Martin functional type and the treatment rate is considered as Holling functional type II. The stability of the model is investigated for the disease-free equilibrium (DFE) and endemic equilibrium (EE) points. From the mathematical analysis of the model, we prove that the model is locally asymptotically stable for DFE when the basic reproduction number {R_0} is less than unity ({R_0} \lt 1) and unstable when {R_0} is greater than unity ({R_0} \gt 1) for time lag \tau \ge 0. The stability behavior of the model for DFE at {R_0} = 1 is investigated using Castillo-Chavez and Song theorem, which shows that the model exhibits forward bifurcation at {R_0} = 1. We investigate the stability of the EE for time lag \tau \ge 0. We also discussed the Hopf bifurcation of EE numerically. Global stability of the model equilibria is also discussed. Furthermore, the model has been simulated numerically to exemplify analytical studies.


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Junhong Li ◽  
Ning Cui

An SEIR model with vaccination strategy that incorporates distinct incidence rates for the exposed and the infected populations is studied. By means of Lyapunov function and LaSalle’s invariant set theorem, we proved the global asymptotical stable results of the disease-free equilibrium. The sufficient conditions for the global stability of the endemic equilibrium are obtained using the compound matrix theory. Furthermore, the method of direct numerical simulation of the system shows that there is a periodic solution, when the system has three equilibrium points.


2020 ◽  
Author(s):  
Tamer Sanlidag ◽  
Nazife Sultanoglu ◽  
Bilgen Kaymakamzade ◽  
Evren Hincal ◽  
Murat Sayan ◽  
...  

Abstract The present study studied the dynamics of SARS-CoV-2 in Northern-Cyprus (NC) by using real data and a designed mathematical model. The model consisted of two equilibrium points, which were disease-free and epidemic. The stability of the equilibrium points was determined by the magnitude of the basic reproduction number (𝑹𝟎). If 𝑹𝟎 < 1, the disease eventually disappears, if 𝑹𝟎 ≥ 1, the presence of an epidemic is stated. 𝑹𝟎 has been calculated patient zero, with a range of 2.38 to 0.65. Currently, the 𝑹𝟎 for NC was found to be 0.65, indicating that NC is free from the SARS-CoV-2 epidemic.


2020 ◽  
Author(s):  
Tamer Sanlidag ◽  
Nazife Sultanoglu ◽  
Bilgen Kaymakamzade ◽  
Evren Hincal ◽  
Murat Sayan ◽  
...  

Abstract The present study studied the dynamics of SARS-CoV-2 in Northern-Cyprus (NC) by using real data and a designed mathematical model. The model consisted of two equilibrium points, which were disease-free and epidemic. The stability of the equilibrium points was determined by the magnitude of the basic reproduction number (𝑹𝟎). If 𝑹𝟎 < 1, the disease eventually disappears, if 𝑹𝟎 ≥ 1, the presence of an epidemic is stated. 𝑹𝟎 has been calculated patient zero, with a range of 2.38 to 0.65. Currently, the 𝑹𝟎 for NC was found to be 0.65, indicating that NC is free from the SARS-CoV-2epidemic.


Mathematics ◽  
2019 ◽  
Vol 7 (12) ◽  
pp. 1192 ◽  
Author(s):  
Fauzi Mohamed Yusof ◽  
Farah Aini Abdullah ◽  
Ahmad Izani Md. Ismail

In this paper, optimal control theory is applied to a system of ordinary differential equations representing a hantavirus infection in rodent and alien populations. The effect of the optimal control in eliminating the rodent population that caused the hantavirus infection is investigated. In addition, Pontryagin’s maximum principle is used to obtain the necessary condition for the controls to be optimal. The Runge–Kutta method is then used to solve the proposed optimal control system. The findings from the optimal control problem suggest that the infection may be eradicated by implementing some controls for a certain period of time. This research concludes that the optimal control mathematical model is an effective method in reducing the number of infectious in a community and environment.


2013 ◽  
Vol 2013 ◽  
pp. 1-15 ◽  
Author(s):  
Wencai Zhao ◽  
Tongqian Zhang ◽  
Zhengbo Chang ◽  
Xinzhu Meng ◽  
Yulin Liu

SIR epidemic models with distributed delay are proposed. Firstly, the dynamical behaviors of the model without vaccination are studied. Using the Jacobian matrix, the stability of the equilibrium points of the system without vaccination is analyzed. The basic reproduction numberRis got. In order to study the important role of vaccination to prevent diseases, the model with distributed delay under impulsive vaccination is formulated. And the sufficient conditions of globally asymptotic stability of “infection-free” periodic solution and the permanence of the model are obtained by using Floquet’s theorem, small-amplitude perturbation skills, and comparison theorem. Lastly, numerical simulation is presented to illustrate our main conclusions that vaccination has significant effects on the dynamical behaviors of the model. The results can provide effective tactic basis for the practical infectious disease prevention.


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