scholarly journals Study on TCM Syndrome Identification Modes of Coronary Heart Disease Based on Data Mining

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Qi Shi ◽  
Huihui Zhao ◽  
Jianxin Chen ◽  
Xueling Ma ◽  
Yi Yang ◽  
...  

Coronary heart disease (CHD) is one of the most important types of heart disease because of its high incidence and high mortality. TCM has played an important role in the treatment of CHD. Syndrome differentiation based on information from traditional four diagnostic methods has met challenges and questions with the rapid development and wide application of system biology. In this paper, methods of complex network and CHAID decision tree were applied to identify the TCM core syndromes of patients with CHD, and to establish TCM syndrome identification modes of CHD based on biological parameters. At the same time, external validation modes were also constructed to confirm the identification modes.

2013 ◽  
Vol 475-476 ◽  
pp. 1025-1031
Author(s):  
Qi Shi ◽  
You Lin Li ◽  
Hui Hui Zhao ◽  
Jian Xin Chen ◽  
Xin Qiu Wang ◽  
...  

Coronary heart disease (CHD), called Thoracic Obstruction in TCM, is one of the most important types of heart disease for its high incidence and high mortality. The methods of syndrome studies in TCM can not be completely in accordance with that of modern medicine because of the complexity itself. In this paper, we decide to investigate the ability of Decision Tree to predict CHD patients with or without qi stagnation syndrome. Predictions with CHAID Decision Tree (one type of the Decision Trees), we obtained recognition patterns made up of seven biological parameters. The accuracy of this diagnosis pattern was 80.7%, the sensitivity and specificity could reach 72.1% and 83.0%. The ADTree recognition pattern include six biological indicators. The accuracy of this diagnosis pattern was 94.6%, the sensitivity and specificity could reach 100% and 94.3%.


2011 ◽  
Vol 393-395 ◽  
pp. 916-920 ◽  
Author(s):  
Qi Shi ◽  
Hui Hui Zhao ◽  
Jian Xin Chen ◽  
Yi Yang ◽  
Cheng Long Zheng ◽  
...  

Coronary heart disease (CHD), called “thoracic obstruction” in TCM, is one of the most important types of heart disease for its high incidence and mortality. The methods of syndrome studies in TCM can not be completely in accordance with these of modern medicine because of the complexity itself. In this paper, we investigated the ability of Artificial Neural Networks (ANNs) to predict CHD patients with or without qi deficiency syndrome. Predictions with Multilayer Perceptron Neural Network (MPLNN, one type of the ANNS), we obtained recognition patterns made up of eight biological parameters. The accuracy of this recognition pattern was 82.2%, and the accuracy of validation pattern was 80.0%.


2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Siming Li ◽  
Hao Xu

Coronary heart disease (CHD) is the leading cause of death. As the main treatment of CHD, modern medicine has improved dramatically in recent years. Although researches of TCM and integrative medicine on CHD are witnessed encouraging progress in many respects, the role TCM playing in the prevention and treatment of CHD has been unprecedentedly challenged under such circumstance of the very fast development of modern medicine. In order to share mutual complementary advantages of TCM and western medicine, this review summarizes the relatively prominent researches of TCM and integrative medicine on CHD in recent years, and illuminates the issue of the orientation of the further research of integrative medicine on CHD, including (1) original innovation of TCM etiology and pathogenesis, (2) combination of disease and TCM syndrome, (3) biological basis of TCM syndrome of CHD, (4) clinical design and quality control of integrative medicine research, (5) herb-drug interaction, (6) difficulties and hot issues of modern medicine.


2021 ◽  
Vol 14 ◽  
Author(s):  
Chunlai Zhao ◽  
Wenjia Wang ◽  
Kaijing Yan ◽  
He Sun ◽  
Jihong Han ◽  
...  

: The alterations in vascular homeostasis is deeply involved in the development of numerous diseases, such as coronary heart disease, stroke, and diabetic complications. Changes in blood flow and endothelial permeability caused by vascular dysfunction are the common mechanisms for these three types of diseases. The disorders of glucose and lipid metabolism can result in changes of the energy production patterns in endothelium and surrounding cells which may consequently cause local energy metabolic disorders, oxidative stress and inflammatory responses. Traditional Chinese medicine (TCM) follows the principle of the “treatment by the syndrome differentiation”. TCM considers of that coronary heart disease, stroke and diabetes complications all as the type of “Qi deficiency and Blood stasis” syndrome, which mainly happens to the vascular system. Therefore, the common pathogenesis of these three types of diseases suggests the treatment strategy by TCM should be in a close manner and named as “treating different diseases by the same treatment”. Qishen Yiqi dripping pills is a modern Chinese herbal medicine which has been widely used for treatment of patients with coronary heart disease characterized as “Qi deficiency and blood stasis” in China. Recently, many clinical reports have demonstrated the potent therapeutic effects of Qishen Yiqi dripping pills on ischemic stroke and diabetic nephropathy. Based on these reports, we will summarize the clinical applications of Qishen Yiqi dripping pills on coronary heart disease, ischemic stroke and diabetic nephropathy, including the involved mechanisms with basic researches.


1991 ◽  
Vol 68 (3_suppl) ◽  
pp. 1059-1066 ◽  
Author(s):  
Esther R. Greenglass ◽  
Juhani Julkunen

According to research, hostility is a reliable predictor of coronary heart disease. Cook-Medley-defined hostility in particular has been seen as a significant precursor of coronary disease. It is important to specify the kind of hostility measured by the Cook-Medley scale. The present study examined the construct validity of the Cook-Medley scale for a sample of 219 university students in Finland, a country with a high incidence of coronary heart disease. The results supported the interpretation of the Cook-Medley scale primarily as a measure of cynicism and distrust. On the basis of our previous research, a subscale of the Cook-Medley scale was formed. This 9-item scale, a measure of Cynical Distrust, correlated positively with cynicism and negatively with trust. Moreover, the over-all pattern of correlations between the new 9-item factor, cynical distrust, and other variables assessing hostility, anger, and trust, was similar to the one obtained for our previous sample of students. It is suggested that this new 9-item scale is a shorter and more specific alternative to the longer Cook-Medley scale as a measure of cynical distrust.


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