Depression and Anxiety Symptoms Relate to Distinct Components of Pain Experience among Patients with Breast Cancer

Breast cancer is a leading cancer diagnosis among women worldwide, with more than 210,000 new cases and 40,000 deaths per year in the United States. Pain, anxiety, and depression can be significant factors during the course of breast cancer. Pain is a complex experience with sensory, affective, and cognitive dimensions. While depression and anxiety symptoms are relatively common among breast cancer patients, little is known about the relation between these psychiatric factors and distinct components of the pain experience. In the present study 60 females presenting to an NCI-designated Cancer Center with newly diagnosed breast cancer completed the Center for Epidemiological Studies 10-item Depression Scale, the State Instrument of the Spielberger State-Trait Anxiety Inventory, and the McGill Pain Questionnaire. Findings indicate that anxiety and depression are common among newly diagnosed breast cancer patients; furthermore, patients experience an appreciable amount of pain even before oncologic treatment starts. State anxiety serves as a predictor of the sensory dimension of the pain experience, whereas depression serves as a predictor of the affective dimension of the pain experience.

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Usefulness of an original self-completed questionnaire for screening of cancer-related mental disorder in patients with newly diagnosed early breast cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2011.29.27_suppl.267 ◽

2011 ◽

Vol 29 (27_suppl) ◽

pp. 267-267

Author(s):

K. Kawaguchi ◽

S. Tuyuki ◽

E. Y. Yoshitoshi ◽

M. Honda ◽

M. Takase ◽

...

Keyword(s):

Breast Cancer ◽

Anxiety Disorder ◽

Mental Disorder ◽

Sexual Activity ◽

Cancer Patients ◽

Clinical Psychologist ◽

Depression And Anxiety ◽

Newly Diagnosed ◽

Breast Cancer Patients ◽

Psychiatric Intervention

267 Background: Cancer-related mental disorder reduces (e.g., depression and anxiety disorder) not only treatment compliance but also compromises the quality of life of the patient. However, psychiatric intervention at the cancer notification has been barely performed in Japan because Japanese people traditionally tend to have a prejudice against psychiatric consultation and about sexual activity. In order to provide more effective treatment for breast cancer patients, it is necessary to treat cancer-related mental disorder in Japan. Methods: Based on Self-rating Depression Scale, Hamilton's Rating Scale for Depression and Beck Depression Inventory, the questionnaires were modified for Japanese patients by psychiatrists and clinical psychologists of our hospital. We asked newly diagnosed breast cancer patients an original self-completed questionnaire regarding the depression and anxiety disorder between January 2010 and March 2011. This questionnaire consists of 14 questions about depression and anxiety disorder without questions of sexual activity, which has two points each question (maximum total points were 28). We recommended the psychiatric interference by a psychiatrist and the clinical psychologist to all patients with more than 14 points in this questionnaire. Results: We obtained data from 116 patients. No patient refused to answer the questionnaire. 23 patients had higher than 14 points in this questionnaire. Of 23 patients, 9 patients received psychiatric intervention without medication, and four patients received psychotropic medications. Based on the results, we avoided the administration of anticancer agent by intravenous infusion in three patients who had higher than 14 points in the questionnaire. Multivariate analysis revealed that unmarried status is associated with a significantly higher score (OR 16.1; p = 0.013). Conclusions: Our data suggest that our original self-completed questionnaire is useful for the screening of the cancer-related mental disorder in order to provide appropriate therapy to newly diagnosed breast cancer patients.

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Assessment of Anxiety and Depression Among Breast Cancer Patients in Ghana

Journal of Global Oncology ◽

10.1200/jgo.18.37000 ◽

2018 ◽

Vol 4 (Supplement 2) ◽

pp. 99s-99s

Author(s):

K.A. Kyei

Keyword(s):

Breast Cancer ◽

Cancer Treatment ◽

Cancer Patients ◽

Mixed Method ◽

Qualitative Data ◽

Well Being ◽

Breast Cancer Treatment ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Breast Cancer Patients

Background: Cancer of the breast happens to be one of the most important diseases worldwide and in Ghana, accounts for the highest referral at the study site. The treatment of breast cancer has evolved over the years offering patients high rates of survival. What is missing in the literature are studies that focus on determining levels of depression and anxiety and how this assessment will impact treatment outcome for breast cancer patients undergoing radiotherapy. Hence, recognizing a better understanding in this study will promote positive social change in three different ways. First, it will serve the cancer population especially patients undergoing breast cancer treatment to manage depression and anxiety. Second, it will enhance efforts for coping and finally increase the overall quality of life of these patients undergoing treatment. Aim: This study aims to find various interventions for depression and anxiety among breast cancer patients in Ghana. Methods: The author used a mixed method design to gather both quantitative and qualitative data. The qualitative data were an interview with selected working participants whiles the quantitative data were a nonprobabilistic approach using a structured questionnaire. This mixed method was a triangulation that described how the interviews supported and confirmed the responses from the patient participants. There was an evaluation of the relationships with a combination of two modified scales, Patient Health Questionnaire (PHQ) and Depression Anxiety Stress Scale (DASS). The sample consisted of 100 patients between the ages of 20-89, and six professionals with a minimum of five years' work experience. Results: Findings of this study indicated the need intervene through counseling and education on behalf of patients in Ghana as they undergo breast cancer treatment. Age and monthly income of patients were statistically significant in predicting the anxiety and depression among the patients. The R (0.397) value was less than 0.5, which depicted that the alternate hypothesis could be accepted. The independent variables significantly predicted the anxiety and depression. Conclusion: The study illustrates a need to understand how breast cancer patients in Ghana go through treatment with the high impact of anxiety and depression with treatment which affects total well-being and life after treatment. Although interventions and management should be available to breast cancer patients with anxiety and depression undergoing treatment of their coping with the burden of the disease, a striking improvement in the survival of patients could be achieved when proper systems are put in place by the Ministry of Health and the government.

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Hubungan Dukungan Sosial dengan Kecemasan dan Depresi pada Pasien Kanker Payudara di RSU Raden Mattaher Jambi

Jurnal Ilmiah Universitas Batanghari Jambi ◽

10.33087/jiubj.v20i1.786 ◽

2020 ◽

Vol 20 (1) ◽

pp. 1

Author(s):

Yuliana Yuliana ◽

Mustikasari Mustikasari ◽

Feri Fernandes

Keyword(s):

Breast Cancer ◽

Social Support ◽

Cancer Patients ◽

Depression Scale ◽

The United States ◽

Anxiety And Depression ◽

Bivariate Analysis ◽

Data Sampling ◽

Breast Cancer Patients ◽

The Impact

Breast cancer is the most common cancer in woman. In Europen there are approximately 175,000 cases found regarding breast cancer and more than 165,000 patients died if the cancer is not controlled, whereas in the United States 44,000 patients died of breast cancer. According to the Hospital Statistics in the Breast Cancer Hospital Information System, Indonesia is the first rank of the most breast cancer patients which can be found in almost every hospital in Indonesia. The impact of breast cancer on the aspects of bio- psycho- social- spritual in breast cancer patients include anxiety and depression.Unfortunately this study is not commonly carried aut by researchers. One effort to reduce anxiety and depression in breast cancer patients is to provide social support. This study aims to determine the relationship of social support with anxiety and depression in breast cancer patients. The method used is analytic cross- sectional study.Also this study is conducted at Raden Mattaher Hospital in Jambi, with 97 breast cancer patients were picked as participants. Data sampling that is utilised in this study was incidental sampling.The data were colleted by using several methods, such as the Multidemensional Scale of Perceived of Social Support (MSPSS) instrument, and the Hospital Anxiety and depression Scale (HADS), and later those data were analysed with Bivariate Analysis using the Chi Square test. The results showed that the average age of breast cancer patient is 46,57, length of diagnosis is 28,59 months, low education level patient is 68,0%, patient who has merried is 91,8%, unemployed patient is 78,4%, patient who reseived good social support is 54,6%, patient with anxiety is 49,5%, and patient with depression is 50,5%. There is relationship between social support and anxiety in breast cancer patients, with (p:0,000).

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Quantitative analysis of diffusion-weighted imaging in high-risk patients and newly diagnosed breast cancer patients; a systematic review

International Journal of Medicine in Developing Countries ◽

10.24911/ijmdc.51-1538825110 ◽

2019 ◽

pp. 1

Author(s):

Basmah Altuwayjiri

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Quantitative Analysis ◽

High Risk ◽

Cancer Patients ◽

Diffusion Weighted Imaging ◽

Newly Diagnosed ◽

Breast Cancer Patients ◽

High Risk Patients ◽

Risk Patients

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Impact of BRCA1/BRCA2 counseling and testing on newly diagnosed breast cancer patients

The Women s Oncology Review ◽

10.3109/14733400400013055 ◽

2004 ◽

Vol 4 (3) ◽

pp. 237-240

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Newly Diagnosed ◽

Breast Cancer Patients ◽

Counseling And Testing ◽

Brca1 Brca2

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116P Real-world treatment patterns and clinical effectiveness of eribulin in HR+/HER2- metastatic breast cancer patients in the United States

Annals of Oncology ◽

10.1016/j.annonc.2021.03.130 ◽

2021 ◽

Vol 32 ◽

pp. S72

Author(s):

S.S. Mougalian ◽

J. Zhang ◽

J.K. Kish ◽

M.E. Zettler ◽

B.A. Feinberg

Keyword(s):

Breast Cancer ◽

United States ◽

Metastatic Breast Cancer ◽

Cancer Patients ◽

Real World ◽

Metastatic Breast ◽

Clinical Effectiveness ◽

The United States ◽

Treatment Patterns ◽

Breast Cancer Patients

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Prospective comparison of the diagnostic accuracy of 18F-FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of primary breast cancer patients

European Radiology ◽

10.1007/s00330-021-07956-0 ◽

2021 ◽

Author(s):

Nils Martin Bruckmann ◽

Julian Kirchner ◽

Lale Umutlu ◽

Wolfgang Peter Fendler ◽

Robert Seifert ◽

...

Keyword(s):

Breast Cancer ◽

Bone Metastases ◽

Cancer Patients ◽

Bone Scintigraphy ◽

Fdg Pet ◽

Primary Breast Cancer ◽

Whole Body ◽

Newly Diagnosed ◽

Breast Cancer Patients ◽

Initial Staging

Abstract Objectives To compare the diagnostic performance of [18F]FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of primary breast cancer patients. Material and methods A cohort of 154 therapy-naive patients with newly diagnosed, histopathologically proven breast cancer was enrolled in this study prospectively. All patients underwent a whole-body [18F]FDG PET/MRI, computed tomography (CT) scan, and a bone scintigraphy prior to therapy. All datasets were evaluated regarding the presence of bone metastases. McNemar χ2 test was performed to compare sensitivity and specificity between the modalities. Results Forty-one bone metastases were present in 7/154 patients (4.5%). Both [18F]FDG PET/MRI and MRI alone were able to detect all of the patients with histopathologically proven bone metastases (sensitivity 100%; specificity 100%) and did not miss any of the 41 malignant lesions (sensitivity 100%). CT detected 5/7 patients (sensitivity 71.4%; specificity 98.6%) and 23/41 lesions (sensitivity 56.1%). Bone scintigraphy detected only 2/7 patients (sensitivity 28.6%) and 15/41 lesions (sensitivity 36.6%). Furthermore, CT and scintigraphy led to false-positive findings of bone metastases in 2 patients and in 1 patient, respectively. The sensitivity of PET/MRI and MRI alone was significantly better compared with CT (p < 0.01, difference 43.9%) and bone scintigraphy (p < 0.01, difference 63.4%). Conclusion [18F]FDG PET/MRI and MRI are significantly better than CT or bone scintigraphy for the detection of bone metastases in patients with newly diagnosed breast cancer. Both CT and bone scintigraphy show a substantially limited sensitivity in detection of bone metastases. Key Points • [18F]FDG PET/MRI and MRI alone are significantly superior to CT and bone scintigraphy for the detection of bone metastases in patients with newly diagnosed breast cancer. • Radiation-free whole-body MRI might serve as modality of choice in detection of bone metastases in breast cancer patients.

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