scholarly journals Enhancement of VEGF on Axial Vascularization of Nano-HA/Collagen/PLA Composites: A Histomorphometric Study on Rabbits

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Xiao Chang ◽  
Hai Wang ◽  
Zhihong Wu ◽  
Xiaojie Lian ◽  
Fuzhai Cui ◽  
...  
Keyword(s):  
Control Group ◽  
Phase 2 ◽  
Histomorphometric Study ◽  
Group A ◽  
Group B ◽  
Axial Vascularization ◽  
Later Phase ◽  
Experimental Group ◽  
Av Bundle

The aim of this study was to investigate whether the nanohydroxyapatite/collagen/poly(L-lactic acid) (nHAC/PLA) composite is suitable to be compounded with VEGF to enhance the axial vascularization in vivo. Thirty rabbits were divided into 2 groups of 15 animals each. In control group, a nHAC/PLA scaffold slice was vascularized axially by an inserted ligated femoral arteriovenous (AV) bundle in the animal. In experimental group, a slice compounded with VEGF gel was applied. The rabbits were sacrificed at 2 weeks, 6 weeks, and 10 weeks after surgery; the specimens of scaffold slices underwent histomorphometric examination; analysis of the microvessel density (MVD) of both groups was done. The combination with VEGF (Group B) did not enhance the vascularization in early phase (2 and 6 weeks,P>0.05) but worked in later phase (10 weeks,P<0.05). The data of the experiment demonstrated the suitability of the nHAC/PLA composite as carrier for the growth factor VEGF, enabling its sustained release in bioactive form with enough binding efficacy.

scholarly journals Axial Vascularization of Nano-HA/Collagen/PLA Composites by Arteriovenous Bundle

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Hai Wang ◽  
Xiao Chang ◽  
Guixing Qiu ◽  
Fuzhai Cui ◽  
Xisheng Weng ◽  
...  
Keyword(s):  
Autologous Bone Marrow ◽  
Bone Defects ◽  
Phase 2 ◽  
Large Defect ◽  
Group A ◽  
Group B ◽  
Axial Vascularization ◽  
Vascularized Bone ◽  
Av Bundle ◽  
Sufficient Oxygen

In previous studies, nano-hydroxyapatite/collagen/poly(L-lactic acid) (nHAC/PLA) composites have been prepared and confirmed to repair small sized bone defects. However, they are restricted to repair a large defect without sufficient oxygen and nutrition for cell survival. The result of this study confirmed that nHAC/PLA composites could be axially vascularized by being implanted intramuscularly with arteriovenous (AV) bundle (Group A) in the groins of rabbits. The combination with autologous bone marrow (Group B) could not enhance it the vascularization in early phase (2 weeks,P>0.05), but it could enhance in middle and later phases (6 and 10 weeks,P<0.01). It meant that nHAC/PLA could be prefabricated as a vascularized bone substitute for grafting.

EFFECT OF YOGA ON CARDIOVASCULAR EFFICIENCY

2019 ◽  
pp. 12-16
Author(s):  
Brij Bhushan Singh ◽  
Shubi Mirja ◽  
Samiya Husain
Keyword(s):  
Statistical Technique ◽  
Step Test ◽  
Control Group ◽  
Significant Difference ◽  
Post Test ◽  
Group A ◽  
Cardio Vascular ◽  
Level Of Significance ◽  
Group B ◽  
Experimental Group

The purpose of this study was to investigate the effects of yogic practices on cardio-vascular efficiency. Material and methods: Total Forty (40) subject’s boys/girls were selected as the sample of the study through the random sampling and their age ranged between 20 to 25 years from the Department of Physical Education, Aligarh Muslim University, Aligarh. The subjects were divided into two groups comprising 20 subjects in each group, namely group “A” (the experimental group) performs yogic practices (Asanas, Pranayamas and Kriyas) and group “B” (the control group) served as control. Statistical technique: for the assessment of the cardiovascular efficiency through Harvard step test pre and post-test was conducted and t-test was applied for the analysis. Result: revealed that there exist a significant difference between group A and group B, at .05 level of significance. On the basis of the pre and post-test among experimental and control group, experimental group found better than the control group on cardiovascular efficiency and significant result were found in this study.

scholarly journals Ameliorative effects of Spinacia oleracea on sperm morphology, count, and motility by normalizing the obesity-induced oxidative stress in Sprague Dawley rats

2020 ◽  
Vol 14 (03) ◽  
pp. 124-127
Author(s):  
Somia Iqbal ◽  
Noman Sadiq ◽  
Saad Siddiqui ◽  
Hira Iqbal
Keyword(s):  
Sperm Concentration ◽  
Treated Group ◽  
Sperm Parameters ◽  
Control Group ◽  
Sprague Dawley ◽  
Normal Morphology ◽  
Sprague Dawley Rats ◽  
Group A ◽  
Group B ◽  
Experimental Group

Background: Obesity is a prevailing metabolic disorder that affects the functioning of the male reproductive system. Excessive adipose tissue enhances reactive oxygen species generation and is linked with male infertility. Spinach has demonstrated antioxidant effects. The present study was conducted to determine the antioxidant effects of spinach on sperm parameters in obese Sprague Dawley rats. Subjects and methods: This randomized control study was conducted at the animal house of the National Institute of Health Islamabad, Islamic International Medical College, Cosmesurge International Hospital, Rawalpindi, and Apollo lab, Islamabad, Pakistan from April 2016 to March 2017. Forty male Sprague Dawley rats having an age of 8 weeks and weight 160-200g were tagged from number 1 to 40. Every third rat was randomly allocated to control Group A (n=13) and remaining into the Experimental group (n=27). Rats of control Group A was given a standard diet while a high-fat diet was given to Experimental group rats to induce obesity for the duration of six weeks. Weight (g) was measured weekly and obesity was confirmed when rats attain more than 20% weight when compared with that of rats of control Group A. Then, after obesity induction, the experimental group was alienated into the obesity control group (Group B) and spinach treated group (Group C). For sample, rats of Group A and Group B were sacrificed, and the cauda epididymis of each rat was placed in a Petri dish containing normal saline and cut into pieces to allow the release of sperm and then sperm parameters (sperms concentration, motility, and morphology) were recorded under the microscope. Then, spinach (5% hot water extract) along with the persistence of fat diet was administered to Group C for 4 weeks and finally, sperm parameters were measured in this group. Results: Sperm concentration/ml, motility (%), and normal morphology (%) of Group B rats were significantly decreased as compared to Group A rats. However, sperm concentration/ml, motility (%), and normal morphology (%) of Group C (spinach treated group) rats was significantly increased (p<0.001) as compared to Group B (obesity control group) rats after administering spinach. Conclusion: The addition of Spinach in a normal diet regimen restores normal sperm morphology, improves sperm motility and concentration.

scholarly journals Efektivitas Buku Saku PHBS di Sekolah dalam Meningkatkan Perilaku Hidup Bersih dan Sehat

2019 ◽  
Vol 6 (2) ◽  
pp. 46-53
Author(s):  
Muthmainah Farida Hanif ◽  
Mury Ririanty ◽  
Iken Nafikadhini
Keyword(s):  
Health Promotion ◽  
School Children ◽  
Strong Support ◽  
Primary School Children ◽  
Vulnerable Groups ◽  
Control Group ◽  
Healthy Life ◽  
Group A ◽  
Group B ◽  
Experimental Group

AbstractSchool children become one of the most vulnerable groups to health problems due to environmental factors and poor lifestyles, so they need for a strong support from the environment in the formation of Clean and Healthy Behavior (PHBS) among school children. The methods and props used in health promotion need to be given careful attention, so that the material or ingredients can easily accepted, assimilated and absorbed by the target. The PHBS pocketbook in school is one of publication media of health promotion which had been through expert test and late published, but the PHBS pocketbook in school has not done effectiveness test to the target audiences. This study aimed to analyze the effectiveness of PHBS pocketbook in schools in improving knowledge, attitudes and intentions of PHBS in primary school children. This research was a real experimental study used Pretest Posttest design with control group conducted in SDN Krembangan Selatan 10, SDN Perak Barat 6 and SDN Kemayoran 1. The results of this study indicate that the value of knowledge, attitude and intention are better after the intervention had given to the experimental group A through the PHBS pocketbook in school and counseling, as well as experiment group B through the PHBS pocketbook in school, while the control group has the same value because no intervention was done. PHBS pocketbook media in those school proved able to increase knowledge, attitude and intention in clean and healthy life behavior in elementary school children.Keywords: pocketbook, Effectiveness, Behavior, PHBS, School

scholarly journals Effect of Pilates exercise on the level of fatigue, cognition and knee proprioception in the elderly population of 60-80 years

2021 ◽  
Vol 9 (2) ◽  
pp. 3774-3779
Author(s):  
Shradha Santosh Shah ◽  
◽  
Sandhya Wasnik ◽  
Keyword(s):  
Elderly Population ◽  
The Elderly ◽  
Exercise Group ◽  
Control Group ◽  
Significant Difference ◽  
Strengthening Exercises ◽  
Group A ◽  
Randomized Control ◽  
Group B ◽  
Experimental Group

Aim: To evaluate the effect of Pilates exercise on the level of fatigue, cognition and knee proprioception in elderly population (60-80 years). Study design: experimental study; randomized control trial. Method: 40 subjects both male and female of age ranging from 60-80 years (66.578 ± 4.857 in group A and 69.4 ± 5.442 in group B) were assigned in to two groups. The objective of the study was explained, and the subjects were screened based on the inclusion and exclusion criteria. Pre-interventional and post-interventional data analysis was done for FSS, 6MWT, MoCA and KJPS error angle. Group A (Experimental group) received Pilates exercise. Group B (control group) received aerobic and strengthening exercises. Both the groups underwent exercises 3 times a week on alternate days for 6 weeks. Duration of exercise for both groups was 45-60 minutes. Results: Both the groups showed clinically and statistically significant improvement in FSS (p<0.0001 in both groups) 6MWT (p<0.0001 in both groups), MoCA (p<0.001 in both groups) and KJPS scores (p<0.0002 in group A and p<0.0001 in group B) at the end of 6 weeks of treatment. There was no significant difference between the groups for FSS (p=0.7226), 6MWT (p=0.813), MoCA (p=0.416) and KJPS (p=0.6213). Conclusion: A significant improvement were observed in both the groups; which concluded that both the groups are equally effective in improvement of FSS, 6MWT, MoCA and KJPS scores. KEY WORDS: Pilates exercise, elderly population, fatigue, cognition, knee proprioception.

Effectiveness of Spinal Mobilization with Leg Movement Versus McKenzie Back Extension Exercises in Lumbar Radiculopathy

2021 ◽  
Vol 15 (5) ◽  
pp. 1436-1440
Author(s):  
B. Ashraf ◽  
S. Ahmad ◽  
K. Ashraf ◽  
S. Kanwal ◽  
S. Ashraf ◽  
...  
Keyword(s):  
Pain Intensity ◽  
Range Of Motion ◽  
Functional Mobility ◽  
Control Group ◽  
City Hospital ◽  
Lumbar Radiculopathy ◽  
Group A ◽  
Leg Movement ◽  
Group B ◽  
Experimental Group

Background: Lumbar Radiculopathy is characterized as radiating pain along with some sensory and motor deficits in lower back and hip into the leg. Manual therapy techniques like Spinal mobilization with leg movement and McKenzie Extension exercise seems to be effective in treating and managing the symptoms associated with Radiculopathy. Aim: To make comparison between effects of Spinal mobilization with leg Movement versus McKenzie Extension exercise to manage the Lumbar Radiculopathy. Methods: The present Randomized Control Trial included 60 patients of age 28-50 years with Lumbar radiculopathy were grouped into two by sealed envelope method; the first group (A) was Experimental Group, while the other group (B) was the control Group and were selected from City hospital Multan from February 2018 to June 2018. The study participants were requested to complete the protocol for 4 weeks (3 days per week, 30 repetitions in one session). All the subjects were examined before and after the tests, for pain intensity (NPRS), functional Mobility measured by MODI and range of motion by goniometry. Results: Results of the study showed significant decrease in pain intensity on NPRS (P< 0.05) and MODI Scoring (P<0.05) with noticeable improvement in Functions and range of motion measured by Goniometry. (Readings were taken at 1st session and at the end of the completion of the session). Pain was equally reduced in both groups while improvement in MODI scoring and Range of motion was more significant in experimental group (A) with respect to the control group (B). Conclusion: Study showed that both techniques SMWLW and McKenzie Extension Exercises were effective in improving the pain, decreasing the severity and MODI Scoring while SMWLM is more effective in improving range of motion. Keywords: Lumbar Radiculopathy, Spinal mobilization with leg movement, McKenzie Extension Exercises

EVIDENCE FOR EXTENDED MAINTENANCE OF THE CORPUS LUTEUM BY UTERINE INFUSION OF A RECOMBINANT TROPHOBLAST α-INTERFERON (TROPHOBLASTIN) IN SHEEP

1990 ◽  
Vol 127 (3) ◽  
pp. R5-R8 ◽  
Author(s):  
J. Martal ◽  
E. Degryse ◽  
G. Charpigny ◽  
N. Assal ◽  
P. Reinaud ◽  
...  
Keyword(s):  
Secretory Activity ◽  
Control Group ◽  
Interferon Α ◽  
Corpora Lutea ◽  
Group A ◽  
High Doses ◽  
Group B ◽  
High Degree ◽  
Experimental Group ◽  
Immunological Cross Reaction

ABSTRACT Ovine trophoblastin (oTP) is a natural interferon of the class-II interferon-α subfamily. Recombinant ovine trophoblastin (r.oTP), produced by genetic engineering, was purified by anion-exchange HPLC. The product exhibited a high degree of homogeneity (>98%), and similar immunological cross reaction and antiviral activity to natural oTP. Antiluteolytic activity of r.oTP was established by intrauterine injection in two groups of cyclic recipient ewes. Control group A included 10 ewes which received sterile BSA in saline twice daily for 8 days (from day 10-12 of oestrous cycle). Experimental group B included 17 ewes which received 80 μg (4 ewes), 170 μg (8 ewes) or 340 μg (5 ewes) r.oTP daily for 8 days. Maintenance of functional corpora lutea for 1 month or more was observed in 4 out of 5 ewes which received high doses of r.oTP. These results indicate that oTP alone extends luteal secretory activity.

scholarly journals Do Mechanical and Physicochemical Properties of Orthodontic NiTi Wires Remain Stable In Vivo?

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Michał Sarul ◽  
Małgorzata Rutkowska-Gorczyca ◽  
Jerzy Detyna ◽  
Anna Zięty ◽  
Maciej Kawala ◽  
...  
Keyword(s):  
Negative Influence ◽  
Nanoindentation Test ◽  
Control Group ◽  
Physiochemical Properties ◽  
Microscopic Evaluation ◽  
Group A ◽  
Group B ◽  
Niti Wires

Introduction and Aim.Exceptional properties of the NiTi archwires may be jeopardized by the oral cavity; thus its long-term effect on the mechanical and physiochemical properties of NiTi archwires was the aim of work.Material and Methods. Study group comprised sixty 0.016×0.022 NiTi archwires from the same manufacturer evaluated (group A) after the first 12 weeks of orthodontic treatment. 30 mm long pieces cut off from each wire prior to insertion formed the control group B. Obeying the strict rules of randomization, all samples were subjected to microscopic evaluation and nanoindentation test.Results.Both groups displayed substantial presence of nonmetallic inclusions. Heterogeneity of the structure and its alteration after usage were found in groups B and A, respectively.Conclusions.Long-term, reliable prediction of biomechanics of NiTi wires in vivo is impossible, especially new archwires from the same vendor display different physiochemical properties. Moreover, manufacturers have to decrease contamination in the production process in order to minimize risk of mutual negative influence of nickel-titanium archwires and oral environment.

scholarly journals Effectiveness of Early Intervention of Coma Arousal Therapy in Traumatic Head Injury Patients

2012 ◽  
Vol 3 (3) ◽  
pp. 137-142 ◽  
Author(s):  
Mandeep LNU ◽  
Pravin Kumar
Keyword(s):  
Early Intervention ◽  
Head Injury ◽  
Group Analysis ◽  
T Test ◽  
Control Group ◽  
Traumatic Head Injury ◽  
Group A ◽  
Traumatic Head ◽  
Group B ◽  
Experimental Group

ABSTRACT Objective To find out efficacy and benefits of early intervention of coma arousal therapy on coma patients after sustaining traumatic head injury. Materials and methods Thirty comatose patients with traumatic head injury were systematic randomly selected. Both experimental group and control group were having 15 patients each. Patients in experimental group were given coma arousal therapy while those in control group did not receive any coma arousal therapy. Glasgow coma scale (GCS) and coma recovery scale (CRS) were assessed before and after 1 and 2 weeks protocol. Results The independent t-test was used for between the group data analysis. Repeated measure ANOVA and post hoc paired t-test were used in within the group analysis. Group A, mean of GCS on 1st, 7th and 14th day of coma arousal therapy was 3.93 (±1.09), 6.33 (±1.04) and 8.46 (±0.91) respectively and for Group B was 3.93 (±1.27), 4.80 (±1.26) and 5.93 (±1.94) respectively, which showed significant improvement (p < 0.05). Group A, mean of CRS on 1st, 7th and 14th day of coma arousal therapy was 2.06 (±1.03), 4.86 (±1.24) and 9.66 (±1.83) respectively and for Group B was 2.33 (±1.11), 2.93 (±1.09) and 4.73 (±2.18) respectively, which showed significant improvement (p < 0.05). When compared between the groups, experimental group showed significant improvement. Conclusion This is concluded from the result of this study that coma arousal therapy is having significant effect on GCS and CRS in traumatic head injury patients when compared to the patients who did not receive coma arousal therapy. How to cite this article Mandeep, Kumar P. Effectiveness of Early Intervention of Coma Arousal Therapy in Traumatic Head Injury Patients. Int J Head and Neck Surg 2012;3(3): 137-142.

Evaluation of the Effect of Ozonated Plant Oils on the Quality of Osseointegration of Dental Implants Under the Influence of Cyclosporin A: An In Vivo Study

2011 ◽  
Vol 37 (2) ◽  
pp. 247-257 ◽  
Author(s):  
Amany A. El Hadary ◽  
Hala H. Yassin ◽  
Sameh T. Mekhemer ◽  
Julian C. Holmes ◽  
Martin Grootveld
Keyword(s):  
Bone Density ◽  
Cyclosporin A ◽  
Dental Implants ◽  
Immunosuppressive Agents ◽  
Control Group ◽  
Term Administration ◽  
Group A ◽  
Group B

Abstract Immunosuppressive agents have been recognized as factors that induce changes and modifications in bone metabolism. The purpose of this study was to evaluate the effect of ozonated plant extracts (herein termed ozonated oil) under the influence of Cyclosporin A (CsA) on osseointegration. A total of 20 dental implants were placed in 20 rabbit tibiae assigned to Group A or B. CsA was injected at an immunosuppressive dose in Groups A and B as a single-dose treatment. At the day of surgery, Group A received a single topical ozonated oil treatment (0.55 mL) around dental implants; Group B, the control group, received no ozonated oil. Animals were sacrificed after 8 weeks. Radiographs were obtained at implant surgery and on the day of sacrifice. Bone quality was compared between the 2 groups. Radiographically, osseointegration was microscopically evaluated using scanning electron and light microscopies. In ozonated Group A specimens, light microscopic examination demonstrated evidence of more organized mature bone compared with Group B. Within the limits of this study, the results suggest that short-term administration of CsA, when administered with topical ozonated oil, may influence bone density and the quality of dental implant osseointegration. Therefore, topically applied ozonated oil may influence bone density and the quality of osseointegration around dental implants.

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