Virgin Coconut Oil: Remedial Effects on Renal Dysfunction in Diabetic Rats

Renal dysfunction is now a prevalent complication of diabetes mellitus. Therefore, this study was carried out to evaluate the remedial effects of virgin coconut oil (VCO) on renal dysfunction in diabetic rats. Fifteen albino Wistar rats were divided into 3 groups that comprise normal control group (Group I) and diabetic control group (Group II) fed with normal rat chows and a diabetic test group (Group III) fed with 10% VCO diet. Group II and Group III were made diabetic by single intraperitoneal injection of 150 mg/kg of freshly prepared alloxan monohydrate. After 72 hours of alloxan injection, fasting blood glucose was tested to confirm diabetes mellitus. After 3 weeks, the animals were anaesthetized and sacrificed to collect blood samples for renal function analysis. The creatinine, urea, and blood urea nitrogen values of Group II were significantly different from those of Group I and Group III at P<0.001. Also, there was significant difference (P<0.05) in total protein value between Group II (4.42 ± 0.47 mg/dL) and Group I (5.78 ± 0.12 mg/dL) as well as Group III (5.86 ± 0.19 mg/dL), but there was no significant difference between that of Group I and Group III (5.78 ± 0.12 mg/dL and 5.86 ± 0.19 mg/dL, resp.). Thus, VCO is effective in preventing renal damage in diabetic patients.

Download Full-text

Nitric oxide level in the nasal and sinus mucosa after exposure to electromagnetic field

Otolaryngology ◽

10.1016/j.otohns.2005.01.012 ◽

2005 ◽

Vol 132 (5) ◽

pp. 713-716 ◽

Cited By ~ 15

Author(s):

Murat Yariktas ◽

Fehmi Doner ◽

Fehmi Ozguner ◽

Osman Gokalp ◽

Harun Dogru ◽

...

Keyword(s):

Nitric Oxide ◽

Paranasal Sinus ◽

Defense Mechanism ◽

Control Group ◽

Group Iii ◽

Group I ◽

Significant Difference ◽

Group Ii ◽

Sinus Mucosa ◽

Control Group Group

OBJECTIVE: The purpose of this study was to examine the changes in nitric oxide (NO) level in the nasal and paranasal sinus mucosa after exposure radiofrequency electromagnetic fields (EMF). STUDY DESIGN AND SETTING: Thirty male Spraque-Dawley rats were randomly grouped as follows: EMF group (group I; n, 10), EMF group in which melatonin received (group II; n, 10) and the control (sham operated) group (group III; n, 10). Groups I and II were exposed to a 900 MHz. Oral melatonin was given in group II. Control rats (group III) were also placed in the tube as the exposure groups, but without exposure to EMF. At the end of 2 weeks, the rats were sacrificed, and the nasal and paranasal sinus mucosa dissected. NO was measured in nasal and paranasal mucosa. RESULTS: The nasal and paranasal sinus mucosa NO levels of group I were significantly higher than those of the control group (group III) ( P < 0.05). However, there was no statistically significant difference between group II and the control group (group III) regarding NO output ( P > 0.05). CONCLUSION: Exposure to EMF released by mobile phones (900 MHz) increase NO levels in the sinus and nasal mucosa. SIGNIFICANCE: Increased NO levels may act as a defense mechanism and presumably related to tissue damage. In addition, melatonin may have beneficial effect to prevent these changes in the mucosa. (Otolaryngol Head Neck Surg 2005; 132: 713-6.)

Download Full-text

Features of the cervix uteri in women of reproductive age with endometrial polyps and micropolyps

HEALTH OF WOMAN ◽

10.15574/hw.2016.113.108 ◽

2016 ◽

pp. 108-111

Author(s):

T.F. Tatarchuk ◽

◽

D.G. German ◽

Keyword(s):

Reproductive Age ◽

Cervix Uteri ◽

Control Group ◽

Women Of Reproductive Age ◽

Endometrial Polyps ◽

Group Iii ◽

Aggressive Form ◽

Group I ◽

Group Ii ◽

Control Group Group

The article presents the comparative analysis of the state of the cervix in women with endometrial polyps and micropolyps. Patients and methods. The study involved 130 patients aged 18-35 years: 70 patients with endometrial polyps (group I), 30 patients with micropolyps (group II) and 30 patients of the control group (group III). Results. According to the anamnesis of women in the I group were significantly more frequent diseases of the cervix, which corrected physical surgery methods, in particular cryodestruction. In group II, the representatives of these indicators were similar to healthy. Normal colposcopic picture met significantly less frequently in patients and I, and II group. The differences in the incidence of HPV high oncogenic risk in all groups were not statistically significant. Conclusion. Destructive methods used in the detection of any changes in the cervix are often overly aggressive, form scars and contributing to inflamaciones process. In the chain of events leading to the formation of PE, cervical pathology and its correction can take the basic place. Key words: endometrial polyp, micropolyps, chronic endometritis, uterine cervix, colposcopy.

Download Full-text

Immunization of Guineapigs against Ascaris suum

Journal of Helminthology ◽

10.1017/s0022149x00021258 ◽

1960 ◽

Vol 34 (3-4) ◽

pp. 347-348 ◽

Cited By ~ 5

Author(s):

L. F. Taffs

Keyword(s):

Control Group ◽

Group Iii ◽

Successful Attempt ◽

Group I ◽

Third Stage ◽

Previous Infection ◽

Group Ii ◽

Intravenous Inoculation ◽

Subcutaneous Inoculation ◽

Control Group Group

It has been shown that guineapigs can be effectively protected against re-infection by the subcutaneous inoculation of embryonated Ascaris eggs (Soulsby, 1957). The purpose of this communication is to report a successful attempt to immunize guineapigs against a lethal oral challenge dose of eggs by the intravenous inoculation of third stage larvae of A. suum.Three groups, each containing nine guineapigs, were infected with Ascaris as follows: Group I was given 10,000 eggs by mouth. Group II Was inoculated intravenously with 2,000 third stage Ascaris larvae which had been obtained from the lungs of other guineapigs on the sixth day of infection. Both groups were challenged at the same time with 250,000 eggs by mouth, along with a control group (Group III) which had no previous infection. The guineapigs in Group I were re-infected after 18 days and those in Group II after 12 days.

Download Full-text

Dietary Consumption of Virgin Coconut Oil Ameliorates Lipid Profiles in Diabetic Rats

Physiology Journal ◽

10.1155/2014/256236 ◽

2014 ◽

Vol 2014 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

A. M. Akinnuga ◽

S. O. Jeje ◽

O. Bamidele ◽

V. E. Sunday

Keyword(s):

Diabetes Mellitus ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Coconut Oil ◽

Very Low Density Lipoprotein ◽

Low Density ◽

Virgin Coconut Oil ◽

Group Iii ◽

Group I ◽

Group Ii

Virgin coconut oil (VCO) is a saturated fat with promising antidiabetic properties but its ameliorative effect on lipid profiles in diabetics is rarely reported. Therefore, in this study, a total of fifteen (15) male rats weighing 200–250 g were divided into 3 experimental groups (n=5). Group I (control) and Group II (diabetic control group) were fed a normal rat chow while Group III (diabetic test group) was fed a 10% VCO diet for 3 weeks. Group II and Group III were made diabetic by intraperitoneal injection of 150 mg/kg of alloxan. After 72 hours of injection, blood glucose was tested to confirm diabetes mellitus. After 3 weeks, the animals were sacrificed to collect blood samples for lipid profile analysis. The results showed a significant increase in concentrations of triglyceride, total cholesterol, low density lipoprotein, and very low density lipoprotein and decrease in concentration of high density lipoprotein in Group II when compared to Group I. Also, the concentrations of triglyceride, total cholesterol, low density lipoprotein, and very low density lipoprotein except high density lipoprotein significantly reduced in Group III when compared to Group II (P<0.01, 0.001). VCO consumption can be claimed to ameliorate lipid levels in diabetes mellitus.

Download Full-text

The Role of sFas in the Immune Escape Mechanism and Progression of Cancer Larynx

Clinical medicine Ear nose and throat ◽

10.4137/cment.s2565 ◽

2009 ◽

Vol 2 ◽

pp. CMENT.S2565

Author(s):

Amr A El Badry ◽

Ismail Elmofty ◽

Amira Helmy

Keyword(s):

Serum Level ◽

Buffy Coat ◽

Control Group ◽

Group Iii ◽

Soluble Fas ◽

Group I ◽

Significant Difference ◽

Cancer Larynx ◽

The Mean ◽

Group Ii

This work assess serum levels of soluble Fas form (sFas) in patients with different stages of laryngeal squamous cell carcinoma(LSCC) to investigate its prognostic significance. We correlate its levels with the morphological changes of peripheral blood cells via buffy coat examinatin. The study population included 70 patients clinically diagnosed and pathohistologically confirmed LSCC in addition to 20 healthy controls. According to TNM classification 33(47.1%) patients were in stage I (group I) and 24(34.3%) in stage II (group II), 13(18.5%) in stage III (group III). The results revealed that the mean serum level of sFas (pg/ml) in the control group was 51.2, in group I was 66.33, in group II was 81.33 and in group III was 112.45. Statistical analysis of the mean of sFas by ELISA test in the patients' groups in comparison to the control revealed a significant increase of both group II and III in comparison to the control group (P < 0.01) but there was no significant difference (P > 0.05) between group I in comparison to either the control or group II. There was a significant difference (P < 0.05) between group I in comparison to group III. LM examination revealed massive extent of the apoptotic cells in group III when compared to both group I and group II. EM examination of the buffy coat revealed apoptotic changes, mainly in the peripheral blood mononuclear cells (PBMNCs), represented by surface membrane ruffles and blebs with clumped nuclear chromatin and vacuolated cytoplasm. In conclusion, this study may help us to better understand one of the escape mechanisms in cancer larynx. This mechanism is represented by the significant increase in both the serum level of sFas and the morphological apoptotic changes that detected in PBMNCs. Soluble Fas may contribute to the progression of laryngeal cancer. It can be used as an attractive target for anticancer therapy and may be considered as a marker of disease progression and poor prognosis in laryngeal cancer.

Download Full-text

EFFECTS OF TRAINING SIDE HOP OVER BARRIER WITH DUMBELL AND HEXAGON WITH DUMBELL ON LEG STRENGTH AND LEG POWER

JOSSAE Journal of Sport Science and Education ◽

10.26740/jossae.v2n2.p46-50 ◽

2018 ◽

Vol 2 (2) ◽

pp. 46

Author(s):

Nur Akbari ◽

Oce Wiriawan ◽

Nining Widyah Kusnanik

Keyword(s):

Control Group ◽

Percentage Increase ◽

Design Data ◽

Group Iii ◽

Strength Group ◽

Leg Strength ◽

Group I ◽

Significant Difference ◽

Quasi Experimental ◽

Group Ii

This study was conducted at 45 students of SMAN 1 Cerme with aged between 15-16 years old. Students were divided into 3 groups. the type of research used quantitative with quasi-experimental approach. Instruments of this study were test of leg strength and leg power using Leg Dynamometer and Jump MD. The research design used matching only design. Data was anlyzed using ANOVA. The results of the research was found that training program side hop over barrier with dumbell and hexagon with dumbbell significantly increase at leg strength and leg power (Sig. 0.000 <α = 0.05). Group I, Group II and Group III had significant difference (Sig. 0.000 α = 0.005). Percentage increase in leg strength group 1 of 1,80% and leg power of 15,49%. Percentage increase in leg strength group II of 1,68% and a power of 14,27% and whereas in the control group increase in leg strength was 1.67% power at 12.32%.It can be concluded that There was an increase in leg strength and leg power in each group after the training was given. In addition, there were differences among the three groups effects seen improved in leg strength and leg power through ANOVA, where the training side hop over barrier with dumbbell and hexagon with dumbell had increased in leg strength and leg power. But side hop over barrier with dumbbell had more significant increased than hexagon with dumbbell. Key words: Side hop over with barrier dumbell, hexagon with dumbell, leg strength and leg power.

Download Full-text

An in vitro comparative Evaluation of Fracture Strength of Roots Instrumentated with Self-adjusting File and Reciproc Reciprocating File, with and without Obturation

10.5005/jp-journals-10060-0005 ◽

2017 ◽

Vol 1 (1) ◽

pp. 20-25

Author(s):

Pooja Kabra

Keyword(s):

Fracture Strength ◽

Comparative Evaluation ◽

Group Iv ◽

Control Group ◽

Group V ◽

Group Iii ◽

Group I ◽

Significant Difference ◽

Group Ii

ABSTRACT Aim The purpose of this study was to evaluate the fracture strength of roots instrumented with the self-adjusting file (SAF; ReDent-Nova, Ra'anana, Israel) and the Reciproc reciprocating file and that were and were not obturated using the warm vertical lateral compaction technique. Materials and methods In total, 75 mandibular premolar teeth were sectioned at or below the cementoenamel junction to obtain roots 13 mm in length. The roots were balanced with respect to buccolingual and mesiodistal diameters and weight. They were distributed into four experimental groups and one control group (n = 15): No instrumentation (group I), instrumentation with SAF files but no obturation (group II), instrumentation with SAF files and obturated with warm vertical lateral compaction (group III), instrumentation with Reciproc File but no obturation (group IV), and instrumentation with Reciproc File and obturated with warm vertical lateral compaction (group V). AH Plus sealer (Dentsply DeTrey, Konstanz, Germany) was used along with gutta-percha points. One week later, a vertical load was applied to the specimen's canal until fracture occurred. Data were statistically analyzed using one-way analysis of variance (p = 0.05). Results The mean fracture load was 312.83 N for group I, 297.35 N for group II, 359.15 N for group III, 231.51 N for group IV, and 275.81 N for group V. Conclusion The fracture resistances exhibited a statistically significant difference between all the groups. Teeth instrumented by SAF exhibited a better fracture resistance. How to cite this article Tyagi S, Choudhary E, Kabra P, Chauhan R. An in vitro comparative Evaluation of Fracture Strength of Roots Instrumentated with Self-adjusting File and Reciproc Reciprocating File, with and without Obturation. Int J Clin Dent Res 2017;1(1):20-25.

Download Full-text

Influence of Internal Thoracic Artery Harvesting on Sternal Osteoblastic Activity and Perfusion

Diagnostics ◽

10.3390/diagnostics10110921 ◽

2020 ◽

Vol 10 (11) ◽

pp. 921

Author(s):

Sergey Mamchur ◽

Yuri Vecherskii ◽

Tatiana Chichkova

Keyword(s):

Coronary Artery ◽

Internal Thoracic Artery ◽

Bypass Graft ◽

Control Group ◽

Emission Computed Tomography ◽

Osteoblastic Activity ◽

Group Iii ◽

Group I ◽

Significant Difference ◽

Group Ii

The purpose of this study was to assess the sternal osteoblastic activity and perfusion in the early period after a coronary artery bypass graft (CABG) using single-photon emission computed tomography (SPECT) and three-phasic dynamic scintigraphy (3PDS) with 99mTc methylene diphosphonate (MDP). Methods: The study group consisted of 57 male patients that were 57.3 ± 6.6 years of age. Thirty-six of them were randomized into two groups: in group I (n = 18), the internal thoracic artery (ITA) was skeletonized, and in group II (n = 18), the ITA was pedicled. All the patients in groups I and II underwent an off-pump CABG using 1.7 ± 0.3 grafts, including one anastomosis of the ITA to the left anterior descending coronary artery. The control group III (n = 21) consisted of patients that underwent mitral valve repair surgery, in whom the sternotomy without the ITA harvesting was performed. The 3PDS and SPECT of the thorax with 99mTc MDP were performed 2 weeks after surgery. Results: The sternal phosphates uptake in group I was approximately twice as high as in group II and approximately 1.5 times higher than in group III (p < 0.05). The MDP uptake asymmetry after the ITA skeletonization was the same as in the group with both intact ITAs. In contrast, after the pedicled ITA harvesting, the osteoblastic activity of the ipsilateral side of the sternum was lower than in the contralateral one. There was no statistically significant difference in scintillation count in the xiphoid process between groups I and II (p > 0.05); however, we observed a significant difference in the manubrium and body (p < 0.05). Conclusion: The main factor that improved the sternal perfusion after a CABG was the preservation of branches supplying the sternum using the skeletonization technique of ITA harvesting.

Download Full-text

Influence of disinfecting agents on the spatial dimensions of alginate mass impressions

Postępy Higieny i Medycyny Doświadczalnej ◽

10.5604/01.3001.0013.8553 ◽

2020 ◽

Vol 74 ◽

pp. 36-41

Author(s):

Marcin Szerszeń ◽

Michał Tyrajski ◽

Daniel Surowiecki ◽

Wojciech Poniewierski ◽

Bartłomiej Górski

Keyword(s):

Dimensional Stability ◽

Control Group ◽

Group Iii ◽

Group I ◽

Significant Difference ◽

Spatial Dimensions ◽

Group Ii ◽

Large Groups

Disinfection of dental impressions is a compulsory procedure performed in order to break the chain of infection. Disinfectants used for this purpose are divided into two large groups. These are ready-to-use disinfectants applied directly over the surface of the impression in the form of a spray and concentrates, which are used to prepare a solution in which the impressions are immersed for a specific period of time. This study aims to evaluate the influence of disinfectants on spatial dimensions of alginate mass impressions. Ninety cubic impressions were prepared using metal matrixes with external dimensions of 28 x 28 mm. Each impression was measured in two planes. The impressions were divided into three equinumerous sets of 30: Group I was disinfected with Zeta 7 Spray (n = 30), Group II was disinfected with Zeta 7 Solution (n = 30), and the control Group III (n = 30). The dimensions of the samples were measured in two planes after 24 (T1) and 120 (T2) hours. The obtained data was analysed statistically. The dimensions of the samples after 24 and 120 hours in the first group were significantly different from those of the control group and the differences were statistically significant (p <0.05). There was no statistically significant difference between the second and the control group after 24 and 120 hours. Ready-to-use disinfectants influence the dimensional stability of alginate-mass impressions. The time between taking the impression and preparation of the cast should be considered while choosing the disinfecting agent.

Download Full-text

Differences in surface roughness of enamel after whey-extract application and CPP-ACP in post extracoronal-tooth bleaching

Majalah Kedokteran Gigi Indonesia ◽

10.22146/majkedgiind.26859 ◽

2018 ◽

Vol 4 (1) ◽

pp. 15

Author(s):

Afiatul Mukarromah ◽

Irfan Dwiandhono ◽

Dian Noviyanti Agus Imam

Keyword(s):

Surface Roughness ◽

Artificial Saliva ◽

Enamel Surface ◽

Tooth Bleaching ◽

Control Group ◽

Group Iii ◽

Group I ◽

Significant Difference ◽

Group Ii ◽

Bleaching Treatment

Demineralization is a process of partial or full tooth mineral loss which caused by acidic environment, for example the side effect of extracoronal bleaching treatment. Demineralization increases enamel surface roughness which leads plaque accumulation. Whey extract and calcium phosphopeptide-amorphous calcium phophate (CPP-ACP) contain calcium and phosphate that can stop the demineralization through remineralization process. This study aimed to determine the differences of enamel surface roughness after whey extract and CPP-ACP application post- extracoronal bleaching. Experimental laboratory with pre- and post-test control group design was performed on 24 first maxillary premolars which devided into 3 groups. On group I, specimens were immersed in artificial saliva. Specimens in group II were immersed in whey extract meanwhile specimens were immersed in CPP-ACP on group III. Whey extract and CPP-ACP immersions were conducted 10 minutes every 12 hours for 15 days. The enamel surface roughness test was performed twice, after extracoronal bleaching treatment and after 15 days remineralization agent application. This study result indicated significant differences between group I and group II and between group I and group III (p<0.05), but there was no significant difference between group II and group III (p>0.05). This study showed whey extract decreased more enamel surface roughness than CPP-ACP but the difference was not significant statistically. So, whey extract and CPP-ACP showed similar remineralization potential.

Download Full-text