scholarly journals A Comparison between Gadofosveset Trisodium and Gadobenate Dimeglumine for Steady State MRA of the Thoracic Vasculature

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
G. Paul Camren ◽  
Gregory J. Wilson ◽  
Vikram R. Bamra ◽  
Khahn Q. Nguyen ◽  
Daniel S. Hippe ◽  
...  

Purpose. Retrospective comparison between gadofosveset trisodium and gadobenate dimeglumine steady state magnetic resonance angiography (SS-MRA) of the thoracic vasculature at 1.5T using signal-to-noise ratio (SNR) and vessel edge sharpness (ES) as markers of image quality.Materials and Methods. IRB approval was obtained. Twenty separate patients each underwent SS-MRA using high-resolution 3D ECG-triggered coronal IR-TFE at 1.5T approximately 3-4 minutes following 10 or 15 mL gadofosveset or 20 mL gadobenate. ROIs were placed in the right atrium, left ventricle, left atrium, ascending aorta, descending aorta, and right pulmonary artery to estimate SNR. Vessel ES was estimated as 20–80% rise distances from line intensity profiles in the left pulmonary vein, ascending aorta, and descending aorta. Data were analyzed using nonpaired Student’st-test (threshold for significance set atP<0.05).Results. There was no significant difference in mean SNR for the gadofosveset or gadobenate groups (Pvalues: 0.14 to 0.85). There was no significant difference in mean vessel ES for gadofosveset and gadobenate groups (Pvalues: 0.17 to 0.78).Conclusion. High quality thoracic SS-MRA can be achieved with gadobenate dimeglumine, similar to that achieved with the blood pool agent gadofosveset trisodium provided that imaging is initiated quickly (3-4 min) after contrast injection.

2002 ◽  
Vol 80 (11) ◽  
pp. 2030-2036 ◽  
Author(s):  
Charles M Drabek ◽  
Jennifer M Burns

An investigation of the heart morphology of 8 male and 15 female hooded seals (Cystophora cristata) revealed that the heart is proportionately large and the aortic bulb is larger than that reported for most seals. Hooded seals of all ages have large hearts (0.64% of the body mass) and the right ventricle is proportionately longer and more muscular than reported for other seals. The bulb of the ascending aorta shows the large-diameter characteristic of seals capable of making long deep dives, and is constricted to a diameter of less than one-third in the descending aorta. In addition, the ascending aorta has a much greater concentration of elastin fibers than does the descending aorta. In combination with the large right ventricle, these features probably serve to increase lung perfusion during the hooded seal's surface recovery, and to maintain a high blood pressure throughout the cardiac cycle during diving bradycardia. That there was no substantive difference in the heart morphology of pups, yearlings, and adults, suggests that these features are important in the development of diving behavior, and agrees with the rapid behavioral and physiological development of hooded seal neonates.


2001 ◽  
Vol 71 (3) ◽  
pp. 282-286
Author(s):  
Ovidiu Stiru ◽  
Roxana Carmen Geana ◽  
Adrian Tulin ◽  
Raluca Gabriela Ioan ◽  
Victor Pavel ◽  
...  

The purpose of this case presentation is to present a simplified surgical technique when in a patient with acute aortic dissection type A (AAD), aortic arch, and ascending aorta is completely replaced without circulatory arrest. A 67-year old male was presented in our institution with severe chest and back pain at 12 h after the onset of the symptoms. Imaging studies by 3D contrast-enhanced thoracic computed tomography (CT-scan) and transesophageal echocardiography (TEE) revealed ascending aortic dissection towards the aortic arch, which was extending in the proximal descending aorta. We practiced emergency median sternotomy and established cardiopulmonary bypass (CBP) between the right atrium and the right femoral artery with successive cross-clamping of the ascending and descending aorta below the origin of the left subclavian artery (LSA). In normothermic condition without circulatory arrest and with antegrade cerebral perfusion, we replaced the ascending aorta and aortic arch with a four branched Dacron graft. Patient evolution was uneventful, and he was discharged, after fourteen days from the hospital. At a one-year follow-up, 3D CT-scan showed no residual dissection with a well-circulated lumen of the supra-aortic arteries. Using the described surgical approach, CPB was not interrupted, the brain was protected, and hypothermia was no used. This approach made these surgical procedures shorter, and known complications of hypothermia and circulatory arrest are avoided.Acute aortic dissection aortic type A, total arch replacement, normothermia


2021 ◽  
Author(s):  
Yusen Feng ◽  
Pengcheng Ma ◽  
Lijuan Wang ◽  
Guifang Sun ◽  
Bin Liu ◽  
...  

Abstract Objective: This study is designed to explore the dual-source computed tomography (DSCT) imaging manifestations of the origin of three rare pulmonary artery abnormalities, and to improve the understanding and diagnosis of the disease.Methods: Collected 30 cases of patients diagnosed by DSCT with pulmonary artery abnormal origins, and retrospectively analyzed their imaging data and postoperative pathological data.Results: Among the 30 patients with abnormal pulmonary artery origin, 16 patients were with unilateral pulmonary artery absence (UAPA), 8 patients were with anomalous origin of unilateral pulmonary artery (AOPA), and 6 patients were left pulmonary artery suspension (LPAS). The diagnosis rate of DSCT is significantly higher than that of echocardiography. The results of DSCT imaging showed that the inner diameter of the ascending aorta, the aortic arch and the descending aorta of UAPA patients were significantly larger than those of LPAS patients (P<0.05). Compared with AOPA patients, the left pulmonary artery diameter, the ratio of the left main pulmonary artery diameter to the main pulmonary artery diameter, and ratio of the left main pulmonary artery diameter to the right main pulmonary artery diameter were significantly increased in UAPA patients (P<0.05). There was no significant difference in the ratio of the inner diameter of the ascending aorta to the descending aorta in patients with UAPA, AOPA and LPAS. Compared with UAPA patients, AOPA patients had no significant changes in the inner diameter of the main pulmonary artery, the inner diameter of the right main pulmonary artery, and the ratio of the inner diameter of the right main pulmonary artery to the main pulmonary artery.Conclusion: DSCT can be used to diagnose the origin of pulmonary artery abnormalities and distinguish its types.


Author(s):  
Patrizio Lancellotti ◽  
Bernard Cosyns

This chapter considers evaluation of the aorta as a routine part of the standard echocardiographic examination. It looks as TTE as an excellent modality for imaging the aortic root, and in the serial measurement of maximum aortic root diameters, aortic regurgitation evaluation, and timing of elective surgery for several entities. In some patients, the right parasternal long-axis view can provide supplementary information of the ascending aorta. Of major importance for evaluation of the thoracic aorta is the suprasternal view. Although the entire thoracic descending aorta is not well imaged by TTE, the abdominal descending aorta is relatively easily visualized. TEE is safe and can be performed at the bedside. It provides a good visualization of the entire thoracic aorta, with the exception of the distal part of the ascending aorta.


2013 ◽  
Vol 24 (1) ◽  
pp. 143-144 ◽  
Author(s):  
Achyut K Sarkar ◽  
Naveenchandra G Sanjeeva ◽  
Nagesh S Waghmare

AbstractWe report a case of fistula between the descending aorta and the left atrium with associated aortopulmonary window and secundum atrial septal defect. No previous reports of such association have been found in the literature. A 5-month-old infant presented with heart failure from the age of 2 weeks. Echocardiography confirmed the presence of an aorto–left atrial fistula, aortopulmonary window, and atrial septal defect. The diagnosis was additionally supported by computed tomography. The entity aorto–left atrial fistula is rare. It is mostly acquired and usually between the ascending aorta and the right atrium or right ventricle or left ventricle. We do not know about all the associated anomalies, which have implications in management. There is a case report of ascending aorto–left atrial fistula associated with bicuspid aortic valve and anomalous origin of coronaries. Here we are reporting a case of descending aorto–left atrial fistula associated with aortopulmonary window.


2017 ◽  
Vol 59 (4) ◽  
pp. 418-424 ◽  
Author(s):  
Teik C See ◽  
Andrew J Patterson ◽  
Nicholas J Hilliard ◽  
Ed Soh ◽  
Andrew P Winterbottom ◽  
...  

Background Dedicated blood-pool contrast agents combined with optimal angiographic protocols could improve the diagnostic accuracy of thoracic magnetic resonance angiography (MRA). Purpose To assess the clinical utility of Gadofesveset-enhanced imaging and compare an optimized steady-state (SS) sequence against conventional first-pass dynamic multi-phase (DMP) imaging. Material and Methods Twenty-nine patients (17 men, 12 women; mean age = 42.7, age range = 18–72 years) referred for MR thoracic venography were recruited. Imaging was performed on a 1.5T MRI system. A blood-pool contrast agent (Gadofesveset) was administered intravenously. Thirty temporal phases were acquired using DMP. This was immediately followed by a high-resolution SS sequence. Three radiologists in consensus reviewed seven thoracic vascular segments after randomizing the acquisition order. Image quality, stenoses, thromboses, and artifacts were graded using a categorical scoring system. The image quality for both approaches was compared using Wilcoxon’s signed-rank test. McNemar’s test was used to compare the proportions of stenosis grades, thrombus and artifacts. Results SS had significantly better image quality than DMP (3.14 ± 0.73 and 2.92 ± 0.60, respectively; P < 0.001). SS identified fewer stenoses (>50%) than DMP; the differences in stenosis categorizations was statistically significant ( P = 0.013). There was no significant difference in the proportions of vessels with thromboses ( P = 0.617). DMP produced more artifacts than SS (101 versus 85); however, the difference was not statistically significant ( P = 0.073). Conclusion Gadofesveset-enhanced thoracic angiography is clinically feasible. SS imaging produces better image quality and fewer artifacts than conventional DMP imaging.


2007 ◽  
Vol 17 (4) ◽  
pp. 445-447 ◽  
Author(s):  
Kemal Nisli ◽  
Umrah Aydogan ◽  
Turkan Tansel

AbstractWe describe a male infant, seen at the age of 10 days, with a very rare form of vascular ring. The aortic arch was left-sided, but the aorta descended on the right, with a right-sided persistently patent arterial duct associated with interruption of the aortic arch and presence of Abbott’s artery. We performed end-to-side anastomosis of the descending aorta to the ascending aorta, divided the Abbott’s artery and the right-sided arterial duct, and banded the pulmonary trunk. Despite our best efforts, the patient died on the eighth day after the surgical intervention.


2019 ◽  
Author(s):  
Jonas Vanthornhout ◽  
Lien Decruy ◽  
Tom Francart

AbstractEEG-based measures of neural tracking of natural running speech are becoming increasingly popular to investigate neural processing of speech and have applications in audiology. When the stimulus is a single speaker, it is usually assumed that the listener actively attends to and understands the stimulus. However, as the level of attention of the listener is inherently variable, we investigated how it affected neural envelope tracking. Using a movie as a distractor, we varied the level of attention while we estimated neural envelope tracking. We varied the intelligibility level by adding stationary noise. We found a significant difference in neural envelope tracking between the condition with maximal attention and the movie condition. This difference was most pronounced in the right-frontal region of the brain. The degree of neural envelope tracking was highly correlated with the stimulus signal-to-noise ratio, even in the movie condition. This could be due to residual neural resources to passively attend to the stimulus. When envelope tracking is used to objectively measure speech understanding this means that the procedure can be made more enjoyable and feasible by letting participants watch a movie during stimulus presentation.


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