scholarly journals Effect of Piroxicam and/or Ascorbic Acid on Postoperative Pain in Orchidectomised Goats

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Richard Oluchukwu Okafor ◽  
Bolanle Dupe Remi-Adewunmi ◽  
Samuel Tanko Fadason
Keyword(s):  
Ascorbic Acid ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Control Group ◽  
Neck Extension ◽  
Procaine Penicillin ◽  
Numerical Rating ◽  
Shallow Breathing ◽  
Group A ◽  
Group B

The study evaluates effects of varied doses of ascorbic acid and piroxicam on behavioural signs of pain in orchidectomised Savannah Brown goats during their postsurgical pain management. The goats were divided into 6 groups of 3 goats each. Orchidectomy was performed on all animals under sedation with xylazine and linear infiltration with lignocaine. After surgery, varied doses of piroxicam (IM) and ascorbic acid (IV) were administered to the goats: Group A = piroxicam, 5 mg/kg + ascorbic acid, 100 mg/kg; Group B = piroxicam, 5 mg/kg + ascorbic acid, 200 mg/kg; Group C = piroxicam, 10 mg/kg + ascorbic acid, 100 mg/kg; Group D = piroxicam, 5 mg/kg; Group E: ascorbic acid, 100 mg/kg together with antibiotics, procaine penicillin, 20,000 IU/kg + streptomycin, 10 mg/kg (IM); and Group F (control) received only the antibiotics. After surgery, pain intensity was determined in each goat by numerical rating scale. Vocalisation, teeth grinding, rapid and shallow breathing, tail wagging, occasionally bleating, neck extension, and dorsal lip curling were recorded at varying degrees across the experimental groups. The goats in the control group showed the highest degree of behavioural signs of pain. It is concluded that treatment with a combination of piroxicam and ascorbic acid ameliorated pain more than either of the agents in orchidectomised Savannah Brown goats.

Vibration anesthesia during carboxytherapy for cellulite: a study protocol

2022 ◽  
Author(s):  
Adria Yared Sadala ◽  
Érika Patrícia Rampazo ◽  
Richard Eloin Liebano
Keyword(s):  
Pain Intensity ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Control Group ◽  
Trial Registry ◽  
Expected Outcome ◽  
Numerical Rating ◽  
Group A ◽  
Group B ◽  
And Control

Background: To date, there has been no investigation addressing the effects of vibration anesthesia during carboxytherapy. Aim: Investigate the analgesic effect of different vibratory devices during carboxytherapy for the treatment of cellulite. Materials & methods: A total of 78 women between 18 and 49 years of age with cellulite in the gluteal region will be randomly allocated to three groups: Group A (carboxytherapy and vibratory device A), Group B (carboxytherapy and vibratory device B) and control group. Pain intensity will be assessed using a numerical rating scale after each puncture. Expected outcome: Vibration anesthesia is expected to be effective at diminishing the pain intensity caused by carboxytherapy comparison with the control group, with no differences between the vibratory devices. Trial registry: Brazilian Registry of Clinical Trials- ReBEC (RBR-8jcqy7c)

scholarly journals Efficacy of Ultrasonography Guided Erector Spinae Plane Block for Perioperative Analgesia in Percutaneous Nephrolithotomy

2021 ◽  
Vol 8 (13) ◽  
pp. 830-834
Author(s):  
Srinivas Kalabhavi ◽  
Revanasiddappa A Kanagali ◽  
Bhuvanesa Nanjappa ◽  
Ravi Bhat ◽  
Promod Makanavar
Keyword(s):  
Scale Score ◽  
Percutaneous Nephrolithotomy ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Erector Spinae ◽  
Secondary Outcome ◽  
Numerical Rating ◽  
Numerical Rating Scale Score ◽  
Group A ◽  
Group B

BACKGROUND Erector spinae block is a paraspinal, fascial block that targets the ventral, dorsal rami and rami communications of spinal nerves. The present study was conducted to know the efficacy of ultrasound guided erector spinae block (ESP) block in preoperative analgesia among patients with percutaneous nephrolithotomy (PCNL) attending a tertiary care hospital. METHODS The study was carried out on 596 patients from Jan 2015 to Jan 2020 who were indicated for PCNL. They were divided into two groups, group A (ESP = 373) and group B (intravenous-IV analgesia = 273). In the group A (N = 373), after induction of general anaesthesia, ESP block with 0.5 % bupivacaine and 1 / 200,000 epinephrine (single shot) was given at lower thoracic level (T10 - 12) and IV analgesia was given in group B. All patients were monitored for supplemental opioid requirement intraoperatively as assessed by their haemodynamic status (baseline change in heart rate-HR & mean arterial blood pressure-MAP). The primary outcome of the study was consumption of tramadol in 24 hrs. Pain assessment every 2-hour pre- and post-operatively using numerical rating (NR) scale was considered as the secondary outcome. Categorical outcomes were compared between study groups using chi-square test / Fisher's exact test; Pvalue of < 0.05 was considered statistically significant using IBM SPSS. RESULTS Most of them in group A were free of pain for 24 hours postoperatively with numerical rating scale score of < 3 and did not require any postop rescue analgesics. Only 1 patient showed numerical rating scale score of 4 around 16 hrs. after the surgery and was given tramadol. Supplemental opioid analgesic was not required by any of the patients during the entire intraoperative period. CONCLUSIONS ESP block is a favourable technique that results in very good analgesic effect preoperatively and also lessens the use of intravenous opioids and other analgesics. KEYWORDS ESP Block, PCNL Surgery, Tramadol, Kidney Stones

scholarly journals EFFECT OF NADIFLOXACIN PHONOPHORESIS AND PULSED ULTRASOUND IN SUBJECTS WITH ACUTE SINUSITIS- A RANDOMIZED CLINICAL TRIAL

2020 ◽  
Vol 8 (9) ◽  
pp. 1179-1182
Author(s):  
Anil Rachappa Muragod ◽  
◽  
Anil S. Harugop ◽  
Kirti Khemlapure ◽  
Krupa Varahmurty ◽  
...  
Keyword(s):  
Rating Scale ◽  
Numerical Rating Scale ◽  
Mean Difference ◽  
Acute Sinusitis ◽  
P Value ◽  
Pulsed Ultrasound ◽  
Before And After ◽  
Numerical Rating ◽  
Group A ◽  
Group B

Aim: To find effectiveness of nadifloxacin phonophoresis over pulsed ultrasound in acute sinusitis subjects. Methods: Study was approved by Institutional Ethical Committee of KAHER Institute of Physiotherapy, Belagavi.40subjects with acute sinusitis were divided randomly into group A, treated with nadifloxacin phonophoresis and group B, treated with pulsed ultrasound. Subjects were assessed using Sinusitis Symptom Score, Numerical Rating scale and Sino-nasal outcome test-22 before and after 4 days of intervention. Result: For sinusitis symptom measure within the groups, mean difference were 6.16±1.97 and 6.27±1.8 with p-value of 0.001 for both the groups which was significant. For between the groups, p-value was 0.700 which was not significant. For numerical rating scale within the groups, mean difference was 0.37±0.14. and 0.27±0.08 with p-value of 0.001 for both the groups which was significant. For between the groups, p-value of 0.014 which was significant. For Sino nasal outcome test within the groups, mean difference was 16.33±9.55 and 7.50±1.85 with p-value of 0.001 for both the groups which was significant. For between the groups, p-value was 0.001 which was significant. Conclusion: Nadifloxacin phonophoresis was more effective than pulsed ultrasound in acute sinusitis.

Comparison of Analgesic Effect of Levobupivacaine with Dexmedetomidine and Levobupivacaine for Scalp Block before Supratentorial Craniotomy: A Randomized Controlled Trial

2020 ◽  
Vol 103 (10) ◽  
pp. 1028-1035
Keyword(s):  
Postoperative Pain ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Control Group ◽  
Study Group ◽  
Analgesic Requirement ◽  
Supratentorial Craniotomy ◽  
Numerical Rating ◽  
Fentanyl Consumption ◽  
Scalp Block

Background: Craniotomy causes acute and chronic pain. Uncontrolled postoperative pain may lead to adverse events. Perioperative scalp nerves block is not only effective in reducing intraoperative hemodynamic response, but it also reduces postoperative pain and postoperative analgesia requirement. Objective: To compare the benefits of adding dexmedetomidine to levobupivacaine in scalp nerves block before craniotomy for the duration of analgesia in supratentorial craniotomy. Materials and Methods: After approval by the Committee for Research, 50 supratentorial craniotomy patients were randomized into two groups. The control group received 30 mL scalp nerves block with 0.25% levobupivacaine with adrenaline 1:200,000, whereas the study group received 30 mL scalp nerves block with 0.25% levobupivacaine with adrenaline 1:200,000 plus dexmedetomidine 1 mcg/kg. The primary outcome was the time to first analgesic requirement postoperatively. The secondary outcomes included intraoperative fentanyl consumption, verbal numerical rating scale, tramadol consumption, and complications during the first 24 hours postoperatively. Results: Patients in the study group had significantly increase time to the first analgesic requirement in postoperative period and reduced intraoperative fentanyl consumption. The median time to first analgesic requirement was 555 (360 to 1,035) minutes in the study group versus 405 (300 to 520) minutes in the control group (p=0.023). Intraoperative fentanyl consumption 125 (75 to 175) mcg in the study group was significantly lower than 200 (150 to 250) mcg in the control group (p=0.02). The verbal numerical rating scale at 1, 4, 8, 12 and 24 hours postoperatively, tramadol consumption, and complications during the first 24 hours postoperatively were not statistically significant different. Conclusion: Preoperative scalp nerves block with 0.25% levobupivacaine with adrenaline (1:200,000) with dexmedetomidine 1 mcg/kg significantly increased the time to first analgesic requirement and reduced intraoperative fentanyl consumption compared to 0.25% levobupivacaine with adrenaline (1:200,000) without perioperative complications. Keywords: Scalp block, Dexmedetomidine, Post-craniotomy analgesia, Supratentorial tumor, Levobupivacaine

scholarly journals Effect of acupuncture TENS versus conventional TENS on post cesarean section incision pain

2018 ◽  
Vol 7 (9) ◽  
pp. 3738
Author(s):  
Priti A. Mehendale ◽  
Mayur T. Revadkar
Keyword(s):  
Pain Intensity ◽  
Rating Scale ◽  
Control Group ◽  
P Value ◽  
Random Allocation ◽  
Lower Segment Caesarean Section ◽  
Post Operative Pain ◽  
Group A ◽  
Group B ◽  
Pain Rating Scale

Background: There is evidence regarding beneficial use of Transcutaneous Electrical Nerve Stimulation (TENS) on post Lower Segment Caesarean Section (LSCS) incision pain. However, efficacy of different types of TENS following C section pain has not yet been explored adequately.Methods: 96 women who had recently undergone LSCS were included for the study. The subjects were in the age group of 20 to 40 years (25.84±3.96); having pain intensity 4 or more on Numerical Pain Rating Scale (NPRS). They were divided into three groups by random allocation method; namely Group A: Acupuncture (Low/Motor) TENS, Group B: Conventional (High/Sensory) TENS and Group C: Control group. Group A and B received specific type of TENS twice a day for 15 minutes. Control group C did not receive any TENS intervention. All subjects received standard post-operative medications and physiotherapy. Pain intensity was recorded on NPRS pre and post intervention.Results: Both Acupuncture TENS and Conventional TENS significantly decreased post-operative pain intensity as compared to control group (p value <0.0001).Conclusions: Both, acupuncture and conventional TENS are equally effective in reducing post LSCS incision pain at a strong and non-painful intensity.

scholarly journals Influence of non-steroidal anti-inflammatory drugs on the inflammatory sonographic features in erosive hand osteoarthritis: an intervention study

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Qun Xia Xu ◽  
Ruth Wittoek
Keyword(s):  
Rating Scale ◽  
Numerical Rating Scale ◽  
Randomized Study ◽  
Power Doppler ◽  
Doppler Signal ◽  
Control Group ◽  
Hand Osteoarthritis ◽  
Synovial Proliferation ◽  
Numerical Rating ◽  
Power Doppler Signal

Abstract Objective The aim was to examine whether inflammatory US features in erosive hand OA patients change when discontinuing intake of NSAIDs before US examination in a non-randomized study. Methods Patients (n = 99) were allocated to the NSAIDs or control group according to their intake at baseline. US was performed at baseline (T0) and 2 weeks after discontinuation of NSAIDs (T1). Inflammatory features (i.e. synovial proliferation, effusion and power Doppler signal) were scored using a semi-quantitative scale (from zero to three). Pain levels were scored on a numerical rating scale. Binomial mixed models were fitted for US features, and odds ratios of having a US score of at least two vs at most one for synovial proliferation and effusion, and zero vs at least one for power Doppler were calculated. Results At baseline, both groups [NSAIDs group (n = 47) vs control group (n = 52)] were comparable for numerical rating scale pain, disease duration, number of radiographically affected joints, BMI and US baseline data, but not for age (P = 0.005). At T1, more synovial proliferation and power Doppler signal was seen compared with T0 in the NSAIDs group (P = 0.018 and 0.031, respectively). However, the interaction term time*NSAIDs was not found to be significant for any variable. The numerical rating scale pain at T1 was higher compared with baseline, although statistically non-significant. Conclusion No significant changes in inflammatory US features were seen in patients with erosive hand OA after withdrawal of NSAIDs for 2 weeks. This study suggests that an NSAID-free period is not necessary before assessing inflammatory disease activity in erosive hand OA.

scholarly journals The effects of a novel pilates exercise prescription method on people with non-specific unilateral musculoskeletal pain: a randomised pilot trial

2016 ◽  
Vol 25 (4) ◽  
pp. 201-206
Author(s):  
Augustine Joshua Devasahayam ◽  
Doreen Ren Yan Ho ◽  
Elsa Yee Sum Leung ◽  
Ming Rong Goh ◽  
Patricia Koh
Keyword(s):  
Musculoskeletal Pain ◽  
Rating Scale ◽  
Exercise Prescription ◽  
Numerical Rating Scale ◽  
Pilot Trial ◽  
Neuromuscular Control ◽  
Secondary Outcome ◽  
Patient Specific ◽  
Control Group ◽  
Numerical Rating

Background: Pain alters the neuromuscular activation and results in altered movement adaptations. A new exercise prescription method proposes that we can restore the neuromuscular control by rehabilitating the deficient neural drive through Pilates exercises. This is done by identifying the postural control deficits using single-leg tests such as hopping, half squats and heel raises. The aim of this study was to find out if this method of prescribing exercises results in clinically relevant outcomes. Methods: Fifteen patients with chronic non-specific low back pain with unilateral musculoskeletal pain were recruited. Following consent, all patients were randomly assigned either to perform gym or Pilates-based individualised exercises once weekly for six weeks. The primary outcome was to measure the pain intensity using a 0–10 numerical rating scale. The secondary outcome measures were: the global perceived effect scale (GPE; 0–10), the patient-specific functional scale (PSFS; the patient-generated measure of disability) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC; the condition-specific measure of disability). Results: There were statistically significant differences noted after intervention within the control group in the numerical rating scale ( P=0.041), GPE ( P=0.024), PSFS ( P=0.039) and within the experimental group in the WOMAC ( P=0.008), GPE ( P=0.007) and PSFS ( P=0.007). However, as there were clinically significant baseline differences, the within-group difference could be due to regression to the mean. There were no statistically significant results between the two groups after intervention. Conclusion: This new prescription method for Pilates-based exercises may improve disability and global perception of recovery. However, the outcomes are not different from a regular gym-based exercise programme.

Assessment of pain, care burden, depression level, sleep quality, fatigue and quality of life in the mothers of children with cerebral palsy

2019 ◽  
Vol 23 (3) ◽  
pp. 483-494 ◽  
Author(s):  
Ilknur Albayrak ◽  
Ayten Biber ◽  
Ahmet Çalışkan ◽  
Funda Levendoglu
Keyword(s):  
Sleep Quality ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Control Group ◽  
Care Burden ◽  
Sf 36 ◽  
Numerical Rating ◽  
Depression Level ◽  
Pain Care

The aim of this study were to evaluate pain, care burden, depression level, sleep quality, fatigue and quality of life (QoL) among a group of mothers of children with cerebral palsy (CP) and to compare their results with a group of healthy controls. The study involved 101 mothers who had children with CP and 67 mothers who had a healthy child as the control group. Pain, care burden, depression level, sleep quality, fatigue and QoL of all the participants were evaluated by the numerical rating scale, the Zarit care burden scale (ZCBS), the beck depression inventory (BDI), the Pittsburgh sleep quality index (PSQI), the checklist individual strength (CIS) and the short form-36 (SF-36), respectively. Numerical rating scale value was 3.57 ± 2.96 in the patient group. When the two groups were compared, the CP group showed higher scores for ZCBS, BDI, PSQI, total CIS and SF-36 subscales of general health and vitality whereas the scores for role physical, role emotional, mental health and mental component summary were found to be lower in the patients, compared to the control group. Reducing caregiving burden of the mothers’ by other family members and increasing psychosocial supports may help improve the mother’s health status.

scholarly journals Effectiveness of the quadriceps strengthening exercise on pain and functional ability of the women with Osteoarthritis (OA)

2021 ◽  
Vol 8 (9) ◽  
pp. 1-6
Author(s):  
Absar Ahmed Qureshi ◽  
◽  
Shadia Hamoud Alshahrani ◽  
Premalatha Paulsamy ◽  
Krishnaraju Venkatesan ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Functional Ability ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Exercise Group ◽  
Control Group ◽  
Timed Up And Go ◽  
Strengthening Exercise ◽  
Study Results ◽  
Numerical Rating

A Quasi experimental design was adopted for this study to find out the effectiveness of quadriceps strengthening exercise program on pain and functional ability of women with knee osteoarthritis (OA). Fifty women with OA were selected in which first 25 women were enrolled in the control group and second 25 women were allotted in the exercise group. Assessments were performed at baseline and at 8 weeks. The functional ability was assessed using the Timed Up and Go (TUG) test and Numerical Rating Scale (NRS) was used to assess the pain level .For the exercise group, quadriceps strengthening exercises were taught and asked the patients to follow the exercise schedule for 8 weeks. The study results show that the pain and functional abilty scores were improved in the exercise group and the difference was statistically significant (p<0.001). The study concluded that a simple quadriceps strengthening exercise programme can significantly improve self reported knee pain and functional ability among women with Knee osteoarthritis. Keywords: Osteoarthritis, Pain, Functional Ability, Exercise, Quadriceps strengthening, Timed Up and Go (TUG) test, Numerical Rating Scale (NRS)

scholarly journals STIMULASI KUTANEUS LEBIH EFEKTIF MENURUNKAN NYERI DISMENORE PADA REMAJA DIBANDINGKAN DENGAN KUNYIT ASAM

2018 ◽  
Vol 7 (2) ◽  
pp. 143
Author(s):  
Natalia Devi Oktarina ◽  
Suwanti Suwanti ◽  
M. Imron Rosyidi
Keyword(s):  
Rating Scale ◽  
Numerical Rating Scale ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Purposive Sampling ◽  
Group Design ◽  
Numerical Rating

Nyeri dismenore adalah nyeri di daerah panggul akibat menstruasi dan produksi zat prostaglandin yang membuat dinding rahim berkontraksi dan pembuluh darah sekitarnya terjepit (kontriksi) yang menimbulkan iskemi jaringan. Penanganan nyeri dismenore dapat dilakukan dengan nonfarmakologis diantaranya dengan pemberian minuman kunyit asam dan stimulasi kutaneus. Penelitian ini untuk mengetahui perbedaan efektivitas pemberian kunyit asam yang baisa dikonsumsi remaja dengan pemberian stimulasi kutaneusterhadap penurunan intensitas nyeri dismenore pada siswi remaja putri. Penelitian ini menggunakan desain penelitian quasy eksperiment dengan rancangan pretest-posttest with control group design. Pengambilan sampel dengan cara purposive sampling. Besarnya sampel adalah 40 remaja di Desa Candirejo Kabupaten Semarang. Instrumen penelitiannya berupa lembar observasi nyeri Numerical Rating Scale. Analisis data menggunakan uji statistik t-test independent. Hasil penelitian melalui uji statistik t-test independent menunjukkan nilai p-value 0,002  yang artinya ada perbedaan efektivitas pemberian kunyit asam dan stimulasi kutaneus terhadap penurunan intensitas nyeri haid dengan rata-rata penurunan skala nyeri lebih tinggi pada stimulasi kutaneus. Kesimpulannya adalah stimulasi kutaneus lebih efektif menurunkan skala nyeri dismenore pada remaja putri.Berdasarkan dari hasil penelitian yang dilakukan diharapkan intervensi stimulasi kutaneus dapat diterapkan dan diaplikasikan sebagai intervensi baru bagi remaja ataupun masyarakat untuk mengatasi dismenore. Kata kunci      : nyeri dismenore, kunyit asam, stimulasi kutaneus

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