scholarly journals Pharmacological and Ethnomedicinal Overview of Heritiera fomes: Future Prospects

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Imran Mahmud ◽  
Md Khirul Islam ◽  
Sanjib Saha ◽  
Apurba Kumar Barman ◽  
Md Mustafizur Rahman ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Anticancer Activities ◽  
Mangrove Plant ◽  
River Deltas ◽  
Traditional Health ◽  
Heritiera Fomes ◽  
Health Practitioners ◽  
Important Medicinal Plant

Mangrove plants are specialized woody plants growing in the swamps of tidal-coastal areas and river deltas of tropical and subtropical parts of the world. They have been utilized for medicinal and other purposes by the coastal people over the years. Heritiera fomes Buch. Ham. (family: Sterculiaceae) commonly known as Sundari (Bengali) is a preeminent mangrove plant occurring in the Sundarbans forest located in the southern part of Bangladesh and adjoining West Bengal province of India. The plant has applications in traditional folk medicine as evidenced by its extensive use for treating diabetes, hepatic disorders, gastrointestinal disorders, goiter, and skin diseases by the local people and traditional health practitioners. A number of investigations indicated that the plant possesses significant antioxidant, antinociceptive, antihyperglycemic, antimicrobial, and anticancer activities. Phytochemical analyses have revealed the presence of important chemical constituents like saponins, alkaloids, glycosides, tannins, steroids, flavonoids, gums, phytosterols, and reducing sugars. The present study is aimed at compiling information on phytochemical, biological, pharmacological, and ethnobotanical properties of this important medicinal plant, with a view to critically assess the legitimacy of the use of this plant in the aforementioned disorders as well as providing directions for further research.

scholarly journals Potential Antimicrobial and Anticancer Activities of an Ethanol Extract from Bouea macrophylla

Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1996 ◽  
Author(s):  
Ngoc Hong Nguyen ◽  
Thuy Trang Nguyen ◽  
Phu Cuong Ma ◽  
Qui Thanh Hoai Ta ◽  
Thuc-Huy Duong ◽  
...  
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Shigella Flexneri ◽  
Folk Medicine ◽  
Antibacterial Properties ◽  
Ethanol Extract ◽  
Anticancer Activities ◽  
Ic50 Values ◽  
Bacteria And Fungi ◽  
Hct116 Cells

Bouea macrophylla is a tree widely grown throughout South East Asia. It is used in folk medicine for the treatment of various illnesses. The present study aimed to identify the chemical constituents and to test the antimicrobial and anticancer activities of an ethanol extract from B. macrophylla leaves. The extract exhibited excellent antibacterial properties against 9 out of 10 target microorganisms. including four Gram-negative bacteria (Escherichia coli, Shigella flexneri, Vibrio cholera, and Pseudomonas aeruginosa) and four Gram-positive bacteria (Staphylococcus aureus, Listeria monocytogenes, Enterococcus faecalis, and Bacillus cereus), as well as a fungus (Candida albicans). In addition, the extract was also tested on HeLa and human colorectal carcinoma (HCT116) cells to evaluate its cytostatic effects. The ethanol extract was able to inhibit the proliferation of HeLa and HCT116 cells, showing IC50 = 24 ± 0.8 and 28 ± 0.9 µg/mL, respectively, whereas the IC50 values of doxorubicin (standard) were 13.6 ± 1.3 and 15.8 ± 1.1 µg/mL respectively. Also, we identified various bioactive compounds in the extract such as polyphenols, flavonoids, caryophyllene, phytol, and trans-geranylgeraniol by GC-MS, which could contribute to the extract’s biological activities. Therefore, our findings strongly indicate that the constituents of the B. macrophylla ethanol extract could be active against the tested bacteria and fungi as well as cancer cells. Further investigation is needed to understand the mechanisms mediating the antimicrobial and anticancer effects and identify signaling pathways that could be targeted for therapeutic application.

scholarly journals Chemical Constituents fromDaphne giraldiiNitsche and Their Contents Simultaneous Determination by HPLC

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Huyiligeqi ◽  
Xiaoxv Dong ◽  
Chunjing Yang ◽  
Guanling Xu ◽  
Sali Cao ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Reliable Method ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Anticancer Activities ◽  
Isolation And Characterization ◽  
Anti Inflammatory

Daphne giraldiiNitsche (Thymelaeaceae) is widely distributed in the Chinese provinces of Shaanxi, Gansu, and Qinghai, which has been used in Chinese folk medicine to treat ache and rheumatism. Pharmacologic tests have revealed that the plant has anti-inflammatory, analgesic, and anticancer activities. However, there is still not enough systemic investigation on the chemical constituents and the method for the contents simultaneous determination inD. giraldii. Therefore, the isolation and characterization of the compounds from the stem barks of this plant were reported. Moreover, a facile, accurate, and reliable method has been developed and validated for their simultaneous determination using HPLC-DAD.

The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review

2016 ◽  
Vol 44 (01) ◽  
pp. 35-60 ◽  
Author(s):  
Xuenong Zhang ◽  
Wenwen Zhao ◽  
Ying Wang ◽  
Jinjian Lu ◽  
Xiuping Chen
Keyword(s):  
Medicinal Plant ◽  
Skin Diseases ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Psoralea Corylifolia ◽  
Active Components ◽  
Anti Oxidant ◽  
Main Components ◽  
Phytochemical Studies ◽  
Important Medicinal Plant

Psoralea corylifolia Linn. (P. corylifolia) is an important medicinal plant with thousands of years of clinical application. It has been widely used in many traditional Chinese medicine formulas for the treatment of various diseases such as leucoderma and other skin diseases, cardiovascular diseases, nephritis, osteoporosis, and cancer. Phytochemical studies indicated that coumarins, flavonoids, and meroterpenes are the main components of P. corylifolia, and most of these components are present in the seeds or fruits. The extracts and active components of P. corylifolia demonstrated multiple biological activities, including estrogenic, antitumor, anti-oxidant, antimicrobial, antidepressant, anti-inflammatory, osteoblastic, and hepatoprotective activities. This paper systematically summarized literatures on the chemical constituents and biological activities of P. corylifolia, which provided useful information for the further research and development toward this potent medicinal plant.

scholarly journals Twinflower (Linnaea borealis L.) – plant species of potential medicinal properties

2017 ◽  
Vol 63 (3) ◽  
pp. 56-64
Author(s):  
Barbara Thiem ◽  
Elisabeth Buk-Berge
Keyword(s):  
Plant Species ◽  
Skin Diseases ◽  
Chemical Constituents ◽  
Conservation Status ◽  
Folk Medicine ◽  
Short Review ◽  
Medicinal Properties ◽  
Glacial Relict ◽  
Folk Tradition

Summary Twinflower (Linnaea borealis L.) is a widespread circumboreal plant species belonging to Linnaeaceae family (previously Caprifoliaceae). L. borealis commonly grows in taiga and tundra. In some countries in Europe, including Poland, twinflower is protected as a glacial relict. Chemical composition of this species is not well known, however in folk medicine of Scandinavian countries, L. borealis has a long tradition as a cure for skin diseases and rheumatism. It is suggested that twinflower has potential medicinal properties. The new study on lead secondary metabolites responsible for biological activity are necessary. This short review summarizes very sparse knowledge on twinflower: its biology, distribution, conservation status, chemical constituents, and describes the role of this plant in folk tradition of Scandinavian countries.

scholarly journals Phytochemical and GC-MS Analysis of Dendrophthoe falcata (L.f.) Ettingsh Stem

2019 ◽  
pp. 1-8
Author(s):  
N. H. Shahare ◽  
S. K. Bodele
Keyword(s):  
Skin Diseases ◽  
Chemical Constituents ◽  
Trimethylsilyl Ether ◽  
Research Work ◽  
Phytochemical Screening ◽  
Ms Analysis ◽  
The Family ◽  
Phytochemical Constituents ◽  
Important Medicinal Plant ◽  
Dendrophthoe Falcata

Dendrophthoe falcata (L.f.) Ettingsh is an important medicinal plant belonging to the family Loranthaceae. It is perennial, climbing and woody parasitic plant of family Loranthaceae. It is ethnomedicinally used for treating ulcers, asthma, impotence, paralysis skin diseases and wounds. In the present study, an attempt was made to investigate the phytochemical constituents present in the Dendrophthoe falcata (L.f.) Ettingsh stem. The preliminary phytochemical screening in different solvents extract was done by using standard methods. The phytochemical screening revealed the presence of carbohydrates, protein and amino acids, fixed oils and fats, saponins, sterols, alkaloids, phenols, tannins, flavonoids, anthocyanin and anthraquinones in different solvent extracts. GC-MS analysis was performed on the methanolic extract to find out the chemical constituents. The GC-MS study revealed the presence of about 51 bioactive compounds. Cyclopentasiloxane, Cyclohexasiloxane, Cycloheptasiloxane, Cyclooctasiloxane, Cyclononasiloxane, Phthalic acid, Hexadecanoic acid, Cyclodecasiloxane, Cyclononasiloxane, Tetracosane, Tetratriacontane, Benzoic acid, 1-Monolinoleoylglycerol trimethylsilyl ether, Octadecane, ç-Sitosterol are some of the major phytoconstituents reported from the sample. Further research work is needed on these identified compounds to analyse their mode of action and usefulness in phytopharmaceutical industries.

Phytochemistry, Pharmacological Activities, Toxicity and Clinical Application of Momordica cochinchinensis

2019 ◽  
Vol 25 (6) ◽  
pp. 715-728 ◽  
Author(s):  
Hai-Yue Lan ◽  
Bin Zhao ◽  
Yu-Li Shen ◽  
Xiao-Qin Li ◽  
Su-Juan Wang ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Southeast Asia ◽  
Clinical Application ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Pharmacological Activities ◽  
Pharmacological Studies ◽  
Momordica Cochinchinensis

Momordica cochinchinensis (Lour.) Spreng (M. cochinchinensis) is a deciduous vine that grows in Southeast Asia. It is known as gac in Vietnam and as Red Melon in English. Gac is reputed to be extremely benificial for health and has been widely used as food and folk medicine in Southeast Asia. In China, the seed of M. cochinchinensis (Chinese name: Mu biezi) is used as traditional Chinese medicine (TCM) for the treatment of various diseases. More than 60 chemical constituents have been isolated from M. cochinchinensis. Modern pharmacological studies and clinical practice demonstrate that some chemical constituents of M. cochinchinensis possess wide pharmacological activities, such as anti-tumor, anti-oxidation, anti-inflammatory, etc. This paper reviews the phytochemistry, pharmacological activities, toxicity, and clinical application of M. cochinchinensis, aiming to bring new insights into further research and application of this ancient herb.

Isolation and HPLC Determination of the Chemical Components of Gentianella acuta (Michx.) Hulten

2018 ◽  
Vol 15 (1) ◽  
pp. 21-33
Author(s):  
Ying Wei ◽  
Yongqiao Liu ◽  
Yifan Hele ◽  
Weiwei Sun ◽  
Yang Wang ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
High Speed ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Gradient Elution ◽  
Chemical Components ◽  
Isolation And Characterization ◽  
Major Chemical ◽  
Main Components ◽  
First Time

Background: Gentianella acuta (Michx.) Hulten is an important type of medicinal plant found in several Chinese provinces. It has been widely used in folk medicine to treat various illnesses. However, there is not enough detailed information about the chemical constituents of this plant or methods for their content determination. Objective: The focus of this work is the isolation and characterization of the major chemical constituents of Gentianella acuta, and developing an analytical method for their determination. Methods: The components of Gentianella acuta were isolated using (1) ethanol extraction and adsorption on macroporous resin. (2) and ethyl acetate extraction and high speed countercurrent chromatography. A HPLC-DAD method was developed using a C18 column and water-acetonitrile as the mobile phase. Based on compound polarities, both isocratic and gradient elution methods were developed. Results: A total of 29 compounds were isolated from this plant, of which 17 compounds were isolated from this genus for the first time. The main components in this plant were found to be xanthones. The HPLC-DAD method was developed and validated for their determination, and found to show good sensitivity and reliability. Conclusion: The results of this work add to the limited body of work available on this important medicinal plant. The findings will be useful for further investigation and development of Gentianella acuta for its valuable medicinal properties.

scholarly journals Perceptions of Ghanaian traditional health practitioners, primary health care workers, service users and caregivers regarding collaboration for mental health care

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Solomon Nyame ◽  
Edward Adiibokah ◽  
Yasmin Mohammed ◽  
Victor C. Doku ◽  
Caleb Othieno ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Care ◽  
Human Rights ◽  
Primary Health Care ◽  
Service Users ◽  
Traditional Health ◽  
Healthcare Needs ◽  
Primary Health ◽  
Traditional Health Practitioners ◽  
Health Practitioners

Abstract Background In low- and middle-income countries, the paucity of conventional health services means that many people with mental health problems rely on traditional health practitioners (THPs). This paper examines the possibility of forging partnerships at the Primary Health Care (PHC) level in two geopolitical regions of Ghana, to maximize the benefits to both health systems. Methods The study was a qualitative cross-sectional survey. Eight (8) focus group discussions (FGDs) were conducted between February and April 2014. The views of THPs, PHC providers, service users (i.e. patients) and their caregivers, on the perceived benefits, barriers and facilitators of forging partnerships were examined. A thematic framework approach was employed for analysis. Results The study revealed that underlying the widespread approval of forging partnerships, there were mutual undertones of suspicion. While PHC providers were mainly concerned that THPs may incur harms to service users (e.g., through delays in care pathways and human rights abuses), service users and their caregivers highlighted the failure of conventional medical care to meet their healthcare needs. There are practical challenges to these collaborations, including the lack of options to adequately deal with human rights issues such as some patients being chained and exposed to the vagaries of the weather at THPs. There is also the issue of the frequent shortage of psychotropic medication at PHCs. Conclusion Addressing these barriers could enhance partnerships. There is also a need to educate all providers, which should include sessions clarifying the potential value of such partnerships.

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