scholarly journals Kaposi Sarcoma among HIV Infected Patients in Lagos University Teaching Hospital, Nigeria: A 14-Year Retrospective Clinicopathological Study

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Olakanmi Akinde ◽  
Omobolade Obadofin ◽  
Titilope Adeyemo ◽  
Oladipo Omoseebi ◽  
Nzechukwu Ikeri ◽  
...  

Background.Despite the increased incidence of Kaposi sarcoma (KS) resulting from the Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) pandemic, there is still significant underreporting of KS in this environment.Objectives.This study was aimed at determining the incidence and clinicopathologic patterns of KS among HIV infected patients in Lagos University Teaching Hospital (LUTH), Nigeria, over a 14-year period: January 2000 to December 2013.Methodology.The materials for this study included patients’ hospital clinical files, duplicate copies of histopathologic reports, and tissue blocks and corresponding archival slides in the Anatomic and Molecular Pathology Department and the HIV/AIDS unit of the Department of Haematology.Results.Within the study period, 182 cases of KS were diagnosed, accounting for 1.2% of all patients managed for HIV/AIDS and 2.99% of solid malignant tumours. The male-to-female ratio and modal age group were 1 : 1.3 and 5th decade, respectively. Most cases (90%) had purely mucocutaneous involvement with the lower limb being the commonest site (65.8%). The majority of lesions were plaques (65.8%). Vascular formation was the predominant histologic type seen (43.5%).Conclusion.KS in Lagos followed the same epidemiologic trend as other centers in Nigeria, with an increasing incidence in this era of HIV/AIDS.

2017 ◽  
Vol 5 (2) ◽  
pp. 1-12
Author(s):  
Nur Syamsi NL

AIDS (Acquired Immunodeficiency Syndrome) adalah syndrom yang timbul akibat adanya virus HIV (Human Immunodeficiency Virus) yang menyerang sistem kekebalan tubuh manusia. HIV/AIDS dapat menular melalui darah, sperma, cairan vagina, dan ASI (Air Susu Ibu). Penelitian ini dilakukan di Akademi Kebidanan Sandi Karsa Makassar yang terletak di jalan Bung lorong 2, Kelurahan Tamalanrea, Kecamatan Tamalanrea Jaya, Makassar. Jenis penelitian yang digunakan dalam penelitian ini bersifat deskriptif. Besarnya sampel yang digunakan adalah 30 responden dari 600 populasi yang dipilih secara Total Sampling. Di mana dalam pengambilan data digunakan instrumen berupa kuesioner yang dibagikan kepada responden. Dari keseluruhan responden didapatkan tingkat pengetahuan mahasiswa Akademi Kebidanan Sandi Karsa Makassar yang diteliti didapat 15 mahasiswa (50%) yang tingkat pengetahuan baik tentang HIV/AIDS dan terdapat 14 mahasiswa (46,7%) yang tingkat pengetahuan cukup tentang HIV/AID dan terdapat 1 mahasiswa (3,3%) yang tingkat pengetahuan kurang tentang HIV/AIDS


2010 ◽  
Vol 50 (3) ◽  
pp. 154-155
Author(s):  
B L Meel

Traditional healers contribute significantly to the level of health-care systems in Africa. They could play an important role in the prevention and care of patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in the community. The traditional healing system deals with psychosocial stress associated with HIV/AIDS as well as herbal medications. Sometimes, herbal medicine causes serious life-threatening complications. Two case reports are presented in this article. The first is a 48-year-old woman with HIV who was made to drink a large volume of a herbal decoction to stimulate vomiting in the belief that cleansing the bowel would rid the system of the disease. The second is a 25-year-old young man who had a herbal enema, which resulted in gangrene of the large bowel. The case histories, mechanism of action and causes of death are discussed.


2021 ◽  
Vol 2 (1) ◽  
pp. 55-63
Author(s):  
Machria Rachman

HIV (Human Immunodeficiency Virus)  dan AIDS (Acquired Immunodeficiency Syndrome masih menjadi ancaman kesehatan masyarakat secara global. Prevalensi HIV/AIDS di Kabupaten Banyuwangi juga cukup tinggi yakni 4.557 kasus. Cara penularan HIV terbesar adalah melalui hubungan seksual (71 %). Sejumlah 18,23% orang dengan HIV/AIDS (ODHA) adalah wanita pekerja seks (WPS). Meskipun lokalisasi di Banyuwangi telah resmi ditutup pada tahun 2013, namun praktik prostitusi masih terselubung dijalankan. Hubungan seksual tanpa kondom menjadi mata rantai penyebaran HIV/AIDS di masyarakat. Tujuan penelitian ini adalah untuk mengetahui korelasi pengetahuan dan sikap WPS dengan persuasi penggunaan kondom di eks lokalisasi Gempol Porong Kabupaten Banyuwangi. Desain penelitian adalah analitik kuantitatif dengan menggunakan pendekatan cross sectional. Sampel penelitian yaitu WPS di Eks Lokalisasi Gempol Porong berjumlah 32 orang yang diambil dengan teknik Total sampling. Pengambilan data dengan metode angket dan dianalisis statistik menggunakan SPSS 20.0 version. Hasil penelitian menunjukkan bahwa WPS yang memiliki pengetahuan rendah dalam penanggulangan HIV/AIDS sebanyak 56,2 %, sikap negatif sebesar 53,1% dan sebanyak 59,4% tidak melakukan persuasi penggunaan kondom. Analisis uji chi-Square menunjukkan ada hubungan antara pengetahuan WPS dalam penanggulangan HIV/AIDS dengan persuasi penggunaan kondom (ρ = 0,002α), serta ada hubungan antara sikap WPS dalam upaya penanggulangan HIV/AIDS dengan persuasi penggunaan kondom (nilai ρ = 0,000α). Variabel yang berpengaruh terhadap penanggulangan HIV/AIDS dengan persuasi penggunaan kondom adalah sikap, dengan  probabilitas sikap negatif WPS sebesar 78%. Penelitian ini diharapkan dapat memberikan masukan pihak terkait guna peningkatan 100% penggunaan kondom sehingga dapat menekan angka pertumbuhan HIV/AIDS di Kabupaten Banyuwangi.


2011 ◽  
Vol 2011 ◽  
pp. 1-17 ◽  
Author(s):  
Anil Kumar ◽  
Bhargavi Mazinder Boruah ◽  
Xing-Jie Liang

Gold nanoparticles (AuNPs) are currently playing a significant role for human welfare in the field of clinical diagnosis as well as several biomedical applications. More and more research shows thatAuNPs-based technologies are becoming promising approaches in cancer research and AIDS treatment. In this paper, we have focused mainly on the exploitation of unique and characteristic properties ofAuNPs such as surface plasmon resonance (SPR), surface enhance Raman scattering (SERS), magnetic properties (MRI), and fluorescence behavior shown upon conjugation with biological and biocompatible ligands. These properties find wide prevalence in biodiagnostics like plasmon-based labeling and imaging, enzyme-linked immunosorbant assay (ELISA), and electrochemical-based methods that can pave the way for developing novel techniques towards diagnosis and therapy of cancer and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS).


2018 ◽  
Vol 32 (5) ◽  
pp. 534-545 ◽  
Author(s):  
Erik W. Skoglund ◽  
Kierra M. Dotson ◽  
Casey J. Dempsey ◽  
Christy P. Su ◽  
Farnaz Foolad ◽  
...  

Purpose: The most significant peer-reviewed articles pertaining to infectious diseases (ID) pharmacotherapy, as selected by panels of ID pharmacists, are summarized. Summary: Members of the Houston Infectious Diseases Network (HIDN) were asked to nominate peer-reviewed articles that they believed most contributed to the practice of ID pharmacotherapy in 2017, including the areas of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). A list of 33 articles related to general ID pharmacotherapy and 4 articles related to HIV/AIDS was compiled. A survey was distributed to members of the Society of Infectious Diseases Pharmacists (SIDP) for the purpose of selecting 10 articles believed to have made the most significant impact on general ID pharmacotherapy and the single significant publication related to HIV/AIDS. Of 524 SIDP members who responded, 221 (42%) and 95 (18%) members voted for general pharmacotherapy- and HIV/AIDS-related articles, respectively. The highest ranked articles are summarized below. Conclusion: Remaining informed on the most significant ID-related publications is a challenge when considering the large number of ID-related articles published annually. This review of significant publications in 2017 may aid in that effort.


Author(s):  
Sandra Augusta Pedro Alberto ◽  
Janete Lane Amadei

Angola, país Africano, registra perdas consideráveis relacionadas às doenças transmissíveis e às mortes prematuras e evitáveis, principalmente, de mulheres e de crianças, agravadas pela desestruturação da qual o país foi vítima ao longo do conflito armado. No diagnóstico da AIDS, os exames laboratoriais de contagem de células T CD4+, CD8+ e carga viral são usados como parâmetros para monitorar a saúde dos pacientes, que utilizam a terapia antirretroviral e avaliar o momento certo para iniciar ou modificar esta terapia. Estudo desenvolvido com objetivo de analisar exames para HIV/Aids realizados em Hospital Provincial de Lubango, Angola – África. Estudo descritivo, retrospectivo compreendendo o período de janeiro a junho de 2014. Foram analisados 981 resultados de exames com uma média de 163,5 por mês. A idade média obtida foi de 35 anos, com resultados médios de 385,1/mm3 para CD4+ e 1060,0/ mm3 para CD8+. Os itens que apresentaram significância com p<0,01 foram: procedência ambulatorial; menores valores de CD4+ para os homens, com idade de 60 anos ou mais seguido de 30 a 60 anos. O monitoramento de linfócitos T CD4+ apresentou  valores baixos na maioria da população que realizou os exames, implicando em indicação de terapia antirretroviral e progressão da patologia com comprometimento da saúde das pessoas analisadas. Palavras-chave: Síndrome da Imunodeficiência Adquirida. Gestão de Saúde. Sistema de Saúde. Atendimento Secundário AbstractAngola, an African country, has considerable losses related to communicable diseases and premature and preventable deaths mainly of women and children, aggravated by the destructuring of which the country has been victimized during the armed conflict.The progression of Human Immunodeficiency Virus (HIV) characterized by numerous pathological changes in the cellular immune system. Study designed to analyze tests for HIV / AIDS held in Hospital Provincial  laboratory Lubango, Angola - Africa. Descriptive, retrospective study conducted in Hospital Provincial covering the period from January to June 2014. 981 test results were analyzed spread between the months from January to June 2014 with an average of 163.5 per month. The average age obtained was 35 years, with average scores of 385.1 / mm3 for CD4+ and 1060.0 / mm3 for CD8+. The items which were significant highlights are lower CD4+ values for men aged 60 years or more followed 30-60 years; with outpatient origin. Monitoring of CD4+ T lymphocytes are underestimated in most of the population who performed the tests. This involves antiretroviral therapy indication of the pathology affecting the analyzed people’s health living with HIV / AIDS . Keywords: Acquired Immunodeficiency Syndrome. Health Management. Health System. Secondary Care.


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