scholarly journals Takayasu’s Arteritis in Pregnancy: A Rare Case Report from a Tertiary Care Infirmary in India

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Sheeba Marwah ◽  
Monika Rajput ◽  
Ritin Mohindra ◽  
Harsha S. Gaikwad ◽  
Manjula Sharma ◽  
...  
Keyword(s):  
Late Onset ◽  
Takayasu’S Arteritis ◽  
Interdisciplinary Collaboration ◽  
Tertiary Care ◽  
Pulmonary Arteries ◽  
Reproductive Age ◽  
Chronic Hypertension ◽  
Takayasu's Arteritis ◽  
Rare Case Report ◽  
Reproductive Age Group

Background. Takayasu’s arteritis (TA) is a rare, chronic, inflammatory, progressive, idiopathic arteriopathy, afflicting young women of reproductive age group, causing narrowing, occlusion, and aneurysms of systemic and pulmonary arteries, especially the aorta and its branches. During pregnancy, such patients warrant special attention. An interdisciplinary collaboration of obstetricians, cardiologists, and neurologists is necessary to improve maternal and fetal prognosis. Here a case is reported where a patient with diagnosis of TA, complicated by neurological sequelae, successfully fought the vagaries of the condition twice to deliver uneventfully.Case. 25-year-old G2P1L1 presented at 34 weeks of gestation, with chronic hypertension, with TA, with epilepsy, and with late-onset severe IUGR. Following a multidisciplinary approach, she delivered an alive born low birth weight baby (following induction). Her postpartum course remained uneventful.Conclusion. Pregnancy with TA poses a stringent challenge to an obstetrician. Despite advancements in cardiovascular management and advent of new-fangled drugs, the optimal management for pregnant patients with this disease still remains elusive.

scholarly journals Pregnancy in a rare case of Takayasu’s arteritis: a case report

2019 ◽  
Vol 8 (6) ◽  
pp. 2563
Author(s):  
Kushal Shah ◽  
Vaishali Korde Nayak
Keyword(s):  
Takayasu Arteritis ◽  
Takayasu’S Arteritis ◽  
Tertiary Care ◽  
Fetal Outcome ◽  
Reproductive Age ◽  
Uncontrolled Hypertension ◽  
Care Hospital ◽  
Takayasu's Arteritis ◽  
Asian Origin ◽  
Reproductive Age Group

In Takayasu’s arteritis is a rare, chronic idiopathic vasculitis affecting aorta and its major branches, commonly seen in young women of Asian origin. Incidence is 2.6 cases/million/year. Female of reproductive age group are commonly affected. A 32-year female G3A2 with known case of Takayasu arteritis wanted to continue this pregnancy under tremandous social pressure and came for antenatal care at tertiary care hospital. As the pregnancy advanced, she developed uncontrolled hypertension and severe IUGR. At 30 weeks of gestation, elective LSCS had to be done in view of reduced fetal blood flow and severe growth restriction. She delivered male baby of 1 kg which was shifted to NICU. Patient required cardiac intensive care unit for first 48 hrs and later shifted to ward. Postoperative period was uneventful, and patient could be discharged on 8th day. Baby received intensive NICU care and discharged after 1 month with 2 kg weight. Pregnancy with takayasu arteritis requires a multipronged management from gynaecologist, cardiologist, cardiac anaesthetist and neonatologist for favourable maternal and fetal outcome.

scholarly journals Large cervical fibroid: a rare case report

2019 ◽  
Vol 8 (8) ◽  
pp. 3414
Author(s):  
Sunanda N.
Keyword(s):  
Uterine Fibroids ◽  
Total Abdominal Hysterectomy ◽  
Large Mass ◽  
Abdominal Hysterectomy ◽  
Reproductive Age ◽  
Pelvic Tumors ◽  
Rare Case Report ◽  
Tender Mass ◽  
Restricted Mobility ◽  
Reproductive Age Group

Although leiomyomas are the most common pelvic tumors presenting in the reproductive age group, cervical fibroids are rare accounting for 2% of all uterine fibroids. We report a case of 40 year old lady presenting with a firm, non-tender mass of 22-24 weeks size pregnant uterus with restricted mobility. Laparotomy showed a large mass arising from the anterior lip of cervix, with a small uterus pushed posteriorly. Enucleation followed by total abdominal hysterectomy was done. Large cervical fibroids are rare, presenting with surgical difficulties. Careful dissection by expert hands is needed in the management of such cases. 

scholarly journals Surgical Correction of Takayasu’s Arteritis Involving Both Coronary and Pulmonary Arteries

2019 ◽  
Vol 107 (6) ◽  
pp. e375-e377
Author(s):  
Hee Jung Kim ◽  
Hyun Jong Lee ◽  
Jae Suk Yoo ◽  
Dong Jin Kim ◽  
Kwang Lee Cho
Keyword(s):  
Takayasu’S Arteritis ◽  
Pulmonary Arteries ◽  
Surgical Correction ◽  
Takayasu's Arteritis

scholarly journals Stenting in Takayasu’s Arteritis: A Case Report

2018 ◽  
Vol 44 (2) ◽  
pp. 109-112
Author(s):  
Mohd Zahid Hussain ◽  
Md. Tariqul Islam ◽  
Tahmina Karim ◽  
Shakhawat Alam ◽  
Mostafizur Rahman Bhuiyan ◽  
...  
Keyword(s):  
Age Of Onset ◽  
Takayasu’S Arteritis ◽  
Late Phase ◽  
Pulmonary Arteries ◽  
Granulomatous Inflammation ◽  
Takayasu's Arteritis ◽  
Pulseless Disease ◽  
Younger Patients ◽  
Asian Populations ◽  
Female Predominance

Takayasu arteritis (TA), also known as idiopathic medial aortopathy or pulseless disease, is a granulomatous large vessel vasculitis that predominantly affects the aorta and its major branches. It may also affect the pulmonary arteries. The exact cause is not well known but the pathology is thought to be similar to giant cell arteritis. There is segmental and patch granulomatous inflammation of the aorta which results in stenosis, thrombosis and aneurysm formation. Half of the patients present with an initial systemic illness whereas the other 50% present with late-phase complications. There is a strong female predominance (F: M ~ 9:1), an increased prevalence in Asian populations, and it tends to affect younger patients (<50 years of age). The typical age of onset is at around 15-30 years of age. Here, it is reported a case of 9 years old girl with Takayasu’s arteritis.

Pulmonary Arteries Involvement in Takayasu's Arteritis: Two Cases and Literature Review

2011 ◽  
Vol 41 (3) ◽  
pp. 461-470 ◽  
Author(s):  
Kohava Toledano ◽  
Ludmila Guralnik ◽  
Avraham Lorber ◽  
Amos Ofer ◽  
Mordechai Yigla ◽  
...  
Keyword(s):  
Literature Review ◽  
Takayasu’S Arteritis ◽  
Pulmonary Arteries ◽  
Takayasu's Arteritis

scholarly journals Takayasu's arteritis in a patient with suspected acute coronary syndrome — a literature review and a case report

2021 ◽  
Vol 26 ◽  
pp. 4345
Author(s):  
D. A. Grabovyi ◽  
J. V. Dzhinibalaeva ◽  
E. V. Adonina ◽  
D. V. Duplyakov
Keyword(s):  
Acute Coronary Syndrome ◽  
Case Report ◽  
Literature Review ◽  
Takayasu’S Arteritis ◽  
Pulmonary Arteries ◽  
Diagnostic Techniques ◽  
Takayasu's Arteritis ◽  
Coronary Syndrome ◽  
American College Of Rheumatology ◽  
Wide Range

Takayasu's arteritis is a chronic granulomatous vasculitis of large vessels of unclear etiology, predominantly affecting the aorta and its main branches, with possible involvement of the coronary and pulmonary arteries. The true prevalence of this disease is unknown, but it is extremely low, given the rare diagnosis and the absence of pathognomonic symptoms. In clinical practice, the criteria proposed by the American College of Rheumatology are used for making a diagnosis. A wide range of imaging diagnostic techniques plays a significant role. This article provides a literature review and a case report of Takayasu's arteritis in a patient admitted with an acute coronary syndrome.

scholarly journals Challenges with Takayasu arteritis in pregnancy: a case report

2021 ◽  
Vol 10 (5) ◽  
pp. 2115
Author(s):  
Monika Dalal ◽  
Vani Malhotra ◽  
Smiti Nanda ◽  
Meenakshi Chauhan ◽  
Vandana Rani ◽  
...  
Keyword(s):  
Takayasu Arteritis ◽  
Interdisciplinary Collaboration ◽  
Pulmonary Arteries ◽  
Good Control ◽  
Cardiovascular Complications ◽  
Unknown Etiology ◽  
Chronic Hypertension ◽  
Increased Risk ◽  
Life Threatening ◽  
Female Baby

Takayasu’s arteritis (TA) is a rare, chronic, inflammatory, large vessel vasculitis (LVV) of unknown etiology characterized by narrowing, occlusion, and aneurysms of systemic and pulmonary arteries affecting especially the aorta and its branches. Pregnant patients are at increased risk of cardiovascular complications, including hypertension and congestive heart failure, which may jeopardize both maternal and fetal outcomes, so one should pay special attention to these patients. We present a case of 30-year-old female G5P3L2A1 with 9 months of amenorrhea with previous 2 LSCS with chronic hypertension and superimposed pre-eclampsia with oligohydraminos. She was a known case of Takayasu arteritis, diagnosed since she was 16 years old. Her lower limb pulses were palpable with absent upper limb pulses. On Echocardiography there was dilated aortic root, moderate MR and LVEF was 55%. She proceeded to have emergency LSCS under spinal anesthesia in view of severe pre-eclampsia with previous 2 LSCS at 35 week and delivered alive healthy female baby weight 2.1 kg. A life-threatening maternal cardiovascular complication is observed in more than 5% of pregnant women with TA. Hypertension is present in 90% cases of Takayasu arteritis. A good control of TA disease activity and arterial hypertension before conception and during pregnancy is important to improve feto-maternal outcomes. Pregnancies in the setting of TA should be considered high-risk, requiring a close interdisciplinary collaboration of rheumatologists, nephrologists and obstetrician’s specialists involved in care of TA.

scholarly journals Quality of Life and Stigma among Women with Epilepsy during Their Reproductive Years

2021 ◽  
Vol 11 (1) ◽  
pp. 63-71
Author(s):  
Pallerla Srikanth ◽  
Mysore Narasimha Vranda ◽  
Priya Treesa Thomas ◽  
Kenchaiah Raghvendra
Keyword(s):  
Quality Of Life ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Care Hospital ◽  
Age Group ◽  
Stigma Scale ◽  
The Impact ◽  
The Relationship ◽  
Reproductive Age Group

Background and Purpose: The purpose of this study was to understand the relationship between quality of life and stigma among reproductive age group women with epilepsy.Methods: A cross-sectional descriptive study was conducted to assess the data from the 49 women with epilepsy from a tertiary care hospital in India. Quality of life was evaluated with the quality of life in epilepsy-31 questionnaire and stigma was evaluated with the stigma scale of epilepsy. Data also included socio-demographic and clinical characteristics.Results: The mean age of the participants was 24.67±3.72 years. Quality of life total score (r=-0.485**) and seizure worry domain (r=-0.427**) were significantly negatively correlated with stigma total score at p<0.01 level. Being uneducated, married, unemployed, having children, having generalized tonic-clonic seizures, duration of illness (˃10 years), and consuming levetiracetam, anti-epileptic drug (AED), were the significant contributing factors for low quality of life among women with epilepsy during the reproductive age group. Belonging to lower socio-economic status and taking more than two AEDs were also associated with lower quality of life among women with epilepsy, which are trending towards significance.Conclusions: The study assessed the relationship between the quality of life and the Stigma scale of epilepsy and demonstrated the impact of stigma and quality of life on socio-demographic and clinical variables of women with epilepsy under the reproductive age group. To enhance the quality of life and reduce the stigma levels among women with epilepsy, some of the modifiable parameters can be considered by the multidisciplinary health care professionals from the findings of the current research.

scholarly journals Role of Mifepristone in treatment of uterine fibroid: an experience from tertiary care centre in South India

2019 ◽  
Vol 8 (3) ◽  
pp. 974
Author(s):  
S. V. Nachiketha ◽  
Veena Hadi
Keyword(s):  
Side Effects ◽  
Uterine Fibroid ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Tertiary Care Centre ◽  
Common Benign Tumour ◽  
Fibroid Volume ◽  
Reproductive Age Group

Background: Uterine fibroid are the most common benign tumour of the uterus and is seen in 20% of women in their reproductive age group. The aim of the study was to evaluate effect of Mifepristone on uterine fibroid with reference to reduction in size of fibroid and change in symptomatic profile.Methods: It is a hospital based interventional study conducted at KIMS Hubli hospital. 98 patients with symptomatic fibroid uterus were given 50mg of Mifepristone on alternate day for 3 months.Results: Mifepristone treatment significantly reduced mean PBAC score from baseline score of 212.61 to 20.39 at the end of 3rd month of therapy. Mean fibroid volume also reduced significantly from baseline value of 237.95cm3 to 30.45cm3 after 3 months of treatment. At the end of therapy hemoglobin was raised from 9.57g/dl at baseline to 10.42g/dl after 3 months of treatment. No major side effects were observed, and 7% patients had hysterectomy.Conclusions: Mifepristone is very useful option in perimenopausal women with symptomatic fibroid. It reduces fibroid size and its symptoms without any major side effects. However, future long term RCTs are needed to assess the safety and efficacy of Mifepristone.

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