scholarly journals Brain-Derived Neurotropic Factor Val66Met Polymorphism and Posttraumatic Stress Disorder among Survivors of the 1998 Dongting Lake Flood in China

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Wenjie Dai ◽  
Atipatsa C. Kaminga ◽  
Xin Wu ◽  
Shi Wu Wen ◽  
Hongzhuan Tan ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Dongting Lake ◽  
Multivariable Logistic Regression Analysis ◽  
Ptsd Symptoms ◽  
Face To Face ◽  
Neurotropic Factor ◽  
Bdnf Rs6265

Objective. This study mainly aimed to explore the association between brain-derived neurotropic factor (BDNF) Val66Met polymorphism and posttraumatic stress disorder (PTSD) among flood survivors in China. Methods. Individuals who experienced the 1998 Dongting Lake flood in Southeast Huarong, China, were enrolled in this study. Qualified health personnel carried out face-to-face interviews with participants. PTSD was identified using PTSD Checklist-Civilian version (PCL-C). Blood samples were collected from the participants to extract DNA for genotyping. Results. A total of 175 participants were enrolled in this study. The prevalence of PTSD among flood survivors at 17-year follow-up was 16.0% (28/175). Individuals with PTSD were more likely to be female, experience at least three flood-related stressors, experience at least three postflood stressors, and carry the Met than those without PTSD. Compared with Val/Val homozygotes, Met carriers had higher scores of PCL-C (mean ± standard error: 23.60±7.23 versus 27.19±9.48, P<0.05). Multivariable logistic regression analysis indicated that Met carriers (aOR = 4.76, 95% CI = 1.02–22.15, P<0.05) were more likely to develop PTSD than Val/Val homozygotes. Conclusions. Met carriers for BDNF rs6265 are at higher risk of developing PTSD and also exhibit more severe PTSD symptoms than Val/Val homozygotes among flood survivors in China.

scholarly journals Results of the first randomized controlled trial of integrated cognitive-behavioral therapy for eating disorders and posttraumatic stress disorder

2021 ◽  
pp. 1-10
Author(s):  
Kathryn Trottier ◽  
Candice M. Monson ◽  
Stephen A. Wonderlich ◽  
Ross D. Crosby
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Eating Disorders ◽  
Randomized Controlled Trial ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Behavioral Therapy ◽  
Controlled Trial ◽  
Ptsd Symptoms ◽  
Randomized Controlled

Abstract Background Eating disorders (EDs) and posttraumatic stress disorder (PTSD) frequently co-occur and can share a functional relationship. The primary aim of this initial randomized controlled trial was to determine whether integrated cognitive-behavioral therapy (CBT) for co-occurring ED-PTSD was superior to standard CBT for ED in improving PTSD symptoms. Intervention safety and desirability, as well as the relative efficacy of the treatments in improving anxiety, depression, and ED symptomatology, were also examined. Methods Following a course of intensive ED treatment, individuals with ED-PTSD were recruited to participate and randomized to integrated CBT for ED-PTSD or standard CBT for ED. The sample consisted of 42 individuals with a range of ED diagnoses. Outcomes were assessed at end-of-treatment, 3-, and 6-month follow-up using interview and self-report measures. Results Mixed models revealed significant interactions of time and therapy condition on clinician-rated and self-reported PTSD symptom severity favoring Integrated CBT for ED-PTSD. Both treatments were associated with statistically significant improvements in PTSD, anxiety, and depression. Improvements were maintained at 3- and 6-month follow-up. There was good safety with both interventions, and satisfaction with both treatments was high. However, there was a stronger preference for integrated treatment. Conclusions Integrating CBTs for PTSD and ED following intensive ED treatment is safe, desirable, and efficacious for improving PTSD symptoms. Future studies with larger sample sizes are needed to determine whether Integrated CBT for ED-PTSD provides benefits over standard CBT for ED with respect to ED outcomes.

Does Writing Reduce Posttraumatic Stress Disorder Symptoms?

2003 ◽  
Vol 18 (5) ◽  
pp. 569-580 ◽  
Author(s):  
Pamela B. Deters ◽  
Lillian M. Range
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Suicidal Ideation ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Traumatic Experiences ◽  
Ptsd Symptoms ◽  
Initial State ◽  
Posttraumatic Stress Disorder Symptoms ◽  
Better Than

To see if writing about their trauma lessened PTSD and related symptoms, 57 undergraduates, previously screened for traumatic experiences, wrote for 15 minutes on 4 days across 2 weeks about either their trauma or a trivial topic. They reported PTSD, impact, suicide ideas, dissociation, and depression pre-, post-, and at 6-week follow-up testing. Trauma and trivial writers were not different. Surprisingly, at follow-up everyone reported less severe PTSD symptoms, impact, and dissociation, and fewer health visits, but about the same suicidal ideation and depression. On PTSD symptoms and impact, the pattern of improvement was different: Those writing about trauma got worse at posttesting, but improved to better than their initial state by follow-up. Those writing about a trivial topic got better by posttesting, and held that position at follow-up. In this project, writing seemed to reduce PTSD symptoms regardless of whether it concerned the trauma or what they ate for lunch.

E-CONSALTING BY TELEPSYCHIATRIC SERVICES AND WAR RELATED POSTTRAUMATIC STRESS DISORDER

Psymedica ◽  
2010 ◽  
Vol 1 (1-2) ◽  
Author(s):  
Milan Stojaković ◽  
Bogdan Stojaković
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Rating Scale ◽  
Stress Disorder ◽  
Psychiatric Patients ◽  
Ptsd Symptoms ◽  
Posttraumatic Stress Syndrome ◽  
Stress Syndrome ◽  
Wide Range

BACKGROUND AND AIMS: This study was examination e-consalting by Telepsychiatry of war related posttraumatic stress disorder(PTSD),METHODS; Patients with PTSD have different symptoms.The authors' objective is to analize component of symptoms in PTSD.The subjects were 180 male psychiatric patients by Telepsychiatry and e-consulting with war relatedPTSD by videoconferencing via broadband ADSL by 2 Mbps. Posttraumatic stress syndrome-PTSSscale and 20-item.Zung self-rating scale was used to assess state measures of symptom severity,RESULTS: The symptoms of prolonged PTSS (posttraumatic stress syndrome) with duration betweensix moths and two years had been founded at 138 (76,7 %) and 42 (23,3 %) of patients had no PTSS:symptoms of depression had been found at 148 (82,2 %) patients. The enduring personality exchangeafter catastrophic expiriense (P62.0), had been found at 25 (13,8 %) patients (P< 0,01); symptoms ofdepression had been found at 61 (33.8 %) patients after two years,CONCLUSIONS: Evolution of PTSD symptoms and continued examination and follow-up by Telepsychiatry service and e-consalting may be important in predicting the eventual development ofdepressive symptoms and precipitation of F 62.0 enduring personality exchange after catastrophicexperience in the war related PTSD. Consequently.Telepsychiatry service and e-consalting it is able toserve not only PTSD but also wide range of other patient.

Intervening on Persistent Posttraumatic Stress Disorder: Rumination-Focused Cognitive and Behavioral Therapy in a Population of Young Survivors of the 1994 Genocide in Rwanda

2009 ◽  
Vol 23 (2) ◽  
pp. 107-113 ◽  
Author(s):  
Vincent Sezibera ◽  
Nady Van Broeck ◽  
Pierre Philippot
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Behavioral Intervention ◽  
Rating Scale ◽  
Stress Disorder ◽  
Behavioral Therapy ◽  
Ptsd Symptoms ◽  
Young Survivors ◽  
Cognitive And Behavioral Therapy

This study assessed the outcome of a brief rumination-focused cognitive and behavioral intervention in treating posttraumatic stress disorder (PTSD) symptoms among Rwandan adolescent survivors of the 1994 genocide. All participants (54.5% female, N = 22) aged between 15 and 18 years (M = 16.55, SD = 0.96) met criteria for PTSD as assessed by the PTSD self-rating scale (UCLA PTSD index). Measures included questionnaires assessing PTSD, depression, and somatization. Data were obtained at four points: (1) 11 years after the genocide (baseline), (2) 13 years after the genocide (pretreatment), (3) posttreatment (2 weeks after the treatment), and (4) follow-up (2 months after the treatment). PTSD symptoms increased between baseline and pretreatment. The intervention was associated with a reduction in PTSD symptoms, with gains maintained at follow-up.

scholarly journals Mental health care in post-genocide Rwanda: evaluation of a program specializing in posttraumatic stress disorder and substance abuse

2016 ◽  
Vol 3 ◽  
Author(s):  
L. C. Ng ◽  
B. Harerimana
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Program Evaluation ◽  
Posttraumatic Stress ◽  
Psychotic Disorders ◽  
Stress Disorder ◽  
Information Management System ◽  
Descriptive Statistics ◽  
Ptsd Symptoms ◽  
Resource Information

Background.Following the genocide, millions of Rwandans are likely living with posttraumatic stress disorder (PTSD). Le Centre Psychothérapeutique Icyizere provides the only specialized treatment for PTSD in the Rwandan healthcare system.Methods.Demographics, diagnosis, treatment, outcomes, and scores on assessments of functioning and PTSD were recorded from clinical charts of all patients receiving care between October 2013 and 2014. Descriptive statistics and within-group t tests comparing functional impairment and PTSD symptoms at intake to discharge and follow-up were calculated.Results.A total of 719 patients (55.08% male) received care. Patients were more educated, more likely to live in the capital, and less likely to be married than the general population. Patients reported high desire for, and strong satisfaction with, care. Most patients (55.60%) were still in care by the end of the program evaluation. Functioning improved from intake to discharge (p < 0.001), and improvements were sustained at follow-up (p < 0.001). Most adults were diagnosed with psychotic disorders, substance use disorders, or depression. Only 20 patients were diagnosed with PTSD, and symptoms were improved at discharge (p = 0.003).Conclusions.This program evaluation demonstrated the utility of a low-resource information management system to provide clarity about the patient population and outcomes. Results suggest that services are effective and sustainable, although people with PTSD were not the primary recipients of care. Disparities in care by diagnosis, education, marital status, and geography are discussed. Results have contributed to changes in service delivery and care and efforts to increase access to care.

Posttraumatic Anger, Recalled Peritraumatic Emotions, and PTSD in Victims of Violent Crime

2011 ◽  
Vol 26 (17) ◽  
pp. 3561-3579 ◽  
Author(s):  
M. J. J. Kunst ◽  
F. W. Winkel ◽  
S. Bogaerts
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Ptsd Symptom ◽  
Longitudinal Design ◽  
Future Research ◽  
Ptsd Symptoms ◽  
Cross Sectional ◽  
Threat Perceptions

A mixed cross-sectional and longitudinal design was employed to explore the association between posttraumatic anger and posttraumatic stress disorder (PTSD; symptoms) in victims of civilian violence. It was speculated that this relationship is mainly due to concurrent recalled peritraumatic emotions. Such emotions may be interpreted to result from anger-rooted threat perceptions and to share similarities with posttraumatic intrusion symptoms. In addition, predictors of PTSD maintenance were investigated. Cross-sectional data indicated that posttraumatic anger and several indices of PTSD were highly interconnected. Recalled peritraumatic emotions partly accounted for the relation between posttraumatic anger and posttraumatic intrusions ( n = 177). Only posttraumatic intrusions were associated with PTSD symptom persistence at follow-up ( n = 56). Findings were discussed in light of study limitations and directions for future research.

scholarly journals Posttraumatic stress disorder and changes in diet quality over 20 years among US women

2019 ◽  
pp. 1-10
Author(s):  
Yongjoo Kim ◽  
Andrea L. Roberts ◽  
Eric B. Rimm ◽  
Lori B. Chibnik ◽  
Shelley S. Tworoger ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Diet Quality ◽  
Stress Disorder ◽  
Healthy Eating Index ◽  
Ptsd Symptoms ◽  
Increased Risk ◽  
Over Time ◽  
New Onset

Abstract Background Individuals with posttraumatic stress disorder (PTSD) are at increased risk of various chronic diseases. One hypothesized pathway is via changes in diet quality. This study evaluated whether PTSD was associated with deterioration in diet quality over time. Methods Data were from 51 965 women in the Nurses' Health Study II PTSD sub-study followed over 20 years. Diet, assessed at 4-year intervals, was characterized via the Alternative Healthy Eating Index-2010 (AHEI). Based on information from the Brief Trauma Questionnaire and Short Screening Scale for DSM-IV PTSD, trauma/PTSD status was classified as no trauma exposure, prevalent exposure (trauma/PTSD onset before study entry), or new-onset (trauma/PTSD onset during follow-up). We further categorized women with prevalent exposure as having trauma with no PTSD symptoms, trauma with low PTSD symptoms, and trauma with high PTSD symptoms, and created similar categories for women with new-onset exposure, resulting in seven comparison groups. Multivariable linear mixed-effects spline models tested differences in diet quality changes by trauma/PTSD status over follow-up. Results Overall, diet quality improved over time regardless of PTSD status. In age-adjusted models, compared to those with no trauma, women with prevalent high PTSD and women with new-onset high PTSD symptoms had 3.3% and 3.6% lower improvement in diet quality, respectively, during follow-up. Associations remained consistent after adjusting for health conditions, sociodemographics, and behavioral characteristics. Conclusions PTSD is associated with less healthy changes in overall diet quality over time. Poor diet quality may be one pathway linking PTSD with a higher risk of chronic disease development.

EMDR Treatment of Past Domestic Violence: A Clinical Vignette

2009 ◽  
Vol 3 (3) ◽  
pp. 192-197 ◽  
Author(s):  
Kristin M. Phillips ◽  
Blanche Freund ◽  
Joanne Fordiani ◽  
Rachel Kuhn ◽  
Gail Ironson
Keyword(s):  
Domestic Violence ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Outcome Measures ◽  
Stress Disorder ◽  
Ptsd Symptoms ◽  
Symptoms Of Depression ◽  
The Third

This case study describes the use of eye movement desensitization and reprocessing (EMDR) for a woman who met criteria for posttraumatic stress disorder (PTSD) related to past domestic violence. Outcome measures were used to assess the client’s symptoms at intake, after the third and sixth active EMDR sessions, and at 1- and 3-month follow-ups. In addition to the use of outcome measures, at 3-month follow-up the client was evaluated by a therapist who was blind to the type of treatment the client had received. Results indicated that after nine active sessions of EMDR, the client no longer met criteria for PTSD and no longer endorsed symptoms of depression or intrusive thoughts. Thus, EMDR was successful in treating PTSD symptoms associated with past domestic violence, and effects were maintained at 3-month follow-up.

Learning and Consolidation of Verbal Declarative Memory in Patients with Posttraumatic Stress Disorder

2010 ◽  
Vol 218 (2) ◽  
pp. 135-140 ◽  
Author(s):  
Slawomira J. Diener ◽  
Herta Flor ◽  
Michèle Wessa
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Verbal Memory ◽  
Stress Disorder ◽  
Declarative Memory ◽  
Memory Performance ◽  
Verbal Learning ◽  
Depression Scale ◽  
Learning Performance ◽  
Ptsd Symptoms

Impairments in declarative memory have been reported in posttraumatic stress disorder (PTSD). Fragmentation of explicit trauma-related memory has been assumed to impede the formation of a coherent memorization of the traumatic event and the integration into autobiographic memory. Together with a strong non-declarative memory that connects trauma reminders with a fear response the impairment in declarative memory is thought to be involved in the maintenance of PTSD symptoms. Fourteen PTSD patients, 14 traumatized subjects without PTSD, and 13 non-traumatized healthy controls (HC) were tested with the California Verbal Learning Test (CVLT) to assess verbal declarative memory. PTSD symptoms were assessed with the Clinician Administered PTSD Scale and depression with the Center of Epidemiological Studies Depression Scale. Several indices of the CVLT pointed to an impairment in declarative memory performance in PTSD, but not in traumatized persons without PTSD or HC. No group differences were observed if recall of memory after a time delay was set in relation to initial learning performance. In the PTSD group verbal memory performance correlated significantly with hyperarousal symptoms, after concentration difficulties were accounted for. The present study confirmed previous reports of declarative verbal memory deficits in PTSD. Extending previous results, we propose that learning rather than memory consolidation is impaired in PTSD patients. Furthermore, arousal symptoms may interfere with successful memory formation in PTSD.

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