scholarly journals FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Ryo Terauchi ◽  
Takashi Wada ◽  
Shumpei Ogawa ◽  
Masanobu Kaji ◽  
Tomohiro Kato ◽  
...  
Keyword(s):  
Detection Rate ◽  
Frequency Doubling ◽  
Fundus Photography ◽  
Control Group ◽  
First Year ◽  
Newly Diagnosed ◽  
Health Checkup ◽  
Frequency Doubling Technology ◽  
Glaucoma Detection ◽  
Comprehensive Health

We aimed to investigate the efficacy of frequency doubling technology (FDT) perimetry for glaucoma detection in comprehensive screening examinations. We performed a retrospective analysis of prospectively collected data of participants who underwent a comprehensive health checkup service. Participants with glaucoma were excluded. In the first year, 2024 participants (46.8 ± 9.4 years) who underwent FDT perimetry and fundus photography were classified as the FDT group, whereas 3052 participants (42.2 ± 8.2 years) who underwent only fundus photography were classified as the non-FDT control group. Participants with abnormal findings on FDT perimetry and/or fundus photography were recommended to undergo further complete examination. All participants reported whether they had been newly diagnosed with glaucoma within 2 years of the first visit. In the FDT group, 23 (1.14%) participants were newly diagnosed with glaucoma. Among them, 20 (87.0%) had abnormal FDT perimetry findings and 12 (52.2%) had abnormal findings on fundus photography. The positive-predictive value (PPV) of FDT perimetry was 16.5% (20/121) and that of fundus photography was 13.3% (12/90). In participants with abnormal findings on both tests, the PPV was 26.2%. In the non-FDT group, 15 (0.49%) participants were newly diagnosed with glaucoma. Among them, 9 (60.0%) had abnormal findings on fundus photography. The PPV of fundus photography was 10.8% (9/83). The glaucoma detection rate, analyzed using age adjustment, was significantly higher in the FDT group than that in the non-FDT group (0.97% versus 0.47%, P=0.041). FDT perimetry, even if performed by nonspecialized physicians, could improve glaucoma detection when used in addition to fundus photography. This study was registered with UMIN000037951.

scholarly journals Prevalence of glaucoma in the Australian National Eye Health Survey

2018 ◽  
Vol 103 (2) ◽  
pp. 191-195 ◽  
Author(s):  
Stuart Keel ◽  
Jing Xie ◽  
Joshua Foreman ◽  
Pei Ying Lee ◽  
Mostafa Alwan ◽  
...  
Keyword(s):  
Low Vision ◽  
Visual Fields ◽  
Frequency Doubling ◽  
Population Based ◽  
Fundus Photography ◽  
Indigenous Australians ◽  
Frequency Doubling Technology ◽  
Eye Health ◽  
Low Vision Rehabilitation ◽  
History Of

AimTo estimate the prevalence of glaucoma in Australia.MethodsThis was a population-based study of 3098 non-Indigenous Australians (50–98 years) and 1738 Indigenous Australians (40–92 years) stratified by remoteness. Each participant underwent a standard examination that included visual field assessment, tonometry and non-mydriatic fundus photography. Two fellowship-trained glaucoma specialists independently assessed relevant case notes (past ocular history, best-corrected visual acuity, frequency doubling technology visual fields, Van Herick grade, intraocular pressure and optic disc-centred photographs) and assigned a diagnosis ranked on a scale of certainty: none, possible, probable or definite glaucoma.ResultsA total of 4792 (99.1%, 3062 non-Indigenous and 1730 Indigenous) participants had retinal photographs in at least one eye that were gradable for glaucoma. The weighted prevalence of glaucoma (definite) in non-Indigenous Australians and Indigenous Australians was 1.5% (95% CI 1.0 to 2.2) and 0.6% (95% CI 0.4 to 1.1), respectively. When definite and probable cases of glaucoma were combined, rates were 3.4% (95% CI 2.7 to 4.3) among non-Indigenous and 1.6% (95% CI 1.1 to 2.3) in Indigenous Australians. Only 52.4% of non-Indigenous Australians and 28.0% of Indigenous Australians with glaucoma self-reported a known history of glaucoma.ConclusionWe estimate that 198 923 non-Indigenous Australians aged 50 years and over and 2139 Indigenous Australians aged 40 years and over have glaucoma. Given the high rates of undiagnosed glaucoma coupled with a significant ageing of the Australian population, improvements in case detection and access to low vision rehabilitation services may be required to cope with the growing burden of glaucoma.

scholarly journals New options for the diagnosis of normal tension glaucoma in the light of Professor V.V. Volkov’s concept of its pathogenesis

2021 ◽  
Vol 14 (2) ◽  
pp. 5-15
Author(s):  
Irina L. Simakova ◽  
Alfina R. Suleimanova ◽  
Natalya P. Baimuratova
Keyword(s):  
Pilot Study ◽  
Optic Nerve ◽  
Frequency Doubling ◽  
Normal Tension Glaucoma ◽  
Lamina Cribrosa ◽  
Control Group ◽  
Healthy Individuals ◽  
Cross Sectional ◽  
Mean Values ◽  
Frequency Doubling Technology

PURPOSE:To measure lamina cribrosa thickness (LCT) and lamina cribrosa depth (LCD), optic nerve subarachnoid space width (ONSASW) in patients with normal tension glaucoma and in healthy individuals and to compare these data with the results of our own pilot study. MATERIALS AND METHODS:The 1st group included 13 patients (22 eyes) with normal tension glaucoma aged 39 to 88 years (59.8 10.9 years). The 2nd (control) group included 10 healthy people (20 eyes) aged 40 to 59 years (47.9 5.5 years). All subjects underwent structural and functional assessment of the optic nerve head using optical coherent tomograph (OCT) RTVue-100 (Optovue, USA), Humphrey perimeter (HFA II 745i, Germany-USA), and our own modification of Frequency Doubling Technology perimetry. LCT and LCD were measured by OCT RS-3000 Advance (Nidek, Japan). To measure ONSASW we used a cross-sectional image of the optic nerve taken with Magnetic Resonance Imaging (GE Optima MR450w MRI, USA). RESULTS:Differences in the 1st and 2nd groups between the mean values of LCT (234.14 27.73 and 336.25 21.0 m, respectively;p= 0.0000), LCD (461.8 101.7 and 361.65 58.2 m, respectively;p= 0.0004) and ONSASW (1.371 0.035 and 1.52 0.133 mm, respectively;p= 0.011) were statistically significant. CONCLUSION:Patients with normal tension glaucoma had significantly higher LCD value with significantly lower LCT and ONSASW values compared to healthy individuals, which is comparable with the results of our pilot study, and confirms the importance of these morphometric criteria in normal tension glaucoma diagnosis verification.

scholarly journals Combining Frequency Doubling Technology Perimetry and Scanning Laser Polarimetry for Glaucoma Detection

2015 ◽  
Vol 24 (8) ◽  
pp. 561-567 ◽  
Author(s):  
Jean-Claude Mwanza ◽  
Joshua L. Warren ◽  
Jessica T. Hochberg ◽  
Donald L. Budenz ◽  
Robert T. Chang ◽  
...  
Keyword(s):  
Frequency Doubling ◽  
Scanning Laser ◽  
Scanning Laser Polarimetry ◽  
Laser Polarimetry ◽  
Frequency Doubling Technology ◽  
Glaucoma Detection

scholarly journals Alterations Induced by Bangerter Filters on the Visual Field: A Frequency Doubling Technology and Standard Automated Perimetry Study

2015 ◽  
Vol 2015 ◽  
pp. 1-8
Author(s):  
Costantino Schiavi ◽  
Filippo Tassi ◽  
Alessandro Finzi ◽  
Mauro Cellini
Keyword(s):  
Visual Field ◽  
Frequency Doubling ◽  
Control Group ◽  
Automated Perimetry ◽  
Standard Automated Perimetry ◽  
Parvocellular Pathway ◽  
Anisometropic Amblyopia ◽  
Frequency Doubling Technology ◽  
Normal Adults

Purpose. To investigate the effects of Bangerter filters on the visual field in healthy and in amblyopic patients.Materials and Methods. Fifteen normal adults and fifteen anisometropic amblyopia patients were analysed with standard automated perimetry (SAP) and frequency doubling technology (FDT) at baseline and with filters 0.8 and 0.1.Results. With 0.1 filter in SAP there was an increase of MD compared with controls (−10.24 ± 1.09 dB) in either the amblyopic (−11.34 ± 2.06 dB;P<0.050) or sound eyes (−11.34 ± 1.66 dB;P<0.030). With filters 0.8 the PSD was increased in the amblyopic eyes (2.09 ± 0.70 dB;P<0.007) and in the sound eyes (1.92 ± 0.29 dB;P<0.004) compared with controls. The FDT-PSD values in the control group were increased with the interposition of the filters compared to baseline (0.8;P<0.0004and 0.1;P<0.0010). We did not find significant differences of the baseline PSD between amblyopic eyes (3.80 ± 2.21 dB) and the sound eyes (4.33 ± 1.31 dB) and when comparing the filters 0.8 (4.55 ± 1.50 versus 4.53 ± 1.76 dB) and 0.1 (4.66 ± 1.80 versus 5.10 ± 2.04 dB).Conclusions. The use of Bangerter filters leads to a reduction of the functionality of the magno- and parvocellular pathway.

Rarebit Perimetry and Frequency Doubling Technology in Patients with Ocular Hypertension

2008 ◽  
Vol 18 (2) ◽  
pp. 205-211 ◽  
Author(s):  
G. Corallo ◽  
M. Iester ◽  
R. Scotto ◽  
G. Calabria ◽  
C.E. Traverso
Keyword(s):  
Ocular Hypertension ◽  
Frequency Doubling ◽  
Control Group ◽  
Mean Deviation ◽  
Automated Perimetry ◽  
Standard Automated Perimetry ◽  
Additional Advantage ◽  
Frequency Doubling Technology ◽  
Increased Risk ◽  
The Mean

Purpose To test the capability of rarebit perimetry (RP), a recent non-conventional perimetric technique, in detecting early functional damage in subjects with ocular hypertension (OHT) and to compare RP findings with those obtained by frequency-doubling technology (FDT) perimetry. Methods Thirty patients with OHT were matched with 30 healthy subjects. All were tested with RP and FDT. Frequency-doubling technology mean deviation (MD) and pattern standard deviation (PSD), as well as RP mean hit rate (MHR), of the two groups were analyzed. The agreement between the two techniques was tested by Kappa analysis. Results In the OHT group the mean (SD) FDT MD was 0.5 (2.1), the mean (SD) FDT PSD was 4.2 (1.6), and the mean (SD) RP MHR was 81.4 (6.7). In the control group, corresponding values were mean (SD) FDT MD 1.1 (1.4), mean (SD) FDT PSD 3.0 (0.3), mean (SD) RP MHR 96.2 (2.0). The differences between the two groups were not significant for the studied indexes. Eleven (36.6%) out of the 30 OHT eyes had abnormal RP results; 12 (40.0%) eyes had abnormal FDT results. Five (16.6%) eyes had abnormal RP and FDT findings. Only 1 eye (3.3%) in the control group had abnormal RP results and 3 eyes (10.0%) had abnormal FDT results. RP and FDT showed a moderate agreement (Kappa = 0.43; 95% CI: 0.42 to 0.51). Conclusions RP and FDT showed VF defects not shown in standard automated perimetry in the OHT group. This may be indicative of an increased risk in developing glaucoma, even if a gold standard for detecting subtle defects is not currently available. RP has the additional advantage of not requiring any expensive device to be used. The poor agreement between these techniques in identifying eyes with early damage warrants further investigations. Large longitudinal studies are needed before defining the role of RP in early glaucoma diagnosis.

IMMUNOREACTIVE GROWTH HORMONE IN PLASMA AND URINE IN JUVENILE DIABETICS BEFORE AND DURING INITIAL INSULIN TREATMENT

1974 ◽  
Vol 75 (1) ◽  
pp. 50-63 ◽  
Author(s):  
Kristian F. Hanssen
Keyword(s):  
Growth Hormone ◽  
Insulin Treatment ◽  
Juvenile Diabetes ◽  
Control Group ◽  
List Type ◽  
Newly Diagnosed ◽  
Renal Tubular Reabsorption ◽  
Juvenile Diabetics ◽  
The Mean ◽  
Renal Tubular

ABSTRACT Twenty newly diagnosed, but as yet untreated patients of both sexes with classical juvenile diabetes were investigated by determining the mean plasma immunoreactive growth hormone (IRHGH) and urinary IRHGH for a 24 hour period before and during initial insulin treatment. The plasma IRHGH was significantly higher (0.05 > P > 0.01) before than during initial insulin treatment. During initial insulin treatment, the mean plasma IRHGH was significantly higher (0.01 > P > 0.001) than in a control group. The urinary IRHGH was significantly higher (0.01 > P > 0.001) before than during insulin treatment. The increased urinary IRHGH observed before insulin treatment is thought to be partly due to a defective renal tubular reabsorption of growth hormone. No significant correlation was found between the mean blood sugar and plasma or urinary IRHGH either before or during insulin treatment.

THE EFFECT OF APPLYING ANIMAL CARTOON PICTURES ON STUDENTS’ ACHIEVEMENT IN WRITING NARRATIVE TEXT

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Hasanul Arifin Zul And Masitowarni Siregar
Keyword(s):  
T Test ◽  
Narrative Text ◽  
Control Group ◽  
First Year ◽  
Writing Achievement ◽  
Control Groups ◽  
Post Test ◽  
Written Test ◽  
And Control ◽  
Experimental Group

This thesis is focused on the investigation of the effect of applying animal cartoon pictures on students’ achievement in writing narrative text. This study aims to find whether applying animal cartoon pictures significantly affect the students’ writing achievement or not. The data in this study were obtained by administering a written test. The population was the 2015/2016 first year (grade XI) of SMA Swasta Nusantara Lubuk Pakam and 66 students were taken as the sample by using random sampling. The sample was divided into two groups, experimental and control groups. The experimental group was taught by applying animal cartoon pictures while the control group without animal cartoon pictures (x = lecturing). The data were taken the scores from the pre-test and post-test to both experimental and control groups. These data were analyzed by using t-test. The result of computing the t-test obviously showed that t-observed is higher than t-table (5.21 >1,67) with the degree of freedom 64 (df =N-2) at the level significance 0,05 one tail test. It showed that the application of animal cartoon pictures significantly affected the students of SMA Swasta Nusantara Lubuk Pakam achievement in writing narrative text.

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