Pharmacognostic and analytical assessment for Pterolobium hexapetalum (Roth.) Santapau and Wagh. – A dynamic Folklore therapeutic plant

2020 ◽  
Vol 11 (3) ◽  
pp. 3338-3348
Author(s):  
Sharmila S ◽  
Dhivya S M ◽  
Akilandeswari D ◽  
Mownika S ◽  
Ramya E K
Keyword(s):  
Chemical Constituents ◽  
Folk Medicine ◽  
Fluorescence Analysis ◽  
Healthy Plant ◽  
Phytochemical Analysis ◽  
Bioactive Constituents ◽  
Plant Materials ◽  
Chemical Reagents ◽  
Analytical Assessment ◽  
Study Species

The aim of the current study was to assess a scrupulous pharmacognostic cram is to enhance the constructive information with regard to its species identification, characterization and standardization of a dynamic folklore therapeutic plant Pterolobium hexapetalum. It is one of the largest scrambling shrubs belonging to the Leguminosae family having significant medicinal properties. The aerial part of the fresh and healthy plant materials was collected from the Maruthamalai hill, Coimbatore District with a strong traditional background. The confined name of the species is “Karuindu” used as medicine in Siddha, Ayurveda and folk medicine for treating various illnesses. The external morphology of study species, the anatomy of leaf and stem, physicochemical examination of plant powder, powder with diverse chemical reagents, fluorescence analysis of therapeutic powder, ash values, mineral studies, heavy metal analysis, extractive values, phytochemical analysis, GCMS analytical studies were examined with the aim of drafting pharmacopeial principles. The studied plant contains 19 bioactive chemical constituents which confirm the healing domination. The analytical assessment of study species authenticates the presence of various bioactive constituents with a broad range of remedial properties which is used to treat manifold muddle as well it provides a comprehensive insight regarding the phytoconstituents profile which could be browbeaten for the maturity of plant-supported drugs.

scholarly journals Phytochemical analysis of successive extracts of the Cordia macleodii leaves Hook.: A Folklore medicinal plant

2018 ◽  
Vol 4 (1) ◽  
pp. 14-17
Author(s):  
Gamit Rakesh ◽  
◽  
Patel Amit G ◽  
VJ Shukla ◽  
MB Nariya ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Uv Light ◽  
Biological Activities ◽  
Petroleum Ether Extract ◽  
Fluorescence Analysis ◽  
Phytochemical Analysis ◽  
Unsaponifiable Fraction ◽  
Ether Extract ◽  
Chemical Reagents ◽  
Chloroform Methanol

‘Preliminary phytochemical analysis of successive extracts, fluorescence analysis and HPTLC of C. macleodiileaves has been planned in the current study.’ The extracts of the dried coarse powdered of C. macleodii leaves obtained using different polarities solventsin succession were tested for the presence of various active phytoconstituents. Fluorescence analysis was investigated andunsaponifiable fraction of petroleum ether extract was also observed forchromatographic evaluations. The outcome suggest that the existence of various dynamic phytoconstituents having particular solubility in selected solvents of different polarities used in succession. The fluorescent analysis under the visible and UV light by treatment of diverse chemical reagents showed diverse colours. HPTLC profile of unsaponifiable fraction showed 10 and 3 spots at 254 nm and 366 nm radiation respectively. After spraying with diluted H2SO4, it showed 5 and 6 spots at 254 nm and 366 nm radiations respectively. The presence of active constituents in different polarities solvent, which were used in progression suggesting the significance of the solvent as a conclusive factor. Further the data suggests that, the successive extractions using Petroleum ether, chloroform, methanol and water solvents of different polarities would maximize the exploitation of the diverse bioactive compounds. Study concluded that it would be help to isolate and characterize the different pharmacologically dynamic principles of the C. macleodii such as mouth sores, treating jaundice, hepatoprotective and also as an aphrodisiac. It shows their importance for supporting their claimed uses and biological activities such as wound healing.

scholarly journals FLUORESCENCE ANALYSIS, PHYTOCHEMICAL, AND ANTIOXIDANT ACTIVITIES IN LEAVES AND STEM OF EMBELIA RIBES BURM. F

2019 ◽  
pp. 225-229
Author(s):  
VIDYA V. KAMBLE ◽  
NIKHIL B. GAIKWAD
Keyword(s):  
Methanolic Extract ◽  
Antioxidant Activities ◽  
Ethanolic Extract ◽  
Fluorescence Analysis ◽  
Total Phenolic ◽  
Phytochemical Analysis ◽  
Chemical Reagents ◽  
Embelia Ribes ◽  
Antioxidant Agents ◽  
Total Alkaloid Content

Objective: The objective of the present study is to carry out fluorescence analysis, phytochemical, and antioxidant activities using different solvent extract in leaves and stem of Embelia ribes. Methods: In the present study, fluorescence analysis, phytochemical, and antioxidant activities of leaves and stem of E. ribes are carried out using standard procedures. Result: The fluorescence analysis under visible and ultraviolet light for leaves and stem powder of E. ribes treated with various chemical reagents shown different fluorescence effect. In the phytochemical analysis, the methanolic extract of leaves has shown the highest total alkaloid content (19.05±0.42 mg CE/g DW), followed by the stem. The methanolic extract of stem exhibited highest total phenolic content (59.82±2.98 mg GAE/g DW), and ethanolic extract showed highest total flavonoid content (10.05±0.36 mg RE/g DW), followed by leaves. The ethanolic extract of stem possesses highest antioxidant activity toward 1,1-diphenyl-2-picrylhydrazyl (DPPH) (84.86±0.11%), whereas methanolic extract of stem reported highest FRAP activity (72.22±0.31 mg Fe+2E/g DW), followed by leaves. Antioxidant activities (DPPH and FRAP) were significantly correlated with TPC. Conclusion: The results of the present study revealed that the fluorescence analysis of leaves and stem of E. ribes can be helpful for the standardization and quality control of indigenous drug. Both leaves and stem serve as the good source of secondary metabolite and antioxidant agents.

scholarly journals Evaluation of phytochemical screening and antibacterial activity of ficus auriculata lour. (moraceae) – an traditional medicinal plant

2021 ◽  
Vol 8 (1) ◽  
pp. 22-29
Author(s):  
Rekka Raja ◽  
Nirubama Kumar ◽  
Moorthy Duraisamy
Keyword(s):  
Antibacterial Activity ◽  
Folk Medicine ◽  
Diffusion Method ◽  
Klebsiella Pneumonia ◽  
Zone Of Inhibition ◽  
Bioactive Constituents ◽  
Fruit Extract ◽  
Chemical Reagents ◽  
Wide Range ◽  
Treatment Of Diabetes

Ficus auriculata is a huge tropical, deciduous and evergreen tree is cultivated in India for its edible fruits and also this plant fruits have been used for the treatment of diabetes, asthma, male and female infertility by Malayali tribals in Yercaud hills. The main aim of this study was to screening of phytochemical properties of the fruit of this plant and also evaluated their potency. The investigation of phytochemical has been done by chemical tests and using some chemical reagents and it showed the presence of various classes of compounds such as carbohydrates, glycosides, phenolic compounds and Tannins, alkaloids, proteins and amino acids, flavonoids, saponins, terpenoids, phytosterols and fixed oils and fat and absence of Anthraquinones. This study summarizes the information concerning the bioactive constituents present in methanol fruit extract which may be responsible for various therapeutically effects. Phenol content of the fruit extract was 1.03mg/g dr.wt, flavonoids content of the fruit extract was 0.64mg/g dr. wt., and alkaloids content was 0.15 mg/g dr.wt.  The antibacterial activity of the extracts was established by disc diffusion method and the extract showed a clear zone of inhibition against Proteus vulgaris, Staphylococcus epidermidies, E. coli, Klebsiella pneumonia, Neisseria gonorrhoeae, Mycoplasma genetalium and Pseudonomos aeruginosa. The methanolic fruit extract of the F. auriculata showed a wide range of activity against all the bacterial studied. The zone of inhibition increased with the increase in concentration. Highest activity was seen in Mycoplasma genetalium and Staphylococcus epidermidies in a concentration of 60 µg. the results provide justification for the use of F. auriculata in folk medicine to treat various infectious disease.

scholarly journals Cyperus conglomeratus (Cyperaceae) a halophyte from Gujarat: Physicochemical, Phytochemical and Pharmacognostic studies

2018 ◽  
Vol 7 (3) ◽  
pp. 334-340
Author(s):  
Pande Jyoti ◽  
◽  
Padalia Hemali ◽  
Rokad Nilam ◽  
Chanda Sumitra ◽  
...  
Keyword(s):  
Uv Light ◽  
Fluorescence Analysis ◽  
Surface Characteristics ◽  
Polar Compounds ◽  
Physicochemical Analysis ◽  
Phytochemical Analysis ◽  
Chemical Reagents ◽  
Morphological Studies ◽  
Whole Plant ◽  
Colour Changes

The aim of the present work was evaluation of physicochemical, phytochemical and pharmacognostic parameters of Cyperus conglomeratus an halophyte from Gujarat. The plant belonging to the family Cyperaceae commonly known as Sedge family. The leaf and stem was evaluated macroscopically and microscopically. Preliminary qualitative phytochemical analysis, physicochemical analysis which included loss on drying, ash values and extractive values and fluroscence analysis were done in accordance with WHO guidelines for identification and standardization of C. conglomerates. The morphological studies exhibited the organoleptic and surface characteristics of whole plant like the leaf was simple, alternate, elongated lanceolate, entire margin, acute apex, parallel veination. The microscopic and powder microscopic study showed the presence of various characteristics like parenchyma cells, spiral vessels, annular vessels, parallel venation, gramineous stomata, conjoint collateral vascular bundle, etc. The phytochemical analysis revealed the plant to be rich in steroids and triterpenes. The extractive value was maximum in methanol solvent indicating presence of more polar compounds. The fluorescence analysis under visible light & under UV light by treatment with different chemical reagents showed characteristic colour changes. The standards laid down will be helpful to ensure the efficacy, safety and purity of medicinal halophytic plant C. conglomerates. The parameters established in this study are useful for the preparation of a monograph of this plant

scholarly journals Chemical Constituents of Eremostachys macrophylla Montbr. & Auch. Aerial Parts

2020 ◽  
Vol 26 (2) ◽  
pp. 203-208
Author(s):  
Parina Asgharian ◽  
Abbas Delazar ◽  
Solmaz Asnaashari
Keyword(s):  
High Performance ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Reversed Phase ◽  
Spectroscopic Technique ◽  
Phytochemical Analysis ◽  
Aerial Parts ◽  
Soxhlet Apparatus ◽  
Snake Bites ◽  
Pure Compounds

Background: Eremostachys macrophylla Montbr. & Auch. is one of the wild growing species of herbs found in East Azerbaijan province of Iran. These species are used in folk medicine for the healing of wound, treatment of snake bites, rheumatism and joint pains. The primary aim of this study was to obtain natural pure compounds and this was done by subjecting the aerial parts of Eremostachys macrophylla Montbr. & Auch. to phytochemical analysis. Methods: The air-dried and crushed aerial parts were respectively extracted with n-hexane, dichloromethane (DCM) and methanol (MeOH) solvents using a soxhlet apparatus. The 10%, 20% and 40% of MeOH in water Sep-Pak fractions of the MeOH extract were subjected to a preparative reversed- phase high performance liquid chromatography (RP-HPLC). Also, the isolated pure compounds were identified by one-dimensional nuclear magnetic resonance (1D-NMR) spectroscopic technique. Results: The results obtained in this study showed the presence of seven pure components; (1) Lamalbide, (2) Sesamoside, (3) Phlomiol, (4) Verbascoside, (5) Luteolin-7-O- glucoside, (6) Apigenin-7-O- rutinoside and (7) Kaempferol-3-O- glucoside with iridoid, phenylethanoid and flavonoid structures. Conclusion: The results from the study demonstrated that the aerial parts of E. macrophylla could be a good source of iridoids, phenylethanoids and flavonoids.

scholarly journals Recent Progress on Chemical Constituents and Pharmacological Effects of the Genus Nigella

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Yun Niu ◽  
Li Zhou ◽  
Lijun Meng ◽  
Sitan Chen ◽  
Changyang Ma ◽  
...  
Keyword(s):  
Recent Progress ◽  
Seed Oil ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Seed Extract ◽  
Chemical Component ◽  
Pharmacological Effects ◽  
Bioactive Constituents ◽  
The World ◽  
Hepatoprotective Effects

Seeds of the genus Nigella plants as folk medicine are often used to prevent and treat asthma, diarrhea, dyslipidemia, and other diseases around the world. Pharmacological researches showed that seed extract and seed oil have antibacterial, antioxidant, hypoglycemic, and hepatoprotective effects which attributed to their bioactive constituents such as alkaloids, saponins, flavones, and phenols. This paper has covered recent progresses on chemical and pharmacological researches on these plants, including their compounds and pharmacological effects. It was found that the chemical component researches were focused on the seed oil. Therefore, more attention should be paid to the profile of the whole constituents in the seeds.

Phytochemistry, Pharmacological Activities, Toxicity and Clinical Application of Momordica cochinchinensis

2019 ◽  
Vol 25 (6) ◽  
pp. 715-728 ◽  
Author(s):  
Hai-Yue Lan ◽  
Bin Zhao ◽  
Yu-Li Shen ◽  
Xiao-Qin Li ◽  
Su-Juan Wang ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Southeast Asia ◽  
Clinical Application ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Pharmacological Activities ◽  
Pharmacological Studies ◽  
Momordica Cochinchinensis

Momordica cochinchinensis (Lour.) Spreng (M. cochinchinensis) is a deciduous vine that grows in Southeast Asia. It is known as gac in Vietnam and as Red Melon in English. Gac is reputed to be extremely benificial for health and has been widely used as food and folk medicine in Southeast Asia. In China, the seed of M. cochinchinensis (Chinese name: Mu biezi) is used as traditional Chinese medicine (TCM) for the treatment of various diseases. More than 60 chemical constituents have been isolated from M. cochinchinensis. Modern pharmacological studies and clinical practice demonstrate that some chemical constituents of M. cochinchinensis possess wide pharmacological activities, such as anti-tumor, anti-oxidation, anti-inflammatory, etc. This paper reviews the phytochemistry, pharmacological activities, toxicity, and clinical application of M. cochinchinensis, aiming to bring new insights into further research and application of this ancient herb.

Phytochemistry, Traditional Uses and Pharmacological properties of Enhydra fluctuans Lour: A Comprehensive Review.

2020 ◽  
Vol 21 ◽  
Author(s):  
Antica Barua ◽  
Muhammad Shaiful Alam ◽  
Md. Junaid ◽  
Yeasmin Akter ◽  
Syeda Samira Afrose ◽  
...  
Keyword(s):  
Sesquiterpene Lactone ◽  
Chemical Constituents ◽  
Phytochemical Analysis ◽  
Microbial Infection ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Cns Depressant ◽  
Isoflavone Glycoside ◽  
Online Library ◽  
Pharmacologically Active

Background: Enhydra fluctuans Lour, a tropical herb, commonly known as helencha or harkuch, belonging to family Asteraceae, and is an edible semi-aquatic herbaceous vegetable plant with serrate leaves, grows commonly in different parts of the world. Enhydra fluctuans possesses potential pharmacological role against inflammation, cancer, diarrhea, microbial infection, diabetes, and so on. Aim of the review: This review aims to provide the most current information on the botanical characterization, distribution, traditional uses, chemical constituents, as well as the pharmacological activities of Enhydra fluctuans Lour. Materials and methods: The recently updated information on Enhydra fluctuans was gathered from scientific journals, books, and worldwide accepted scientific databases via a library and electronic search (PubMed, Elsevier, Google Scholar, Springer, Scopus, Web of Science, Wiley online library. All of the full-text articles and abstracts related to Enhydra were screened. The most important and relevant articles were carefully chosen for study in this review. Results: Crude extracts and isolated compounds of Enhydra fluctuans Lour has been reported pharmacologically active against cytoprotective, analgesic and anti-inflammatory, antimicrobial, anticancer, anti-diarrhoeal, antihelmintic, CNS depressant, hepatoprotective, thrombolytic, antidiabetic, anti-oxidant, phagocytic and cytotoxic, and neuroprotective potential activities. Discussion: Phytochemical analysis from different studies has reported Germacranolide, Sesquiterpene lactone, Flavonoid, Essential oil, Steroid, Diterpenoid, Melampolide, Sesquiterpene lactone, Isoflavone glycoside as major compounds of Enhydra fluctuans Lour. Conclusions: However, more research is important to explore the mode of action of bioactive components of the plant and its therapeutic capabilities.

Bryophyllum Pinnatum: A Review on Medicinal Benefits and Potent Bioactive Molecules

2020 ◽  
Vol 16 (7) ◽  
pp. 978-992
Author(s):  
Punit Kumar ◽  
Sujata Malik ◽  
Kashyap K. Dubey
Keyword(s):  
Web Of Science ◽  
Folk Medicine ◽  
Bioactive Molecules ◽  
Phytochemical Analysis ◽  
Traditional Herbal Medicine ◽  
Pharmacological Activities ◽  
Online Databases ◽  
Natural Remedies ◽  
Medicinal Properties ◽  
Bryophyllum Pinnatum

Background: Since its inception, people are using herbal extracts as natural remedies for the treatment of various diseases. Bryophyllum pinnatum, also known as the air plant, is a well-recognized herb used in folk medicine. It is native to Madagascar and further planted in tropical and subtropical areas around the world. It is known for the profusion of miniature plantlets which arise from the margins of phylloclade. Objective: The aim of this review is to provide the information regarding local and traditional uses, pharmacological activities and different phytochemicals reported from leaves extracts of Bryophyllum pinnatum. Methods: This review article contains a detailed survey of the literature about Bryophyllum pinnatum available in different online databases, such as; PubMed, Web of Science, Science Direct, Elsevier, and Google Scholar, etc. In this review, authors have focused on ethnopharmacological importance and phytochemicals present in Bryophyllum pinnatum and their structure. The structures of the phytochemical were prepared by the ChemDraw tool. Results: This plant is used as a traditional herbal medicine around the globe due to medicinal properties like; anthelmintic, immunosuppressive, hepatoprotective, antinociceptive, anti-inflammatory, antidiabetic, nephroprotective, antioxidant, antimicrobial, analgesic, anticonvulsant and antipyretic. Phytochemical analysis revealed the presence of many bioactive compounds like; alkaloids, flavonoids, triterpenes, steroids, glycosides, bufadienolides, lipids, and organic acids, etc. which are associated with different medicinal properties. Conclusion: Bryophyllum pinnatum possesses diverse pharmacological importance and remarkable medicinal properties. Investigators have reported a large number of phytochemicals exhibiting different medicinal properties and correlation of medicinal properties.

Isolation and HPLC Determination of the Chemical Components of Gentianella acuta (Michx.) Hulten

2018 ◽  
Vol 15 (1) ◽  
pp. 21-33
Author(s):  
Ying Wei ◽  
Yongqiao Liu ◽  
Yifan Hele ◽  
Weiwei Sun ◽  
Yang Wang ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
High Speed ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Gradient Elution ◽  
Chemical Components ◽  
Isolation And Characterization ◽  
Major Chemical ◽  
Main Components ◽  
First Time

Background: Gentianella acuta (Michx.) Hulten is an important type of medicinal plant found in several Chinese provinces. It has been widely used in folk medicine to treat various illnesses. However, there is not enough detailed information about the chemical constituents of this plant or methods for their content determination. Objective: The focus of this work is the isolation and characterization of the major chemical constituents of Gentianella acuta, and developing an analytical method for their determination. Methods: The components of Gentianella acuta were isolated using (1) ethanol extraction and adsorption on macroporous resin. (2) and ethyl acetate extraction and high speed countercurrent chromatography. A HPLC-DAD method was developed using a C18 column and water-acetonitrile as the mobile phase. Based on compound polarities, both isocratic and gradient elution methods were developed. Results: A total of 29 compounds were isolated from this plant, of which 17 compounds were isolated from this genus for the first time. The main components in this plant were found to be xanthones. The HPLC-DAD method was developed and validated for their determination, and found to show good sensitivity and reliability. Conclusion: The results of this work add to the limited body of work available on this important medicinal plant. The findings will be useful for further investigation and development of Gentianella acuta for its valuable medicinal properties.

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