scholarly journals Collision Glial Neoplasms Arising in an Ovarian Mature Cystic Teratoma: A Rare Event

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Abdelrazak Meliti ◽  
Bayan Hafiz ◽  
Haneen Al-Maghrabi ◽  
Abdulrahim Gari
Keyword(s):  
Germ Cell ◽  
English Literature ◽  
Rare Event ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Single Type ◽  
Ovarian Teratoma ◽  
Histopathologic Finding ◽  
Children And Young Adults ◽  
Benign Ovarian Neoplasm

Germ cell neoplasms represent around 20% of all ovarian tumors. They most frequently affect children and young adults. Mature cystic teratoma is a common benign ovarian neoplasm comprising about 95% and is made up of all three germ cell embryonic layers. By definition, mature cystic teratoma may be derived from any of the three germ cell lines. On the other hand, immature teratomas contain primitive neuroepithelial elements. However, it is quite uncommon in the English literature to have a neuroepithelial glial neoplasm arising in a mature cystic teratoma of an adolescent. Interestingly enough, all published cases described a single type of glial neoplasm arising in mature ovarian teratoma. Herein, the authors discuss a unique case of concomitant occurrence of two different glial neoplasms, namely pilocytic astrocytoma and subependymoma arising in an ovarian mature cystic teratoma. To the best of our knowledge, this is the first reported case with such a distinctive histopathologic finding.

OVARIAN MATURE CYSTIC TERATOMA WITH TRANSFORMATION INTO SQUAMOUS CELL CARCINOMA: REPORT OF TWO CASES

2021 ◽  
pp. 38-39
Author(s):  
Supriya Pradhan ◽  
Bhuvan Adhlakha ◽  
Vijay D Dombale
Keyword(s):  
Squamous Cell Carcinoma ◽  
Germ Cell ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Squamous Cell ◽  
Germ Cell Tumors ◽  
Rare Event ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma

Ovarian mature cystic teratomas are the commonest germ cell tumors of the ovary. Malignant transformation in them is a rare event and is difcult to diagnose preoperatively. Clinicians, pathologists and radiologists should always suspect this if the patient is elderly or when the cyst is large or in presence of a solid foci. Here, we discuss two cases of squamous cell carcinoma arising from a mature cystic teratoma

Dermoid Cyst (Mature Cystic Teratoma) of the Cecum

2002 ◽  
Vol 126 (1) ◽  
pp. 97-99 ◽  
Author(s):  
Maurice Joseph Schuetz ◽  
Tarik M. Elsheikh
Keyword(s):  
Gastrointestinal Tract ◽  
Fine Needle Aspiration ◽  
Close Association ◽  
English Literature ◽  
Abdominal Mass ◽  
Cystic Teratoma ◽  
Needle Aspiration ◽  
Mature Cystic Teratoma ◽  
Fine Needle ◽  
Pathologic Features

Abstract The gastrointestinal tract is an unusual site for teratomas to occur. Only 4 prior cases of teratomas involving the cecum have appeared in the English literature, the latest published in 1977. To the best of our knowledge, this is the first report to describe fine-needle aspiration cytologic findings in addition to histologic features of a mature cystic teratoma involving the gastrointestinal tract. A 30-year-old man presented with right upper quadrant abdominal pain and a palpable abdominal mass. Radiographic studies identified a mass lesion inferior to the liver and in close association with the ascending colon. Fine-needle aspiration biopsy showed scant keratinous material and anucleated squamous cells. Right colectomy revealed a cystic mass in the wall of the cecum that contained keratinous material and was lined by stratified granular squamous epithelium with sebaceous glands. Clinical and pathologic features with review of the literature are presented, and the differential diagnosis for pericolic cystic masses is discussed in detail.

scholarly journals Intestinal Adenocarcinoma Arising from a Mature Cystic Teratoma

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
King Man Wan ◽  
Forough Foroughi ◽  
Rajni Bansal ◽  
Martin K. Oehler
Keyword(s):  
Germ Cell ◽  
Incidence Rate ◽  
Clinical Presentation ◽  
Ovarian Neoplasms ◽  
Germ Cell Tumour ◽  
Cystic Teratoma ◽  
Squamous Cell Carcinomas ◽  
Mature Cystic Teratoma ◽  
Histopathological Diagnosis ◽  
Common Malignancy

Mature cystic teratomas are the most common ovarian germ cell tumour and account for 10–20% of all ovarian neoplasms. Malignant transformation of mature cystic teratomas is rare and has an incidence rate of less than 1%. The most common malignancy are squamous cell carcinomas. Here we present the case of an intestinal adenocarcinoma which is an exceedingly rare malignant entity arising within a mature cystic teratoma. Clinical presentation, imaging and histopathological diagnosis are discussed and previously presented cases in the literature reviewed.

Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor

2018 ◽  
Vol 54 (12) ◽  
pp. 629-630
Author(s):  
Ana Vallejo-Benítez ◽  
Enrique Rodríguez-Zarco ◽  
Sofia Pereira-Gallardo ◽  
Laura Macías-García
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Cystic Teratoma ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Mature Cystic Teratoma ◽  
Testicular Germ Cell

Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor

2018 ◽  
Vol 54 (12) ◽  
pp. 629-630
Author(s):  
Ana Vallejo-Benítez ◽  
Enrique Rodríguez-Zarco ◽  
Sofia Pereira-Gallardo ◽  
Laura Macías-García
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Cystic Teratoma ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Mature Cystic Teratoma ◽  
Testicular Germ Cell

Coexistence of endometriosis in women with mature cystic ovarian teratoma may not be rare.

2020 ◽  
Author(s):  
Heesuk Chae
Keyword(s):  
Early Stage ◽  
Cystic Teratoma ◽  
Operation Time ◽  
Mature Cystic Teratoma ◽  
Ovarian Teratoma ◽  
Advanced Stage ◽  
Clinicopathologic Features ◽  
Complex Group ◽  
The Mean ◽  
Group Serum

Abstract Background We investigated the incidence of endometriosis in women with mature cystic ovarian teratoma and analyzed the clinicopathologic features of this occurrence. Methods From January 2017 through December 2018, we retrospectively studied 71 women who had undergone cystectomy for mature cystic ovarian teratoma (n = 55, teratoma group) and coexistence of endometriosis and mature cystic ovarian teratoma (n = 16, complex group). Serum anti-Müllerian hormone (AMH) levels were measured preoperatively and one month after surgery. Results Sixteen (22.54%) patients had coexistence of endometriosis and mature cystic ovarian teratoma (complex group); 55 patients had mature cystic teratoma alone (teratoma group). Early-stage endometriosis (stage I) was present in eight patients and advanced-stage endometriosis (stage III or IV) was present in eight. In five cases (31.25%), the coexistence of endometrioma and mature cystic teratoma in the same ovary was observed. The mean operation time was significantly shorter in the teratoma group than in the complex group (61.02 ± 22.74 vs. 86.31 ± 35.35 min, p = 0.007). The complex group had more dysmenorrhea (43.8% vs. 7.3%, p = 0.002) and a significantly higher rate of decrease in serum anti-Müllerian hormone (AMH) levels (33.06 ± 24.92 vs. 16.31 ± 28.17%, p = 0.048). Conclusion(s) The prevalence of coexisting endometriosis and mature cystic ovarian teratoma may be underestimated. Patients with this rare concurrence may present with worsening dysmenorrhea and damage to ovarian reserve after surgery may be greater in patients with coexisting endometriosis than in patients with mature cystic teratoma alone.

scholarly journals Ovarian Germ Cell Tumor – Histopathological and statistical analysis

2013 ◽  
Vol 3 (6) ◽  
pp. 441-446
Author(s):  
A Ghosh ◽  
D Magar Gharti ◽  
B Sathian ◽  
R Narasimhan ◽  
Op Talwar
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Malignant Tumors ◽  
Germ Cell Tumors ◽  
Cystic Teratoma ◽  
Cell Tumor ◽  
Ovarian Tumors ◽  
Mature Cystic Teratoma ◽  
Age Group ◽  
Malignant Germ Cell Tumors

Background: Ovarian cancers are common among females. The ovarian tumors are classified according to its histogenesis. In the present study, we analyzed the germ cell ovarian tumors reported in our institute. Materials and Methods: This study was a hospital based retrospective study. All ovarian germ cell tumor reported from Jan 2001 to Feb 2013 were retrieved and analyzed. The specimens were routinely processed and the slides were stained with H&E and special stains wherever required. Results: A total of 340 cases of ovarian tumors were reported and 150 cases (44%) were of germ cell origin. We had 137 cases of benign and 13 cases of malignant germ cell tumors. Most common subtype was mature cystic teratoma comprising 125 cases. Among the malignant cases, the most common was immature teratoma (5 cases). Age range in our series was from 8 to 82 years (mean 28 years). The most common age group affected was 21-30 years. Most of the malignant cases (76.9%) were in less than 30 years. Among the malignant cases majority (84.6%) were more than 10 cm in size. None of the malignant germ cell tumors were bilateral. Conclusion: Among germ cell tumors of ovary, mature cystic teratoma is the most common tumor and malignant subtypes are uncommon. Malignant tumors tend to occur in younger age group. DOI: http://dx.doi.org/10.3126/jpn.v3i6.8990 Journal of Pathology of Nepal (2013) Vol. 3, 441-446

scholarly journals Ovarian teratomas: clinicopathological study at tertiary care center

2019 ◽  
Vol 8 (8) ◽  
pp. 3318
Author(s):  
Sunil Vitthalrao Jagtap ◽  
Nitin S. Kshirsagar ◽  
Shubham S. Jagtap ◽  
Saswati Boral ◽  
Nitesh Nasre
Keyword(s):  
Germ Cell ◽  
Histopathological Examination ◽  
Mature Teratoma ◽  
Tertiary Care ◽  
Germ Cell Tumors ◽  
Cystic Teratoma ◽  
Ovarian Teratoma ◽  
Care Hospital ◽  
Palpable Mass ◽  
Ovarian Teratomas

Background: Teratomas are belonging to a group of germ cell tumors. It is also referred to as dermoid cyst. Teratomas are most common germ cell tumor of the ovary. Teratomas are composed of various histological types. In this article we are presenting various morphological patterns, its clinical manifestation and its clinical significance.Methods: This is prospective study for a period of 3 years from March 2016 to February 2019 at tertiary care hospital. It consists of total evaluation of 82 cases of ovarian lesions which were surgically excised for clinically or radiologically suspected of ovarian neoplasm.Results: A total of 82 cases of ovarian specimen were included out of which 18 cases were of ovarian teratoma. In these 17 cases were benign teratomas, 1 case of immature teratoma. All the cases of mature teratoma were predominantly of cystic type with focal solid areas. Right sided ovary was involved in44.5% cases while left sided in 55.5% cases. The tumor size ranges from 2.5 cm to 20.8 cms. The age range in this study was from 20 to 60 year. The common age observed for ovarian teratoma was in group of 31-40 years, having 6 cases. The clinically most of cases were asymptomatic or presented with unexplained abdominal pain or palpable mass. USG finding in most of cases were diffuse or partial echogenic mass lesion with cystic nature and echogenic bands.Conclusions: In our study showed mature cystic teratoma is the most common type of ovarian teratomas. The immature and monodermal types are rare. The histopathological examination plays important role in final diagnosis   and patient management.

scholarly journals Successful Laparoscopic Resection of 7 mm Ovarian Mature Cystic Teratoma Associated with Anti-NMDAR Encephalitis

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Masaru Hayashi ◽  
Emi Motegi ◽  
Koichi Honma ◽  
Nobuhide Masawa ◽  
Hideki Sakuta ◽  
...  
Keyword(s):  
Cystic Teratoma ◽  
Antibody Test ◽  
Mature Cystic Teratoma ◽  
Ovarian Teratoma ◽  
Cystic Tumor ◽  
Macroscopic Appearance ◽  
Abdominal Image ◽  
Nmdar Encephalitis ◽  
Disturbance Of Consciousness ◽  
The Right

Anti-NMDAR (N-methyl-D-aspartate receptor) encephalitis is an immune-mediated encephalitis. It has been predominantly described in young women and is commonly associated with an ovarian teratoma. We report a case of anti-NMDAR encephalitis associated with a 7 mm ovarian teratoma that was completely resected by laparoscopic surgery. An 18-year-old woman suddenly presented with personality changes requiring her admission to the department of neurology. After that, she also showed involuntary movements, disturbance of consciousness, and central hypoventilation. As an abdominal image revealed the possibility of a right ovarian teratoma of5×7 mm, a laparoscopic operation was performed. The macroscopic appearance of the right ovary did not show any abnormalities; nevertheless, we performed a partial resection of the right ovary, with reference to the image diagnosis, in order to spare the ovarian reserve. The22×22 mm partially resected ovary contained an intact5×7 mm cystic tumor. The pathological diagnosis was mature cystic teratoma with components of brain tissue. An anti-NMDAR-antibody test proved positive in both serum and cerebrospinal fluid 1 month after the surgery. From these results, she was diagnosed with anti-NMDAR encephalitis. By the administration of cyclophosphamide in addition to the operation, she recovered drastically without any of the symptoms shown before.

scholarly journals Mature Ovarian Teratoma with Carcinoid Tumor in a 28-Year-Old Patient

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Stamatios Petousis ◽  
Ioannis Kalogiannidis ◽  
Chrysoula Margioula-Siarkou ◽  
Alexandros Traianos ◽  
Dimosthenis Miliaras ◽  
...  
Keyword(s):  
Ct Scan ◽  
Carcinoid Tumor ◽  
Surgical Approach ◽  
Pap Smear ◽  
Cystic Teratoma ◽  
Mature Cystic Teratoma ◽  
Ovarian Teratoma ◽  
Ovarian Mass ◽  
Gynecological Examination ◽  
Gastric Type

Introduction. Coexistence of carcinoid tumor inside a mature cystic teratoma is an extremely rare phenomenon, especially in young women. We present the case of a 28-year-old woman diagnosed with a right ovarian carcinoid and treated uneventfully with conservative surgical approach.Case Report. A 28-year-old woman, gravid 0, parity 0, presented to our department for her annual gynecological examination and Pap smear test. During her examination, a mobile cystic mass was detected in the right lower abdomen. Ultrasound indicated a right ovarian mass 10.5 × 6.3 cm, confirmed by CT scan. Further investigation revealed AFP levels (1539 ng/mL). The ovarian mass was excised by laparoscopy, leaving intact the remaining right ovary. Frozen sections showed a mature cystic teratoma. However, paraffin sections revealed the presence of a small carcinoid within the teratoma’s gastric-type mucosa. The patient was set to a close followup. Nine months postoperatively, ultrasound pelvis imaging and CT scan of the abdomen as well as serum tumor markers have shown no evidence of recurrence disease.Conclusion. Despite the weak evidence, fertility spare surgical approach for women wanting to preserve their genital tract might be a reasonable option.

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