scholarly journals Influence of Rib Cage on Static Characteristics of Scoliotic Spine

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Liying Lin ◽  
Shaowei Jia ◽  
Hufei Yang ◽  
Ye Li ◽  
Shunxin Zhang ◽  
...  

Background. Scoliosis is a three-dimensional (3D) deformity of the spine, which affects the patient’s appearance and may lead to abnormal heart and lung function. The rib cage is a structure composed of ribs, sternum, and costal cartilage, which plays a vital role in stabilising the thoracolumbar spine. This study investigates the influence of the rib cage on the static characteristics of the scoliotic spine. Methods. Two types of 3D finite element (FE) models with or without rib cage (from T1 to S) were established and analysed based on computed tomography (CT) images, to determine the effects of the rib cage on the static characteristics of the scoliotic spine. The FE software, ABAQUS, was used to analyse the static behaviours of scoliotic spine models under a range of loading conditions, including left side bending, right side bending, front tilt, rear supine, and vertical compression. The changes in the von Mises stress (VMS) within the intervertebral discs of spine models with or without rib cage were studied and compared. Results. After including the rib cage, the maximum VMS at the stress concentrations of the normal and scoliotic spine effectively reduced. The VMS in normal intervertebral discs was gentler than that of scoliotic ones. However, the scoliotic spine was more likely to produce large stress concentration in the intervertebral discs of scoliotic segments. Conclusions. Under the common postures, intervertebral discs of scoliotic segments are more susceptible to generate stress concentrations compared with the normal spine. The rib cage could effectively keep the intervertebral discs of scoliotic segments from further injuries. These results are of great significance for the prevention and treatment of the scoliotic spine.

2020 ◽  
Vol 14 (01) ◽  
pp. 107-114
Author(s):  
Mohamed Ahmed Abdel Hakim ◽  
Nagwa Mohamed Ali Khatab ◽  
Kareem Maher Gaber Mohamed ◽  
Ahmad Abdel Hamid Elheeny

Abstract Objectives This study aims to compare the stress distribution and displacement that resulted from the use of a Gerber space regainer and sagittal distalizer using three-dimensional finite element analysis. Materials and Methods Three-dimensional simulated models of the appliances were developed using a software. The forces applied by the two appliances were 3N (tipping) and 15N (bodily), respectively. Displacement and von Mises stress on the compact and cancellous bone, periodontal ligament (PDL), crowns of the mandibular first, second permanent molars, and deciduous canines were calculated. Stress distribution and displacement values were measured via linear static analysis. Results Gerber space regainer showed greater displacement than that produced by the sagittal distalizer at the first permanent molar. However, such displacement was less at the other tested points when compared with that delivered by sagittal distalizer. The stresses created by Gerber appliance were higher in the crown and PDL of the deciduous canine than the crown of the first permanent molar crown. Conclusions Gerber appliance generates more distal force and less stress concentration on the crown of the mandibular first permanent molar than that created by the sagittal distalizer. On the other hand, stress concentrations produced by Gerber space regainer are found to be more on the crown and PDL of the deciduous canine. Therefore, it can be concluded that the use of Gerber appliance needs more anchorage.


1997 ◽  
Vol 83 (5) ◽  
pp. 1531-1537 ◽  
Author(s):  
A. De Groote ◽  
M. Wantier ◽  
G. Cheron ◽  
M. Estenne ◽  
M. Paiva

De Groote, A., M. Wantier, G. Cheron, M. Estenne, and M. Paiva. Chest wall motion during tidal breathing. J. Appl. Physiol. 83(5): 1531–1537, 1997.—We have used an automatic motion analyzer, the ELITE system, to study changes in chest wall configuration during resting breathing in five normal, seated subjects. Two television cameras were used to record the x-y-z displacements of 36 markers positioned circumferentially at the level of the third (S1) and fifth (S2) costal cartilage, corresponding to the lung-apposed rib cage; midway between the xyphoid process and the costal margin (S3), corresponding to the abdomen-apposed rib cage; and at the level of the umbilicus (S4). Recordings of different subsets of markers were made by submitting the subject to five successive rotations of 45–90°. Each recording lasted 30 s, and three-dimensional displacements of markers were analyzed with the Matlab software. At spontaneous end expiration, sections S1–3 were elliptical but S4 was more circular. Tidal changes in chest wall dimensions were consistent among subjects. For S1–2, changes during inspiration occurred primarily in the cranial and ventral directions and averaged 3–5 mm; displacements in the lateral direction were smaller (1–2 mm). On the other hand, changes at the level of S4 occurred almost exclusively in the ventral direction. In addition, both compartments showed a ventral displacement of their dorsal aspect that was not accounted for by flexion of the spine. We conclude that, in normal subjects breathing at rest in the seated posture, displacements of the rib cage during inspiration are in the cranial, lateral outward, and ventral directions but that expansion of the abdomen is confined to the ventral direction.


2016 ◽  
Vol 10 (03) ◽  
pp. 413-418 ◽  
Author(s):  
Selma Jakupović ◽  
Ivica Anić ◽  
Muhamed Ajanović ◽  
Samra Korać ◽  
Alma Konjhodžić ◽  
...  

ABSTRACT Objective: The present study aims to investigate the influence of presence and shape of cervical lesions on biomechanical behavior of mandibular first premolar, subjected to two types of occlusal loading using three-dimensional (3D) finite element method (FEM). Materials and Methods: 3D models of the mandibular premolar are created from a micro computed tomography X-ray image: model of sound mandibular premolar, model with the wedge-shaped cervical lesion (V lesion), and model with saucer-shaped cervical lesion (U lesion). By FEM, straining of the tooth tissues under functional and nonfunctional occlusal loading of 200 (N) is analyzed. For the analysis, the following software was used: CTAn program 1.10 and ANSYS Workbench (version 14.0). The results are presented in von Mises stress. Results: Values of calculated stress in all tooth structures are higher under nonfunctional occlusal loading, while the functional loading is resulted in homogeneous stress distribution. Nonfunctional load in the cervical area of sound tooth model as well as in the sub-superficial layer of the enamel resulted with a significant stress (over 50 [MPa]). The highest stress concentration on models with lesions is noticed on the apex of the V-shaped lesion, while stress in saucer U lesion is significantly lower and distributed over wider area. Conclusion: The type of the occlusal teeth loading has the biggest influence on cervical stress intensity. Geometric shape of the existing lesion is very important in the distribution of internal stress. Compared to the U-shaped lesions, V-shaped lesions show significantly higher stress concentrations under load. Exposure to stress would lead to its progression.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Shaowei Jia ◽  
Liying Lin ◽  
Hufei Yang ◽  
Jie Fan ◽  
Shunxin Zhang ◽  
...  

Abstract The thoracic cage plays an important role in maintaining the stability of the thoracolumbar spine. In this study, the influence of a rib cage on static and dynamic responses in normal and scoliotic spines was investigated. Four spinal finite element (FE) models (T1–S), representing a normal spine with rib cage (N1), normal spine without rib cage (N2), a scoliotic spine with rib cage (S1) and a scoliotic spine without rib cage (S2), were established based on computed tomography (CT) images, and static, modal, and steady-state analyses were conducted. In S2, the Von Mises stress (VMS) was clearly decreased compared to S1 for four bending loadings. N2 and N1 showed a similar VMS to each other, and there was a significant increase in axial compression in N2 and S2 compared to N1 and S1, respectively. The U magnitude values of N2 and S2 were higher than in N1 and S1 for five loadings, respectively. The resonant frequencies of N2 and S2 were lower than those in N1 and S1, respectively. In steady-state analysis, maximum amplitudes of vibration for N2 and S2 were significantly larger than N1 and S1, respectively. This study has revealed that the rib cage improves spinal stability in vibrating environments and contributes to stability in scoliotic spines under static and dynamic loadings.


2003 ◽  
Vol 07 (02) ◽  
pp. 151-156
Author(s):  
Etsuo Chosa ◽  
Koji Totoribe ◽  
Naoya Tajima

This study evaluated the influence of head mass on the acceleration of the head and neck complex in automobile rear-end collisions using a three-dimensional finite element method. The geometry of the finite element model is based on a cervical (C2–7) motion segment of a 20-year-old man that was obtained by computed tomography. Four types of models were prepared by changing the parameters of mass for an examination of the effects of head mass. Simulated loads were applied at the lower end of the C7 vertebra, with the axial direction constrained. Each model was loaded, and the head acceleration and distribution of von Mises stress were analyzed. Stress was observed to concentrate on the C2/3, C5/6 and C6/7 intervertebral discs. With a large head mass, the delay of the initial rise of the acceleration curve was large and the value of acceleration was small. On the contrary, when the head mass was small, the acceleration curve started to rise earlier. The acceleration curve of the model with the head mass of 1.0 kg was the closest to that of the experiments by Severy. Head mass is an important factor which influences the dynamic response of the head in rear-end collisions.


Author(s):  
M.B. Braunfeld ◽  
M. Moritz ◽  
B.M. Alberts ◽  
J.W. Sedat ◽  
D.A. Agard

In animal cells, the centrosome functions as the primary microtubule organizing center (MTOC). As such the centrosome plays a vital role in determining a cell's shape, migration, and perhaps most importantly, its division. Despite the obvious importance of this organelle little is known about centrosomal regulation, duplication, or how it nucleates microtubules. Furthermore, no high resolution model for centrosomal structure exists.We have used automated electron tomography, and reconstruction techniques in an attempt to better understand the complex nature of the centrosome. Additionally we hope to identify nucleation sites for microtubule growth.Centrosomes were isolated from early Drosophila embryos. Briefly, after large organelles and debris from homogenized embryos were pelleted, the resulting supernatant was separated on a sucrose velocity gradient. Fractions were collected and assayed for centrosome-mediated microtubule -nucleating activity by incubating with fluorescently-labeled tubulin subunits. The resulting microtubule asters were then spun onto coverslips and viewed by fluorescence microscopy.


Author(s):  
Nurullah Türker ◽  
Hümeyra Tercanlı Alkış ◽  
Steven J Sadowsky ◽  
Ulviye Şebnem Büyükkaplan

An ideal occlusal scheme plays an important role in a good prognosis of All-on-Four applications, as it does for other implant therapies, due to the potential impact of occlusal loads on implant prosthetic components. The aim of the present three-dimensional (3D) finite element analysis (FEA) study was to investigate the stresses on abutments, screws and prostheses that are generated by occlusal loads via different occlusal schemes in the All-on-Four concept. Three-dimensional models of the maxilla, mandible, implants, implant substructures and prostheses were designed according to the All-on-Four concept. Forces were applied from the occlusal contact points formed in maximum intercuspation and eccentric movements in canine guidance occlusion (CGO), group function occlusion (GFO) and lingualized occlusion (LO). The von Mises stress values for abutment and screws and deformation values for prostheses were obtained and results were evaluated comparatively. It was observed that the stresses on screws and abutments were more evenly distributed in GFO. Maximum deformation values for prosthesis were observed in the CFO model for lateral movement both in the maxilla and mandible. Within the limits of the present study, GFO may be suggested to reduce stresses on screws, abutments and prostheses in the All-on-Four concept.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Niksa Mohammadi Bagheri ◽  
Mahmoud Kadkhodaei ◽  
Shiva Pirhadi ◽  
Peiman Mosaddegh

AbstractThe implementation of intracorneal ring segments (ICRS) is one of the successfully applied refractive operations for the treatment of keratoconus (kc) progression. The different selection of ICRS types along with the surgical implementation techniques can significantly affect surgical outcomes. Thus, this study aimed to investigate the influence of ICRS implementation techniques and design on the postoperative biomechanical state and keratometry results. The clinical data of three patients with different stages and patterns of keratoconus were assessed to develop a three-dimensional (3D) patient-specific finite-element model (FEM) of the keratoconic cornea. For each patient, the exact surgery procedure definitions were interpreted in the step-by-step FEM. Then, seven surgical scenarios, including different ICRS designs (complete and incomplete segment), with two surgical implementation methods (tunnel incision and lamellar pocket cut), were simulated. The pre- and postoperative predicted results of FEM were validated with the corresponding clinical data. For the pre- and postoperative results, the average error of 0.4% and 3.7% for the mean keratometry value ($$\text {K}_{\text{mean}}$$ K mean ) were predicted. Furthermore, the difference in induced flattening effects was negligible for three ICRS types (KeraRing segment with arc-length of 355, 320, and two separate 160) of equal thickness. In contrast, the single and double progressive thickness of KeraRing 160 caused a significantly lower flattening effect compared to the same type with constant thickness. The observations indicated that the greater the segment thickness and arc-length, the lower the induced mean keratometry values. While the application of the tunnel incision method resulted in a lower $$\text {K}_{\text{mean}}$$ K mean value for moderate and advanced KC, the induced maximum Von Mises stress on the postoperative cornea exceeded the induced maximum stress on the cornea more than two to five times compared to the pocket incision and the preoperative state of the cornea. In particular, an asymmetric regional Von Mises stress on the corneal surface was generated with a progressive ICRS thickness. These findings could be an early biomechanical sign for a later corneal instability and ICRS migration. The developed methodology provided a platform to personalize ICRS refractive surgery with regard to the patient’s keratoconus stage in order to facilitate the efficiency and biomechanical stability of the surgery.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Chaojian Chen ◽  
Manjesh Kumar Singh ◽  
Katrin Wunderlich ◽  
Sean Harvey ◽  
Colette J. Whitfield ◽  
...  

AbstractThe creation of synthetic polymer nanoobjects with well-defined hierarchical structures is important for a wide range of applications such as nanomaterial synthesis, catalysis, and therapeutics. Inspired by the programmability and precise three-dimensional architectures of biomolecules, here we demonstrate the strategy of fabricating controlled hierarchical structures through self-assembly of folded synthetic polymers. Linear poly(2-hydroxyethyl methacrylate) of different lengths are folded into cyclic polymers and their self-assembly into hierarchical structures is elucidated by various experimental techniques and molecular dynamics simulations. Based on their structural similarity, macrocyclic brush polymers with amphiphilic block side chains are synthesized, which can self-assemble into wormlike and higher-ordered structures. Our work points out the vital role of polymer folding in macromolecular self-assembly and establishes a versatile approach for constructing biomimetic hierarchical assemblies.


Author(s):  
J. R. Beisheim ◽  
G. B. Sinclair ◽  
P. J. Roache

Current computational capabilities facilitate the application of finite element analysis (FEA) to three-dimensional geometries to determine peak stresses. The three-dimensional stress concentrations so quantified are useful in practice provided the discretization error attending their determination with finite elements has been sufficiently controlled. Here, we provide some convergence checks and companion a posteriori error estimates that can be used to verify such three-dimensional FEA, and thus enable engineers to control discretization errors. These checks are designed to promote conservative error estimation. They are applied to twelve three-dimensional test problems that have exact solutions for their peak stresses. Error levels in the FEA of these peak stresses are classified in accordance with: 1–5%, satisfactory; 1/5–1%, good; and <1/5%, excellent. The present convergence checks result in 111 error assessments for the test problems. For these 111, errors are assessed as being at the same level as true exact errors on 99 occasions, one level worse for the other 12. Hence, stress error estimation that is largely reasonably accurate (89%), and otherwise modestly conservative (11%).


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