scholarly journals Ethnobotanical Survey of Medicinal Plants Used by Traditional Healers to Treat Diabetes in the Taza Region of Morocco

2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Hanae Naceiri Mrabti ◽  
Abdelhakim Bouyahya ◽  
Nidal Naceiri Mrabti ◽  
Nidal Jaradat ◽  
Latifa Doudach ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Herbal Medicines ◽  
Traditional Healers ◽  
Noncommunicable Diseases ◽  
Ethnobotanical Survey ◽  
Healthcare Needs ◽  
Treatment Of Diabetes

Type 2 diabetes is one of the noncommunicable diseases that is becoming a pandemic in Africa. In Morocco, traditional healers have started to use herbal medicines for the treatment of diabetes either individually or in combination with food. The current study aimed to perform an ethnobiological survey of antidiabetic plants use in the Taza region of Morocco. A total of 193 traditional healers were interviewed using a semistructured questionnaire. Data collected were analyzed utilizing the use value (UV), fidelity level (FL), and relative frequency citation (RFC) indices. Forty-six plant species belonging to 28 families were recorded for the treatment of diabetes in the Taza region of Morocco. The most frequently cited plant species are Salvia officinalis, Marrubium vulgare, and Ajuga iva. Lamiaceae, Asteraceae, and Fabaceae were the most reported families. Leaves are the most used part of plants to prepare drugs, the decoction is the preferred mode of preparation, and remedies are often administered orally. Interestingly, Cytisus battandieri, Urginea maritima, Plantago ovata, and Ziziphus jujuba were reported as new medicinal plants used to treat diabetes in the Taza region of Morocco. People in the Taza region still rely on indigenous plants for their basic healthcare needs. Further research should be carried out to validate the antidiabetic effect of the newly reported plant species. This validation can be investigated by the determination of bioactive compounds and evaluation of their in vitro and in vivo antidiabetic effects.

scholarly journals Medicinal Plants Used as Antitumor Agents in Brazil: An Ethnobotanical Approach

2011 ◽  
Vol 2011 ◽  
pp. 1-14 ◽  
Author(s):  
Joabe Gomes de Melo ◽  
Ariane Gaspar Santos ◽  
Elba Lúcia Cavalcanti de Amorim ◽  
Silene Carneiro do Nascimento ◽  
Ulysses Paulino de Albuquerque
Keyword(s):  
Rural Communities ◽  
Medicinal Plants ◽  
Plant Species ◽  
Urban Areas ◽  
Antitumor Agents ◽  
Pharmacological Study ◽  
Aloe Vera ◽  
Traditional Healers

In this study, we describe the medicinal plants that have been reported to be antitumor agents and that have been used in ethnobotanic research in Brazil to answer the following questions: what is the abundance of plants reported to be antitumor in Brazil? Have the plant species used for tumor treatment in traditional Brazilian medicine been sufficiently examined scientifically? Our analysis included papers published between 1980 and 2008. A total of 84 medicinal plant species were reported to be used for cancer and tumor prevention or treatment; 69.05% of these were cited as being used for the treatment of tumors and cancer in general and 30.95% for specific tumors or cancers. The plants that were cited at a higher frequency wereAloe vera,Euphorbia tirucalli, andTabebuia impetiginosa. At least, one pharmacological study was found for 35.71% of the species. Majority of the studies selected were conducted in rural communities and urban areas and in areas with traditional healers in Brazil. We found the following molecules to be the most studied in vitro and in vivo: silibinin, β-lapachone, plumbagin and capsaicin. The species addressed here constitute interesting objects for future studies to various professionals in the field of natural products.

scholarly journals A Review of Plants Used in South African Traditional Medicine for the Management and Treatment of Hypertension

Planta Medica ◽  
2018 ◽  
Vol 85 (04) ◽  
pp. 312-334 ◽  
Author(s):  
Fatai Balogun ◽  
Anofi Ashafa
Keyword(s):  
South Africa ◽  
Medicinal Plants ◽  
South African ◽  
Plant Species ◽  
Agricultural Research ◽  
Higher Plants ◽  
In Vivo Studies ◽  
Research Councils

AbstractSouth Africa contains 9% of the worldʼs higher plants, and despite its rich biodiversity, it has one of the highest prevalence of hypertension in Africa. This review provides information on medicinal plants embraced in South Africa for hypertension management, with the aim of reporting pharmacological information on the indigenous use of these plants as antihypertensives. This review not only focuses on the activity of antihypertensive medicinal plants but also reports some of its phytochemical constituents and other ethnopharmacological and therapeutic properties. Information obtained from scientific and or unpublished databases such as Science Direct, PubMed, SciFinder, JSTOR, Google Scholar, Web of Science, and various books revealed 117 documented antihypertensive plant species from 50 families. Interestingly, Asteraceae topped the list with 16 species, followed by Fabaceae with 8 species; however, only 25% of all plant species have demonstrated antihypertensive effects originating from both in vitro and in vivo studies, lending credence to their folkloric use. Only 11 plant species reportedly possess antihypertensive properties in animal models, with very few species subjected to analytical processes to reveal the identity of their bioactive antihypertensive compounds. In this review, we hope to encourage researchers and global research institutions (universities, agricultural research councils, and medical research councils), particularly those showing an interest in natural products, for the need for concerted efforts to undertake more studies aimed at revealing the untapped potential of these plants. These studies are very important for the development of new pharmaceuticals of natural origin useful for the management of hypertension.

scholarly journals Medicinal Plants Used for the Traditional Management of Diabetes in the Eastern Cape, South Africa: Pharmacology and Toxicology

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2759 ◽  
Author(s):  
Samuel Odeyemi ◽  
Graeme Bradley
Keyword(s):  
South Africa ◽  
Medicinal Plants ◽  
Scientific Evidence ◽  
Traditional Healers ◽  
Bioactive Molecules ◽  
Eastern Cape ◽  
Insulin Mimetic ◽  
Almost All

The use of medicinal plants for the management of diabetes mellitus is on the rise in the developing countries, including South Africa. There is increasing scientific evidence that supports the claims by the traditional healers. In this review, we compare the families of previously reported anti-diabetic plants in the Eastern Cape by rating the anti-diabetic activity, mode of action and also highlight their therapeutic potentials based on the available evidence on their pharmacology and toxicity. Forty-five plants mentioned in ethnobotanical surveys were subjected to a comprehensive literature search in the available electronic databases such as PubMed, ScienceDirect, Google Scholar and Elsevier, by using “plant name” and “family” as the keywords for the primary searches to determine the plants that have been scientifically investigated for anti-diabetic activity. The search returned 25 families with Asteraceae highly reported, followed by Asphodelaceae and Alliaceae. Most of the plants have been studied for their anti-diabetic potentials in vivo and/or in vitro, with most of the plants having a higher percentage of insulin release and inhibition against carbohydrate digesting enzymes as compared with insulin mimetic and peripheral glucose uptake. Almost all the investigated plants also inhibit oxidative stress as part of their hypoglycemic activity with less toxicity. However, the isolation of their bioactive molecules is still lacking. This review provides a resource to enable thorough assessments of the therapeutic profiles of available medicinal plants used for the management of diabetes in the Eastern Cape, South Africa. Further studies such as the identification of the active ingredients of potent plants still need to be carried out; this may lead to new molecules in drug discovery and development.

scholarly journals Antiplasmodial, antimalarial activities and toxicity of African medicinal plants: a systematic review of literature

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Elahe Tajbakhsh ◽  
Tebit Emmanuel Kwenti ◽  
Parya Kheyri ◽  
Saeed Nezaratizade ◽  
David S. Lindsay ◽  
...  
Keyword(s):  
Systematic Review ◽  
Medicinal Plants ◽  
Plant Species ◽  
Azadirachta Indica ◽  
Antiplasmodial Activity ◽  
Research Articles ◽  
Moderate Activity ◽  
Maytenus Senegalensis

Abstract Background Malaria still constitutes a major public health menace, especially in tropical and subtropical countries. Close to half a million people mainly children in Africa, die every year from the disease. With the rising resistance to frontline drugs (artemisinin-based combinations), there is a need to accelerate the discovery and development of newer anti-malarial drugs. A systematic review was conducted to identify the African medicinal plants with significant antiplasmodial and/or anti-malarial activity, toxicity, as wells as assessing the variation in their activity between study designs (in vitro and in vivo). Methods Key health-related databases including Google Scholar, PubMed, PubMed Central, and Science Direct were searched for relevant literature on the antiplasmodial and anti-malarial activities of African medicinal plants. Results In total, 200 research articles were identified, a majority of which were studies conducted in Nigeria. The selected research articles constituted 722 independent experiments evaluating 502 plant species. Of the 722 studies, 81.9%, 12.4%, and 5.5% were in vitro, in vivo, and combined in vitro and in vivo, respectively. The most frequently investigated plant species were Azadirachta indica, Zanthoxylum chalybeum, Picrilima nitida, and Nauclea latifolia meanwhile Fabaceae, Euphorbiaceae, Annonaceae, Rubiaceae, Rutaceae, Meliaceae, and Lamiaceae were the most frequently investigated plant families. Overall, 248 (34.3%), 241 (33.4%), and 233 (32.3%) of the studies reported very good, good, and moderate activity, respectively. Alchornea cordifolia, Flueggea virosa, Cryptolepis sanguinolenta, Zanthoxylum chalybeum, and Maytenus senegalensis gave consistently very good activity across the different studies. In all, only 31 (4.3%) of studies involved pure compounds and these had significantly (p = 0.044) higher antiplasmodial activity relative to crude extracts. Out of the 198 plant species tested for toxicity, 52 (26.3%) demonstrated some degree of toxicity, with toxicity most frequently reported with Azadirachta indica and Vernonia amygdalina. These species were equally the most frequently inactive plants reported. The leaves were the most frequently reported toxic part of plants used. Furthermore, toxicity was observed to decrease with increasing antiplasmodial activity. Conclusions Although there are many indigenous plants with considerable antiplasmodial and anti-malarial activity, the progress in the development of new anti-malarial drugs from African medicinal plants is still slothful, with only one clinical trial with Cochlospermum planchonii (Bixaceae) conducted to date. There is, therefore, the need to scale up anti-malarial drug discovery in the African region.

scholarly journals An ethnobotanical survey of medicinal plants used by traditional healers for the treatment of cancer in Hammanskraal and Winterveld, Tshwane Metropolitan Municipality, South Africa

2021 ◽  
Vol 21 (4) ◽  
pp. 1746-53
Author(s):  
Idris O Raimi ◽  
Boikanyo G Kopaopa ◽  
Liziwe L Mugivhisa ◽  
Francis B Lewu ◽  
Stephen O Amoo ◽  
...  
Keyword(s):  
South Africa ◽  
Skin Cancer ◽  
Medicinal Plants ◽  
Plant Species ◽  
Trifolium Pratense ◽  
Traditional Healers ◽  
Ethnobotanical Survey ◽  
Indigenous Plants ◽  
Citation Frequency ◽  
Traditional Practitioners

Background: Knowledge of medicinal plants used by the traditional healers are mostly confined among the locals and the adherents, hence, proper enquiry and documentation can help the ever dynamic scientific world to find permanent cure to the menace of such deadly diseases such as cancer. This study aimed at (1) specifically recording medicinal plants traditionally used for the treatment of cancer in Hammanskraal and Winterveld, South Africa, and (2) documenting the different methods of preparation and administration of those medicinal plants as recorded during the study. Method: An open-ended semi-structured questionnaire was administered to 90 willing traditional healers in Hammanskraal and Winterveld area, Tshwane Municipality, South Africa to document plants used for cancer treatments. The study was conducted over a period of six months (July – December, 2018). Descriptive statistics was used to present the obtained data. Results: The study recorded twenty-eight plant species belonging to 18 families for the treatment of different types of cancer. Plant species in the Fabaceae family particularly Lessertia frutescens (L.) Goldblatt and J.C. Manning, Senna italica Mill and Trifolium pratense L. were the most prominently mentioned (highest citation frequency) by the traditional healers for lung, and skin cancer treatment. Based on the citation frequency, the most treated cancer by the traditional healers is in the order: skin cancer > lung cancer > breast cancer > prostate cancer > cervical cancer. The method of preparation included decoction(32.3%), infusion (29%), paste (16.1%) and maceration (22.6%). Conclusion: In addition to the documentation of indigenous knowledge related to the use of medicinal plants in the traditional management of cancer in South Africa, this study opens a vista for investigations into the phytochemical and pharmacological properties of the documented plants. Keywords: Cancer; Indigenous plants; Medicinal plants; South Africa; Traditional practitioners.

scholarly journals Documentation of Indigenous Knowledge on Folk Medicine in Doddakavalande Doddakavalande Hobli, Nanjangud Taluk of Mysore District, Karnataka

2020 ◽  
Vol 10 (1) ◽  
pp. 39-47
Author(s):  
M Nagalakshmi ◽  
S Rashmi
Keyword(s):  
Medicinal Plants ◽  
Indigenous Knowledge ◽  
Traditional Knowledge ◽  
Plant Species ◽  
Folk Medicine ◽  
Traditional Healers ◽  
Drug Formulation ◽  
Ethnobotanical Survey ◽  
Traditional Medicines ◽  
Herbal Formulations

An ethnobotanical survey was conducted to collect information from traditional healers on the use of herbal medicine in Doddakavalande Hobli, Nanjangud taluk of Mysore District. The indigenous knowledge of local healers was documented through questionnaire and personal interviews. In the present study, about 19 respondents of age group between 50 to 89 yrs gave information of traditional medicines used to cure different ailments. Of about 35 plant species belonging to 26 families were used for the treatment of human ailments. In which family Fabaceae and Polygonaceae contained 3 plant species, followed by Acanthaceae, Amaranthaceae, Apocynaceae, Cucurbitaceae, Poaceae contained 2 species each, and the rest of the families Amaryllidaceae, Anacardiaceae, Apiaceae, Aristolochiaceae, Asteraceae, Cleastraceae, Crassulaceae, Lamiaceae, Lecythidaceae,  Meliaceae,  Olaceae, Phylanthaceae, Piperaceae,  Plumbaginaceae, Poaceae, Polygonaceae, Rutaceae,  Smilacaceae, Solanaceae,  Styracaceae and Zingiberaceae. Habit wise analysis of medicinal plant species used indicated that herbs (19 species) were the most preferred life form followed by trees (8 species), shrubs (5 species) and climbers (3 species) for drug formulation. Herbal formulations were administrated either internally or applied externally depending on the type of ailment. Local people in the study area possess traditional knowledge of medicinal plants to treat various human ailments, therefore it is necessary to preserve the indigenous knowledge on traditional medicines by proper documentation, identification of plant species used, and herbal preparation. Keywords: Ethnobotany, Traditional knowledge, Medicinal plants, Mysore district.

scholarly journals Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases

2021 ◽  
Vol 22 (22) ◽  
pp. 12255
Author(s):  
Niti Sharma ◽  
Mario A. Tan ◽  
Seong Soo A. An
Keyword(s):  
Natural Products ◽  
Neurodegenerative Diseases ◽  
Plant Species ◽  
Biological Activities ◽  
Herbal Medicines ◽  
Pharmacological Activities ◽  
Isolated Structures ◽  
Biological And Pharmacological Activities

Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 200 types of phytosterols, stigmasterol and β-sitosterol were ubiquitous in many plant species, exhibiting important aspects of activities related to neurodegenerative diseases. Hence, this mini-review presented an overview of the reported studies on selected phytosterols related to neurodegenerative diseases. It covered the major phytosterols based on biosynthetic considerations, including other phytosterols with significant in vitro and in vivo biological activities.

scholarly journals Ethnomedicinal Study of Plants in Begumgonj, Noakhali, Bangladesh

2021 ◽  
Author(s):  
Akter Kazi-Marjahan ◽  
Noor Hasan Sajib ◽  
Dong-Min Kang ◽  
Mi-Jeong Ahn ◽  
Sheik Bokhtear Uddin
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Skin Diseases ◽  
Traditional Healers ◽  
Ethnobotanical Survey ◽  
Traditional Use ◽  
Informant Consensus ◽  
Field Interview ◽  
Ethnomedicinal Knowledge ◽  
Area Data

Abstract Backgraound: The aim of this study was to document and preserve the ethnomedicinal knowledge used by traditional healers of Begumganj upazila, Bangladesh, to treat human diseases and evaluate the relative efficacy of the medicinal plants.Methods: The uses of medicinal plants were documented as an ethnomedicinal data sheet using direct observation, field interview, plant interview and group interview techniques from December 2012 to January 2014 in the study area. Data were collected from 98 traditional healers through a questionnaire survey and analyzed through informant consensus factor and fidelity level.Results: Overall, 75 plant species under 71 genera of 47 families were documented, which are used to treat 41 diseases. Data analysis revealed that 41.33%, 14.67%, 36% and 8% of the medicinal plant species were herbs, shrubs, trees, and climbers, respectively. Leaves were the most used parts, followed by stem, root, fruit, bark, latex and rhizome. The most frequently treated diseases were dysentery, rheumatism and skin diseases.Conclusions: This is the first ethnobotanical survey, which recorded the importance of medicinal plants in Begumgonj upazila, Bangladesh. This study can contribute to preserving the indigenous knowledge on the traditional use of medicinal plants in this region and attract future generations towards traditional healing practice.

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