Paediatric High-Grade Intracranial Mesenchymal Chondrosarcoma: A Case Report with 6 Years of Follow-Up without Recurrence

2020 ◽  
Vol 55 (5) ◽  
pp. 299-303
Author(s):  
Kemal Alper Afşer ◽  
İsmail İştemen ◽  
Ali Arslan ◽  
Ali Ihsan Ökten
Keyword(s):  
Adjuvant Radiotherapy ◽  
Young Male ◽  
Malignant Tumour ◽  
Mesenchymal Chondrosarcoma ◽  
Radical Excision ◽  
Rare Tumour ◽  
Case Presentation ◽  
Central Nervous System Tumours ◽  
Poorly Differentiated

<b><i>Introduction:</i></b> Intracranial mesenchymal chondrosarcoma (MSC) is an extremely rare tumour that constitutes only 0.015% of all central nervous system tumours. These tumours usually originate from skull base synchondrosis and are often observed in young adults during their second and third decades of life. Despite the absence of a consensus regarding adjuvant radiotherapy, radical excision remains crucial for the prognosis of MSC. <b><i>Case Presentation:</i></b> We herein present the case of a young male patient with intracranial MSC, a malignant tumour, for which no consensus regarding its treatment has yet been established. The patient underwent radical excision followed by adjuvant radiotherapy. Histological analysis revealed a poorly differentiated tumour containing necrotic areas. Notably, no signs of recurrence had been observed after 6 years. <b><i>Conclusion:</i></b> The absence of recurrence over a long follow-up duration suggests the importance of radical excision and adjuvant radiotherapy.

scholarly journals Mesenchymal chondrosarcoma of maxilla in paediatric patient

2019 ◽  
Vol 12 (3) ◽  
pp. e228969 ◽  
Author(s):  
Choon Sean Choo ◽  
Wan Faiziah Wan Abdul Rahman ◽  
Hasnan Jaafar ◽  
Ramiza Ramza Ramli
Keyword(s):  
Hyaline Cartilage ◽  
Malignant Tumour ◽  
Mesenchymal Chondrosarcoma ◽  
Tumour Metastasis ◽  
Radiologic Findings ◽  
Flat Bone ◽  
Erroneous Diagnosis ◽  
Extensive Lesion ◽  
Well Differentiated

Chondrosarcoma (CS) is a malignant tumour of long and flat bone characterised by the formation of cartilage. Mesenchymal chondrosarcoma (MCS) is a rare subtype of CS that is more aggressive and may lead to erroneous diagnosis in a limited biopsy. The diagnosis is mainly based on the histopathological appearance of biphasic pattern of undifferentiated small round cells separated by islands of well-differentiated hyaline cartilage. We report a case of 13-year-old boy who initially presented with gum swelling and the biopsy result suggested a benign fibrous lesion. Following an extensive lesion shown in radiologic findings, the tumour excision was done and finally was diagnosed as an MCS of the maxilla. The patient was given postoperative chemotherapy (EURO-EWING 99 regimen), and now on regular follow-up for monitoring of local recurrence or tumour metastasis.

scholarly journals Primary orbital extraskeletal osteosarcoma and review of literature

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jingwen Hui ◽  
Yun Zhao ◽  
Lei Zhang ◽  
Jinyong Lin ◽  
Hong Zhao
Keyword(s):  
Soft Tissues ◽  
Malignant Tumour ◽  
Extraskeletal Osteosarcoma ◽  
Complete Excision ◽  
Case Presentation ◽  
Left Orbit ◽  
Orbital Wall ◽  
Previous Trauma ◽  
History Of

Abstract Background Extraskeletal osteosarcoma is a malignant tumour composed of an osteoid and/or cartilaginous matrix; it arises in soft tissues without connection to the skeleton, and to our knowledge, this type of tumour is extremely rare. Case presentation The present study reports a 57-year-old man with primary orbital extraskeletal osteosarcoma who presented with a history of painful swelling in the left orbit that had occurred for 11 months. Imaging of the orbit showed an atypical, well-defined heterogeneous mass attached to the posterior globe of the left orbit. The patient underwent an anterior orbitotomy and complete excision of the tumour. The mass was originated from neither the globe nor the bony orbital wall but from the soft tissue. Histopathology demonstrated an extraskeletal osteosarcoma. After 13 months of follow-up, there was apparent recurrence of the tumour. The medical history showed no complaints of previous trauma or radiotherapy. Conclusions ESOS is a highly malignant tumour. Immunosuppression, trauma and adjuvant radiotherapy are possible predisposing factors in the development of this tumour. Prompt recognition and thorough treatment are essential for preventing orbital lesions and presence of metastasis from other organs.

scholarly journals Scalp Metastasis of Cervical Cancer With Favorable Outcome

2020 ◽  
Vol 8 (3) ◽  
pp. 333-335
Author(s):  
Elham Saffarieh ◽  
Setare Nassiri ◽  
Maedeh Brahman ◽  
Soheila Amini Moghaddam ◽  
Shima Hosseini
Keyword(s):  
Cervical Cancer ◽  
Multidisciplinary Approach ◽  
Uterine Cervical Cancer ◽  
Radical Excision ◽  
Hematogenous Spread ◽  
Papilloma Virus ◽  
Case Presentation ◽  
Frontal Part ◽  
Scalp Metastasis

Introduction: Carcinoma of the uterine cervix is the most common gynecological malignancies in developing countries. Human papilloma virus is known as the main etiology. In addition, the spread of uterine cervical cancer often occurs through direct local extension and the lymphatics although the hematogenous spread is uncommon. Further, the scalp metastasis of cervical cancer is extremely rare. Case Presentation: In this regard, a 50-year-old woman with scalp metastasis of previous cervical cancer was discussed in the present study. She was suffering from a fast-growing and painful nodule, located on the frontal part of the scalp as a sole site of metastasis. A multidisciplinary approach was considered for her, which consisted of radical excision, followed by radiotherapy and chemotherapy. Given the lack of abundant evidence for the efficacy of this treatment, our patient has fortunately survived for more than two years. Conclusions: During the follow-up period after the completion of treatment, it is not sensible to only focus on the primary site of the tumor and thus entire examination is mandatory in this regard.

scholarly journals Dermatofibrosarcoma Protuberans: A Rare Cause of Neck Swelling

2020 ◽  
Vol 22 (2) ◽  
pp. 110-113
Author(s):  
Md Abdur Rahman ◽  
Mahbubul Alam ◽  
ABM Luthful Kabir ◽  
Mohammod Harun Or Rarhid ◽  
Abul Kalam Prodhan
Keyword(s):  
Adjuvant Radiotherapy ◽  
Cutaneous Lesion ◽  
Dermatofibrosarcoma Protuberans ◽  
Complete Removal ◽  
Low Grade ◽  
Incisional Biopsy ◽  
Neck Swelling ◽  
Rare Tumour ◽  
History Of

Dermatofibrosarcomaprotuberans (DFSP) is a low-grade soft tissue sarcoma (fibrosarcoma) originated from dermal and subdermal layer of the skin. The tumor infiltrates into the deeps in the form of villous or finger. For this reason, it is quite difficult to get clear surgical margins during tumor excision and the recurrence is a problem encountered frequently. We are reporting this rare tumour in a 40-year-old man presented with a 5-years history of slowly growing cutaneous lesion of the neck. Incisional biopsy confirmed the diagnosis of DFSP. Subsequently, the patient underwent wide local surgical resection, followed by reconstruction. Histopathology report revealed dermatofibrosarcomaprotuberans (DFSP). Although DFSP behave as non-aggressive malignancy, surgery with complete removal of the affected area is the treatment of choice. Moreover, adjuvant radiotherapy and follow-up of the patient is essential in order to prevent recurrence. Bangladesh J Otorhinolaryngol; October 2016; 22(2): 110-113

scholarly journals Resection of a Rare Metacarpal Distal Condyle Osteoid Osteoma

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Bachar El Fatayri ◽  
Az-Eddine Djebara ◽  
Alex Fourdrain ◽  
Yassine Bulaid ◽  
Mario Sanguina
Keyword(s):  
Osteoid Osteoma ◽  
Young Male ◽  
Joint Space ◽  
Metacarpal Bone ◽  
Common Symptom ◽  
Case Presentation ◽  
Left Hand ◽  
Rare Location ◽  
Inflammatory Drugs

Introduction. Osteoid osteoma is a benign bone-forming tumor with young male predilection. It occurs predominantly in the long bones. In the hand, osteoid osteoma is more commonly located in the phalanges and carpal bones. The metacarpals are the least common site for osteoid osteoma. Pain is the most common symptom. It usually increases at night and responds to nonsteroidal anti-inflammatory drugs. Case Presentation. The authors report the excision of an osteoid osteoma lying at the distal condyle of a metacarpal bone of the left hand. The clinical and radiological findings are exposed as well as the surgical management of the lesion. Pain and swelling disappeared after surgery, and there was no evidence of recurrence at follow-up. Discussion. They discuss this rare location and further radiological examination that was used leading to the diagnosis. The imputation of the traumatic factor has been discussed, along with the different therapeutic possibilities and the advantages of a total excision while preserving the integrity of the adjacent ligament and joint space. Conclusion. The surgical alternative appears to be a satisfying treatment for osteoid osteoma in this particular superficial location. Both the exact pathogenesis and the contribution of the traumatic factor remain unclear.

scholarly journals Recurrent sinonasal teratocarcinosarcoma treated with IMRT: a case report

2019 ◽  
Vol 5 (4) ◽  
pp. 1126
Author(s):  
Rajanigandha Tudu ◽  
Anup Kumar ◽  
Rashmi Singh ◽  
Payal Raina ◽  
Praveer Kumar Singh Munda
Keyword(s):  
Malignant Tumour ◽  
Undifferentiated Carcinoma ◽  
Adjuvant Radiation ◽  
Adjuvant Chemoradiation ◽  
Neck Node ◽  
Definitive Radiotherapy ◽  
Bony Destruction ◽  
Poorly Differentiated ◽  
Sinonasal Teratocarcinosarcoma

<p class="abstract">Sinonasal teratocarcinosarcoma is a rare malignant tumour displaying aggressive growth .It is known to have poor prognosis with locoregional recurrence. So far, the most widely accepted therapeutic plan for its management has been surgery followed by adjuvant radiation. This study reports a case of 35 year old male diagnosed with sinonasal undifferentiated carcinoma who presented with neck node recurrence after 15 months of definitive radiotherapy. A 35 year old patient presented with nasal obstruction and epistaxis. CECT PNS revealed mass in ethmoid sinus with adjacent bony destruction and infiltration into maxillary sinus and nasal cavity. Biopsy revealed poorly differentiated carcinoma. Patient underwent neoadjuvant chemotherapy followed by definitive radiotherapy by IMRT. On follow up at 15 months, the patient presented with nodal recurrence. Biopsy from neck node revealed metastatic sinonasal teratocarcinosarcoma. The patient underwent neck dissection followed by adjuvant chemoradiation. The patient is currently on follow up and is disease free till date. Surgery alongwith adjuvant chemoradiation is a reasonable therapeutic approach of management for sinonasal teratocarcinosarcoma.</p><p class="abstract"> </p>

scholarly journals An Unusual Dermoid Cyst of the Pineal Region. Case report in a Child

2020 ◽  
Author(s):  
Mohammad Jamali ◽  
Iman Ahrari ◽  
Arash Saffarrian ◽  
Keyvan Eghbal ◽  
Abbas Rakhsha ◽  
...  
Keyword(s):  
Dermoid Cyst ◽  
Pineal Region ◽  
Endoscopic Biopsy ◽  
Radical Excision ◽  
Case Presentation ◽  
Common Location ◽  
Adjacent Structures ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain

Abstract Introduction The pineal gland is a common location for intracranial germ cells, but dermoids are not commonly observed in this area. In the present paper, we discuss the clinical and radiological features as well as the treatment and outcome of this cyst in a 6-year- old child with a pineal dermoid cyst. Case Presentation The patient presented with chronic headache 6 months before admission in 2018. On the first admission, an enhanced lesion with a small cyst was detected in brain imaging. Magnetic resonance imaging (MRI) of the brain at follow-up (2 months after the first presentation) showed enlargement of the cyst size with compression on the adjacent structures. Radical excision of the tumor was performed after the endoscopic biopsy due to pressure exerted on the adjacent structures. Conclusion Dermoid cyst should be considered as a differential diagnosis for enhanced lesions of the pineal region.

scholarly journals Diagnosis and analysis of a sebaceous gland tumour of the external acoustic meatus in a Cocker Spaniel dog

2021 ◽  
Vol 90 (1) ◽  
pp. 87-89
Author(s):  
Jiashi Dong ◽  
Chunling Fan ◽  
Dingxin Liu ◽  
Peng Li
Keyword(s):  
Incidence Rate ◽  
Sebaceous Gland ◽  
External Auditory Meatus ◽  
Malignant Tumour ◽  
Whole Body ◽  
Rare Tumour ◽  
Low Incidence ◽  
One Year ◽  
Gland Tumour

Sebaceous gland tumour (SGT) is a rare tumour with a low incidence rate, which mainly occurs in the eyelid and periocular sebaceous gland. In 2019, our laboratory received a case involving a sebaceous gland tumour of the external auditory meatus for pathological diagnosis. It is a rare malignant tumour in the whole body. Data regarding a sebaceous gland tumour in the dogís external auditory meatus are few. This case is instructive for veterinary diagnosis and treatment. The dog recovered well after surgery at the outpatient department, and no recurrence was observed in the follow-up visit one year later. This study will help the identification of SGT in Spaniel dogs.

Primary Calvarial Ewing Sarcoma: A Case Series

2021 ◽  
Author(s):  
Sandeep Mohindra ◽  
Manjul Tripathi ◽  
Aman Batish ◽  
Ankur Kapoor ◽  
Ninad Ramesh Patil ◽  
...  
Keyword(s):  
Ewing Sarcoma ◽  
Tumor Resection ◽  
Case Series ◽  
Radical Excision ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Intradural Tumor ◽  
Age Range

Abstract Background Calvarial Ewing tumor is a relatively rare differential among bony neoplasms. We present our experience of managing primary calvarial Ewing sarcoma (EWS), highlighting their clinical and radiological findings. Method In a retrospective analysis, we evaluated our 12-year database for pathologically proven EWS. A literature search was conducted for the comparative presentation and update on the management and outcome. Result From January 2008 to December 2020, we managed eight patients (male:female = 5:3; age range 6 months to 19 years, mean 11.5 years) harboring primary calvarial EWS. All cases underwent wide local excision; two patients required intradural tumor resection, while one required rotation flap for scalp reconstruction. Mean hospital stay was 8 days. All patients received adjuvant chemo- and radiotherapy. Three patients remained asymptomatic at 5 years of follow-up, while two patients died. Conclusion Primary calvarial EWS is a rare entity. It usually affects patients in the first two decades of life. These tumors can be purely intracranial, causing raised intracranial pressure symptoms, which may exhibit rapidly enlarging subgaleal tumors with only cosmetic deformities or symptoms of both. Radical excision followed by adjuvant therapy may offer a favorable long-term outcome.

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