Abstract 3388: Awareness and Risk for Stroke among Community Living Middle-Aged Adults in Korea

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Kyoung Nam ◽  
Hee-Young Song

Background Control of stroke risk factors, in particular, hypertension and unhealthy life styles such as high fat diet, and inactivity which are modifiable have been focused for primary prevention of stroke. Greater awareness for stroke may promote individual to involve preventive activities. In Korea, relatively little research has been done on the awareness and risk for stroke among community living adults. We investigated awareness for stroke, calculated stroke risk score using the Framingham stroke risk score profile, and examined the relationship among awareness for stroke, blood pressure(BP), body weight, blood sugar, cholesterol and stroke risk score among middle-aged adults in Korea. Methods A total of 99 participants ( 3 9 men, 60 women) aged 47.0 years old were recruited in an urban area and were interviewed by researchers using a structured questionnaire including stroke risk factors. Awareness for stroke was assessed with baseline knowledge on stroke risk factors, symptoms, and treatment; and recognition on important indicators such as BP, body weight, blood sugar and cholesterol. Stroke risk was determined by applying the Framingham stroke risk profile. Data were analyzed by descriptive statistics, t-test, and Pearson’s correlation using PASW statistics 18.0. Results Participants answered more than 3 stroke warning signs out of 5, although most participants did not know if their BP, body weight, blood sugar, and cholesterol were within normal limits. Scores of stroke risk determined by Framingham stroke risk profile showed significant difference between men and women (3.85±2.35 vs. 2.52±.06) (t=2.968, p=.004). Only systolic blood pressure was related with stroke risk in men(r=.537, p=.002), while blood sugar(r=.497, p=.005), systolic(r=.705, p <.001) and diastolic blood pressure(r=.557, p<.001) were related with stroke risk in women. The negative correlation between awareness for stroke and stroke risk was found in women(r=-.303, p=.021). Conclusions There is need to improve the awareness of stroke among community living middle-aged adults by providing more targeted information on stroke risk factors and their contribution to stroke prevention.Further studies are warranted to refine predictive factors for the risk of stroke, regarding gender difference in relationship between stroke risk score and BP, body weight, blood sugar and cholesterol which are important indicators for major illness related to stroke.

2017 ◽  
Vol 117 (4) ◽  
pp. 582-590 ◽  
Author(s):  
Roya Daneshmand ◽  
Sudhir Kurl ◽  
Tomi-Pekka Tuomainen ◽  
Jyrki K. Virtanen

AbstractStroke is a leading cause of morbidity and mortality. The role of PUFA in reducing the risk of stroke is uncertain. The concentrations of PUFA in the human body are determined both by dietary intake and by activities of desaturase enzymes. Desaturase enzymes have been associated with chronic diseases, but little is known about their association with stroke risk. We investigated the associations of Δ-6-desaturase (D6D) and Δ-5-desaturase (D5D) activities with stroke risk factors and risk of stroke among 1842 men from the prospective, population-based Kuopio Ischaemic Heart Disease Risk Factor Study, aged 42–60 years and free of CVD at baseline in 1984–1989. ANCOVA and Cox regression models were used for the analyses. Whole serum desaturase activities were estimated as product:precursor ratios – γ-linolenic acid:linoleic acid for D6D and arachidonic acid:dihomo-γ-linolenic acid for D5D. Higher D6D activity was associated with higher systolic and diastolic blood pressure, BMI, serum insulin and TAG concentrations and worse homoeostatic model assessment (HOMA) indices. In contrast, higher D5D activity was associated with lower systolic and diastolic blood pressure, BMI, serum insulin, LDL-cholesterol, TAG and C-reactive protein concentrations, higher HDL-cholesterol concentration, and better HOMA indices. During the mean follow-up of 21·2 years, 202 stroke cases occurred. Neither D6D activity (multivariable-adjusted extreme-quartile hazard ratios (HR) 1·18; 95 % CI 0·80, 1·74) nor D5D activity (HR 1·06; 95 % CI 0·70, 1·60) were associated with stroke risk. In conclusion, higher D5D activity was favourably associated and higher D6D activity unfavourably associated with several stroke risk factors, but not with the risk of incident stroke.


2020 ◽  
Vol 43 (1) ◽  
pp. 63-68
Author(s):  
Rodrigo Ferrari ◽  
Eduardo Lusa Cadore ◽  
Bibiana Périco ◽  
Gabriela Bartholomay Kothe

2021 ◽  
Author(s):  
Yèssito Corine Nadège Houehanou ◽  
Mendinatou Agbetou ◽  
Oyéné Kossi ◽  
Maurice Agonnoudé ◽  
Hospice Hountada ◽  
...  

Abstract Background: Sub-Saharan Africa faces a high burden of stroke due to growing of their risk factors. We aimed to estimate the prevalence of stroke risk factors and to identify associated factors in the district of Titirou in Parakou (northern Benin), in 2016.Methods: It was a cross-sectional study. It included adults living in Titirou and having given their consent. A door-to-door survey was performed from 15 march to 15 July 2016 in each neighbourhood or village until the expected number reached. We recorded the socio-demographic data, medical histories, anthropometric and blood pressure measures using WHO steps approach. Prevalences of stroke risk factors were calculated and a logistic regression was done to identify factors associated with metabolic risk factors.Results: A total of 4671 participants was included with a mean age of 27.7±12.9 years and a sex ratio of 0.97. Prevalences of behavioural risk factors were estimated at: 17.2% of alcohol consumption, 21.5% of low fruits and vegetables consumption, 51.1% of low physical activity practice, and 3.5% of smoking. Metabolic risk factors prevalence’s amounted to: 8.7% of obesity, 7.1% of high blood pressure, 1.7% of self-reported diabetes and 2.2% of dyslipidaemia. Age (p<0.001), sex (p<0.001), marital status (p<0.001) and professional occupation (p=0.010) were associated with obesity. Age was also associated with high blood pressure (p<0.001) and diabetes (p<0.001). Dyslipidaemia varied according to smoking (p=0.033) and low physical activity practice (p=0.003). Conclusion: The study showed high prevalences of low physical activity practice and obesity. Targeted local interventions focused on these factors should be conducted for primary prevention of stroke in this community, or even beyond in Benin.


Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Li-Jung Liang ◽  
Stefanie D Vassar ◽  
W. T Longstreth ◽  
Sharon S Merkin ◽  
Jose J Escarce ◽  
...  

Background: Fish consumption has been associated with reduced risk of stroke, and residence in low income neighborhoods has been associated with higher risk of stroke, either directly or through biologic risk factors for stroke, such as hypertension, diabetes, and subclinical disease. No studies, however, have examined the relationship between neighborhood characteristics, fish consumption, and stroke risk factors. Methods: We analyzed data from 3907 adults from the Cardiovascular Health Study (CHS), a population-based, longitudinal study of adults ages ≥65 years from 4 US counties. The outcomes were fish consumption (non-fried fish: ≥5 times/wk, 1-4 times/wk, 1-3 times/mo, <1 time/mo; fried fish: ≥1 times/wk, 1-3 times/mo, <1 time/mo) and stroke risk factors (Framingham stroke risk score [FSRS], diabetes, subclinical CVD [sCVD], hypertension). Neighborhood socioeconomic status (NSES) was measured using a composite of 6 census variables. Hierarchical generalized mixed-effects regression models with census-level random-effects were fit to continuous, binary, and ordinal outcomes adjusted for sociodemographic characteristics. Results: In adjusted analyses, residents of the most disadvantaged neighborhoods had lower consumption of non-fried fish (OR=0.55, 95% CI: 0.41-0.74) and higher consumption of fried fish (OR=1.61, 1.28-2.03). Eating non-fried fish was independently associated with a lower stroke risk score, but not with diabetes, hypertension, or sCVD. However, these relationships differed by neighborhood. Among those who consumed non-fried fish 1-4 times/wk, residents of the most disadvantaged neighborhoods had higher odds of diabetes (OR=1.78; p=0.03) and sCVD (OR=1.59; p=0.003), a trend towards higher odds of hypertension (OR=1.33; p=.054), and a higher FSRS (OR=1.09; p=.03). Eating fried fish was not associated with differences in stroke risk factors or FSRS. Conclusions: Residents of disadvantaged neighborhoods consumed less non-fried fish and more fried fish. Even with the same level of non-fried fish consumption, residents of more disadvantaged neighborhoods did not get the same benefit in stroke risk reduction as residents of higher SES neighborhoods.


2019 ◽  
Vol 8 (4) ◽  
pp. 527 ◽  
Author(s):  
Margaret A. Drazba ◽  
Ida Holásková ◽  
Nadine R. Sahyoun ◽  
Melissa Ventura Marra

Rates of adverse cardiovascular events have increased among middle-aged adults. Elevated ceramides have been proposed as a risk factor for cardiovascular events. Diet quality and weight status are inversely associated with several traditional risk factors; however, the relationship to ceramides is less clear. This study aimed to determine associations of adiposity and diet quality with circulating ceramides in middle-aged adults (n = 96). Diet quality was estimated using the Healthy Eating Index 2015 (HEI-2015). Serum ceramide concentrations were determined by liquid chromatography–mass spectrometry. A ceramide risk score was determined based on ceramides C16:0, C18:0, and C24:1 and their ratios to C24:0. Participants who were classified as at ‘moderate risk’ compared to ‘lower-risk’ based on a ceramide risk score had significantly higher body mass index (BMI) values, as well as higher rates of elevated fibrinogen levels, metabolic syndrome, and former smoking status. BMI was positively associated with the ceramide C18:0 (R2 = 0.31, p < 0.0001), the ratio between C18:0/C24:0 ceramides (R2 = 0.30, p < 0.0001), and the ceramide risk score (R2 = 0.11, p < 0.009). Total HEI-2015 scores (R2 = 0.42, p = 0.02), higher intakes of vegetables (R2 = 0.44, p = 0.02) and whole grains (R2 = 0.43, p = 0.03), and lower intakes of saturated fats (R2 = 0.43, p = 0.04) and added sugar (R2 = 0.44, p = 0.01) were associated with lower C22:0 values. These findings suggest that circulating ceramides are more strongly related to adiposity than overall diet quality. Studies are needed to determine if improvements in weight status result in lower ceramides and ceramide risk scores.


2019 ◽  
Vol 38 (1) ◽  
Author(s):  
Takako Shirasawa ◽  
Hirotaka Ochiai ◽  
Takahiko Yoshimoto ◽  
Satsue Nagahama ◽  
Mariko Kobayashi ◽  
...  

Abstract Background Several studies have shown that normal weight central obesity (NWCO) is associated with cardiovascular disease (CVD) risk factors. However, studies conducted in the Japanese population have been very limited. Thus, the relationships between normal weight central obesity, classified using body mass index (BMI), the waist-to-height ratio (WHtR), and CVD risk factors in middle-aged Japanese adults were investigated. Methods The participants were Japanese adults aged 40–64 years who had undergone periodic health examinations in Japan during the period from April 2013 to March 2014. The participants were categorized into the following four groups: normal weight (BMI 18.5–24.9 kg/m2) and no central obesity (WHtR < 0.5) (NW); normal weight and central obesity (WHtR ≥ 0.5) (NWCO); obesity (BMI ≥ 25 kg/m2) and no central obesity (OB); and obesity and central obesity (OBCO). Hypertension was defined as systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, or taking medication for hypertension. Dyslipidemia was defined as LDL-C ≥ 140 mg/dl, HDL-C < 40 mg/dl, triglyceride ≥ 150 mg/dl, or taking medication for dyslipidemia. Diabetes was defined as fasting plasma glucose ≥ 126 mg/dl, random plasma glucose ≥ 200 mg/dl, HbA1c ≥ 6.5%, or receiving medical treatment for diabetes mellitus. A logistic regression model was used to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension, dyslipidemia, and diabetes. Results A total of 117,163 participants (82,487 men and 34,676 women) were analyzed. The prevalence of NWCO was 15.6% in men and 30.2% in women. With reference to NW, the ORs for hypertension (adjusted OR 1.22, 95% CI 1.17–1.27 in men, 1.23, 1.16–1.31 in women), dyslipidemia (1.81, 1.74–1.89 in men, 1.60, 1.52–1.69 in women), and diabetes (1.35, 1.25–1.46 in men, 1.60, 1.35–1.90 in women) were significantly higher in NWCO. Conclusions Normal weight with central obesity was associated with CVD risk factors, such as hypertension, dyslipidemia, and diabetes, compared with normal weight without central obesity, regardless of sex. It is important to focus on normal weight with central obesity for the prevention of CVD in Japanese middle-aged adults.


2018 ◽  
Vol 50 (3) ◽  
pp. 110-119 ◽  
Author(s):  
Jordana Salma ◽  
Kathleen F. Hunter ◽  
Linda Ogilvie ◽  
Norah Keating

Background Arab immigrants have increasing rates of stroke and uncontrolled stroke risk factors coupled with minimal resources for stroke prevention. Purpose This article describes the results of an interpretive descriptive study about Arab immigrant women’s experiences of practicing stroke prevention. We use an intersectionality approach to discuss some of the factors that influenced women’s ability to manage their health. Methods Sixteen middle-aged and older Arab Muslim immigrant women were recruited between 2015 and 2016 from two religious centers in an urban Canadian center. Women were between the ages of 45 and 75 years, were living in the community, and had a combination of stroke risk factors. Semi-structured interviews lasting 2–3 h were conducted in Arabic by the primary bilingual researcher. Data analysis was completed in Arabic, with final themes and exemplars translated to English with the support of a certified translator. Results Study themes include relating life stressors to physical health, pursuing knowledge in the dark, negotiating medication and treatment options, making an effort to eat healthy and be active, and identifying triple ingredients for empowerment. Conclusion Economic status, access to transportation, language fluency, life stressors, and personal coping strategies influenced Arab women’s ability to manage personal health.


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