The Clinical Value of Transvaginal Sonography Combined with Magnetic Resonance Imaging in Diagnosis of Deep Invasive Endometriosis in Pelvic Cavity

2021 ◽  
Vol 11 (2) ◽  
pp. 568-573
Author(s):  
Qingxue Li ◽  
Jingwei Chen ◽  
Jian Yang ◽  
Chloe Sto ◽  
Angel Ray
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Likelihood Ratio ◽  
Predictive Value ◽  
Gold Standard ◽  
Diagnostic Methods ◽  
Transvaginal Sonography ◽  
Pelvic Cavity ◽  
Resonance Imaging ◽  
Combined Detection

Objective: The objective of this study is to analyze the diagnostic value of transvaginal sonography (TVS), magnetic resonance imaging (MRI) and their combination in patients with deep invasive endometriosis (DIE) in pelvic cavity. Method: In this study, 235 patients with DIE were selected as the study objects, and the lesion location of the patients was determined by TVS, MRI, and combined examination before surgery. According to the actual situation of the patient, laparoscopic or open surgery was performed to remove the lesion tissue, which was regarded as the gold standard. The sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio of TVS, MRI, and combined diagnosis were compared. In addition, Kappa test was adopted to compare the consistency between different diagnostic methods and the gold standard. Results: The total Se of the DIE detected by THV was 91.61%, and the Sp was 90.74%. The total Se of DIE detected by MRI was 95.76%, and the Sp was 92.07%. The total Se of DIE detected by THV combined with MRI was 96.47%, and the Sp was 93.41%. The LR– value of DIE detected by TVS was 0.21, the LR– value detected by MRI was 0.18, and the LR– value detected by combined detection was 0.13. The κ coefficient of DIE detected by TVS was 0.70, the κ coefficient detected by MRI was 0.73, and the κ coefficient by combined detection was 0.79. Conclusion: TVS combined with MRI to detect DIE has a higher sensitivity and specificity, a higher positive detection rate, and a higher consistency with the diagnostic results of gold standard.

scholarly journals Correlation of clinical examination, ultrasound, magnetic resonance imaging and arthroscopy as diagnostic tools in shoulder pathology

2020 ◽  
Vol 6 (2) ◽  
pp. 247
Author(s):  
Sondipon Biswas ◽  
Naman Kanodia ◽  
Rajat Tak ◽  
Siddharth Agrawal ◽  
Kiran Shankar Roy
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Rotator Cuff ◽  
Positive Predictive Value ◽  
Negative Predictive Value ◽  
Predictive Value ◽  
Gold Standard ◽  
Shoulder Arthroscopy ◽  
Resonance Imaging ◽  
Shoulder Pathologies

<p class="abstract"><strong>Background:</strong> Shoulder pathologies can cause significant pain, discomfort, and affect the activity of daily living. The aim of this study was to compare the efficacy of clinical examination, ultrasound, magnetic resonance imaging (MRI) with shoulder arthroscopy in diagnosing various shoulder pathologies, considering shoulder arthroscopy as the gold standard tool.</p><p class="abstract"><strong>Methods:</strong> This was a prospective, comparative study conducted over 35 patients, between 18-75 years of age presenting with chronic shoulder pain or instability of more than 2 months duration. All patients were examined clinically, followed by high resolution ultrasound, MRI, arthroscopy of the affected shoulder.<strong></strong></p><p class="abstract"><strong>Results:</strong> The sensitivity and specificity of ultrasonography (USG) for diagnosing full thickness tear was 100% each and for MRI was 88% and 100% respectively. For subacromial impingement USG had sensitivity of 66.67%, specificity of 94.12%, positive predictive value of 50% and negative predictive value of 88.89%. For rotator cuff tear USG had sensitivity of 92.86%, specificity of 50%, positive predictive value of 81.25% and negative predictive value of 75% considering shoulder arthroscopy as gold standard.</p><p class="abstract"><strong>Conclusions:</strong> USG and MRI both are sensitive techniques for diagnosing of rotator cuff pathologies. USG has high accuracy in diagnosing partial thickness tears as compare to MRI. MRI proved to be superior in estimation of site and extent of tear. Considering shoulder arthroscopy as gold standard, it can be reserved for patients with suspicious of USG/MRI findings or those who may need surgical intervention simultaneously.</p>

PP141 Functional Connectivity Magnetic Resonance Imaging To Detect Autism

2019 ◽  
Vol 35 (S1) ◽  
pp. 64-65
Author(s):  
Mar Polo-DeSantos ◽  
Juan Pablo ◽  
Chalco Orrego ◽  
Ana Isabel Hijas-Gómez ◽  
Setefilla Luengo-Matos ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Connectivity ◽  
Predictive Value ◽  
Gold Standard ◽  
Neurodevelopmental Disorder ◽  
Negative Likelihood Ratio ◽  
Cochrane Library ◽  
Resonance Imaging ◽  
Functional Connections

IntroductionAutism is a neurodevelopmental disorder characterized by alterations in the intellectual, social, communication, and behavioral capabilities of an individual, and is rarely detected in children before 24 months of age. Early diagnosis and intervention may be more effective at a younger age. Functional connectivity magnetic resonance imaging (fcMRI) of 6-month old infants may be able to identify brain connection patterns related to at least one of the characteristics of autism, which normally appear at 24 months of age, by using a mathematical model to analyze the neuroimaging data.MethodsClinical studies published up to December 2018 that used fcMRI to detect autism in infants were reviewed. The literature databases searched included PubMed, Web of Science, the Trip Database, DynaMed, the Cochrane Library, the International Clinical Trials Registry Platform, and ClinicalTrials.gov. Early assessments of fcMRI analysis were identified through the Early Awareness and Alert System of the Agencia de Evaluación de Tecnologías Sanitarias.ResultsOnly one prospective study of 59 infants at 6-months of age was retrieved. A fcMRI analysis was performed to identify 2,635 pairs of functional connections from 230 brain regions. The infants were subsequently assessed for autism at 24 months of age using gold standard tests. The functional connections correlated with at least one of the behaviors related to autism evaluated at 24 months of age. Eleven infants (19%) were diagnosed with autism at 24 months. Compared with the gold standard test results, the predictive model achieved the following: sensitivity 0.82 (95% confidence interval [CI]: 0.52 - 0.95); specificity 1.00 (95% CI: 0.93–1.00); positive predictive value 1.00 (95% CI: 0.70–1.00); negative predictive value 0.96 (95% CI: 0.87–0.99); and negative likelihood ratio 0.18 (95% CI: 0.05–0.64). Adverse effects were not reported in the study.ConclusionsThe fcMRI analysis could help in early detection of autism and the development of preventive interventions. However, the evidence is sparse and more well-designed studies are needed.

scholarly journals Positive Predictive Value of Magnetic Resonance Imaging in Intradural Spinal Tumors Taking Histopathology as Gold Standard

2020 ◽  
Vol 24 (1) ◽  
Author(s):  
HAFEEZ-UR -REHMAN ◽  
ADNAN YOUSAF ◽  
MUHAMMAD USMAN ◽  
MUHAMMAD NOUMAN AKRAM
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Gold Standard ◽  
Spinal Tumor ◽  
Spinal Tumors ◽  
Radiology Department ◽  
Resonance Imaging ◽  
Female Ratio

Objective: To observe the positive predictive value of MRI, taking histopathology as gold standard in detecting spinal intradural tumors.Materials and Methods: Total 180 cases were included through non-probability purposive sampling, at Ganga Ram Hospital, Radiology department, Lahore. The radiological diagnosis obtained through MRI, was observed. The cases fit in inclusion criteria were underwent surgery and their histopathological findings were observed. Comparison between the outcomes of MRI and histopathology were undertaken, keeping histopathology as gold  standard. Positive predictive value of MRI in the diagnosis of intradural spinal tumor was calculated andpresented in the form of percentages and frequency.Results: There were total 180 patients presenting in OPD with the mean age of 45.71 ± 13.57 years. There were 112 (62%) male. Male to female ratio was 1.6:1. There were 134 (74.4%) cases who were positive for malignant spinal intradural tumor on histopathology showing the PPV of MRI as 74.4%.Conclusion: Magnetic Resonance Imaging is very beneficial imaging tool for early diagnosis of spinal cord tumors.

Accuracy of magnetic resonance imaging of inguinofemoral lymph nodes in vulval cancer

2006 ◽  
Vol 16 (3) ◽  
pp. 1179-1183 ◽  
Author(s):  
K. Singh ◽  
C. O. Orakwue ◽  
H. Honest ◽  
M. Balogun ◽  
C. Lopez ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Lymph Nodes ◽  
Likelihood Ratio ◽  
Predictive Value ◽  
Test Accuracy ◽  
High Morbidity ◽  
Resonance Imaging ◽  
Vulval Cancer ◽  
Inguinofemoral Lymphadenectomy

Inguinofemoral lymphadenectomy contributes to the high morbidity related to surgical treatment of vulval cancer. The objective of this study was to assess the accuracy of magnetic resonance imaging (MRI) in predicting inguinofemoral lymph nodes metastasis in women with vulval cancer. We reviewed the clinical, MRI, surgical, and pathologic findings of 59 women with vulval cancer who were treated at our institution from January 2000 to June 2004. Histology was available for 39 women who had undergone inguinofemoral lymphadenectomy. Clinical and MRI findings were compared with histology result to assess test accuracy. MRI had a positive likelihood ratio (LR+) of 4.8 (95% confidence interval of 2.7–8.6) and negative likelihood ratio (LR−) of 0.17 (0.06–0.49). It had a sensitivity of 85.7% (63.7–97), specificity of 82.1% (69.6–91.1), positive predictive value (PPV) of 64.3% (44.1–81.4), and negative predictive value (NPV) of 93.9% (83.1–98.7). Clinical examination had an LR+ of 6.1 (1.8–21.6) and LR− of 0.69 (0.5–0.96). It had a sensitivity of 35% (15.3–59.4), specificity of 94.3% (84.3–98.8), PPV of 70% (34.7–93.3), and NPV of 79.4% (67.3–88.5). Kappa statistics for interobserver and intraobserver agreement were 0.9091 and 0.8475, respectively. MRI assessment was accurate in predicting negative nodal status that is clinically useful in identifying women who can be spared inguinofemoral lymphadenectomy. It is noninvasive and is superior to clinical assessment. In clinical practice, this should encourage toward nodal sparing surgery, thus lowering surgical-related patient morbidity.

scholarly journals ACOUSTIC NEUROMA;

2019 ◽  
Vol 26 (04) ◽  
Author(s):  
Nazish Hameed ◽  
Muhammad Tahir ◽  
Noureen Jahangir ◽  
Hassan Bukhari ◽  
Hira Bukhari
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Acoustic Neuroma ◽  
Predictive Value ◽  
Gold Standard ◽  
Imaging Modality ◽  
Whole Body ◽  
Resonance Imaging ◽  
Cross Sectional Survey

Objectives: To determine the diagnostic accuracy of magnetic resonance imaging in the detection of acoustic neuroma taking histopathology as gold standard. Study Design: Cross-sectional survey. Setting: This study was carried out at the Department of Diagnostic Radiology, Lahore General Hospital, Lahore. Duration of Study with Dates: Study was completed in six months after approval of synopsis from 14-07-2009 to 14-01-2010. Subjects & Methods: This study comprised of 55 patients with clinical suspicion acoustic neuroma. Magnetic resonance imaging on a 1.5-T Philips whole body magnetic resonance system was performed. The cases were operated and histopathological results were recorded. The results of magnetic resonance imaging and histopathology were compared taking histopathology as gold standard. Results: Out of 55 patients, 43 patients (78.2%) had acoustic neuroma on magnetic resonance imaging. After comparison of results of magnetic resonance imaging with histopathology, the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of magnetic resonance imaging were 97.7%, 91.7%, 97.7%, 91.7% and 96.4% respectively. Conclusion: Magnetic resonance imaging is a highly accurate, non-invasive, safe and convenient imaging modality for the evaluation of acoustic neuromas and is valuable for guiding surgical biopsies thereby decreasing unnecessary intervention. It allows detection of small tumours which is very useful in tumour characterization and plays an integral role in early detection, planning management and estimating patient’s prognosis.

Evaluating Accuracy of Plain Magnetic Resonance Imaging or Arthrogram versus Wrist Arthroscopy in the Diagnosis of Scapholunate Interosseous Ligament Injury

2020 ◽  
Author(s):  
Nardeen Kader ◽  
Mohammed Shoaib Arshad ◽  
Pawan K. Chajed ◽  
Daoud Makki ◽  
Kiran Naikoti ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Predictive Value ◽  
Gold Standard ◽  
Ligament Injury ◽  
Wrist Arthroscopy ◽  
Resonance Imaging ◽  
Interosseous Ligament ◽  
Diagnostic Arthroscopy ◽  
Magnetic Resonance Imaging Mri

Abstract Introduction Scapholunate interosseous ligament injury (SLIL) is the most common cause of wrist instability and a cause of morbidity in a proportion of patients with wrist injuries. Aim To evaluate the accuracy of plain magnetic resonance imaging (MRI) and MR arthrogram (MRA) in the diagnosis of SLIL injury against the existing gold standard-wrist arthroscopy. Materials and Methods We retrospectively reviewed 108 cases by comparing MRI/MRA reports and their wrist arthroscopy operation notes. Results Overall MRI sensitivity to SLIL injuries was 38.5% (91.0% specificity). When broken down into plain MRI and MRA the results were: plain MRI sensitivity = 19.2% (91.4% specificity) and MRA sensitivity = 57.7% (90.5% specificity). Conclusion Neither MRI nor MRA scanning is sensitive enough compared with the gold standard. Positive predictive value remains too low (62.5 and 88.2%, respectively) to consider bypassing diagnostic arthroscopy and treating surgically. The negative predictive value (60.4 and 63.6%, respectively) is inadequate to confirm exclusion of injury from MRI results alone.

Prostate imaging reporting and data system correlation with Gleason score: Pathological aspects of magnetic resonance imaging findings

2019 ◽  
Vol 86 (4) ◽  
pp. 189-196 ◽  
Author(s):  
Patricia Yokoo ◽  
Gabriel Lucca de Oliveira Salvador ◽  
Jesus José André Quintana Castillo ◽  
Ana Carolina Nicoletti Basso ◽  
Rafael Sarmento do Amaral ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Confidence Interval ◽  
Likelihood Ratio ◽  
Predictive Value ◽  
Data System ◽  
Imaging Findings ◽  
Resonance Imaging ◽  
Prostate Imaging

Objective: Prostate cancer has a high prevalence and mortality, being the most diagnosed urologic cancer. Prostatic magnetic resonance imaging showed high sensitivity in the detection of clinically significant neoplasia and agreement with the Gleason score. Therefore, we attempted to evaluate the diagnostic accuracy of the prostate imaging reporting and data system, using biopsy and prostatectomy as the reference standard. The secondary goal of correlating prostatic magnetic resonance imaging findings and anatomopathological samples is obtained. Materials and Methods: We retrospectively analyzed seventy-nine 1.5 Tesla prostatic magnetic resonance imaging scans in patients aged 31 to 86 years, performed at the Clinical Hospital of the Federal University of Paraná between January 2015 and February 2018. Results: Considering all 79 patients, prostatic magnetic resonance imaging was able to diagnose tumor in 47 patients (59.4%). Considering the peripheral zone, the prostatic magnetic resonance imaging had a sensitivity of 75.0% (95% confidence interval: 52.1%–98.0%), specificity of 89.5% (95% confidence interval: 66.0%–100%), 94.4% positive predictive value (95% confidence interval: 71.0%–100%), 66.7% negative predictive value (95% confidence interval: 43.0%–69.0%), 83.8% Positive Likelihood Ratio (PVR) (95% confidence interval: 60.0%–100%), 27.9% Negative Likelihood Ratio (RVN) (95% confidence interval: 5.0%–50.0 %), and accuracy of 86.3% (95% confidence interval: 63.0%–100%). The receiver operating characteristic curve obtained demonstrated the sensitivity variation according to the prostate imaging reporting and data system score of the patients, obtaining an area under the curve of 84.8 for a prostate imaging reporting and data system cutoff of 3. Conclusion: The use of the prostate imaging reporting and data system score is useful for the screening and classification of prostate cancer, due to its easy reproducibility, even in a population with an unknown prostate cancer prevalence, which can be easily correlated with biopsy studies and/or radical prostatectomy.

scholarly journals A comparative study between magnetic resonance imaging and transvaginal sonography for evaluation of uterine fibroid using histopathology as a gold standard

2020 ◽  
Vol 8 (6) ◽  
pp. 2173
Author(s):  
Alka Goyal ◽  
Deeksha Mehta ◽  
Naresh K. Mangalhara ◽  
Sunita Poonia
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Gold Standard ◽  
Statistical Tests ◽  
Uterine Fibroids ◽  
Transvaginal Sonography ◽  
Resonance Imaging ◽  
Clinical Practices ◽  
Diagnostic Modality ◽  
Sensitivity Specificity

Background: Uterine fibroids constitute a substantial bulk of patients presenting to Gynaecology department. Many newer imaging modalities have evolved for their correct evaluation, but in a developing country like India, ultrasound is still being used as a screening as well as diagnostic modality. So, this study was done to compare ultrasound and magnetic resonance imaging for evaluation of uterine fibroids in terms of their sensitivity, specificity Trans vaginal  and positive predictive value using Histopathology as a gold standard so as to improvise on current clinical practices in this country.Methods: An ethically approved prospective study was done upon 50 patients with suspected uterine masses at SMS Hospital Jaipur. All included patients underwent Trans vaginal Ultrasound (TVS) and Magnetic resonance imaging (MRI) and were accordingly treated surgically. Histopathology report was traced postoperatively. Data was collected and subjected to various statistical tests including Cohen’s kappa.Results: Most of the patients were <50 years and presented with complains of pain abdomen. Among total 50 cases, the sensitivity of TVS and MRI was 44% and 92%, specificity was 96% and 88%, PPV was 91.67% and 88.46%, NPV was 63.16% and 91.67% respectively, kappa was 0.40 and 0.80 i.e. agreement between TVS and MRI v/s HPE was 40% and 80% respectively. The diagonal agreement between transvaginal USG and MRI, was 63%.Conclusions: TVS is a good screening modality but MRI is definitely better for proper characterization and localization of fibroids enabling clinicians to select the most appropriate management in everyday clinical practice.

Сauses of Dizziness in Patients with Suspected Stroke

2018 ◽  
Vol 7 (3) ◽  
pp. 217-221
Author(s):  
E. V. Shevchenko ◽  
G. R. Ramazanov ◽  
S. S. Petrikov
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Demyelinating Disease ◽  
Heart Rhythm ◽  
Diagnostic Methods ◽  
Deficiency Anemia ◽  
Resonance Imaging ◽  
Peripheral Vestibulopathy ◽  
Suspected Stroke ◽  
The Brain

Background Acute dizziness may be the only symptom of stroke. Prevalence of this disease among patients with isolated dizziness differs significantly and depends on study design, inclusion criteria and diagnostic methods. In available investigations, we did not find any prospective studies where magnetic resonance imaging, positional maneuvers, and Halmagyi-Curthoys test had been used to clarify a pattern of diseases with isolated acute dizziness and suspected stroke.Aim of study To clarify the pattern of the causes of dizziness in patients with suspected acute stroke.Material and methods We examined 160 patients admitted to N.V. Sklifosovsky Research Institute for Emergency Medicine with suspected stroke and single or underlying complaint of dizziness. All patients were examined with assessment of neurological status, Dix-Hollpike and Pagnini-McClure maneuvers, HalmagyiCurthoys test, triplex scans of brachiocephalic arteries, transthoracic echocardiography, computed tomography (CT) and magnetic resonance imaging (MRI) of the brain with magnetic field strength 1.5 T. MRI of the brain was performed in patients without evidence of stroke by CT and in patients with stroke of undetermined etiology according to the TOAST classification.Results In 16 patients (10%), the cause of dizziness was a disease of the brain: ischemic stroke (n=14 (88%)), hemorrhage (n=1 (6%)), transient ischemic attack (TIA) of posterior circulation (n=1 (6%)). In 70.6% patients (n=113), the dizziness was associated with peripheral vestibulopathy: benign paroxysmal positional vertigo (n=85 (75%)), vestibular neuritis (n=19 (17%)), Meniere’s disease (n=7 (6%)), labyrinthitis (n=2 (1,3%)). In 6.9% patients (n=11), the cause of dizziness was hypertensive encephalopathy, 1.9% of patients (n=3) had heart rhythm disturbance, 9.4% of patients (n=15) had psychogenic dizziness, 0.6% of patients (n=1) had demyelinating disease, and 0.6% of patients (n=1) had hemic hypoxia associated with iron deficiency anemia.Conclusion In 70.6% patients with acute dizziness, admitted to hospital with a suspected stroke, peripheral vestibulopathy was revealed. Only 10% of patients had a stroke as a cause of dizziness.

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