A Nano-Gap Nano-Antenna for Enhancing the Spatial Resolution of Optical Brain Imaging

2020 ◽  
Vol 15 (1) ◽  
pp. 24-31
Author(s):  
Zeshan Shoaib ◽  
Junhyun Kim ◽  
M. Ahmad Kamran ◽  
Myung Yung Jeong
Keyword(s):  
Brain Imaging ◽  
Spatial Resolution ◽  
Biomedical Imaging ◽  
Near Infrared ◽  
Low Cost ◽  
Resolution Enhancement ◽  
Separation Distance ◽  
Imaging Systems ◽  
Infrared Light ◽  
Near Infrared Light

Optical brain imaging has the potential for a bright future thanks to its low cost and portability relative to other biomedical imaging modalities. Temporal and spatial resolutions are considered to be the discriminatory features for selection of biomedical imaging equipment. Optical brain imaging systems, however, still face the bottleneck of limited spatial resolution. In this study, a novel method for guiding near infrared light at one of two particular gaps spaced nanometers apart has been presented. It includes the design of a nanogap nano-antenna for measurement of overlapping information on vicinities of only nanoscale separation distance, which could result in enhancement of the spatial resolution of optical brain imaging systems. The design of the proposed nano-gap nano-antenna channels near-infrared light to a specific path among two gaps separated by a nanometer-scale distance. A supportive analysis of gap design also is presented in this study. Additionally, the results of a comprehensive analysis of the behavior of light through the designed nano-gap nano-antenna are provided. The proposed methodology is a practical substitute for a high-density probe arrangement as well as a possible means of spatial resolution enhancement.

scholarly journals Age-related changes in diffuse optical tomography sensitivity profiles in infancy

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0252036
Author(s):  
Xiaoxue Fu ◽  
John E. Richards
Keyword(s):  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Hemoglobin Concentration ◽  
Separation Distance ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Photon Propagation ◽  
Age Related ◽  
Wide Range

Diffuse optical tomography uses near-infrared light spectroscopy to measure changes in cerebral hemoglobin concentration. Anatomical interpretations of the location that generates the hemodynamic signal requires accurate descriptions of diffuse optical tomography sensitivity to the underlying cortical structures. Such information is limited for pediatric populations because they undergo rapid head and brain development. The present study used photon propagation simulation methods to examine diffuse optical tomography sensitivity profiles in realistic head models among infants ranging from 2 weeks to 24 months with narrow age bins, children (4 and 12 years) and adults (20 to 24 years). The sensitivity profiles changed systematically with the source-detector separation distance. The peak of the sensitivity function in the head was largest at the smallest separation distance and decreased as separation distance increased. The fluence value dissipated more quickly with sampling depth at the shorter source-detector separations than the longer separation distances. There were age-related differences in the shape and variance of sensitivity profiles across a wide range of source-detector separation distances. Our findings have important implications in the design of sensor placement and diffuse optical tomography image reconstruction in (functional) near-infrared light spectroscopy research. Age-appropriate realistic head models should be used to provide anatomical guidance for standalone near-infrared light spectroscopy data in infants.

scholarly journals Near-infrared-light-induced decomposition of Rhodamine B triggered by localized surface plasmon at gold square dimers with well-defined separation distance

AIP Advances ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 035153 ◽  
Author(s):  
Satoshi Kaneko ◽  
Shuhei Watanabe ◽  
Shinya Kasai ◽  
Tomoaki Nishino ◽  
Kazuhito Tsukagoshi ◽  
...  
Keyword(s):  
Surface Plasmon ◽  
Rhodamine B ◽  
Near Infrared ◽  
Separation Distance ◽  
Infrared Light ◽  
Localized Surface Plasmon ◽  
Near Infrared Light ◽  
Induced Decomposition

scholarly journals Near-infrared light excited photodynamic anticancer therapy based on UCNP@AIEgen nanocomposite

2021 ◽  
Author(s):  
Shihui Ding ◽  
Wenbo Wu ◽  
Tingting Peng ◽  
Wen Pang ◽  
Pengfei Jiang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Penetration Depth ◽  
Spatial Resolution ◽  
Treatment Strategy ◽  
Side Effect ◽  
Near Infrared ◽  
High Spatial Resolution ◽  
Anticancer Therapy ◽  
Infrared Light ◽  
Near Infrared Light

Photodynamic therapy (PDT), one clinically approved treatment strategy, is featured with non-invasiveness, low side-effect, high spatial resolution, etc. The advancement of PDT is significantly restricted by the penetration depth of...

An ordered copper nanowell-array film with near-perfect broadband absorption from ultraviolet to near-infrared light

2020 ◽  
Vol 59 (11) ◽  
pp. 110906
Author(s):  
Juan Shen ◽  
Yong Ren ◽  
Xinxin Zhu ◽  
Min Mao ◽  
Quan Zhou ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Broadband Absorption

scholarly journals Recent Near-Infrared Light-Activated Nanomedicine toward Precision Cancer Therapy

2021 ◽  
Author(s):  
Xiaowei Luan ◽  
Yongchun Pan ◽  
Yanfeng Gao ◽  
Yujun Song
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Human Society ◽  
Near Infrared Light ◽  
History Of ◽  
The Universe

Light has witnessed the history of mankind and even the universe. It is of great significances to the life of human society, contributing to energy, agriculture, communication, and much more....

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