Giant Functioning Cervicomediastinal Parathyroid Cyst

1979 ◽  
Vol 88 (4) ◽  
pp. 545-549 ◽  
Author(s):  
George Buchanan ◽  
Monica M. Gregory
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Rare Case ◽  
Cystic Mass ◽  
Large Cyst ◽  
High Concentration ◽  
Serum Parathyroid Hormone ◽  
Parathyroid Cyst ◽  
Clinical Investigations ◽  
Cyst Aspiration

A rare case of a large cervicomediastinal parathyroid cyst associated with hypercalcemia and an elevation of serum parathyroid hormone is presented. The pathogenesis of such a large cyst is discussed, hemorrhage into an adenoma being the most likely cause. Clinical investigations which should be carried out for any cystic mass at the root of the neck should include a serum calcium, and if this is found to be elevated, the possibility of the cyst being of parathyroid origin should be considered. In view of the high concentration of parathyroid hormone found within the cyst, aspiration of the cyst contents for parathyroid hormone estimation might well prove a valuable test to confirm the diagnosis.

Impact of pre-operative serum 25-hydroxyvitamin D on post-operative serum calcium in patients undergoing total thyroidectomy for benign goitre: retrospective study of 246 patients

2017 ◽  
Vol 131 (10) ◽  
pp. 925-929 ◽  
Author(s):  
M Erlem ◽  
N Klopp-Dutote ◽  
A Biet-Hornstein ◽  
V Strunski ◽  
C Page
Keyword(s):  
Parathyroid Hormone ◽  
Retrospective Study ◽  
Total Thyroidectomy ◽  
Serum Calcium ◽  
Univariate Analysis ◽  
Multinodular Goitre ◽  
Serum Parathyroid Hormone ◽  
Single Centre ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

AbstractObjective:To determine whether pre-operative serum 25-hydroxyvitamin D has an impact on post-operative parathyroid hormone and serum calcium levels in patients undergoing total thyroidectomy for benign goitre.Methods:This single-centre, retrospective study comprised 246 unselected surgical patients who had undergone total thyroidectomy for bilateral, benign, multinodular goitre. The correlation between pre-operative serum 25-hydroxyvitamin D and post-operative serum parathyroid hormone and serum calcium was studied to determine whether low pre-operative serum 25-hydroxyvitamin D was predictive of post-operative hypocalcaemia.Results:Seventy-nine patients (32 per cent) had post-operative hypocalcaemia. Eighteen patients (7.32 per cent) experienced unintentional parathyroidectomy (1 parathyroid gland in 15 patients, 2 parathyroid glands in 3 patients). In univariate analysis, pre-operative serum 25-hydroxyvitamin D was not correlated with post-operative serum calcium (p = 0.69) or post-operative serum parathyroid hormone (p = 0.5804). Furthermore, in multivariate analysis, which took into account unintentional parathyroidectomy, no correlation was found (p = 0.33). Bilateral unintentional parathyroidectomy was statistically associated with post-operative hypocalcaemia (p = 0.032).Conclusion:Pre-operative serum 25-hydroxyvitamin D did not appear to have any impact on post-operative serum calcium in patients undergoing total thyroidectomy for benign goitre.

scholarly journals The study in the relationship between serum calcium and serum parathyroid hormone(PTH) by employing the various kits of PTH assay.

RADIOISOTOPES ◽  
1987 ◽  
Vol 36 (10) ◽  
pp. 538-541
Author(s):  
Kazutami TORIZUMI ◽  
Hirofumi AIBATA ◽  
Yoshiyuki TANIGUCHI ◽  
Shigeyuki KIJI ◽  
Akitaka UEYOSHI ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Serum Parathyroid Hormone ◽  
The Relationship

scholarly journals Parathyroid hormone in Sri Lankan pregnant women: Vitamin D and other determinants

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258381
Author(s):  
Anusha Kaneshapillai ◽  
Usha Hettiaratchi ◽  
Shamini Prathapan ◽  
Guwani Liyanage
Keyword(s):  
Vitamin D ◽  
Regression Analysis ◽  
Parathyroid Hormone ◽  
Pregnant Women ◽  
Serum Calcium ◽  
Educational Level ◽  
Venous Blood ◽  
Sri Lankan ◽  
Serum Parathyroid Hormone ◽  
Cross Sectional

Introduction Determinants of parathyroid hormone level during pregnancy have been less frequently studied. We aimed to describe the serum parathyroid hormone (PTH) and its determinants in Sri Lankan pregnant women in a community setting. Materials and methods In this cross-sectional analysis, 390 pregnant mothers in their third trimester were enrolled from primary care centers of 15 health divisions in the Colombo District in Sri Lanka. Venous blood was analyzed for a total 25-hydroxyvitamin-D [25(OH)D], serum parathyroid hormone (PTH), serum calcium, and alkaline phosphatase. The bone quality was assessed in terms of speed of sound (SOS) using the quantitative ultrasound scan (QUS). Univariate and multivariate regression analysis was used to examine the determinants of PTH concentration in blood. Results Median serum 25(OH)D was 17.5ng/mL. Most (61.6%) were vitamin D deficient (<20ng/mL). Median PTH was 23.7pg/mL. Only 0.8% had hyperparathyroidism (PTH >65pg/mL). The correlation between 25(OH)D and PTH was weak but significant (r = -0.197; p<0.001). SOS Z-score was below the cut-off (≤−2) in fifty-six women (14.7%), and SOS did not relate significantly to PTH. In regression analysis, serum 25(OH)D, serum calcium, body mass index, educational level, and weeks of pregnancy were significant independent variables when adjusted. The model explained 16% of the variation in the PTH level. Conclusions A high prevalence of vitamin D deficiency was observed among Sri Lankan pregnant women in the present study. Serum 25(OH)D, calcium, weeks of pregnancy, and educational level were determinants of serum PTH.

scholarly journals A rare case of a parathyroid adenoma inside a parathyroid cyst

2014 ◽  
Vol 58 (7) ◽  
pp. 776-778 ◽  
Author(s):  
Spyridon N. Karras ◽  
Ioannis Koutelidakis ◽  
Panagiotis Anagnostis ◽  
Gesthimani Mintziori ◽  
Nikolaos Pontikides ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Therapeutic Approach ◽  
Rare Case ◽  
Cervical Lesions ◽  
Parathyroid Cyst ◽  
Parathyroid Cysts

Parathyroid cysts (PCs) are rare lesions, located in the neck and anterior mediastinal region. The vast majority are non-functioning, presented as nodular cervical lesions. Large, non-functioning PCs can manifest with compressive symptoms of the surrounding tissues. Rarely, PCs produce excessive amounts of parathyroid hormone (PTH), resulting in primary hyperparathyroidism. We report a case of functional PC, describing its diagnostic and therapeutic approach.

Serum parathyroid hormone levels and serum calcium levels from birth to senescence

1976 ◽  
Vol 5 ◽  
pp. 289-304 ◽  
Author(s):  
Betty S. Roof ◽  
Carolyn F. Piel ◽  
James Hansen ◽  
H.Hugh Fudenberg
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Serum Parathyroid Hormone ◽  
Hormone Levels

scholarly journals Study of prevalence of secondary hyperparathyroidism in chronic renal failure in hadoti region

2019 ◽  
Vol 7 (8) ◽  
pp. 2903
Author(s):  
Chiranjee Lal Dayma ◽  
Devendra Ajmera ◽  
Shiv Charan Jelia ◽  
Pankaj Jain
Keyword(s):  
Renal Failure ◽  
Parathyroid Hormone ◽  
Chronic Renal Failure ◽  
Secondary Hyperparathyroidism ◽  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Hormone Level ◽  
Serum Parathyroid Hormone ◽  
The Difference

Background: Secondary hyperparathyroidism is known and early complication of chronic renal failure patients. Aim of this study was to assess the prevalence of secondary hyperparathyroidism and correlation between serum parathyroid hormone level with biochemical parameters in renal failure patients in tertiary care hospital in Kota, Rajasthan.Methods: A cross sectional observational study was carried out in 50 patients who had creatinine clearance of 30ml/min/1.73m2 or less for greater than 6 weeks attended the OPD of department of General Medicine, New Medical College hospital, Kota, Rajasthan from May 2018 to November 2018. Investigations like complete blood count, renal function test, urine routine microscopy and USG abdomen with serum parathyroid hormone, serum phosphorus, serum calcium levels were done. Serum parathyroid hormone level was done by calorimetric method.Results: The prevalence of secondary hyperparathyroidism in our study was 72%.In hyperparathyroidism patient’s serum calcium level was low and the difference was highly significant (p<0.001). There is negative correlation between S.PTH and S. calcium level (r=-0.536). Mean serum calcium level in our study is 1.6mmol/l. In hyperparathyroidism patient’s serum phosphate level was high and the difference was highly significant (p<0.001). There was positive correlation between S.PTH and S.PO4 level (r=0.402). Mean serum phosphorus level in our study is 5.7 mg/dl. Prevalence of hyperparathyroidism was high among CRF patients with normal BP than hypertensive patients and with normal sugar than diabetics but the difference in proportion was not significant (p=0.87, p=0.98 respectively). 90% patients were on haemodialysis while 10% patients were on conservative management.Conclusions: Early detection of secondary hyperparathyroidism in chronic renal failure patients can reduce its complications like bone fracture and cardiovascular complications.

Decline in serum calcium, magnesium, and phosphorus values with oral glucose in normal neonates: Studies of serum parathyroid hormone and calcitonin

1986 ◽  
Vol 108 (4) ◽  
pp. 607-610 ◽  
Author(s):  
Pankaja S. Venkataraman ◽  
Kenneth E. Blick ◽  
Radhakrishna Rao ◽  
Henry D. Fry ◽  
Michael K. Parker
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Oral Glucose ◽  
Serum Parathyroid Hormone ◽  
Calcium Magnesium ◽  
Normal Neonates

scholarly journals Serum parathyroid hormone level is associated with body mass index. The 5th Tromso study

2004 ◽  
pp. 167-172 ◽  
Author(s):  
E Kamycheva ◽  
J Sundsfjord ◽  
R Jorde
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Relative Risk ◽  
Body Mass ◽  
Serum Calcium ◽  
Population Based ◽  
Serum Parathyroid Hormone ◽  
Serum Pth

OBJECTIVE: To study whether serum parathyroid hormone (PTH) and serum calcium are associated with body mass index (BMI), and their predicting role in obesity. DESIGN: Population based, cross-sectional study. METHODS: In 2001 a population-based health survey was held in Tromso, North Norway. Questionnaires on medical history and life-style factors were completed and anthropometric data were collected. Calcium and vitamin D intakes and a physical activity score were calculated. Serum calcium and PTH were measured in a subset of 3447 men and 4507 women. Pearson correlation and linear regression were used to evaluate associations between BMI, PTH and serum calcium, and logistic regression was used to test PTH and serum calcium as predictors of obesity and to calculate odds ratio. Relative risk was calculated using frequency tables. RESULTS: For serum calcium and PTH there was a significant positive relation to BMI in both genders (P<0.001), which to our knowledge has not previously been reported on the basis of a large epidemiological study. Age, low calcium and vitamin D intakes were explanatory variables for serum PTH. The highest quartile of serum PTH (>4.20 pmol/l) was a significant predictor for obesity (P<0.001) in both genders, adjusted for age, physical activity and serum calcium. Obesity rates were higher in those with PTH levels in the highest quartile compared with those in the lower quartiles, which resulted in a relative risk of 1.40 (95% confidence interval (C.I.) 1.20-1.60) for men and 1.48 (95% C.I. 1.31-1.67) for women. CONCLUSIONS: Serum PTH, adjusted for age, physical activity and serum calcium, is positively associated with BMI in both sexes, and serum PTH is an independent predictor of obesity in our statistical model.

scholarly journals OBSERVATION OF SERUM PARATHYROID HORMONE AND SERUM IONISED CALCIUM IN PATIENTS OF RENAL STONE

2020 ◽  
pp. 1-3
Author(s):  
Sanjeev Kumar ◽  
Vishwa Prakash Jha ◽  
N. K. Mishra ◽  
Debarshi Jana
Keyword(s):  
Parathyroid Hormone ◽  
Serum Calcium ◽  
Calcium Level ◽  
Renal Stone ◽  
Stone Formation ◽  
Life Time ◽  
Metabolic Factors ◽  
Serum Parathyroid Hormone ◽  
Stone Formers ◽  
Ionised Calcium

Background: The life time prevalence of renal stone is estimated to be between 1 to 15 %. Symptomatic renal calculi pose a serious health problem to the patients and increase economic burden worldwide. The aim of the study is to observe the level of serum parathyroid hormone and serum ionised calcium in patients with renal stones. Methods: A total of 50 patients with the diagnosis of renal stone who came to MMCH, Madhubani, were evaluated for serum parathyroid hormone and serum ionised calcium level. Results: Serum parathyroid hormone was raised above the normal range in 2 out of 50 patients and serum calcium level was elevated in 12 patients, while phosphate, sodium, potassium, creatinine and blood urea were higher than the normal. Most of the urinary parameters were similar to other studies stating that they play an important role in renal stone formation. Conclusions: Although the pathogenesis of renal stone is multifactorial, metabolic factors do play an important role in their formation in both groups of population; first time stone formers as well as recurrent stone formers. Parathyroid hormone level, along with other metabolic factors like serum calcium, phosphate, uric acid and others should be assessed to know the exact pathology. Besides identifying anomalies, the evaluation also helps in determining the choice of treatment.

Effect of calcitonin on salivary phosphorus and calcium excretion in sheep

1984 ◽  
Vol 102 (3) ◽  
pp. 365-368 ◽  
Author(s):  
T. Matsui ◽  
Y. Kanagawa ◽  
H. Yano ◽  
R. Kawashima
Keyword(s):  
Parathyroid Hormone ◽  
Cyclic Amp ◽  
Serum Calcium ◽  
Salivary Secretion ◽  
Calcium Excretion ◽  
Serum Concentrations ◽  
Serum Parathyroid Hormone ◽  
Phosphorus Excretion ◽  
Parotid Duct ◽  
Secretion Rates

ABSTRACT Three thyroidectomized sheep were infused intravenously with porcine calcitonin at a rate of 30 mi.u./h per kg and three sham-operated sheep were infused with vehicle for 5 h. Saliva was collected from the left parotid duct by cannulation for 10 min in every hour. Salivary secretion rates were not changed in either thyroidectomized or sham-operated sheep throughout the experiment. Before the infusion, salivary phosphorus excretion was less in thyroidectomized sheep than in sham-operated animals. Calcitonin infusion increased salivary phosphorus excretion and decreased serum phosphorus concentrations in thyroidectomized sheep. Vehicle infusion did not affect salivary phosphorus excretion in sham-operated sheep. Serum concentrations and salivary excretion of calcium were decreased by calcitonin infusion into thyroidectomized sheep but were not changed in sham-operated sheep infused with vehicle. Calcitonin infusion increased serum parathyroid hormone concentrations in thyroidectomized sheep after the decrease of serum calcium concentrations. However, vehicle infusion did not affect serum parathyroid hormone concentrations in sham-operated sheep. There was little change of cyclic AMP excretion during the experiment in either thyroidectomized or sham-operated sheep. It is concluded that calcitonin increases salivary phosphorus excretion in sheep. J. Endocr. (1984) 102, 365–368

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