Subgroups with typical courses of depressive symptoms in an elderly population during 13 years of observation: Results from the Heinz Nixdorf Recall Study

2020 ◽  
Vol 66 (8) ◽  
pp. 799-809
Author(s):  
Miriam Engel ◽  
Karl-Heinz Jöckel ◽  
Nico Dragano ◽  
Miriam Engels ◽  
Susanne Moebus
Keyword(s):  
Depressive Symptoms ◽  
Short Form ◽  
Empirical Studies ◽  
Depression Scale ◽  
Population Based ◽  
Epidemiologic Studies ◽  
Depression Score ◽  
Mean Values ◽  
Heinz Nixdorf Recall Study ◽  
Large Fluctuations

Background: Depressive symptoms are volatile over time but empirical studies of intra-individual variations of depressive symptoms over longer periods are sparse. Aims: We aim to examine fluctuation patterns of depressive symptoms and to investigate the possible influence of age, sex and socioeconomic factors on fluctuation in a population-based sample over a period of 13 years. Methods: We used data of 4,251 participants (45–75 years; 51.0% women at baseline) of the Heinz Nixdorf Recall Study with at least two of nine possible measurements obtained in the period between 2000 and 2017. Depressive symptoms were assessed via the Center for Epidemiologic Studies Depression Scale (CES-D) short form. Based on the individual mean values and standard deviation from all measurements, we categorized participants as G1 ‘stable low’, G2 ‘stable high’, G3 ‘stable around cutoff’ and G4 ‘large fluctuations’. Results: Most participants (82.3%) showed stable low depressive symptoms (G1), whereas 2.3% performed stable high values (G2), 6.9% stable around the cutoff (G3) and 8.6% large fluctuations (G4). Conclusion: Our longitudinal results reveal that almost 18% (G2, G3 and G4) of the participants have an increased depression score or strong fluctuations at times. According to our classification, a higher proportion of the participants show anomalies with regard to depression compared to a simple classification into depressed and nondepressed, especially if this is based on a single measurement. Thus, longitudinal measurements of depression can prevent misclassification and provide valuable information about the course of depressive symptoms for a better understanding of the changes of depression.

scholarly journals Validation of the Japanese Version of the Center for Epidemiologic Studies Depression Scale—Revised: A Preliminary Analysis

2021 ◽  
Vol 11 (8) ◽  
pp. 107
Author(s):  
Hirohito Tsuboi ◽  
Yui Takakura ◽  
Hiromasa Tsujiguchi ◽  
Sakae Miyagi ◽  
Keita Suzuki ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Depressive Symptoms ◽  
Native Speakers ◽  
Depression Scale ◽  
Japanese Version ◽  
Population Based ◽  
Epidemiologic Studies ◽  
Community Dwelling ◽  
Two Factors ◽  
Study Population

To make the Japanese version of the CESD-R—a revised version of the Center for Epidemiologic Studies depression scale (CES-D)—in the assessment of depressive symptoms in a general population. The English version of CESD-R was translated into Japanese, and back-translated into English by three native speakers of Japanese and English; then, we selected the version most completely consistent with the original items. The CESD-R was applied to 398 community-dwelling people (191 men: 48.0%, and 207 women: 52.0%) who were over 40 years old. The Japanese version of the CES-D was also carried out in the same population. Factor analysis was performed. Additionally, the correlations between the CESD-R and CES-D results were identified. The CESD-R scores showed a significantly positive correlation with CES-D scores (r = 0.74, p < 0.0005). Analysis of the CESD-R yielded a Cronbach’s alpha result of 0.90. Factor analysis revealed one principal factor in the CESD-R, whereas the original CES-D had two factors because of reversed items. The Japanese version of the CESD-R appears to have the reliability to be applicable for assessing depressive symptoms in population-based samples. However, because the Japanese expressions for some items might be unusual, our study population was also limited; further studies on other populations and on incorporating improved Japanese terminology will be needed.

Pathways Between Acculturation and Health

2011 ◽  
Vol 33 (4) ◽  
pp. 524-539 ◽  
Author(s):  
Patricia Y. Miranda ◽  
Hector M. González ◽  
Wassim Tarraf
Keyword(s):  
Depressive Symptoms ◽  
Cognitive Function ◽  
Structural Equation ◽  
Structural Equation Models ◽  
Depression Scale ◽  
The Elderly ◽  
Population Based ◽  
Epidemiologic Studies ◽  
Functional Health ◽  
Cross Sectional

The purpose of this study was to assess the association between acculturation and functional health using multiple proxies of acculturation to examine explanatory pathways to clarify disparate health findings. A population-based cross-sectional, multistage probability sample from the Hispanic Established Populations for the Epidemiologic Studies of the Elderly ( N = 3,050) was used. The dependent variables of neuropsychiatric function were depressive symptoms (Center for Epidemiologic Studies Depression Scale [CES-D]) and cognitive function (mini-mental state examination [MMSE]) examined in separate multivariable regression and structural equation models to examine the pathways between acculturation proxies and neuropsychiatric function. Findings indicated that three acculturation proxies were associated with cognitive function but none were associated with depressive symptoms. English proficiency fully mediated the associations between other acculturation proxies and cognitive function. The findings suggest that language plays a central role in the pathway between acculturation and health among Mexican-origin populations.

scholarly journals Methylation Related to Perceived Parenting in Adolescents and its Association to Depressive Symptoms Two Years Later

2017 ◽  
Vol 41 (S1) ◽  
pp. S307-S307
Author(s):  
E. Van Assche ◽  
E. Vangeel ◽  
K. Freson ◽  
K. Van Leeuwen ◽  
K. Verschueren ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Linear Regression Analysis ◽  
Depression Scale ◽  
Well Being ◽  
Epidemiologic Studies ◽  
Depression Score ◽  
Perceived Parenting ◽  
Competing Interest ◽  
Over Time

IntroductionAdolescents’ well being is affected by their parenting situation and can influence their well being over time. We present an exploratory study with an Illumina 450 k array, comparing methylation in adolescents, based on perceived parenting at T0, and how methylation can interact with parenting in explaining depressive symptoms two years later (T2).ObjectivesIdentify differentially methylated regions (DMRs) associated with perceived parenting at T0 and investigate their association with depressive symptoms two years later.AimsAn exploratory analysis evaluating the association between methylation and depressive symptoms longitudinally.MethodsFrom two extreme parenting clusters: perceived supportive, and punishing neglecting, we randomly selected 44 adolescents (MAge = 14 at T0; 48%boys). The CES-D scale (Center for Epidemiologic Studies Depression Scale) assessed depressive symptoms. DMRs were identified based on the parenting clusters (DMRcate and comb-p) using llumina Infinium HumanMethylation 450 BeadChip data. Associations between the most significant CpG for each DMR and the depression score at T2, were calculated using linear regression analysis.ResultsWe identified 17 DMRs, but only cg13306335 in PEX10 was associated with depressive symptoms at T2 (P = 0.0014, Bonferroni (17 tests): P < 0.0029). Additionally, an interaction between parenting at T0 and PEX10 methylation (T0) in explaining depressive symptoms (T2) can be suggested (P = 0.014).ConclusionsWe show that methylation at PEX10's most significant CpG is correlated with depressive symptoms at T2, these exploratory results also suggest a possible interaction between parenting and PEX10 methylation at T0 in association with depressive symptoms at T2. Validation in a larger sample is needed to support the role of methylation and its interactions in depression over time.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals The Other Student Debt Crisis: How Borrowing to Pay for a Child’s College Education Relates to Parents’ Mental Health at Midlife

2019 ◽  
Vol 75 (7) ◽  
pp. 1494-1503
Author(s):  
Katrina M Walsemann ◽  
Jennifer A Ailshire ◽  
Caroline Sten Hartnett
Keyword(s):  
Mental Health ◽  
Depressive Symptoms ◽  
Debt Crisis ◽  
Short Form ◽  
Depression Scale ◽  
College Education ◽  
Epidemiologic Studies ◽  
Student Debt ◽  
Educational Debt ◽  
Nationally Representative

Abstract Objectives More parents are borrowing to help their children pay for college. These loans may be a source of financial stress and worry, which could influence parents’ mental health. We determine whether child-related educational debt is associated with worse mental health among parents and if fathers are more sensitive to this debt than mothers, given potential gender differences in financial decision-making and relationships with adult children. Method Data come from the National Longitudinal Survey of Youth 1979, a nationally representative sample of persons born between 1957 and 1964. We used the Center for Epidemiologic Studies Depression Scale and the Short Form-12 Mental Health Component Score to assess mental health. We restricted our sample to parents who had at least one biological child attend college and who were interviewed at age 50, when mental health was assessed (n = 3,545). Results Among fathers, having any child-related educational debt versus none was associated with fewer depressive symptoms, but having greater amounts of child-related educational debt was associated with more depressive symptoms and worse mental health. No relationship was found for mothers. Discussion Our findings indicate that the student debt crisis may also have mental health implications for aging parents, particularly for fathers.

scholarly journals Change in serum 25-hydroxyvitamin D and parallel change in depressive symptoms in Dutch older adults

2018 ◽  
Vol 179 (4) ◽  
pp. 239-249 ◽  
Author(s):  
Liset E M Elstgeest ◽  
Elisa J de Koning ◽  
Ingeborg A Brouwer ◽  
Natasja M van Schoor ◽  
Brenda W J H Penninx ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Depression Scale ◽  
Population Based ◽  
Epidemiologic Studies ◽  
Time Points ◽  
Hydroxyvitamin D ◽  
Parallel Change ◽  
Lower Baseline ◽  
25 Hydroxyvitamin D

Objective Previous prospective studies on the association between vitamin D status and depression used a single 25-hydroxyvitamin D (25(OH)D) measurement. We investigated the association between change in serum 25(OH)D and parallel change in depressive symptoms over time in Dutch older adults. Design A population-based, prospective study in two cohorts of older men and women from the Longitudinal Aging Study Amsterdam. Methods Serum 25(OH)D concentrations were determined at two time points: in 1995/1996 and 13 years later in the older cohort (aged 65–88y, n = 173) and in 2002/2003 and 6 years later in the younger cohort (55–65 years, n = 450). At these time points, depressive symptoms were measured with the Center for Epidemiologic Studies Depression scale (CES-D). Associations were tested by multiple linear regression analyses. Results During follow-up, serum 25(OH)D concentrations increased in 32.4% of the older cohort and in 69.8% of the younger cohort. In the older cohort, change in 25(OH)D was not associated with change in CES-D score. In the younger cohort, no associations were observed in participants with higher baseline 25(OH)D concentrations (>58.6 nmol/L), but in those with lower baseline 25(OH)D concentrations, an increase in 25(OH)D was associated with a decrease in CES-D score (adjusted B per 10 nmol/L 25(OH)D increase: −0.62 (95% CI: −1.17, −0.07)). Conclusions Our study suggests that over 6 years, an increase in serum 25(OH)D is associated with a small decrease in depressive symptoms in young older adults with lower baseline 25(OH)D. Well-designed intervention trials are required to determine causality.

scholarly journals The mediating role of adolescents’ loneliness and social withdrawal in the association between maternal depressive symptoms and suicidality in adolescence: A 20-year population-based study

2021 ◽  
pp. 1-9
Author(s):  
Lamprini Psychogiou ◽  
Marilyn N. Ahun ◽  
Michel Boivin ◽  
Richard E. Tremblay ◽  
Massimiliano Orri ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Indirect Effect ◽  
Social Withdrawal ◽  
Depression Scale ◽  
Population Based ◽  
Epidemiologic Studies ◽  
Maternal Depressive Symptoms ◽  
Mediating Role ◽  
Increased Risk ◽  
Development Data

Abstract We examined whether adolescents’ loneliness and social withdrawal mediated the association between maternal depressive symptoms and adolescent suicidality. Secondary analyses on the Québec Longitudinal Study of Child Development data were conducted (n = 1,623). Each mother completed the Centre for Epidemiologic Studies Depression Scale (at child ages 5 months, 1.5, 3.5, 5, and 7 years). Adolescent's social withdrawal (adolescent, father, and teacher reported at 10, 12, and 13 years) and loneliness (adolescent reported at 10, 12, and 13 years), were assessed using items from the Social Behavior Questionnaire and the Loneliness and Social Satisfaction Questionnaire, respectively. Adolescents completed self-reports to assess suicidal thoughts and attempts at 13, 15, 17, and 20 years. Children of mothers with higher levels of maternal depressive symptoms had an increased risk for suicidality (OR = 1.15, 95% CI: 1.03–1.28). Loneliness explained 16% of the total effect of maternal depressive symptoms on adolescent suicidality (indirect effect OR = 1.02, 95% CI: 1.00–1.04). There was no indirect effect of maternal depressive symptoms on adolescent suicidal outcomes via social withdrawal (indirect effect OR = 1.00, 95% CI: 0.99–1.02). Interventions that target loneliness may be beneficial for decreasing the risk for suicidality among adolescents of mothers with depressive symptoms.

scholarly journals Quality of Life in Transitioned Trans Persons: A Retrospective Cross-Sectional Cohort Study

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Lena Jellestad ◽  
Tiziana Jäggi ◽  
Salvatore Corbisiero ◽  
Dirk J. Schaefer ◽  
Josef Jenewein ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Short Form ◽  
Depression Scale ◽  
Transition Process ◽  
Epidemiologic Studies ◽  
Mental Wellbeing ◽  
Cross Sectional ◽  
Trans People

Background. Medical gender-affirming interventions (GAI) are important in the transition process of many trans persons. The aim of this study was to examine the associations between GAI and quality of life (QoL) of transitioned trans individuals. Methods. 143 trans persons were recruited from a multicenter outpatient Swiss population as well as a web-based survey. The QoL was assessed using the Short Form (36) Health Survey questionnaire (SF-36). Depressive symptoms were examined using the Short Form of the Center for Epidemiologic Studies-Depression Scale (ADS-K). Multiple interferential analyses and a regression analysis were performed. Results. Both transfeminine and transmasculine individuals reported a lower QoL compared to the general population. Within the trans group, nonbinary individuals showed the lowest QoL scores and significantly more depressive symptoms. A detailed analysis identified sociodemographic and transition-specific influencing factors. Conclusions. Medical GAI are associated with better mental wellbeing but even after successful medical transition, trans people remain a population at risk for low QoL and mental health, and the nonbinary group shows the greatest vulnerability.

scholarly journals Economic inequality and depressive symptoms: an individual versus aggregate-level analysis using Mexican survey data

2021 ◽  
pp. jech-2020-214682
Author(s):  
Lucio Esposito ◽  
Adrián Villaseñor ◽  
Rowena Jacobs
Keyword(s):  
Mental Health ◽  
Depressive Symptoms ◽  
Relative Deprivation ◽  
Multilevel Models ◽  
Economic Status ◽  
Empirical Studies ◽  
Economic Inequality ◽  
Depression Scale ◽  
Epidemiologic Studies ◽  
The Individual

BackgroundThere is a lack of consensus on the relationship between economic inequality and mental health, which may be due to the measures of inequality used in empirical studies. We studied this relationship using individual and aggregate measures of economic inequality, and tested whether there is an interaction between the individual and the aggregate levels.MethodsWe used data from a nationally representative Mexican health survey (Encuesta Nacional de Salud y Nutrición, n=44 324) where depressive symptoms were measured through a validated 7-item version of the Centre for Epidemiologic Studies Depression Scale. We estimated multilevel models employing aggregate inequality measures (Gini coefficient) and the individual-level framework of advantageous and disadvantageous inequality, where economic status comprised absolute wealth, relative deprivation and relative affluence.ResultsThe three facets of economic status were independently associated with depressive symptoms, while Gini coefficients showed no associations. Absolute wealth and relative affluence were associated with lower depressive symptoms while relative deprivation was associated with higher depressive symptoms. However, interaction models indicated an interplay between the Gini and relative affluence: higher status became a risk factor at high levels of aggregate economic inequality. For those at the top of the economic hierarchy, being in a context of high inequality more than doubles our measure of depressive symptoms—from 2.08 (95% CI 1.28 to 2.87) to 6.29 (95% CI 4.1 to 8.5) for state inequality and from 2.40 (95% CI 1.64 to 3.16) to 6.24 (95% CI 3.87 to 8.62) for municipal inequality.ConclusionWe provided a novel perspective on the economic gradient in mental health, and on how high aggregate economic inequality may harm also the better off. Policymakers need to consider the consequences of economic inequalities, which can harm the mental health of both those at the bottom and the top of the socioeconomic ladder.

Center for Epidemiologic Studies Depression Scale - Short Form

2006 ◽  
Author(s):  
Matthew P. Martens ◽  
Jerry C. Parker ◽  
Karen L. Smarr ◽  
James E. James E. Hewett ◽  
Bin Ge ◽  
...  
Keyword(s):  
Short Form ◽  
Depression Scale ◽  
Epidemiologic Studies
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