Health Effects of Migration: U.S. Chinese in and outside the Chinatown

1987 ◽  
Vol 21 (3) ◽  
pp. 555-576 ◽  
Author(s):  
Haitung King ◽  
Frances B. Locke
Keyword(s):  
Health Effects ◽  
San Francisco ◽  
Health Risks ◽  
Chinese Population ◽  
Statistical Significance ◽  
Socioeconomic Characteristics ◽  
Study Results ◽  
Causes Of Deaths ◽  
Two Populations ◽  
The U.S

Previous studies on health effects of migration at the international level have seldom been directed to those concentrated in segregated enclaves. This study hypothesizes that in spite of the known deviations in certain demographic and socioeconomic characteristics of Chinatown (San Francisco-N.Y.C.) residents from the U.S. Chinese population, no consistent relationship seems to exist between these attributes and health risks, as reflected in the mortality levels of the two populations. A convergence in mortality was observed for a noticeable number of causes of deaths, with but a few disease-cause sets of non-convergence with statistical significance. The study results were interpreted in terms of varying degree of acculturation experience.

scholarly journals Study protocol for a randomised controlled trial examining the effect of blood and plasma donation on serum perfluoroalkyl and polyfluoroalkyl substance (PFAS) levels in firefighters

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e044833
Author(s):  
Gabriel Silver ◽  
Yordanka Krastev ◽  
Miriam K Forbes ◽  
Brenton Hamdorf ◽  
Barry Lewis ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Health Effects ◽  
Whole Blood ◽  
Sulfonic Acid ◽  
Controlled Trial ◽  
Adverse Health Effects ◽  
Plasma Donation ◽  
Adverse Health ◽  
Study Results ◽  
Randomised Controlled

IntroductionPerfluoroalkyl and polyfluoroalkyl substances (PFAS) are a diverse group of compounds that have been used in hundreds of industrial applications and consumer products including aqueous film-forming foam (AFFF) for many years. Multiple national and international health and environmental agencies have accepted that PFAS exposures are associated with numerous adverse health effects. Australian firefighters have been shown to have elevated levels of PFAS in their blood, specifically perfluorooctane sulfonic acid (PFOS) and perfluorohexane sulfonic acid (PFHxS), due to the historical use of AFFF. While PFAS concentrations decline over time once the source of exposure has been removed, their potential adverse health effects are such that it would be prudent to develop an intervention to lower levels at a faster rate than occurs via natural elimination rates.Methods and analysisThis is a randomised controlled trial of current and former Australian firefighters in the Metropolitan Fire Brigade/Fire Rescue Victoria, and contractors, with previous occupational exposure to PFAS and baseline elevated PFOS levels. The study is investigating whether whole blood donation every 12 weeks or plasma donation every 6 weeks will significantly reduce PFAS levels, compared with a control group. We have used covariate-adaptive randomisation to balance participants’ sex and blood PFAS levels between the three groups and would consider a 25% reduction in serum PFOS and PFHxS levels to be potentially clinically significant after 12 months of whole blood or plasma donation. A secondary analysis of health biomarkers is being made of changes between screening and week 52 in all three groups.Ethics and disseminationThis trial has been approved by Macquarie University Human Research Ethics Committee (reference number: 3855), final protocol V.2 dated 12 June 2019. Study results will be disseminated via peer-reviewed publications and presentations at conferences.Trial registration numberAustralian New Zealand Clinical Trials Registry (ACTRN12619000204145).

scholarly journals Linkage Disequilibrium in Domestic Sheep

Genetics ◽  
2002 ◽  
Vol 160 (3) ◽  
pp. 1113-1122
Author(s):  
A F McRae ◽  
J C McEwan ◽  
K G Dodds ◽  
T Wilson ◽  
A M Crawford ◽  
...  
Keyword(s):  
Linkage Disequilibrium ◽  
Type I Error ◽  
Statistical Significance ◽  
Domestic Sheep ◽  
Type I ◽  
Single Nucleotide ◽  
Microsatellite Genotype ◽  
Marker Distance ◽  
The Relationship ◽  
Two Populations

Abstract The last decade has seen a dramatic increase in the number of livestock QTL mapping studies. The next challenge awaiting livestock geneticists is to determine the actual genes responsible for variation of economically important traits. With the advent of high density single nucleotide polymorphism (SNP) maps, it may be possible to fine map genes by exploiting linkage disequilibrium between genes of interest and adjacent markers. However, the extent of linkage disequilibrium (LD) is generally unknown for livestock populations. In this article microsatellite genotype data are used to assess the extent of LD in two populations of domestic sheep. High levels of LD were found to extend for tens of centimorgans and declined as a function of marker distance. However, LD was also frequently observed between unlinked markers. The prospects for LD mapping in livestock appear encouraging provided that type I error can be minimized. Properties of the multiallelic LD coefficient D′ were also explored. D′ was found to be significantly related to marker heterozygosity, although the relationship did not appear to unduly influence the overall conclusions. Of potentially greater concern was the observation that D′ may be skewed when rare alleles are present. It is recommended that the statistical significance of LD is used in conjunction with coefficients such as D′ to determine the true extent of LD.

scholarly journals Relationship of mammographic densities to breast cancer risk

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Engy A. Ali ◽  
Mariam Raafat
Keyword(s):  
Breast Cancer ◽  
Breast Density ◽  
Statistical Significance ◽  
Significant Risk ◽  
Close Relation ◽  
Mammographic Screening ◽  
Mammographic Breast Density ◽  
Study Results ◽  
Relationship Of ◽  
Mammographic Densities

Abstract Background Our goal was to find out the relation between mammographic densities and cancer of the breast according to the recent ACR classification. From the medical records of Kasereliny Hospital, 49,409 women were subjected to digital mammography for screening, of which 1500 breast cancer cases were collected. The mammographic categories of breast density were ACR-A, B, C, and D, which were detected by two senior radiologists. All radiological classifications were made using both standard mammographic views bilaterally. Two-sided tests of statistical significance were represented by all the P values. Results From 2014 to 2019, 49,409 women came for digital mammographic screening, their age ranges between 40 and 65, and all of them are included in the study. One thousand cases of breast cancer cases were radiologically and pathologically diagnosed. Different densities were arranged in descending pattern depending on the frequency of positive cases: D (13.7%), C (3.3%), B (2.7%), A (2.2%). There is positive significant risk ratio among every higher mammographic density in comparison to the lower density. Conclusion Our study results show that the risk of breast cancer is in close relation to the mammographic breast density.

Crustal structure southwest of the San Andreas fault from quarry blasts

1964 ◽  
Vol 54 (1) ◽  
pp. 67-77
Author(s):  
Robert M. Hamilton ◽  
Alan Ryall ◽  
Eduard Berg
Keyword(s):  
San Francisco ◽  
Crustal Structure ◽  
San Andreas Fault ◽  
P Wave ◽  
Geological Survey ◽  
San Andreas ◽  
Crustal Model ◽  
Crystalline Crust ◽  
The U.S

abstract To determine a crustal model for the southwest side of the San Andreas fault, six large quarry blasts near Salinas, California, were recorded at 27 seismographic stations in the region around Salinas, and along a line northwest of the quarry toward San Francisco. Data from these explosions are compared with results of explosion-seismic studies carried out by the U.S. Geological Survey on a profile along the coast of California from San Francisco to Camp Roberts. The velocity of Pg, the P wave refracted through the crystalline crust, in the Salinas region is 6.2 km/sec and the velocity of Pn is about 8.0 km/sec. Velocities of the direct P wave in near-sur-face rocks vary from one place to another, and appear to correlate well with gross geologic features. The thickness of the crust in the region southwest of the San Andreas fault from Salinas to San Francisco is about 22 kilometers.

The Misinterpretation of Study Results Based on Statistical Significance

Epidemiology ◽  
1999 ◽  
Vol 10 (4) ◽  
pp. 469 ◽  
Author(s):  
Andreas Stang ◽  
Karl-Heinz Jöckel ◽  
Gerasimos Anastassiou ◽  
Norbert Bornfeld
Keyword(s):  
Statistical Significance ◽  
Study Results

scholarly journals The health effects of quarantine during the COVID-19 pandemic

Work ◽  
2020 ◽  
Vol 67 (3) ◽  
pp. 523-527
Author(s):  
Maryam Feiz Arefi ◽  
Amin Babaei-Pouya ◽  
Mohsen Poursadeqiyan
Keyword(s):  
Health Effects ◽  
World Health ◽  
Economic Activities ◽  
Negative Effects ◽  
Social Hygiene ◽  
Social Communications ◽  
Study Results ◽  
Control And Prevention ◽  
Health Organization ◽  
Made In

BACKGROUND: Quarantine is considered as an effective solution in the early stages of an epidemic. In the case of the coronavirus epidemic, quarantine was also recommended and implemented as a significant guideline to prevent the disease. However, despite the benefits of quarantine, there are also complications and problems. OBJECTIVE: The present study aimed to investigate the health effects of quarantine during the COVID-19 pandemic. METHODS: This study was conducted as a literature review through searching the databases Google Scholar, PubMed, and Science Direct for papers published before July 2020. The research was conducted based on the keywords “Coronavirus,” “COVID-19,” and “quarantine.” The references of the papers were also reviewed to find the ones not found in the databases. The guidelines published by reputable organizations such as the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) were used in this study. RESULTS: Although quarantine is applied as an important and primary solution in the outbreak of epidemics, in cases of pandemics, it may not be free of negative effects on individuals and public health. However, because of the need to reopen and restart social and economic activities, some changes should be made in lifestyles and work activities. Using cyberspace and telework can be helpful. As the findings showed, COVID-19 bubbles can be used to restore social communications. CONCLUSION: Using masks, avoiding unnecessary gatherings, complying with personal and social hygiene, and respecting social distancing can be valuable solutions that, if implemented properly, can decrease the rate of the disease significantly. It is also emphasized that quarantine is still necessary and important as the best solution for sick people and individuals who are suspected carriers of the disease.

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