Aerobic interval training increases peak oxygen uptake more than usual care exercise training in myocardial infarction patients: a randomized controlled study

2011 ◽  
Vol 26 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Trine Moholdt ◽  
Inger Lise Aamot ◽  
Ingrid Granøien ◽  
Lisbeth Gjerde ◽  
Gitte Myklebust ◽  
...  
Keyword(s):  
Heart Rate ◽  
Exercise Training ◽  
Oxygen Uptake ◽  
Usual Care ◽  
Interval Training ◽  
Peak Oxygen Uptake ◽  
Peak Heart Rate ◽  
Randomized Controlled ◽  
Aerobic Interval Training

Objective: Exercise capacity strongly predicts survival and aerobic interval training (AIT) increases peak oxygen uptake effectively in cardiac patients. Usual care in Norway provides exercise training at the hospitals following myocardial infarction (MI), but the effect and actual intensity of these rehabilitation programmes are unknown. Design: Randomized controlled trial. Setting: Hospital cardiac rehabilitation. Subjects: One hundred and seven patients, recruited two to 12 weeks after MI, were randomized to usual care rehabilitation or treadmill AIT. Interventions: Usual care aerobic group exercise training or treadmill AIT as 4 × 4 minutes intervals at 85–95% of peak heart rate. Twice weekly exercise training for 12 weeks. Main measures: The primary outcome measure was peak oxygen uptake. Secondary outcome measures were endothelial function, blood markers of cardiovascular disease, quality of life, resting heart rate, and heart rate recovery. Results: Eighty-nine patients (74 men, 15 women, 57.4 ± 9.5 years) completed the programme. Peak oxygen uptake increased more ( P = 0.002) after AIT (from 31.6 ± 5.8 to 36.2 ± 8.6 mL·kg−1·min−1, P < 0.001) than after usual care rehabilitation (from 32.2 ± 6.7 to 34.7 ± 7.9 mL·kg−1·min−1, P < 0.001). The AIT group exercised with significantly higher intensity in the intervals compared to the highest intensity in the usual care group (87.3 ± 3.9% versus 78.7 ± 7.2% of peak heart rate, respectively, P < 0.001). Both programmes increased endothelial function, serum adiponectin, and quality of life, and reduced serum ferritin and resting heart rate. High-density lipoprotein cholesterol increased only after AIT. Conclusions: AIT increased peak oxygen uptake more than the usual care rehabilitation provided to MI patients by Norwegian hospitals.

Comparative efficiency of continuous trainings and aerobic interval training in patients after myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
Y Dovgalyuk ◽  
Y.U.V Chistyakova ◽  
L.L Jarchenkova ◽  
S.O Fokicheva ◽  
A.A Zolotareva ◽  
...  
Keyword(s):  
Heart Rate ◽  
Oxygen Uptake ◽  
Physical Training ◽  
Interval Training ◽  
Primary Angioplasty ◽  
Peak Oxygen Uptake ◽  
Maximal Heart Rate ◽  
Aerobic Interval Training ◽  
Medical Academy ◽  
State Medical Academy

Abstract Background The basis of cardiac rehabilitation programs (CRP) is aerobic physical training, which improves exercise capacity in patients with an acute myocardial infarction (MI) after primary angioplasty of the infarct-related vessel. However, which type - aerobic interval training (AIT) or aerobic continuous trainings (ACT) are most effective for improving peak oxygen uptake (VO2 max) remains unclear and controversial. Purpose To evaluate the effects of CRP, including AIT or ACT, on exercise capacity and lung function in patients with MI after primary angioplasty of the infarct-related vessel. Methods Seventy MI patients (58 men and 12 women, mean age – 59,2±8,0 years) were undergone the three-week CRP in the Ivanovo State Medical Academy Clinic. The CRP for all patients included: daily controlled physical training on the Bicycle Ergometer and Treadmill, group exercises in therapeutic gymnastics, dosed walking and walking on the stairs with an individually calculated pace. Depending on the mode of physical training all patients were randomized of five weekly sessions in to two groups, comparable in age and gender: AIT group (35 patients) and ACT group (35 patients). The ACT group was training at 50–60% of peak heart rate. The AIT group protocol consisted of ten 1-min intervals at 85–90% of maximal heart rate separated by ten 1-min active recovery periods of moderate intensity at 40–60% of the maximal heart rate. Changes in 6-min walk distance test (6MWT), peak oxygen uptake (VO2max), relative load power, total lung capacity (TLC) and forced expiratory volume in one second (FEV1) before and after CRP were investigated. Data are presented as a median (interquartile ratio [Q1; Q3]). Results After finishing CRP 6MWT distance increased in both groups, but was higher in AIT group 492 [460–510] m compared to the ACT group – 465 [424–510] m (p&lt;0.05). Peak oxygen uptake increased more (p&lt;0.05) after AIT: from 16.8 [15.3–19.8] to 20.7 [16.5–21.9] ml kg–1 min–1 (p&lt;0.05), than after ACT – from 15.8 [14.7–18.6] to 16.1 [15.8–20.5] ml kg–1 min–1 (p&gt;0.05). At the end of the CRP relative load power during cardiopulmonary exercise test was higher in AIT group compared to the ACT group: 1.5 [1.3–1.7] vs 1.2 [1.0–1.5] Wt/kg respectively (p&lt;0.05). In the AIT group TLC increased significantly from 3.13 [2.63–4.05] to 4.14 [3.91–4.87] L (p&lt;0.05) then in ACT group: from 3.19 [2.82–3.74] to 3.21 [3.03–3.57] L (p&gt;0.05). FEV1 had no changes in both groups. Both programs reduced anxiety and depression, systolic and diastolic blood pressure and increased quality of life. Conclusion AIT as compared to ACT provided a more pronounced training effect on the cardiorespiratory system due to high-intensity loading phases. Therefore, AIT is more preferable in cardiac rehabilitation of patients with MI after primary angioplasty of the infarct-related vessel. Funding Acknowledgement Type of funding source: Public Institution(s). Main funding source(s): Ivanovo State Medical Academy

Controlled study of myocardial recovery after interval training in heart failure: SMARTEX-HF – rationale and design

2011 ◽  
Vol 19 (4) ◽  
pp. 813-821 ◽  
Author(s):  
Asbjørn Støylen ◽  
Viviane Conraads ◽  
Martin Halle ◽  
Axel Linke ◽  
Eva Prescott ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Exercise Training ◽  
Oxygen Uptake ◽  
Primary Endpoint ◽  
Interval Training ◽  
Peak Oxygen Uptake ◽  
Left Ventricular ◽  
Regular Exercise

Background: The large randomized controlled multicentre clinical trial, HF-ACTION, recently demonstrated that a programme of recommendation of regular exercise training at moderate intensity is safe, improves quality of life, and reduces the combined endpoint of all-cause death and hospitalization in patients with chronic heart failure. However, the size of beneficial effects was modest compared to results published in smaller single studies and meta-analyses. Objective: Based on results of a pilot study, the objective of the present investigation is to test the hypothesis that a programme comprising interval training at high relative intensity would yield significantly larger effects in terms of left ventricular remodelling compared to moderate continuous exercise training. Study design: In a three-armed randomized multicentre study of stable heart failure patients with left ventricular ejection fraction ≤35%, the effects of a 12-week programme of high-intensity interval training (HIT; 85–90% of peak oxygen uptake, VO2peak) will be compared to actual practice in Europe, represented by either an isocaloric programme of moderate continuous training (MCT; 50–60% of VO2peak) and a recommendation of regular exercise (RE) of the individual patients’ own preference based on clinical practice at the local centre. The primary endpoint is reverse remodelling, defined as change in left ventricular end-diastolic diameter assessed by echocardiography. Secondary endpoints include peak oxygen uptake (VO2peak), biomarkers, quality of life, and level of physical activity assessed by questionnaires. In addition, long-term maintenance of effects after the supervised training period will be determined. Assessments will be made at baseline, after the 12-week intervention programme, and at 1-year follow up. A total number of 200 patients on treatment per protocol, randomized to the three groups in a 1 : 1 : 1 manner, is estimated to detect clinically relevant differences in effect with HIT vs. MCT and RE ( p < 0.05; statistical power 0.90) for the primary endpoint. Inclusion of patients started May 2009 and will run until total number has been reached.

Verification phase as a useful tool in the determination of the maximal oxygen uptake of distance runners

2006 ◽  
Vol 31 (5) ◽  
pp. 541-548 ◽  
Author(s):  
Adrian W. Midgley ◽  
Lars R. McNaughton ◽  
Sean Carroll
Keyword(s):  
Heart Rate ◽  
Oxygen Uptake ◽  
Maximal Oxygen Uptake ◽  
Peak Oxygen Uptake ◽  
Treadmill Running ◽  
Distance Runners ◽  
Peak Heart Rate ◽  
Incremental Test ◽  
Volitional Exhaustion

This study investigated the utility of a verification phase for increasing confidence that a “true” maximal oxygen uptake had been elicited in 16 male distance runners (mean age (±SD), 38.7  (± 7.5 y)) during an incremental treadmill running test continued to volitional exhaustion. After the incremental test subjects performed a 10 min recovery walk and a verification phase performed to volitional exhaustion at a running speed 0.5 km·h–1 higher than that attained during the last completed stage of the incremental phase. Verification criteria were a verification phase peak oxygen uptake ≤ 2% higher than the incremental phase value and peak heart rate values within 2 beats·min–1 of each other. Of the 32 tests, 26 satisfied the oxygen uptake verification criterion and 23 satisfied the heart rate verification criterion. Peak heart rate was lower (p = 0.001) during the verification phase than during the incremental phase, suggesting that the verification protocol was inadequate in eliciting maximal values in some runners. This was further supported by the fact that 7 tests exhibited peak oxygen uptake values over 100 mL·min–1 (≥ 3%) lower than the peak values attained in the incremental phase. Further research is required to improve the verification procedure before its utility can be confirmed.

scholarly journals Physical exercise training in patients with a Fontan circulation: A systematic review

2020 ◽  
pp. 204748732094286
Author(s):  
Linda E Scheffers ◽  
Linda EM vd Berg ◽  
Gamida Ismailova ◽  
Karolijn Dulfer ◽  
Johanna JM Takkenberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Exercise Training ◽  
Oxygen Uptake ◽  
Cardiac Function ◽  
Exercise Capacity ◽  
Peak Oxygen Uptake ◽  
Training Intervention ◽  
Fontan Patients

Background Patients with a Fontan circulation have a reduced exercise capacity, which is an important prognostic predictor of morbidity and mortality. A way to increase exercise capacity in Fontan patients might be exercise training. This systematic review assesses the effects of exercise training investigated in Fontan patients in order to provide an overview of current insights. Design and methods Studies evaluating an exercise training intervention in Fontan patients published up to February 2020 were included in this systematic review. Results From 3000 potential studies, 16 studies reported in 22 publications met the inclusion criteria. In total, 264 Fontan patients with mean age range 8.7–31 years, were included. Different training types including inspiratory muscle training, resistance training and aerobic training were investigated. Main outcome measures reported were peak oxygen uptake, cardiac function, lung function, physical activity levels and quality of life. Peak oxygen uptake increased significantly in 56% of the studies after training with an overall mean increase of +1.72 ml/kg/min (+6.3%). None of the studies reported negative outcome measures related to the exercise programme. In four studies an adverse event was reported, most likely unrelated to the training intervention. Conclusions Exercise training in Fontan patients is most likely safe and has positive effects on exercise capacity, cardiac function and quality of life. Therefore exercise training in Fontan patients should be encouraged. Further studies are required to assess the optimal training type, intensity, duration and long-term effects.

scholarly journals Prehabilitation Programs for Cancer Patients: a Systematic Review of Randomized-controlled Trials

2021 ◽  
Author(s):  
Jose F Meneses-Echavez ◽  
Andrés F. Loaiza-Betancur ◽  
Víctor Díaz-López ◽  
Andrés M. Echavarría-Rodríguez ◽  
Hector R Triana-R
Keyword(s):  
Systematic Review ◽  
Exercise Training ◽  
Randomized Controlled Trials ◽  
Usual Care ◽  
Cancer Patients ◽  
The Body ◽  
Controlled Trials ◽  
Promising Alternative ◽  
Randomized Controlled

Abstract Background: Prehabilitation programs focusing on exercise training as the main component are known as a promising alternative for improving patients’ outcomes before surgical treatment of different cancers. This systematic review aimed to determine the effects of prehabilitation programs compared with usual care for cancer patients.Methods/design: We searched CENTRAL, MEDLINE, and EMBASE from inception to 2020, and hand-searched clinical trial registries. We included randomized controlled trials (RCTs) in adults, survivors of any type of cancer, that compared prehabilitation programs focusing on exercise training as the major component with usual care or other active interventions. Outcome measures were health-related quality of life (HRQL), muscular strength, postoperative complications, average length of stay (ALOS), handgrip strength, and physical activity levels. Two reviewers independently selected the studies, extracted data, assessed the risk of bias and the quality of evidence using the GRADE approach.Results: 14 RCTs published between 2010-2020 met our inclusion criteria (n=1044 participants). Colorectal and lung cancers were the most common diagnoses with 5 studies (36%) each. The studies showed concerns regarding outcome measurement, selective reporting, and attrition. Four comparisons were identified: combined training vs rehabilitation/usual care; high-intensity interval training vs usual care; respiratory muscle training plus aerobic training vs usual care, and pelvic floor training vs usual care. The studies provided no clear evidence of an effect between groups. We assessed the certainty of the body of evidence as very low, downgraded due to serious study limitations and imprecision.Conclusion: It is uncertain whether prehabilitation programs compared with usual care have an effect in cancer patients. We have very little confidence in the results and the true effect is likely to be substantially different from these. Further research is needed before we could draw a more certain conclusion.Systematic review registration: CRD42019125658

scholarly journals Comparison of Acute Responses to Two Different Cycling Sprint Interval Exercise Protocols with Different Recovery Durations

2020 ◽  
Vol 17 (3) ◽  
pp. 1026 ◽  
Author(s):  
Natalia Danek ◽  
Marcin Smolarek ◽  
Kamil Michalik ◽  
Marek Zatoń
Keyword(s):  
Heart Rate ◽  
Oxygen Uptake ◽  
Perceived Exertion ◽  
Lactate Concentration ◽  
Peak Oxygen Uptake ◽  
Rating Of Perceived Exertion ◽  
Peak Power Output ◽  
Peak Heart Rate ◽  
Interval Exercise ◽  
Acute Responses

Background: Knowledge of acute responses to different sprint interval exercise (SIE) helps to implement new training programs. The aim of this study was to compare the acute physiological, metabolic and perceptual responses to two different SIE cycling protocols with different recovery durations. Methods: Twelve healthy, active male participants took part in this study and completed four testing sessions in the laboratory separated by a minimum of 72h. Two SIE protocols were applied in randomized order: SIE6×10”/4’—six “all-out” repeated 10-s bouts, interspersed with 4-min recovery; and SIESERIES—two series of three “all-out” repeated 10-s bouts, separated by 30-s recovery and 18-min recovery between series. Protocols were matched for the total work time (1 min) and recovery (20 min). Results: In SIESERIES, peak oxygen uptake and peak heart rate were significantly higher (p < 0.05), without differences in peak blood lactate concentration and mean rating of perceived exertion compared to SIE6×10”/4’. There were no differences in peak power output, peak oxygen uptake and peak heart rate between both series in SIESERIES. Conclusions: Two series composed of three 10-s “all-out” bouts in SIESERIES protocol evoked higher cardiorespiratory responses, which can provide higher stimulus to improve aerobic fitness in regular training.

scholarly journals Clinical Evaluation of Exercise Capacity in Adults with Systemic Right Ventricle

2019 ◽  
Vol 46 (1) ◽  
pp. 14-20 ◽  
Author(s):  
Beata Rog ◽  
Kinga Salapa ◽  
Magdalena Okolska ◽  
Natalia Dluzniewska ◽  
Piotr Werynski ◽  
...  
Keyword(s):  
Heart Rate ◽  
Oxygen Uptake ◽  
Right Ventricle ◽  
Peak Oxygen Uptake ◽  
Cardiopulmonary Exercise Test ◽  
Control Group ◽  
Test Results ◽  
Peak Heart Rate ◽  
Systemic Right Ventricle ◽  
Atrial Switch

The right ventricle provides systemic circulation in individuals with congenitally corrected transposition of the great arteries (CCTGA) and in those with complete transposition who have had an atrial switch repair (DTGA). The aim of this study was to evaluate how the systemic right ventricle adapts to increased workload and oxygen demand during exercise. From November 2005 through December 2015, 3,358 adult patients with congenital heart disease were treated at our institution; we identified 48 (26 females, 22 males; median age, 25.4 ± 8.1 yr) who met the study criteria; 37 had DTGA and atrial switch repair, and 11 had CCTGA. We studied their echocardiographic and cardiopulmonary exercise test results. A control group consisted of 29 healthy sex- and age-matched volunteers. On exercise testing, oxygen uptake at anaerobic threshold, peak oxygen uptake, peak heart rate, and percentage of maximal heart rate were significantly lower in the group with systemic right ventricle than in the control group (all P &lt;0.001); in contrast, the peak ventilatory equivalent for carbon dioxide was higher in the study group (P=0.013). Impaired systemic right ventricular function reduced peak oxygen uptake. The peak heart rate was lower in the CCTGA group than in the DTGA group. Our results indicate that reduced exercise capacity is related to impaired systemic right ventricular function, severe tricuspid valve regurgitation, and chronotropic incompetence. There was no correlation between cardiopulmonary exercise test results and time after surgery. Chronotropic efficiency is lower in individuals with CCTGA than in those with DTGA.

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