Effects of high-intensity interval training in a three-week cardiovascular rehabilitation: a randomized controlled trial

2020 ◽  
Vol 34 (5) ◽  
pp. 646-655
Author(s):  
Udo F Wehmeier ◽  
Alexander Schweitzer ◽  
Armin Jansen ◽  
Herbert Probst ◽  
Stephan Grüter ◽  
...  

Objective: The aim of this study was to assess the benefit of using high-intensity interval training for cardiovascular patients undergoing outpatient rehabilitation in a standard short-term (three-week) program in Germany. Design: This is a randomized controlled trial (RCT). Setting: This study was conducted at Cardiowell (Wuppertal, Germany), an outpatient rehabilitation center. Intervention: Patients underwent the typical three-week German outpatient rehabilitation program using either moderate continuous training (i.e. the standard training program) or high-intensity interval training. Main measures: A total of 50 patients of an outpatient rehabilitation center were randomized into two groups. The control group underwent the standard rehabilitation protocol that applied moderate continuous training, and the intervention group trained according to a high-intensity interval protocol. Patients trained on a bicycle ergometer. Peak power output, oxygen uptake parameters, heart frequencies, and blood pressure were compared at the beginning and at the end of the rehabilitation program. Results: After three weeks, the intervention group had improved to a significantly greater extent in maximal performance parameters than the control group: the peak power output (20.9 (±14.1) W; control 8.8 (±10.4) W), maximum oxygen uptake (0.33 (±0.33) L/min; control 0.05 (±0.29) L/min)), relative maximum oxygen uptake (3.4 (±4.2) mL/kg/min; control 0.9 (±3.1) mL/kg/min), and O2 pulse (1.8 (±2.2) mL/heart beat; control 0.35 (±1.7) mL/heart beat). Conclusion: The implementation of high-intensity interval training during a typical three-week German cardiac rehabilitation has the power to increase the outcome for the patients.

2002 ◽  
Vol 27 (4) ◽  
pp. 336-348 ◽  
Author(s):  
Paul B. Laursen ◽  
Michelle A. Blanchard ◽  
David G. Jenkins

This study examined the effects of four high-intensity interval-training (HIT) sessions performed over 2 weeks on peak volume of oxygen uptake [Formula: see text] the first and second ventilatory thresholds (VT1, VT2) and peak power output (PPO) in highly trained cyclists. Fourteen highly trained male cyclists [Formula: see text] performed a ramped cycle test to determine [Formula: see text]VT1, VT2, and PPO. Subjects were divided equally into a HIT group and a control group. The HIT group performed four HIT sessions (20 × 60 s at PPO, 120 s recovery); the [Formula: see text] test was repeated < 1 wk after the HIT program. Control subjects maintained their regular training program and were reassessed under the same timeline. There was no change in [Formula: see text] for either group; however, the HIT group showed a significantly greater increase in VT1 (+22% vs. −3%), VT2 (+15% vs. −1%), and PPO (+4.3 vs. −4%) compared to controls (all P < .05). This study has demonstrated that HIT can improve VT1, VT2 and PPO, following only four HIT sessions in already highly trained cyclists. Key words: cycling, cyclists, heart rate, oxygen uptake, short-term training, ventilatory threshold


2020 ◽  
Author(s):  
Angela S Lee ◽  
Nathan A Johnson ◽  
Margaret McGill ◽  
Jane Overland ◽  
Connie Luo ◽  
...  

<b>Objective:</b> To study the effect of 12 weeks of high-intensity interval training (HIIT) on glycemic control in adults with type 1 diabetes with overweight or obesity. <p> </p> <p><b>Research Design and Methods:</b> Thirty inactive adults with type 1 diabetes who had BMI≥25kg/m<sup>2</sup> and HbA1c≥7.5% were randomized to 12 weeks of either: HIIT exercise intervention consisting of 4x4 minutes HIIT (85-95% HRpeak) performed thrice weekly, or usual care control. In a partial cross-over design, the control group subsequently performed the 12-week HIIT intervention. The primary endpoint was the change in HbA1c from baseline to 12 weeks. Glycemic and cardiometabolic outcomes were measured at 0, 12, and 24 weeks.</p> <p> </p> <p><b>Results:</b> Participants were aged 44±10 years, with diabetes duration 19±11 years, and BMI 30.1±3.1 kg/m<sup>2</sup>.<sup> </sup>HbA1c decreased from 8.63 ± 0.66% at baseline to 8.10 ± 1.04% at 12 weeks in the HIIT intervention group (p=0.01), however this change was not significantly different to the control group (HIIT -0.53 ± 0.61%, control -0.14 ± 0.48%, p=0.08). In participants who undertook at least 50% of the prescribed HIIT intervention, the HbA1c reduction was significantly greater than control (HIIT -0.64 ± 0.64% (n=9), control -0.14 ± 0.48% (n=15), p=0.04). There were no differences in insulin dose, hypoglycemia on continuous glucose monitoring, blood pressure, blood lipids, body weight or body composition between groups. </p> <p> </p> <p><b>Conclusions:</b> <a>Overall, there was no significant reduction in HbA1c with a 12-week HIIT intervention in adults with type 1 diabetes. However glycaemic control may improve for people who undertake HIIT with greater adherence.</a></p>


Sports ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 92
Author(s):  
Timo Kirchenberger ◽  
Sascha Ketelhut ◽  
Reinhard G. Ketelhut

The effects of moderate-intensity continuous training (MICT) and a combination of MICT and high-intensity interval training (HIIT) on rowing performance and VO2peak were investigated in young athletes. Seventeen well-trained rowers (aged 15 ± 1.3 years) were randomly allocated to an intervention (IG) (n = 10) and control group (CG) (n = 7). During 8 weeks, both groups took part in the regular rowing training (3×/week MICT, 70–90 min, 65–70% of HRpeak + 2×/week resistance training). The IG completed an additional high-intensity interval training twice weekly (2 × 4 × 2 min at ≈95% of HRpeak, 60 s rest). Instead of the HIIT, the CG completed two more MICT sessions (70–90 min, 65–70% of HRpeak). Before and after the intervention, a 2000 m time trial and an exercise test were performed. The IG showed a significant improvement (p = 0.001) regarding the absolute rowing time in the graded exercise test. Furthermore, the intervention group showed a significant increase in relative VO2peak (p = 0.023), a significant increase in absolute VO2peak (p = 0.036), and a significant improvement in the 2000 m time trail (p = 0.003). No significant changes could be detected in the CG. The interaction effects were not significant. A mixed-intensity training, including HIIT, was beneficial on rowing performance and VO2peak in highly trained athletes.


BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e048281
Author(s):  
Iben Elmerdahl Rasmussen ◽  
Frederik Foged ◽  
Josephine Bjørn Budde ◽  
Rasmus Syberg Rasmussen ◽  
Villads Rasmussen ◽  
...  

IntroductionCOVID-19 is associated with a marked systemic inflammatory response with concomitant cardiac injury and remodelling, but it is currently unknown whether the latter is reversible. Given that high-intensity interval training (HIIT) is a powerful stimulus to improve cardiorespiratory fitness while also eliciting marked anti-inflammatory effects, it may be an important countermeasure of reducing cardiopulmonary morbidity following COVID-19.Methods and analysis40 COVID-19 survivors who have been discharged from hospital will be included in this investigator-blinded randomised study with a 12-week HIIT intervention. Patients will be 1:1 block-randomised by sex to either a supervised HIIT exercise group or standard care (control group). The main hypothesis is that a 12-week HIIT scheme is a safe way to improve loss of cardiac mass and associated cardiorespiratory fitness, despite hypothesised limited HIIT-induced changes in conventional lung function indices per se. Ultimately, we hypothesise that the HIIT scheme will reduce post-COVID-19 symptoms and improve quality of life.Ethics and disseminationThis study is approved by the Scientific Ethical Committee at the Capital Region of Denmark (H-20033733, including amendments 75068 and 75799) and registered at ClinicalTrials.gov (NCT04647734, pre-results). The findings will be published in a peer-reviewed journal, including cases of positive, negative and inconclusive results.Trial registration numberNCT04549337.


2017 ◽  
Vol 25 (2) ◽  
pp. 355-373 ◽  
Author(s):  
Alberto Ruiz-Ariza ◽  
Sara Suárez-Manzano ◽  
Sebastián López-Serrano ◽  
Emilio J Martínez-López

Evidence suggests that moderate physical activity (PA) positively relates to creativity and emotional intelligence (EI) in adolescents. However, it is unknown whether cooperative PA (physical exercises in pairs or small groups to enhance motivation, self-efficacy, and pro-social behaviours), performed over less time but at higher intensity, could have similar effects within a school setting. The aim was to analyse the effect of cooperative high-intensity interval training (C-HIIT) on creativity and EI in adolescents aged 12–16 years, and whether improvement effects are different according to weekly PA level. A randomised controlled trial was conducted with a control group (CG, n = 94), which did static stretching, and an experimental group (EG, n = 90), which performed C-HIIT. Both groups performed the activity during 16 minutes at the beginning of physical education (PE) classes. Creativity was assessed with one factor, and EI through four factors (well-being, self-control, emotionality, and sociability). Age and body mass index (BMI) were used as confounders. Both were measured twice (baseline and after 12 weeks). The EG increased well-being and sociability factors after the C-HIIT programme (both p < 0.001). More specifically, inactive adolescents in the EG showed significant improvements in comparison to the CG in creativity, well-being, and sociability ( p = 0.028, p < 0.001, and p < 0.003, respectively). However, we did not find changes among active adolescents. A programme of C-HIIT in PE is a novel strategy to improve creativity and EI, especially in physically inactive adolescents. Starting PE classes with 16 minutes of C-HIIT could be recommended, independently of other activities planned for the session.


2020 ◽  
Author(s):  
Angela S Lee ◽  
Nathan A Johnson ◽  
Margaret McGill ◽  
Jane Overland ◽  
Connie Luo ◽  
...  

<b>Objective:</b> To study the effect of 12 weeks of high-intensity interval training (HIIT) on glycemic control in adults with type 1 diabetes with overweight or obesity. <p> </p> <p><b>Research Design and Methods:</b> Thirty inactive adults with type 1 diabetes who had BMI≥25kg/m<sup>2</sup> and HbA1c≥7.5% were randomized to 12 weeks of either: HIIT exercise intervention consisting of 4x4 minutes HIIT (85-95% HRpeak) performed thrice weekly, or usual care control. In a partial cross-over design, the control group subsequently performed the 12-week HIIT intervention. The primary endpoint was the change in HbA1c from baseline to 12 weeks. Glycemic and cardiometabolic outcomes were measured at 0, 12, and 24 weeks.</p> <p> </p> <p><b>Results:</b> Participants were aged 44±10 years, with diabetes duration 19±11 years, and BMI 30.1±3.1 kg/m<sup>2</sup>.<sup> </sup>HbA1c decreased from 8.63 ± 0.66% at baseline to 8.10 ± 1.04% at 12 weeks in the HIIT intervention group (p=0.01), however this change was not significantly different to the control group (HIIT -0.53 ± 0.61%, control -0.14 ± 0.48%, p=0.08). In participants who undertook at least 50% of the prescribed HIIT intervention, the HbA1c reduction was significantly greater than control (HIIT -0.64 ± 0.64% (n=9), control -0.14 ± 0.48% (n=15), p=0.04). There were no differences in insulin dose, hypoglycemia on continuous glucose monitoring, blood pressure, blood lipids, body weight or body composition between groups. </p> <p> </p> <p><b>Conclusions:</b> <a>Overall, there was no significant reduction in HbA1c with a 12-week HIIT intervention in adults with type 1 diabetes. However glycaemic control may improve for people who undertake HIIT with greater adherence.</a></p>


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
Y.C Huang ◽  
J.S Wang

Abstract Background Interventricular interactions in increased RV afterload such as hypoxia stress, which affects both synchrony and function in an in-series effect as well as a parallel effect arising from leftward septal shift. Improved myocardial contractility is a critical circulatory adaptation to exercise training, however, the types of exercise that can improve interventricular synchrony under hypoxic environment have not yet been established. Purpose This study investigates how high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) influence on the interventricular synchrony in response to normobaric hypoxia in sedentary men. Methods Fifty-four sedentary males were randomized to perform HIIT (3-minute intervals at 40% and 80% VO2peak, n=18), MICT (sustained 60% VO2peak, n=18) for 30 minutes/day, 5 days/week for 6 weeks and the control group (CTL, n=18). Synchrony measurements at apical 4-chamber view including (1) intra-delay, the difference in time to peak strain (TS) between segmental septal-to-lateral ventricular or atrial walls, and (2) inter-delay, the difference in TS between RV or RA free wall and LV or LA lateral wall. The data were acquired by 2-dimensional speckle tracking echocardiography at rest under hypoxic condition (12% FIO2, simulated an altitude of 4,500 m) before and after the interventions. Results HIIT had significantly elevated radial and longitudinal strains in both LA and LV (p&lt;0.05). As the results showed, HIIT was superior than MICT in improvement of longitudinal intra-delay of LV; furthermore, only HIIT simultaneously ameliorated both radial and longitudinal synchrony at apex. Although the HIIT enhanced intraventricular synchrony in both motions, whereas the interventricular synchrony deteriorated at radial motion. In atrium synchrony, although both groups augmented the intra-LA synchrony, however, only HIIT reduced the inter-delay between LA and RA at the roof motion. LV end-systolic volume (ESV) significantly correlated with the longitudinal inter-delay of ventricle (r=−0.53, p&lt;0.05), whereas the LV end-diastolic volume (EDV) correlated with the inter-delay of atrium in roof motion (r=0.40, p&lt;0.05). Conclusion We found differences between HIIT and MICT in segmental intra- and inter- synchrony. HIIT enhanced both ventricular or atrial synchrony, and further increased the EDV coupled with decreased ESV. These findings give new insight into cardiac adaptation to difference endurance training and the long-term impact of such changes warrants future study in cardiac diseases. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): National Science Council of Taiwan


Author(s):  
Soo-Yong Park ◽  
Thomas Jürgen Klotzbier ◽  
Nadja Schott

The ability to process goal-related visual information while ignoring goal-irrelevant information is essential for the human attention system. The study aimed to investigate how perceptual–cognitive performance was affected during high-intensity interval training (HIIT) using a 3D-multiple object tracking (3D-MOT) task called Neurotracker (NT). In an experimental design, 42 healthy adults (age M = 23.3 SD = 2.94, VO2max 52.8 ± 5.66 mL·kg−1·min−1) were randomly assigned to an intervention (HIIT + NT, NT, HIIT) or control group. NT performance (20 trials per session) was measured pre-and post-test (at 5, 15, and 25 min while running on the treadmill). The participants trained twice a week for a 4-week intervention period. There was a significant interaction effect between pre/post-test and groups regarding perceptual-cognitive performance, indicating similar enhancements in the HIIT + NT and the NT group during exercise. HIIT influences physical fitness but did not show any impact on perceptual–cognitive performance. Due to the specific NT task characteristics, improved physical abilities may not directly impact sport-specific perceptual-cognitive performance. Our findings suggest that training resulted in substantial task-specific gains. Therefore, combination training may be proposed as a training program to improve perceptual–cognitive, and physical performance in a time-efficient way.


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