scholarly journals May the force be with you: Transfer of healthy mitochondria from stem cells to stroke cells

2018 ◽  
Vol 39 (2) ◽  
pp. 367-370 ◽  
Author(s):  
Cesar V Borlongan ◽  
Hung Nguyen ◽  
Trenton Lippert ◽  
Eleonora Russo ◽  
Julian Tuazon ◽  
...  
Keyword(s):  
United States ◽  
Stem Cells ◽  
Therapeutic Option ◽  
Critical Role ◽  
The United States ◽  
Brain Disorders ◽  
Mitochondrial Dysfunctions ◽  
Limited Therapeutic Option ◽  
The World

Stroke is a major cause of death and disability in the United States and around the world with limited therapeutic option. Here, we discuss the critical role of mitochondria in stem cell-mediated rescue of stroke brain by highlighting the concept that deleting the mitochondria from stem cells abolishes the cells’ regenerative potency. The application of innovative approaches entailing generation of mitochondria-voided stem cells as well as pharmacological inhibition of mitochondrial function may elucidate the mechanism underlying transfer of healthy mitochondria to ischemic cells, thereby providing key insights in the pathology and treatment of stroke and other brain disorders plagued with mitochondrial dysfunctions.

scholarly journals Do Callable Convertibles Support The Investment Process Of A Company? An Analysis Of The World Market Of Hybrid Debt

2017 ◽  
Vol 20 (2) ◽  
pp. 5-19
Author(s):  
Damian Kaźmierczak
Keyword(s):  
United States ◽  
The United States ◽  
World Market ◽  
Convertible Bonds ◽  
Investment Projects ◽  
Service Companies ◽  
The World ◽  
Investment Process ◽  
A Company

Using a sample of 1,705 convertible bonds issued by manufacturing and service companies from the United States (1,138 issues); Europe (270); and Asia (297) between 2004 and 2014 this paper investigates the role of callable convertibles in the corporate investment process. This research shows first that callable convertibles are used to finance investment projects particularly by American firms which may exercise new investment options to improve poor financial performance. Secondly, the same strategy may be followed by European companies, but they seem not to carry out investments on as large a scale as American firms. Thirdly, the research results do not provide evidence that Asian enterprises use callable convertibles for investment purposes: they likely use these instruments for different reasons.

scholarly journals Ukraine in the Focus of US Foreign Policy Priorities

2020 ◽  
pp. 66-79
Author(s):  
N. Gegelashvili ◽  
◽  
I. Modnikova ◽  
Keyword(s):  
United States ◽  
Soviet Union ◽  
The United States ◽  
Donald Trump ◽  
The Soviet Union ◽  
The Us ◽  
The World ◽  
The Russian Federation ◽  
Radical Transformation

The article analyzes the US policy towards Ukraine dating back from the time before the reunification of Crimea with Russia and up to Donald Trump coming to power. The spectrum of Washington’s interests towards this country being of particular strategic interest to the United States are disclosed. It should be noted that since the disintegration of the Soviet Union Washington’s interest in this country on the whole has not been very much different from its stand on all post-Soviet states whose significance was defined by the U,S depending on their location on the world map as well as on the value of their natural resources. However, after the reunification of Crimea with Russia Washington’s stand on this country underwent significant changes, causing a radical transformation of the U,S attitude in their Ukrainian policy. During the presidency of Barack Obama the American policy towards Ukraine was carried out rather sluggishly being basically declarative in its nature. When President D. Trump took his office Washington’s policy towards Ukraine became increasingly more offensive and was characterized by a rather proactive stance not only because Ukraine became the principal arena of confrontation between the United States and the Russian Federation, but also because it became a part of the US domestic political context. Therefore, an outcome of the “battle” for Ukraine is currently very important for the United States in order to prove to the world its role of the main helmsman in the context of a diminishing US capability of maintaining their global superiority.

Sustainable Agriculture The United States versus the European Union

2010 ◽  
Vol 1 (4) ◽  
pp. 26-31 ◽  
Author(s):  
Carson H. Varner ◽  
Katrin C. Varner
Keyword(s):  
United States ◽  
European Union ◽  
Genetically Modified Crops ◽  
The United States ◽  
World Population ◽  
The European Union ◽  
Sustainability Issue ◽  
The World ◽  
Two Sides

This paper examines developing issues and attitudes that unite and divide the United States and the European Union as the discussion and regulation of agriculture evolves. While some terms, such as “organic,” are defined in law in both the United States and European Union, the increasingly used “sustainability” is an evolving concept. The main sustainability issue is how to provide food and fiber for a rapidly growing world population. In this context, the role of biotechnology is questioned. Americans tend to favor what are sometimes called genetically modified crops, while Europeans remain cautious. Europeans lean more toward organic farming, while Americans assert that much of the world will starve if organic methods are required. This paper reviews the directions that the discussion of these issues is taking and will show areas of agreement and where the two sides diverge.

Spaces of Intentionality: Race, Class, and Horizontality at the United States Social Forum

2008 ◽  
Vol 13 (4) ◽  
pp. 353-372 ◽  
Author(s):  
Jeffrey Juris
Keyword(s):  
United States ◽  
Middle Class ◽  
Open Space ◽  
The United States ◽  
World Social Forum ◽  
High Profile ◽  
Democratic Practice ◽  
The World ◽  
High Level

The World Social Forum process has sought to provide an "open space" for diverse movements to exchange ideas, interact, and coordinate as they build another world. Despite this inclusive impulse, many of the forums have been disproportionately white and middle class. Through an ethnographic account of the 2007 United States Social Forum (USSF) in Atlanta, I examine one high-profile attempt to overcome this lack of diversity by establishing what I refer to as an "intentional" space. I argue that the intentional strategy pursued by USSF organizers achieved a high level of diversity in racial and class terms, but de-emphasized the role of the forum as a "contact zone" for translation, sharing, and exchange among diverse movement sectors. However, given the strong desire to overcome past exclusions among participants, the privileging of intentionality over openness and horizontality was widely viewed as legitimate, which has important implications for democratic practice.

China and the Emergence of Bangladesh: Role of Great Power Global Perceptions

1983 ◽  
Vol 39 (2) ◽  
pp. 137-158 ◽  
Author(s):  
J.N. Mahanty
Keyword(s):  
United States ◽  
South Asia ◽  
South Asian ◽  
The United States ◽  
Strategic Thinking ◽  
Great Power ◽  
The Real ◽  
The World

China's attitude to the Bangladesh Question has evoked a great deal of interest among China watchers. Its professed aim to end exploitation all over the world while extending assistance to West Pakistani exploiters expectedly provoked both academics and activists. Here an attempt is made to examine China's strategic thinking on a vital region, that is South Asia, and the real-politik that pushes into irrelevance the revolutionary pledges. China's failure to forestall the birth of Bangladesh forced it initially to fabricate a fake rationale and finally to reverse, through quick recognition, a hostile population into a friendly nation. History ends where politics begins; history, however, explains the present South Asian political scenario—the emerging triangle of China-Pakistan-Bangladesh, favourably disposed to the United States, while fetching sustenance from an anti-Indian prejudice.

Overview of Planned ASME/VUPRE Conference Meeting on Vulnerability, Uncertainty and Probability Quantification in Regulatory Engineering, and IMECE2012 and FEOFS2013 RE Sessions

2013 ◽  
Author(s):  
Hiroshi Honda
Keyword(s):  
United States ◽  
General Public ◽  
The United States ◽  
Regulatory Agencies ◽  
Offshore Structure ◽  
Fatigue And Fracture ◽  
The World ◽  
Conference Presentations ◽  
Scientists And Engineers

Regulatory engineering came to be increasingly needed by extensive people of our society to maintain safety, security, and sustainability of the environment, economy, energy, mineral and other resources of our planet among others, as engineering is increasingly globalized to meet the needs and wants of a variety of people and society in the world. The ASME/VUPRE Conference on Vulnerability, Uncertainty and Probability Quantification in Regulatory Engineering was to be held in Washington, D. C. on August 16–18, 2012 or thereafter. The current paper provides an overview of the planned conference presentations and discussion, based on the topics planned, and abstracts submitted among others, as well as those for IMECE2012 Session 5-7-2 Globalization of Regulatory Engineering, and the author’s paper on fatigue and fracture issues of an offshore structure, etc., and role of regulatory engineering, prepared for the 9th International Conference on Fracture and Strength of Solids (FEOFS2013) on June 9–13, 2013 in Jeju, South Korea. Possible impacts of the outcome on the regulatory agencies, regulated communities, scientists and engineers, and general public in the United States, Europe and Japan among other nations and regions are also discussed.

On «particularity» and «exceptionalism» of the United States of America

2020 ◽  
Vol 26 (4) ◽  
pp. 68-79
Author(s):  
Vladimir F. Pecheritsa
Keyword(s):  
United States ◽  
United States Of America ◽  
The United States ◽  
Foreign Affairs ◽  
Contemporary World ◽  
The World

The article analyzes the hegemonic policy of the largest and most influential state in the world – the United States, supported under the justified concept of “peculiarity” and exclusivity of America. Using this term, Washington imposes its only “correct” and necessary policy for the development of countries and peoples. Showing numerous examples, the author exposes the deceit and duplicity of such a policy, its rejection by most countries of the world. The article is intended for specialists in foreign affairs and those who study the place and role of the United States in the contemporary world.

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