ABO Blood Groups in Hypophyseal Adenomas

1964 ◽  
Vol 50 (6) ◽  
pp. 469-472 ◽  
Author(s):  
Giorgio Iraci ◽  
Gian Guido Toffolo

The statistical significance of variations in Wood group distribution among patients affected by chromophobe pituitary adenoma has been debated in recent reports. One hundred and fifty hypophyseal tumors (117 chromophobe adenomas and 33 adenomas of other histological type), operated for the first time at the Institute of Neurosurgery of the University of Padua, have been collected for such an analysis. No difference of statistical significance was detected by the present survey, although this fact is probably due to the small numbers of patients in each subgroup.

1964 ◽  
Vol 50 (6) ◽  
pp. 473-476 ◽  
Author(s):  
Giorgio Iraci ◽  
Gian Guido Toffolo

Statistical analysis of the variations in blood group distribution among 470 consecutive cases of meningioma, operated at the Institute of Neurosurgery of the University of Padua, shows a statistically significant increase in the frequency of group B.


Neurosurgery ◽  
1988 ◽  
Vol 22 (5) ◽  
pp. 886-891 ◽  
Author(s):  
Zhen Min Sun ◽  
Shigeru Genka ◽  
Nobuyuki Shitara ◽  
Atsuo Akanuma ◽  
Kintomo Takakura

Abstract Fifty-seven cases of oligodendroglioma (including eight cases of malignant oligodendroglioma) treated at the University of Tokyo Hospital between 1961 and 1985 were analyzed for factors influencing the survival rate. Factors related to a poor outcome were findings of malignancy and symptoms of dementia. Survival rate and postoperative survival period were not influenced significantly by radiation therapy, extent of resection, tumor characteristics, or ABO blood groups.


2020 ◽  
Author(s):  
Minfei Peng ◽  
Shigao Huang ◽  
Shitu Zhu ◽  
Chaochao Chen ◽  
Jiajia Qin ◽  
...  

Abstract Background Since December 2019, the novel coronavirus pandemic (COVID-19) has become a global health emergency. To date, studies on the correlation between ABO blood groups and COVID-19 infected risk had rarely reported. This study aimed to describe the ABO blood groups distribution and association to low risk of COVID-19 infection for effectively concerning about the susceptible population. Methods We included 138 COVID-19 diagnosed patients and 82 non- COVID-19 patients between January 21 and February 20, 2020.We compared ABO blood group distribution, gender distribution and correlation analysis in Severe, Non-severe and Non-COVID19 patients, and analyzed the laboratory indexes of type O and non-type O groups in COVID19 patients. Results The laboratory results were significantly difference between type O and non-type O COVID19 patients (P < 0.05). Patients with blood type O had lower risk of severe COVID-19 infection (χ2 = 4.066, p = 0.044, OR = 0.380), and especially, female with the type O blood had lower risk in deteriorating severe COVID19 infection (p = 0.049). Conclusion Patients with the blood group of type O had relatively lower risk of COVID19 infection, especially, female with the type O blood had lower risk in deteriorating severe COVID19 infection. We should concern more to the patients with non-type O blood to minimize the risk of COVID19 infection.


BMJ ◽  
1960 ◽  
Vol 1 (5180) ◽  
pp. 1163-1166 ◽  
Author(s):  
I. Aird ◽  
D. R. Lee ◽  
J. A. F. Roberts

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Francisco Ujueta ◽  
Michael A Nardi ◽  
Yu Guo ◽  
Adriana Perez ◽  
Maya Rubin ◽  
...  

Background: ABO blood groups have been associated with functional effects on factor VIII (FVIII), von Willebrand factor (vWF) and incident atherothrombosis. This study sought to examine the association between ABO blood type, FVIII and vWF in patients undergoing vascular surgery. Method: This is a retrospective analysis of data from a cohort of 181 patients undergoing elective vascular surgery. ABO blood type, FVIII and vWF was measured before surgery. The primary end point was the occurrence of MACE (defined as myocardial necrosis, myocardial infarction, stroke or death) within 30-days after surgery. Multivariable logistic regression modeling was used to estimate odds of MACE. Results: The mean age was 71.6 ± 9.8 and 29% were female. Non-O blood type was present in 105 patients (70 A, 27 B, 8 AB) and type O in 76 patients. Non-O had higher FVIII (128.2 ± 44.7 vs 112.4 ± 42.4, P<0.001) and vWF (176.0 ± 54.0 vs 133.2 ± 41.0, P<0.001) than type O. Thirty day MACE occurred in 38 (21.0%) patients; 25% in non-O and 15.8% in type O (P=0.13). After adjustment for age, sex, race, prior coronary artery disease and heart failure, patients with non-O blood type (vs. O) had a higher incidence of 30-day MACE (odds ratio 2.1, 95% CI 0.9 to 5.1, P=0.08) although statistical significance was not reached. There was no significant association between FVIII and vWF and 30-day MACE. Conclusions: Non-O blood type was associated with higher levels of FVIII and vWF and a trend towards increased 30-day MACE in patients undergoing vascular surgery. Larger studies across of ABO blood groups and perioperative events in different types of surgeries are warranted.


2010 ◽  
Vol 6 (S269) ◽  
pp. 3-6
Author(s):  
George V. Coyne

AbstractDuring the very last year of what he himself described “as the best [eighteen] years of his life” spent at the University of Padua, Galileo first observed the heavens with a telescope. In order to appreciate the marvel and the true significance of those observations we must appreciate both the intellectual climate in Europe and the critical intellectual period through which Galileo himself was passing at the time those observations were made. Through his studies on motion Galileo had come to have serious doubts about the Aristotelian concept of nature. What he sensed was lacking was a true physics. He was very acute, therefore, when he came to sense the significance of his observations of the moon, of the phases of Venus, of the moons of Jupiter and of the Milky Way. The preconceptions of the Aristotelians were crumbling before his eyes. He had remained silent long enough, over a three month period, in his contemplations of the heavens. It was time to organize his thoughts and tell what he had seen and what he thought it meant. It was time to publish! In so doing he would become one of the pioneers of modern science. For the first time in over 2,000 years new significant observational data had been put at the disposition of anyone who cared to think, not in abstract preconceptions but in obedience to what the universe had to say about itself.


2003 ◽  
Vol 07 (01) ◽  
pp. 9-19
Author(s):  
Antonio Favaro

Editor's Note: Until the 1990s, there was no published work on Galileo's astrology except for the two papers published here by Antonio Favaro in Italian. These are presented here in English translation for the first time. Part 1: 'Galileo Astrologo' Editor's Note: This trailblazing essay by Antonio Favaro was composed a decade before he first started to publish his twenty-volume Opere* of Galileo's complete works, and was published in the periodical Mente e Cuore in 1881. Greatly ignored by scholars, it has of late been alluded to by Poppi and Ernst. The footnotes differ from the original in being numbered sequentially through the whole article; endnotes are added by Nick Kollerstrom. Part 2: Mathematics at the University of Padua before Galileo Editor's Note: Padua was Europe's second oldest university, after Bologna. One seeks in vain for anything written about its chair of mathematics, beyond this single essay by Favaro. This neglect is presumably on account of the central role which it assigned to astrology, down through the centuries. Santillana's essay The Crime of Galileo makes what one must view as a fictional statement, that,when Galileo accepted the Chair at Padua in 1592, 'The chair of mathematics then covered the teaching of geometry, astronomy, military engineering, and fortification' . That could describe Padua's mathematics chair a century later, perhaps in the 18th century. The first two paragraphs of Favaro's essay are here translated, and in addition two of Galileo's letters about his mathematics lectures are here reproduced, showing that the students who attended them were either philosophers or medical doctors - the latter, in order to learn how to erect a horoscope for the onset of disease.


2020 ◽  
Author(s):  
Manal Ibrahim Kosta ◽  
Pascal Bailly ◽  
Monique Silvy ◽  
Noemie Saut ◽  
Pierre Suchon ◽  
...  

AbstractIntroductionABO blood group influence the risk of venous thrombosis (VT) by modifying A and B glycosyltransferases (AGT and BGT) activities that further modulates Factor VIII (FVIII) and von Willebrand Factor (VWF) plasma levels. The aim of this work was to evaluate the association of plasma GTs activities with VWF/FVIII plasma levels and VT risk in a case-control study.Materials and Methods420 cases were matched with 420 controls for age and ABO blood group. GT activities in plasma were measured using the quantitative transfer of tritiated N-acetylgalactosamine or galactose to the 2’-fucosyl-lactose and expressed in disintegration per minute/30µL of plasma and 2 hours of reaction (dpm/30µL/2H). FVIII and VWF plasma levels were respectively measured using human FVIII-deficient plasma in a 1-stage factor assay and STA LIATEST VWF (Diagnostica Stago).ResultsA and B GT activities were significantly lower in cases than in controls (8119±4027 vs 9682±4177 dpm/30µL/2H, p=2.03 × 10−5, and 4931±2305 vs 5524±2096 dpm/30µL/2H, p=0.043 respectively). This association was observed whatever the ABO blood groups. The ABO A1 blood group was found to explain∼80% of AGT activity. After adjusting for ABO blood groups, AGT activity was not correlated to VWF/FVIII plasma levels. Conversely, there was a moderate correlation (ρ∼0.30) between BGT activity and VWF/ FVIII plasma levels in B blood group carriers.ConclusionThis work showed, for the first time, that GT activities were decreased in VT patients in comparison to controls with the same ABO blood group. The biological mechanisms responsible for this association remained to be determined.


2012 ◽  
Vol 6 (10) ◽  
pp. 727-733 ◽  
Author(s):  
Aida Sadikh Badiane ◽  
Ousmane Sarr ◽  
Awa Bineta Deme ◽  
Ambroise Dioum Ahouidi ◽  
Papa Elhadji Omar Gueye ◽  
...  

Introduction: The study was conducted to determine for the first time the association between the erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in malaria patients living in Thies, a hypoendemic area in Senegal. Methodology: In 2007, the EBA-175 alleles and blood group types were determined by nested PCR and the Simonin test respectively in blood samples obtained from uncomplicated Plasmodium falciparum malaria positive patients. Results and conclusion: In total, 129 patients were enrolled in the study. The EBA-175 genotyping showed a prevalence of 67.45% for the F-allele, 27.90% for the C-allele and 4.65% of mixed C+F infection. The distribution of the ABO blood group type showed 59.8% for the O group, 19.7% for the A group, 17.2% for the B group, and 3.3% for the AB group. No correlation was noted between the EBA-175 alleles and either the blood group type or parasitemia.


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