Experimental Myringoplasty

1980 ◽  
Vol 3 (6) ◽  
pp. 354-357 ◽  
Author(s):  
L. Feenstra ◽  
B.W.C. Van Der Ven ◽  
F.E. Kohn ◽  
J. Feijen
Keyword(s):  
Lactic Acid ◽  
Bisphenol A ◽  
Tympanic Membrane ◽  
Biodegradable Polymers ◽  
Glycolic Acid ◽  
Tissue Reaction ◽  
Biodegradable Poly ◽  
One Year ◽  
Poly Carbonate ◽  
Tympanic Membranes

Artificial eardrums made from biodegradable poly(D, L-lactic acid), poly(glycolic acid) and poly(ß-benzyl-L-aspartate-co-L-leucine) 50/50, and made from the microporous poly(tetrafluoroethylene) and bisphenol-A poly(carbonate) membranes were implanted into the ear and as a reference subcutaneously in rats. The implants were histologically examined for periods up to one year. From the biodegradable polymers studied the poly(ß-benzyl-L-aspartate-co-L-leucine) 50/50 evoked the least tissue reaction and the newly formed tympanic membranes are the best in terms of thickness and overall integrity. The microporous poly(tetrafluoroethylene) membrane can be considered as a valuable support for the formation of a reinforced tympanic membrane.

Biodegradation and tissue reaction to intravitreous biodegradable poly(D,L-lactic-co-glycolic)acid microspheres

1995 ◽  
Vol 14 (9) ◽  
pp. 761-768 ◽  
Author(s):  
Giovanni G. Giordano ◽  
Patricia Chevez-Barrios ◽  
Miguel F. Refojo ◽  
Charles A. Garcia
Keyword(s):  
Glycolic Acid ◽  
Tissue Reaction ◽  
Biodegradable Poly

Studies on the interactions of CO2 with biodegradable poly(dl-lactic acid) and poly(lactic acid-co-glycolic acid) copolymers using high pressure ATR-IR and high pressure rheology

Polymer ◽  
2010 ◽  
Vol 51 (6) ◽  
pp. 1425-1431 ◽  
Author(s):  
Hongyun Tai ◽  
Clare E. Upton ◽  
Lisa J. White ◽  
Ronny Pini ◽  
Giuseppe Storti ◽  
...  
Keyword(s):  
High Pressure ◽  
Lactic Acid ◽  
Glycolic Acid ◽  
Poly Lactic Acid ◽  
Biodegradable Poly

scholarly journals Simultaneous HPLC-UV Determination of Lactic Acid, Glycolic Acid, Glycolide, Lactide and Ethyl Acetate in Monomers for Producing Biodegradable Polymers

2014 ◽  
Vol 10 ◽  
pp. 244-251 ◽  
Author(s):  
M.K. Zamanova ◽  
V.N. Glotova ◽  
T.N. Izhenbina ◽  
D.S. Krutas ◽  
V.T. Novikov
Keyword(s):  
Lactic Acid ◽  
Ethyl Acetate ◽  
Biodegradable Polymers ◽  
Glycolic Acid

Biodegradable poly(lactide-co-glycolide-co-ε-caprolactone) block copolymers – evaluation as drug carriers for a localized and sustained delivery system

2015 ◽  
Vol 3 (41) ◽  
pp. 8143-8153 ◽  
Author(s):  
Ji Hoon Park ◽  
Hwi Ju Kang ◽  
Doo Yeon Kwon ◽  
Bo Keun Lee ◽  
Bong Lee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Lactic Acid ◽  
Drug Delivery Systems ◽  
Glycolic Acid ◽  
Drug Carrier ◽  
Drug Carriers ◽  
Poly Lactic Acid ◽  
Sustained Delivery ◽  
System P ◽  
Biodegradable Poly

To develop an appropriate drug carrier for drug delivery systems, we prepared random poly(lactide-co-glycolide-co-ε-caprolactone) (PLGC) copolymers in comparison to commercial poly(lactic acid-co-glycolic acid) (PLGA) grades.

scholarly journals Biodegradable poly (lactic acid-co-glycolic acid) scaffolds as carriers for genetically-modified fibroblasts

PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0174860 ◽  
Author(s):  
Tatjana Perisic ◽  
Ziyang Zhang ◽  
Peter Foehr ◽  
Ursula Hopfner ◽  
Kathrin Klutz ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Glycolic Acid ◽  
Genetically Modified ◽  
Poly Lactic Acid ◽  
Biodegradable Poly

scholarly journals Mechanical Properties and Bioactivity of Poly(Lactic Acid) Composites Containing Poly(Glycolic Acid) Fiber and Hydroxyapatite Particles

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 249
Author(s):  
Han-Seung Ko ◽  
Sangwoon Lee ◽  
Doyoung Lee ◽  
Jae Young Jho
Keyword(s):  
Mechanical Properties ◽  
Lactic Acid ◽  
Flexural Strength ◽  
Interfacial Adhesion ◽  
Glycolic Acid ◽  
Compact Bone ◽  
Poly Lactic Acid ◽  
Coupling Reactions ◽  
The Poor ◽  
Human Compact Bone

To enhance the mechanical strength and bioactivity of poly(lactic acid) (PLA) to the level that can be used as a material for spinal implants, poly(glycolic acid) (PGA) fibers and hydroxyapatite (HA) were introduced as fillers to PLA composites. To improve the poor interface between HA and PLA, HA was grafted by PLA to form HA-g-PLA through coupling reactions, and mixed with PLA. The size of the HA particles in the PLA matrix was observed to be reduced from several micrometers to sub-micrometer by grafting PLA onto HA. The tensile and flexural strength of PLA/HA-g-PLA composites were increased compared with those of PLA/HA, apparently due to the better dispersion of HA and stronger interfacial adhesion between the HA and PLA matrix. We also examined the effects of the length and frequency of grafted PLA chains on the tensile strength of the composites. By the addition of unidirectionally aligned PGA fibers, the flexural strength of the composites was greatly improved to a level comparable with human compact bone. In the bioactivity tests, the growth of apatite on the surface was fastest and most uniform in the PLA/PGA fiber/HA-g-PLA composite.

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